메뉴 건너뛰기




Volumn 152, Issue 2, 2011, Pages 447-456

The transcription factor B-cell lymphoma (BCL)-6 modulates pancreatic β-cell inflammatory responses

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DEATH RECEPTOR 5; FAS ANTIBODY; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROLACTIN; PROTEIN BCL 6; TRANSCRIPTION FACTOR JUNB;

EID: 79951655090     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-0790     Document Type: Article
Times cited : (8)

References (67)
  • 1
    • 0035668779 scopus 로고    scopus 로고
    • A choice of death - The signal-transduction of immune-mediated beta-cell apoptosis
    • DOI 10.1007/s001250100021
    • Eizirik DL, Mandrup-Poulsen T 2001 A choice of death - the signal-transduction of immune-mediated β-cell apoptosis. Diabetologia 44:2115-2133 (Pubitemid 34015464)
    • (2001) Diabetologia , vol.44 , Issue.12 , pp. 2115-2133
    • Eizirik, D.L.1    Mandrup-Poulsen, T.2
  • 2
    • 67649364114 scopus 로고    scopus 로고
    • The role of inflammation in insulitis and β-cell loss in type 1 diabetes
    • Eizirik DL, Colli ML, Ortis F 2009 The role of inflammation in insulitis and β-cell loss in type 1 diabetes. Nat Rev Endocrinol 5:219-226
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 219-226
    • Eizirik, D.L.1    Colli, M.L.2    Ortis, F.3
  • 3
    • 0035856952 scopus 로고    scopus 로고
    • β-cell death during progression to diabetes
    • Mathis D, Vence L, Benoist C 2001 β-cell death during progression to diabetes. Nature 414:792-798
    • (2001) Nature , vol.414 , pp. 792-798
    • Mathis, D.1    Vence, L.2    Benoist, C.3
  • 6
    • 0035488777 scopus 로고    scopus 로고
    • Inhibition of Cytokine-Induced NF-κB Activation by Adenovirus-Mediated Expression of a NF-κB Super-Repressor Prevents β-Cell Apoptosis
    • Heimberg H, Heremans Y, Jobin C, Leemans R, Cardozo AK, Darville M, Eizirik DL 2001 Inhibition of cytokine-induced NF-κB activation by adenovirus-mediated expression of a NF-κB super-repressor prevents β-cell apoptosis. Diabetes 50:2219-2224 (Pubitemid 33641904)
    • (2001) Diabetes , vol.50 , Issue.10 , pp. 2219-2224
    • Heimberg, H.1    Heremans, Y.2    Jobin, C.3    Leemans, R.4    Cardozo, A.K.5    Darville, M.6    Eizirik, D.L.7
  • 7
    • 0033625677 scopus 로고    scopus 로고
    • Growths, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor β(δ)
    • DOI 10.1128/MCB.20.14.5119-5128.2000
    • Peters JM, Lee SS, Li W, Ward JM, Gavrilova O, Everett C, Reitman ML, Hudson LD, Gonzalez FJ 2000 Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator- activated receptor β(δ). Mol Cell Biol 20: 5119-5128 (Pubitemid 30431565)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.14 , pp. 5119-5128
    • Peters, J.M.1    Lee, S.S.T.2    Li, W.3    Ward, J.M.4    Gavrilova, O.5    Everett, C.6    Reitman, M.L.7    Hudson, L.D.8    Gonzalez, F.J.9
  • 8
    • 9144262378 scopus 로고    scopus 로고
    • Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
    • DOI 10.1038/nm1116
    • Cheng L, Ding G, Qin Q, Huang Y, Lewis W, He N, Evans RM, Schneider MD, Brako FA, Xiao Y, Chen YE, Yang Q 2004 Cardiomyocyte- restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nat Med 10:1245-1250 (Pubitemid 39540443)
    • (2004) Nature Medicine , vol.10 , Issue.11 , pp. 1245-1250
    • Cheng, L.1    Ding, G.2    Qin, Q.3    Huang, Y.4    Lewis, W.5    He, N.6    Evans, R.M.7    Schneider, M.D.8    Brako, F.A.9    Xiao, Y.10    Chen, Y.E.11    Yang, Q.12
  • 10
    • 0142116239 scopus 로고    scopus 로고
    • Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ
    • DOI 10.1126/science.1087344
