메뉴 건너뛰기




Volumn 36, Issue 5, 2008, Pages 1551-1558

Insulin inhibits tumor necrosis factor-α induction in myocardial ischemia/reperfusion: Role of Akt and endothelial nitric oxide synthase phosphorylation

Author keywords

Akt; Inflammation; Insulin; Myocardial ischemia reperfusion; Nitric oxide; Tumor necrosis factor

Indexed keywords

CREATINE KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; IMMUNOGLOBULIN G; INSULIN; MYELOPEROXIDASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; POTASSIUM; PROTEIN KINASE B; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; WORTMANNIN;

EID: 42949103597     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181782335     Document Type: Article
Times cited : (76)

References (40)
  • 1
    • 0035829852 scopus 로고    scopus 로고
    • Intensive insulin therapy in critically ill patients
    • G Van den Berghe P Wouters F Weekers Intensive insulin therapy in critically ill patients N Engl J Med 345 2001 1359 1367
    • (2001) N Engl J Med , vol.345 , pp. 1359-1367
    • Van den Berghe, G1    Wouters, P2    Weekers, F3
  • 2
    • 0036705908 scopus 로고    scopus 로고
    • Insulin attenuates the systemic inflammatory response to thermal trauma
    • MG Jeschke R Einspanier D Klein Insulin attenuates the systemic inflammatory response to thermal trauma Mol Med 8 2002 443 450
    • (2002) Mol Med , vol.8 , pp. 443-450
    • Jeschke, MG1    Einspanier, R2    Klein, D3
  • 3
    • 33646556651 scopus 로고    scopus 로고
    • Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: role of glycogen synthase kinase-3beta inhibition
    • L Dugo M Collin DA Allen Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: role of glycogen synthase kinase-3beta inhibition Crit Care Med 34 2006 1489 1496
    • (2006) Crit Care Med , vol.34 , pp. 1489-1496
    • Dugo, L1    Collin, M2    Allen, DA3
  • 4
    • 10744232591 scopus 로고    scopus 로고
    • Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction
    • A Chaudhuri D Janicke MF Wilson Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction Circulation 109 2004 849 854
    • (2004) Circulation , vol.109 , pp. 849-854
    • Chaudhuri, A1    Janicke, D2    Wilson, MF3
  • 5
    • 0036597085 scopus 로고    scopus 로고
    • The anti-inflammatory and potential anti-atherogenic effect of insulin: A new paradigm
    • P Dandona A Aljada P Mohanty The anti-inflammatory and potential anti-atherogenic effect of insulin: A new paradigm Diabetologia 45 2002 924 930
    • (2002) Diabetologia , vol.45 , pp. 924-930
    • Dandona, P1    Aljada, A2    Mohanty, P3
  • 6
    • 0029900295 scopus 로고    scopus 로고
    • The tumor necrosis factor ligand and receptor families
    • F Bazzoni B Beutler The tumor necrosis factor ligand and receptor families N Engl J Med 334 1996 1717 1725
    • (1996) N Engl J Med , vol.334 , pp. 1717-1725
    • Bazzoni, F1    Beutler, B2
  • 7
    • 0025286817 scopus 로고
    • Elevated circulating levels of tumor necrosis factor in congestive heart failure
    • B Levine J Kalman L Mayer Elevated circulating levels of tumor necrosis factor in congestive heart failure N Engl J Med 323 1990 236 241
    • (1990) N Engl J Med , vol.323 , pp. 236-241
    • Levine, B1    Kalman, J2    Mayer, L3
  • 8
    • 0032805207 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function
    • BS Cain DR Meldrum CA Dinarello Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function Crit Care Med 27 1999 1309 1318
    • (1999) Crit Care Med , vol.27 , pp. 1309-1318
    • Cain, BS1    Meldrum, DR2    Dinarello, CA3
  • 9
    • 0033596949 scopus 로고    scopus 로고
    • Tissue expression and immunolocalization of tumor necrosis factor-α in postinfarction dysfunctional myocardium
    • MW Irwin S Mak DL Mann Tissue expression and immunolocalization of tumor necrosis factor-α in postinfarction dysfunctional myocardium Circulation 99 1999 1492 1498
