Endogenous nitric oxide and myocardial adaptation to ischemia

Circulation Research

Volumn 87, Issue 2, 2000, Pages 146-152

  Heusch, Gerd ^a   Post, Heiner ^a   Michel, Martin C ^a   Kelm, Malte ^b   Schulz, Rainer ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Contractile function; Ischemia; Oxygen consumption

Indexed keywords

NITRIC OXIDE;

ANIMAL TISSUE; ARTICLE; CORONARY ARTERY BLOOD FLOW; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MYOCARDIAL HIBERNATION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

EID: 0034698063     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.87.2.146     Document Type: Article

References (33)

1. A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina
2. Hibernating myocardium
3. Myocardial perfusion-contraction matching: Implications for coronary heart disease and hibernation
4. Calcium responsiveness in regional myocardial short-term hibernation and stunning in the in situ porcine heart: Inotropic responses to postextrasystolic potentiation and intracoronary calcium
5. The L-arginine-nitric oxide pathway
6. The nitric oxide hypothesis of late preconditioning
7. Activation of nitric oxide synthase by ischaemia in the perfused heart
8. Role of nitric oxide in regulation of coronary blood flow during myocardial ischemia in dogs
9. Nitric oxide does not modulate myocardial contractility acutely in in situ canine hearts
10. Blockade of nitric oxide synthesis reduces myocardial oxygen consumption in vivo
11. Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide
12. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide
13. Role of endothelium-derived nitric oxide in the modulation of canine myocardial mitochondrial respiration in vitro: Implications for the development of heart failure
14. Nitric oxide: An important signaling mechanism between vascular endothelium and parenchymal cells in the regulation of oxygen consumption
15. Function and production of nitric oxide in the coronary circulation of the conscious dog during exercise
16. Nitric oxide controls cardiac substrate utilization in the conscious dog
17. Inorganic phosphate content and free energy change of ATP hydrolysis in regional short-term hibernating myocardium
18. Identification of necrotic tissue by phase-contrast microscopy at an early stage of acute myocardial infarction
19. - in aqueous and protein-containing samples
20. Significance of regional wall thickening abnormalities relative to transmural myocardial perfusion in anesthetized dogs
21. No effect of coronary perfusion on regional myocardial function within the autoregulatory range in pigs: Evidence against the Gregg phenomenon
22. Lack of correlation between myocardial nitric oxide and cyclic guanosine monophosphate content in both nitrate-tolerant and -nontolerant rats
23. Cardiovascular actions of inhibitors of endothelium-derived relaxing factor (nitric oxide) formation/release in anesthetized dogs
24. Role of nitric oxide in the regulation of oxygen consumption in conscious dogs
25. Low increase in cPGM induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes
26. Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes
27. 2 consumption in experimental left ventricular hypertrophy: Effect of negative inotropes
28. 2 consumption in the nonhuman primate: An additional mechanism of action of amlodipine
29. Nitric oxide modulates mitochondrial respiration in failing human heart
30. 2+ transient that follow stretch of cardiac muscle: A possible explanation of the anrep effect
31. The role of calcium in the response of cardiac muscle to stretch
32. 2+ sensitization predominantly enhances function and mechanical efficiency of stunned myocardium
33. Improved mechanoenergetics and cardiac rest and reserve function of in vivo failing heart by calcium sensitizer EMD-57033