    • Lee CH, Chawla A, Urbiztondo N, Liao D, Boisvert WA, Evans RM, Curtiss LK 2003 Transcriptional repression of atherogenic inflammation: modulation by PPARδ. Science 302:453-457 (Pubitemid 37296272)
    • (2003) Science , vol.302 , Issue.5644 , pp. 453-457
    • Lee, C.-H.1    Chawla, A.2    Urbiztondo, N.3    Liao, D.4    Boisvert, W.A.5    Evans, R.M.6
  • 11
    • 0028822226 scopus 로고
    • The LAZ3/BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: A novel function for the BTB/POZ domain as an autonomous repressing domain
    • Deweindt C, Albagli O, Bernardin F, Dhordain P, Quief S, Lantoine D, Kerckaert JP, Leprince D 1995 The LAZ3/BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: a novel function for the BTB/POZ domain as an autonomous repressing domain. Cell Growth Differ 6:1495-1503
    • (1995) Cell Growth Differ , vol.6 , pp. 1495-1503
    • Deweindt, C.1    Albagli, O.2    Bernardin, F.3    Dhordain, P.4    Quief, S.5    Lantoine, D.6    Kerckaert, J.P.7    Leprince, D.8
  • 13
    • 0029899571 scopus 로고    scopus 로고
    • Transcriptional repression by the proto-oncogene BCL-6
    • Seyfert VL, Allman D, He Y, Staudt LM 1996 Transcriptional repression by the proto-oncogene BCL-6. Oncogene 12:2331-2342 (Pubitemid 26192713)
    • (1996) Oncogene , vol.12 , Issue.11 , pp. 2331-2342
    • Seyfert, V.L.1    Allman, D.2    He, Y.3    Staudt, L.M.4
  • 15
    • 35748984132 scopus 로고    scopus 로고
    • Functional analysis of the role of POK transcriptional repressors
    • DOI 10.1093/bfgp/elm002
    • Costoya JA 2007 Functional analysis of the role of POK transcriptional repressors. Brief Funct Genomic Proteomic 6:8-18 (Pubitemid 351721044)
    • (2007) Briefings in Functional Genomics and Proteomics , vol.6 , Issue.1 , pp. 8-18
    • Costoya, J.A.1
  • 16
    • 0032531688 scopus 로고    scopus 로고
    • The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression
    • DOI 10.1093/nar/26.20.4645
    • Dhordain P, Lin RJ, Quief S, Lantoine D, Kerckaert JP, Evans RM, Albagli O 1998 The LAZ3(BCL-6) oncoprotein recruits a SMRT/ mSIN3A/histone deacetylase containing complex to mediate transcriptional repression. Nucleic Acids Res 26:4645-4651 (Pubitemid 28466611)
    • (1998) Nucleic Acids Research , vol.26 , Issue.20 , pp. 4645-4651
    • Dhordain, P.1    Lin, R.J.2    Quief, S.3    Lantoine, D.4    Kerckaert, J.-P.5    Evans, R.M.6    Albagli, O.7
  • 18
    • 0032538429 scopus 로고    scopus 로고
    • Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARα, and BCL-6
    • DOI 10.1074/jbc.273.42.27695
    • Wong CW, Privalsky ML 1998 Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARα, and BCL-6. J Biol Chem 273:27695-27702 (Pubitemid 28500495)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.42 , pp. 27695-27702
    • Wong, C.-W.1    Privalsky, M.L.2
  • 19
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • DOI 10.1126/science.276.5312.589
    • Dent AL, Shaffer AL, Yu X, Allman D, Staudt LM 1997 Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 276:589-592 (Pubitemid 27193682)
    • (1997) Science , vol.276 , Issue.5312 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 22
    • 0033680860 scopus 로고    scopus 로고
    • BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
    • Shaffer AL, Yu X, He Y, Boldrick J, Chan EP, Staudt LM 2000 BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity 13:199-212
    • (2000) Immunity , vol.13 , pp. 199-212
    • Shaffer, A.L.1    Yu, X.2    He, Y.3    Boldrick, J.4    Chan, E.P.5    Staudt, L.M.6
  • 23
    • 0027306091 scopus 로고
    • LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas
    • DOI 10.1038/ng0993-66
    • Kerckaert JP, Deweindt C, Tilly H, Quief S, Lecocq G, Bastard C 1993 LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas. Nat Genet 5:66-70 (Pubitemid 23261521)