    • (1999) Circulation , vol.99 , pp. 1492-1498
    • Irwin, MW1    Mak, S2    Mann, DL3
  • 10
    • 0027396266 scopus 로고
    • Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium
    • XL Ma AS Weyrich DJ Lefer Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium Circ Res 72 1993 403 412
    • (1993) Circ Res , vol.72 , pp. 403-412
    • Ma, XL1    Weyrich, AS2    Lefer, DJ3
  • 11
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation: Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • R De Caterina P Libby HB Peng Nitric oxide decreases cytokine-induced endothelial activation: Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines J Clin Invest 96 1995 60 68
    • (1995) J Clin Invest , vol.96 , pp. 60-68
    • De Caterina, R1    Libby, P2    Peng, HB3
  • 12
    • 0035161341 scopus 로고    scopus 로고
    • Nitric oxide: Does it play a role in the heart of the critically ill?
    • PB Massion S Moniotte JL Balligand Nitric oxide: Does it play a role in the heart of the critically ill? Curr Opin Crit Care 7 2001 323 336
    • (2001) Curr Opin Crit Care , vol.7 , pp. 323-336
    • Massion, PB1    Moniotte, S2    Balligand, JL3
  • 13
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • G Zeng FH Nystrom LV Ravichandran Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells Circulation 101 2000 1539 1545
    • (2000) Circulation , vol.101 , pp. 1539-1545
    • Zeng, G1    Nystrom, FH2    Ravichandran, LV3
  • 14
    • 0037177142 scopus 로고    scopus 로고
    • Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia/reperfusion: The roles of PI3-Kinase, Akt, and endothelial nitric oxide synthase phosphorylation
    • F Gao E Gao TL Yue Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia/reperfusion: The roles of PI3-Kinase, Akt, and endothelial nitric oxide synthase phosphorylation Circulation 105 2002 1497 1502
    • (2002) Circulation , vol.105 , pp. 1497-1502
    • Gao, F1    Gao, E2    Yue, TL3
  • 15
    • 3042702881 scopus 로고    scopus 로고
    • Inflammatory cytokines and postmyocardial infarction remodeling
    • M Nian P Lee N Khaper Inflammatory cytokines and postmyocardial infarction remodeling Circ Res 94 2004 1543 1553
    • (2004) Circ Res , vol.94 , pp. 1543-1553
    • Nian, M1    Lee, P2    Khaper, N3
  • 16
    • 85047676410 scopus 로고
    • Myocardial metabolic and morphometric changes during canine endotoxin shock before and after glucose-insulin-potassium
    • W Bronsveld AA van Lambalgen D van Velzen Myocardial metabolic and morphometric changes during canine endotoxin shock before and after glucose-insulin-potassium Cardiovasc Res 19 1985 455 464
    • (1985) Cardiovasc Res , vol.19 , pp. 455-464
    • Bronsveld, W1    van Lambalgen, AA2    van Velzen, D3
  • 17
    • 0032894044 scopus 로고    scopus 로고
    • Glucose potassium insulin infusions in the treatment of acute stroke patients with mild to moderate hyperglycemia: The Glucose Insulin in Stroke Trial (GIST)
    • JF Scott GM Robinson JM French Glucose potassium insulin infusions in the treatment of acute stroke patients with mild to moderate hyperglycemia: The Glucose Insulin in Stroke Trial (GIST) Stroke 30 1999 793 799
    • (1999) Stroke , vol.30 , pp. 793-799
    • Scott, JF1    Robinson, GM2    French, JM3
  • 19
    • 0035824907 scopus 로고    scopus 로고
    • Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling
    • AK Jonassen MN Sack OD Mjos Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling Circ Res 89 2001 1191 1198
    • (2001) Circ Res , vol.89 , pp. 1191-1198
    • Jonassen, AK1    Sack, MN2    Mjos, OD3
  • 20
    • 0014077032 scopus 로고
    • An improved procedure for serum creatine phosphokinase determination
    • SM Rosalki An improved procedure for serum creatine phosphokinase determination J Lab Clin Med 69 1967 969 970
