Evaluation of the immuno-modulating activity of some active principles isolated from the fruiting bodies of Antrodia camphorata

Chinese Pharmaceutical Journal

Volumn 55, Issue 5, 2003, Pages 313-318

  Shen, Yuh Chiang ^a   Chen, Chieh Fu ^a   Wang, Yea Hwey ^b   Chang, Tun Tschu ^c   Chou, Cheng Jen ^a  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAIWAN FORESTRY RESEARCH INSTITUTE   (Taiwan)

Author keywords

Antrodia camphorata; Mononuclear cell; N formyl methionyl leucyl phenylalanine; Neutrophil; Phorbol 12 myristate 13 acetate; Reactive oxygen species

Indexed keywords

ALCOHOLS; CELLS; INORGANIC ACIDS; LIVING SYSTEMS STUDIES;

MODULATING ACTIVITY; SULPHURENIC ACID (SA);

DRUG PRODUCTS;

ANTCIN C; ANTIOXIDANT; ANTRODIA CAMPHORATA EXTRACT; AUTACOID; DEHYDROEBURICOIC ACID; EBURICOIC ACID; ERGOSTANE DERIVATIVE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; HERBACEOUS AGENT; IMMUNOMODULATING AGENT; LANOSTANE DERIVATIVE; LUCIGENIN; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; SULFURENIC ACID; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ANTRODIA CAMPHORATA; ARTICLE; BIOSYNTHESIS; CELL ASSAY; CELL VIABILITY; CHEMOLUMINESCENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; FLOW CYTOMETRY; FRUITING BODY; HUMAN; HUMAN CELL; IC 50; IMMUNE RESPONSE; IMMUNOMODULATION; LEUKOCYTE ACTIVATION; MEDICINAL PLANT; NEUTROPHIL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; SIGNAL TRANSDUCTION;

EID: 3142548798     PISSN: 10161015     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Tsai, Z. T.; Liaw, S. L. The use and the effect of Ganoderma. San Yun Press, Taichung, Taiwan, 1985; pp 116.
2. Shen, C. C.; Kuo, Y. C.; Huang, R. L.; Lin, L. C.; Dong, M. J.; Chang, T. T.; Chou, C. J. New ergostane and lanostane from Antrodia camphorata. J. Chin. Med. 2003, 14, 247-258.
3. Chen, C. H.; Yang, S. W.; Shen, Y. C. New steroids from Antrodia cinnamomea, a fungal parasite of Cinnamomun micranthum. J. Nat. Prod. 1995, 58, 1655-1661.
4. Casimir, C. M.; Teahan, C. G. The respiratory burst of neutrtophils and its deficiency. In: Immunopharmacology of Neutrophils, Hellewell, P. G.; Williams, T. J., Eds; Acedemic Press, San Diego, 1994; pp 27-54.
5. Wardlaw, A. J.; Walsh, G. M. Neutrophil adhesion receptor. In: Immunopharmacology of Neutrophils, Hellewell, P. G.; Williams, T. J., Eds; Acedemic Press, San Diego, 1994; pp 134-137.
6. Cuzzocrea, S.; Riley, D. P.; Caputi, A. P.; Salvemini, D. Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol. Rev. 2001, 53, 135-159.
7. Middleton, E. Jr.; Kandaswami, C.; Theoharides, T. C. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 2000, 52, 673-751.
8. Shen, Y. C.; Chiou, W. F.; Chou, Y. C.; Chen, C. F. Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes. Eur. J. Pharmacol. 2003, 465, 171-181.
9. Parij, N.; Nagy, A-M.; Fondu, P.; Neve, J. Effects of non-steroidal anti-inflammatory drugs on the luminol and lucigenin amplified chemiluminescence of human neutrophils. Eur. J. Pharmacol. 1998, 352, 299-305.
10. Ormerod, M. G. Further applications to cell biology. In: Flow cytometry, Ormerod, M. G., Eds; Oxford University Press, UK, 2000; pp 249-250.
11. Williams, F. M. Role of neutrophils in respiratory injury. In: Immunopharmacology of Neutrophils, Hellewell, P. G.; Williams, T. J., Eds; Acedemic Press, San Dieg, 1994; pp 245-257.
12. Nathan, C. Points of control in inflammation. Nature 2002, 420, 846-852.
13. Simons, J. M.; Hart, B. A.; Ip Vai Ching, T. R.; Van Dijk, H. Labadie, R. P. Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils. Free Radical Biol. Med. 1990, 8, 251-258.
14. Wang, Q.; Doerschuk, C. M. Neutrophil-induced changes in the biomechanical properties of endothelial cells: roles of ICAM-1 and reactive oxygen species. J. Immunol. 2000, 164, 6487-6494.
15. Shen, Y. C.; Chou, C. J.; Chiou, W. F.; Chen, C. F. Anti-inflammatory effects of the partially purified extract of Radix Stephaniae tetrandrae: comparative studies with its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions. Mol. Pharmacol. 2001, 60, 1083-1090.