    • (1993) Nature Genetics , vol.5 , Issue.1 , pp. 66-70
    • Kerckaert, J.-P.1    Deweindt, C.2    Tilly, H.3    Quief, S.4    Lecocq, G.5    Bastard, C.6
  • 27
    • 0033552811 scopus 로고    scopus 로고
    • The proto-oncogene Bcl6 inhibits apoptotic cell death in differentiation-induced mouse myogenic cells
    • DOI 10.1038/sj.onc.1202306
    • Kumagai T, Miki T, Kikuchi M, Fukuda T, Miyasaka N, Kamiyama R, Hirosawa S 1999 The proto-oncogene Bcl6 inhibits apoptotic cell death in differentiation-induced mouse myogenic cells. Oncogene 18:467-475 (Pubitemid 29060622)
    • (1999) Oncogene , vol.18 , Issue.2 , pp. 467-475
    • Kumagai, T.1    Miki, T.2    Kikuchi, M.3    Fukuda, T.4    Miyasaka, N.5    Kamiyama, R.6    Hirosawa, S.7
  • 28
    • 0033552949 scopus 로고    scopus 로고
    • Adenovirus-mediated high expression of BCL-6 in CV-1 cells induces apoptotic cell death accompanied by down-regulation of BCL-2 and BCL-X(L)
    • DOI 10.1038/sj.onc.1202334
    • Yamochi T, Kaneita Y, Akiyama T, Mori S, Moriyama M 1999 Adenovirus-mediated high expression of BCL-6 in CV-1 cells induces apoptotic cell death accompanied by down-regulation of BCL-2 and BCL-X(L). Oncogene 18:487-494 (Pubitemid 29060624)
    • (1999) Oncogene , vol.18 , Issue.2 , pp. 487-494
    • Yamochi, T.1    Kaneita, Y.2    Akiyama, T.3    Mori, S.4    Moriyama, M.5
  • 29
    • 0033539126 scopus 로고    scopus 로고
    • Overexpressed BCL6 (LAZ3) oncoprotein triggers apoptosis, delays S phase progression and associates with replication foci
    • DOI 10.1038/sj.onc.1202892
    • Albagli O, Lantoine D, Quief S, Quignon F, Englert C, Kerckaert JP, Montarras D, Pinset C, Lindon C 1999 Overexpressed BCL6 (LAZ3) oncoprotein triggers apoptosis, delays S phase progression and associates with replication foci. Oncogene 18:5063-5075 (Pubitemid 29443752)
    • (1999) Oncogene , vol.18 , Issue.36 , pp. 5063-5075
    • Albagli, O.1    Lantoine, D.2    Quief, S.3    Quignon, F.4    Englert, C.5    Kerckaert, J.-P.6    Montarras, D.7    Pinset, C.8    Lindon, C.9
  • 30
    • 33748489928 scopus 로고    scopus 로고
    • BCL-6: A possible missing link for anti-inflammatory PPAR-δ signalling in pancreatic beta cells
    • DOI 10.1007/s00125-006-0366-5
    • Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL, Cnop M 2006 BCL-6: a possible missing link for anti-inflammatory PPAR-δ signalling in pancreatic β-cells. Diabetologia 49: 2350-2358 (Pubitemid 44359096)
    • (2006) Diabetologia , vol.49 , Issue.10 , pp. 2350-2358
    • Kharroubi, I.1    Lee, C.-H.2    Hekerman, P.3    Darville, M.I.4    Evans, R.M.5    Eizirik, D.L.6    Cnop, M.7
  • 31
    • 38449099624 scopus 로고    scopus 로고
    • Menin controls growth of pancreatic β-cells in pregnant mice and promotes gestational diabetes mellitus
    • DOI 10.1126/science.1146812
    • Karnik SK, Chen H, McLean GW, Heit JJ, Gu X, Zhang AY, Fontaine M, Yen MH, Kim SK 2007 Menin controls growth of pancreatic β-cells in pregnant mice and promotes gestational diabetes mellitus. Science 318:806-809 (Pubitemid 351411773)
    • (2007) Science , vol.318 , Issue.5851 , pp. 806-809
    • Karnik, S.K.1    Chen, H.2    McLean, G.W.3    Heit, J.J.4    Gu, X.5    Zhang, A.Y.6    Fontaine, M.7    Yen, M.H.8    Kim, S.K.9
  • 32
    • 71049185095 scopus 로고    scopus 로고
    • The FoxO/Bcl-6/cyclin D2 pathway mediates metabolic and growth factor stimulation of proliferation in Min6 pancreatic β-cells
    • Glauser DA, Schlegel W 2009 The FoxO/Bcl-6/cyclin D2 pathway mediates metabolic and growth factor stimulation of proliferation in Min6 pancreatic β-cells. J Recept Signal Transduct Res 29:293-298