    • (1967) J Lab Clin Med , vol.69 , pp. 969-970
    • Rosalki, SM1
  • 21
    • 0036164426 scopus 로고    scopus 로고
    • p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation
    • F Gao TL Yue DW Shi p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation Cardiovasc Res 53 2002 414 422
    • (2002) Cardiovasc Res , vol.53 , pp. 414-422
    • Gao, F1    Yue, TL2    Shi, DW3
  • 22
    • 34548407280 scopus 로고    scopus 로고
    • Acute hyperglycemia exacerbates myocardial ischemia/reperfusion injury and blunts cardioprotective effect of GIK
    • H Su X Sun H Ma Acute hyperglycemia exacerbates myocardial ischemia/reperfusion injury and blunts cardioprotective effect of GIK Am J Physiol Endocrinol Metab 293 2007 E629 E635
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. E629-E635
    • Su, H1    Sun, X2    Ma, H3
  • 23
    • 0034737730 scopus 로고    scopus 로고
    • Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart
    • TL Yue C Wang JL Gu Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart Circ Res 86 2000 692 699
    • (2000) Circ Res , vol.86 , pp. 692-699
    • Yue, TL1    Wang, C2    Gu, JL3
  • 24
    • 29144477288 scopus 로고    scopus 로고
    • Vasculoprotective effect of insulin in the ischemic/reperfused canine heart: Role of Akt-stimulated NO production
    • H Ma HF Zhang L Yu Vasculoprotective effect of insulin in the ischemic/reperfused canine heart: Role of Akt-stimulated NO production Cardiovasc Res 69 2006 57 65
    • (2006) Cardiovasc Res , vol.69 , pp. 57-65
    • Ma, H1    Zhang, HF2    Yu, L3
  • 25
    • 0025910124 scopus 로고
    • NADH measurements in adult rat myocytes during simulated ischemia
    • K Esumi M Nishida D Shaw NADH measurements in adult rat myocytes during simulated ischemia Am J Physiol 260 1991 H1743 H1752
    • (1991) Am J Physiol , vol.260 , pp. H1743-H1752
    • Esumi, K1    Nishida, M2    Shaw, D3
  • 26
    • 33846444724 scopus 로고    scopus 로고
    • Acute effects of hyperglycemia and hyperinsulinemia on hepatic oxidative stress and the systemic inflammatory response in rats
    • PR Ling RJ Smith BR Bistrian Acute effects of hyperglycemia and hyperinsulinemia on hepatic oxidative stress and the systemic inflammatory response in rats Crit Care Med 35 2007 555 560
    • (2007) Crit Care Med , vol.35 , pp. 555-560
    • Ling, PR1    Smith, RJ2    Bistrian, BR3
  • 27
    • 18844445117 scopus 로고    scopus 로고
    • A challenge to the metabolic approach to myocardial ischaemia
    • CS Apstein LH Opie A challenge to the metabolic approach to myocardial ischaemia Eur Heart J 26 2005 956 959
    • (2005) Eur Heart J , vol.26 , pp. 956-959
    • Apstein, CS1    Opie, LH2
  • 28
    • 18844461232 scopus 로고    scopus 로고
    • p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart
    • M Li D Georgakopoulos G Lu p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart Circulation 111 2005 2494 2502
    • (2005) Circulation , vol.111 , pp. 2494-2502
    • Li, M1    Georgakopoulos, D2    Lu, G3
  • 29
    • 29144522171 scopus 로고    scopus 로고
    • Nitric oxide donors alter cardiomyocyte cytokine secretion and cardiac function
    • DL Maass J White JW Horton Nitric oxide donors alter cardiomyocyte cytokine secretion and cardiac function Crit Care Med 33 2005 2794 2803
    • (2005) Crit Care Med , vol.33 , pp. 2794-2803
    • Maass, DL1    White, J2    Horton, JW3
  • 30
    • 0030689717 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha improves myocardial recovery after ischemia and reperfusion
    • J Gurevitch I Frolkis Y Yuhas Anti-tumor necrosis factor-alpha improves myocardial recovery after ischemia and reperfusion J Am Coll Cardiol 30 1997 1554 1561
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1554-1561
    • Gurevitch, J1    Frolkis, I2    Yuhas, Y3
  • 31
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
