Insulin inhibits leukocyte-endothelium adherence via an Akt-NO-dependent mechanism in myocardial ischemia/reperfusion

Journal of Molecular and Cellular Cardiology

Volumn 47, Issue 4, 2009, Pages 512-519

  Li, Jia ^a   Wu, Feng ^b   Zhang, Haifeng ^a   Fu, Feng ^a   Ji, Lele ^a   Dong, Ling ^a   Li, Qiuxia ^a   Liu, Wenchong ^a   Zhang, Yuan ^a   Lv, Anlin ^a   Wang, Haichang ^a   Ren, Jun ^c   Gao, Feng ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b Department of Cardiology   (China)

^c UNIVERSITY OF WYOMING   (United States)

Author keywords

Akt; Endothelial cells; Insulin; Myocardial ischemia reperfusion; Polymorphonuclear leukocytes

Indexed keywords

CAVTRATIN; CREATINE KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PADGEM PROTEIN; POTASSIUM; PROTEIN KINASE B; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTERY ENDOTHELIUM; ARTICLE; CELL ADHESION; CELL STIMULATION; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

ANIMALS; BLOOD GLUCOSE; CELL ADHESION; CELL MEMBRANE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INSULIN; INTERCELLULAR ADHESION MOLECULE-1; MYOCARDIAL REPERFUSION INJURY; NEUTROPHILS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; P-SELECTIN; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RABBITS;

ORYCTOLAGUS CUNICULUS;

EID: 69249232079     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.07.010     Document Type: Article

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