    • (2009) J Recept Signal Transduct Res , vol.29 , pp. 293-298
    • Glauser, D.A.1    Schlegel, W.2
  • 33
    • 0026550830 scopus 로고
    • Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines
    • Asfari M, Janjic D, Meda P, Li G, Halban PA, Wollheim CB 1992 Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130:167-178
    • (1992) Endocrinology , vol.130 , pp. 167-178
    • Asfari, M.1    Janjic, D.2    Meda, P.3    Li, G.4    Halban, P.A.5    Wollheim, C.B.6
  • 34
    • 33746594835 scopus 로고    scopus 로고
    • Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-κB activation
    • DOI 10.1210/me.2005-0268
    • Ortis F, Cardozo AK, Crispim D, Störling J, Mandrup-Poulsen T, Eizirik DL 2006 Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory NF-κB activation. Mol Endocrinol 20:1867-1879 (Pubitemid 44148090)
    • (2006) Molecular Endocrinology , vol.20 , Issue.8 , pp. 1867-1879
    • Ortis, F.1    Cardozo, A.K.2    Crispim, D.3    Storling, J.4    Mandrup-Poulsen, T.5    Eizirik, D.L.6
  • 35
    • 0028084965 scopus 로고
    • Effect of nutrients, hormones and serum on survival of rat islet beta cells in culture
    • Ling Z, Hannaert JC, Pipeleers D 1994 Effect of nutrients, hormones and serum on survival of rat islet beta-cells in culture. Diabetologia 37:15-21 (Pubitemid 24044702)
    • (1994) Diabetologia , vol.37 , Issue.1 , pp. 15-21
    • Ling, Z.1    Hannaert, J.C.2    Pipeleers, D.3
  • 37
    • 0031827241 scopus 로고    scopus 로고
    • Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells
    • DOI 10.1007/s001250051036
    • Darville MI, Eizirik DL 1998 Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells. Diabetologia 41:1101-1108 (Pubitemid 28394417)
    • (1998) Diabetologia , vol.41 , Issue.9 , pp. 1101-1108
    • Darville, M.I.1    Eizirik, D.L.2
  • 38
    • 0035432603 scopus 로고    scopus 로고
    • Cytokine Induction of Fas Gene Expression in Insulin-Producing Cells Requires the Transcription Factors NF-κB and C/EBP
    • Darville MI, Eizirik DL 2001 Cytokine induction of Fas gene expression in insulin-producing cells requires the transcription factors NF-κB and C/EBP. Diabetes 50:1741-1748 (Pubitemid 33641591)
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1741-1748
    • Darville, M.I.1    Eizirik, D.L.2
  • 39
    • 0242363618 scopus 로고    scopus 로고
    • Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells
    • Kutlu B, Cardozo AK, Darville MI, Kruhøffer M, Magnusson N, Ørntoft T, Eizirik DL 2003 Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells. Diabetes 52:2701-2719
    • (2003) Diabetes , vol.52 , pp. 2701-2719
    • Kutlu, B.1    Cardozo, A.K.2    Darville, M.I.3    Kruhøffer, M.4    Magnusson, N.5    Ørntoft, T.6    Eizirik, D.L.7
  • 40
    • 73249116246 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 agonists protect pancreatic β-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB
    • Cunha DA, Ladriére L, Ortis F, Igoillo-Esteve M, Gurzov EN, Lupi R, Marchetti P, Eizirik DL, Cnop M 2009 Glucagon-like peptide-1 agonists protect pancreatic β-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. Diabetes 58: 2851-2862
    • (2009) Diabetes , vol.58 , pp. 2851-2862
    • Cunha, D.A.1    Ladriére, L.2    Ortis, F.3    Igoillo-Esteve, M.4    Gurzov, E.N.5    Lupi, R.6    Marchetti, P.7    Eizirik, D.L.8    Cnop, M.9
  • 43
    • 0029797603 scopus 로고    scopus 로고
    • Glucose promotes survival of rat pancreatic β cells by activating synthesis of proteins which suppress a constitutive apoptotic program
    • Hoorens A, Van de Casteele M, Klöppel G, Pipeleers D 1996 Glucose promotes survival of rat pancreatic β-cells by activating synthesis of proteins which suppress a constitutive apoptotic program. J Clin Invest 98:1568-1574 (Pubitemid 26327866)