    • P Dandona A Aljada P Mohanty Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 86 2001 3257 3265
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3257-3265
    • Dandona, P1    Aljada, A2    Mohanty, P3
  • 32
    • 0037199972 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
    • M Guha N Mackman The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells J Biol Chem 277 2002 32124 32132
    • (2002) J Biol Chem , vol.277 , pp. 32124-32132
    • Guha, M1    Mackman, N2
  • 33
    • 0033055969 scopus 로고    scopus 로고
    • Involvement of both the tyrosine kinase and the phosphatidylinositol-3′ kinase signal transduction pathways in the regulation of lipoprotein lipase expression in J774.2 macrophages by cytokines and lipopolysaccharide
    • TS Tengku-Muhammad TR Hughes A Cryer Involvement of both the tyrosine kinase and the phosphatidylinositol-3′ kinase signal transduction pathways in the regulation of lipoprotein lipase expression in J774.2 macrophages by cytokines and lipopolysaccharide Cytokine 11 1999 463 468
    • (1999) Cytokine , vol.11 , pp. 463-468
    • Tengku-Muhammad, TS1    Hughes, TR2    Cryer, A3
  • 34
    • 0036368598 scopus 로고    scopus 로고
    • Angiopoietin-1 negatively regulates expression and activity of tissue factor in endothelial cells
    • I Kim JL Oh YS Ryu Angiopoietin-1 negatively regulates expression and activity of tissue factor in endothelial cells FASEB J 16 2002 126 128
    • (2002) FASEB J , vol.16 , pp. 126-128
    • Kim, I1    Oh, JL2    Ryu, YS3
  • 35
    • 0037304922 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase: The Cinderella of inflammation?
    • G Cirino S Fiorucci WC Sessa Endothelial nitric oxide synthase: The Cinderella of inflammation? Trends Pharmacol Sci 24 2003 91 95
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 91-95
    • Cirino, G1    Fiorucci, S2    Sessa, WC3
  • 36
    • 2442636658 scopus 로고    scopus 로고
    • Up-regulation of endothelial nitric oxide synthase inhibits pulmonary leukocyte migration following lung ischemia-reperfusion in mice
    • A Kaminski CB Pohl C Sponholz Up-regulation of endothelial nitric oxide synthase inhibits pulmonary leukocyte migration following lung ischemia-reperfusion in mice Am J Pathol 164 2004 2241 2249
    • (2004) Am J Pathol , vol.164 , pp. 2241-2249
    • Kaminski, A1    Pohl, CB2    Sponholz, C3
  • 37
    • 0034603545 scopus 로고    scopus 로고
    • Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: A systematic overview
    • SE Capes D Hunt K Malmberg Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: A systematic overview Lancet 355 2000 773 778
    • (2000) Lancet , vol.355 , pp. 773-778
    • Capes, SE1    Hunt, D2    Malmberg, K3
  • 38
    • 12544259347 scopus 로고    scopus 로고
    • Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: The CREATE-ECLA randomized controlled trial
    • SR Mehta S Yusuf R Diaz Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: The CREATE-ECLA randomized controlled trial JAMA 293 2005 437 446
    • (2005) JAMA , vol.293 , pp. 437-446
    • Mehta, SR1    Yusuf, S2    Diaz, R3
  • 39
    • 0037109184 scopus 로고    scopus 로고
    • Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans
    • K Esposito F Nappo R Marfella Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans Circulation 106 2002 2067 2072
    • (2002) Circulation , vol.106 , pp. 2067-2072
    • Esposito, K1    Nappo, F2    Marfella, R3
  • 40
    • 0037326620 scopus 로고    scopus 로고
    • Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control
    • G Van den Berghe PJ Wouters R Bouillon Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control Crit Care Med 31 2003 359 366
    • (2003) Crit Care Med , vol.31 , pp. 359-366
    • Van den Berghe, G1    Wouters, PJ2    Bouillon, R3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.