    • (1996) Journal of Clinical Investigation , vol.98 , Issue.7 , pp. 1568-1574
    • Hoorens, A.1    De Van, C.M.2    Kloppel, G.3    Pipeleers, D.4
  • 44
    • 77749246118 scopus 로고    scopus 로고
    • Enhanced signaling downstream of ribonucleic acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets
    • Ladrière L, Igoillo-Esteve M, Cunha DA, Brion JP, Bugliani M, Marchetti P, Eizirik DL, Cnop M 2010 Enhanced signaling downstream of ribonucleic acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets. J Clin Endocrinol Metab 95:1442-1449
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1442-1449
    • Ladrière, L.1    Igoillo-Esteve, M.2    Cunha, D.A.3    Brion, J.P.4    Bugliani, M.5    Marchetti, P.6    Eizirik, D.L.7    Cnop, M.8
  • 45
    • 0035079807 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1β-exposed human and rat islet cells
    • DOI 10.1007/s001250051622
    • Chen MC, Proost P, Gysemans C, Mathieu C, Eizirik DL 2001 Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in IL-1β-exposed human and rat islet cells. Diabetologia 44:325-332 (Pubitemid 32234459)
    • (2001) Diabetologia , vol.44 , Issue.3 , pp. 325-332
    • Chen, M.-C.1    Proost, P.2    Gysemans, C.3    Mathieu, C.4    Eizirik, D.L.5
  • 46
    • 0033119065 scopus 로고    scopus 로고
    • Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR
    • DOI 10.1006/cyto.1998.0426
    • Overbergh L, Valckx D, Waer M, Mathieu C 1999 Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR. Cytokine 11:305-312 (Pubitemid 29213178)
    • (1999) Cytokine , vol.11 , Issue.4 , pp. 305-312
    • Overbergh, L.1    Valckx, D.2    Waer, M.3    Mathieu, C.4
  • 48
    • 33750577982 scopus 로고    scopus 로고
    • Nuclear factor-{kappa}B regulates β-cell death: A critical role for A20 in β-cell protection
    • DOI 10.2337/db06-0142
    • Liuwantara D, Elliot M, Smith MW, Yam AO, Walters SN, Marino E, McShea A, Grey ST 2006 Nuclear factor-κB regulates β-cell death: a critical role for A20 in β-cell protection. Diabetes 55:2491-2501 (Pubitemid 44871149)
    • (2006) Diabetes , vol.55 , Issue.9 , pp. 2491-2501
    • Liuwantara, D.1    Elliot, M.2    Smith, M.W.3    Yam, A.O.4    Walters, S.N.5    Marino, E.6    McShea, A.7    Grey, S.T.8
  • 49
    • 70350028224 scopus 로고    scopus 로고
    • Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: A novel mechanism for pancreatic β-cell apoptosis
    • Gurzov EN, Ortis F, Cunha DA, Gosset G, Li M, Cardozo AK, Eizirik DL 2009 Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis. Cell Death Differ 16:1539-1550
    • (2009) Cell Death Differ , vol.16 , pp. 1539-1550
    • Gurzov, E.N.1    Ortis, F.2    Cunha, D.A.3    Gosset, G.4    Li, M.5    Cardozo, A.K.6    Eizirik, D.L.7
  • 52
    • 0036179723 scopus 로고    scopus 로고
    • An immunohistochemical approach to monitor the prolactin-induced activation of the JAK2/STAT5 pathway in pancreatic islets of langerhans
    • Brelje TC, Svensson AM, Stout LE, Bhagroo NV, Sorenson RL 2002 An immunohistochemical approach to monitor the prolactin-induced activation of the JAK2/STAT5 pathway in pancreatic islets of Langerhans. J Histochem Cytochem 50:365-383 (Pubitemid 34171060)
    • (2002) Journal of Histochemistry and Cytochemistry , vol.50 , Issue.3 , pp. 365-383
    • Brelje, T.C.1    Svensson, A.M.2    Stout, L.E.3    Bhagroo, N.V.4    Sorenson, R.L.5
  • 53
    • 4344581494 scopus 로고    scopus 로고
    • Distinctive roles for prolactin and growth hormone in the activation of signal transducer and activator of transcription 5 in pancreatic islets of Langerhans
    • DOI 10.1210/en.2004-0201
    • Brelje TC, Stout LE, Bhagroo NV, Sorenson RL 2004 Distinctive roles for prolactin and growth hormone in the activation of signal transducer and activator of transcription 5 in pancreatic islets of Langerhans. Endocrinology 145:4162-4175 (Pubitemid 39120565)
    • (2004) Endocrinology , vol.145 , Issue.9 , pp. 4162-4175
    • Brelje, T.C.1    Stout, L.E.2    Bhagroo, N.V.3    Sorenson, R.L.4
  • 54
    • 4544371118 scopus 로고    scopus 로고
    • Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid differentiation
    • DOI 10.1084/jem.20041024
    • Schuringa JJ, Chung KY, Morrone G, Moore MA 2004 Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid differentiation. J Exp Med 200:623-635 (Pubitemid 39258311)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.5 , pp. 623-635
    • Schuringa, J.J.1    Chung, K.Y.2    Morrone, G.3    Moore, M.A.S.4
  • 55
    • 33846187999 scopus 로고    scopus 로고
    • STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas
    • DOI 10.1038/sj.onc.1209775, PII 1209775
    • Walker SR, Nelson EA, Frank DA 2007 STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas. Oncogene 26:224-233 (Pubitemid 46095733)
    • (2007) Oncogene , vol.26 , Issue.2 , pp. 224-233
    • Walker, S.R.1    Nelson, E.A.2    Frank, D.A.3
  • 57
    • 0020055353 scopus 로고
    • Effects of growth hormone, prolactin, and placental lactogen on insulin content and release, and deoxyribonucleic acid synthesis in cultured pancreatic islets
    • Nielsen JH 1982 Effects of growth hormone, prolactin, and placental lactogen on insulin content and release, and deoxyribonucleic acid synthesis in cultured pancreatic islets. Endocrinology 110:600-606 (Pubitemid 12162957)
    • (1982) Endocrinology , vol.110 , Issue.2 , pp. 600-606
    • Nielsen, J.H.1
  • 59
    • 63849201305 scopus 로고    scopus 로고
    • Prolactin receptors are critical to the adaptation of islets to pregnancy
    • Sorenson RL, Brelje TC 2009 Prolactin receptors are critical to the adaptation of islets to pregnancy. Endocrinology 150:1566-1569
    • (2009) Endocrinology , vol.150 , pp. 1566-1569
    • Sorenson, R.L.1    Brelje, T.C.2
  • 60
    • 0036374389 scopus 로고    scopus 로고
    • Prolactin modulation of immune and inflammatory responses
    • Yu-Lee LY 2002 Prolactin modulation of immune and inflammatory responses. Recent Prog Horm Res 57:435-455
    • (2002) Recent Prog Horm Res , vol.57 , pp. 435-455
    • Yu-Lee, L.Y.1
  • 61
    • 0032719397 scopus 로고    scopus 로고
    • Prolactin protects against diabetes induced by multiple low doses of streptozotocin in mice
    • Holstad M, Sandler S 1999 Prolactin protects against diabetes induced by multiple low doses of streptozotocin in mice. J Endocrinol 163:229-234
    • (1999) J Endocrinol , vol.163 , pp. 229-234
    • Holstad, M.1    Sandler, S.2
  • 65
    • 0037103133 scopus 로고    scopus 로고
    • Repression of AP-1 function: A mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene
    • Vasanwala FH, Kusam S, Toney LM, Dent AL 2002 Repression of AP-1 function: a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene. J Immunol 169:1922-1929 (Pubitemid 34857655)
    • (2002) Journal of Immunology , vol.169 , Issue.4 , pp. 1922-1929
    • Vasanwala, F.H.1    Kusam, S.2    Toney, L.M.3    Dent, A.L.4
  • 66
    • 77649326700 scopus 로고    scopus 로고
    • MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA
    • Colli ML, Moore F, Gurzov EN, Ortis F, Eizirik DL 2010 MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA. Hum Mol Genet 19:135-146
    • (2010) Hum Mol Genet , vol.19 , pp. 135-146
    • Colli, M.L.1    Moore, F.2    Gurzov, E.N.3    Ortis, F.4    Eizirik, D.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.