The 1.5-Å structure of Chryseobacterium meningosepticum zinc β-lactamase in complex with the inhibitor, D-captopril

Journal of Biological Chemistry

Volumn 278, Issue 26, 2003, Pages 23868-23873

  García Sáez, Isabel ^a   Hopkins, Julie ^a   Papamicael, Cyril ^b   Franceschini, Nicola ^c   Amicosante, Gianfranco ^c   Rossolinill, Gian Maria ^d   Galleni, Moreno ^e   Frère, Jean Marie ^e   Dideberg, Otto ^a  

^a CEA GRENOBLE   (France)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d UNIVERSITY OF SIENA   (Italy)

^e UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; DRUG PRODUCTS; ENZYME INHIBITION; HYDROLYSIS; MOLECULES; POSITIVE IONS; ZINC;

DIASTEREOISOMERS;

BACTERIA;

BACTERIAL ENZYME; CAPTOPRIL; METAL; UNCLASSIFIED DRUG; ZINC BETA LACTAMASE; ZINC ION; BACTERIAL PROTEIN; BETA LACTAMASE; ENZYME INHIBITOR; ZINC;

ARTICLE; BINDING SITE; CHRYSEOBACTERIUM; CHRYSEOBACTERIUM MENINGOSEPTICUM; COMPLEX FORMATION; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME STRUCTURE; HYDROLYSIS; METAL BINDING; NONHUMAN; OPTICAL RESOLUTION; PRIORITY JOURNAL; STEREOISOMERISM; X RAY ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; FLAVOBACTERIUM; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); CHRYSEOBACTERIUM; CHRYSEOBACTERIUM MENINGOSEPTICUM; NEGIBACTERIA;

BACTERIAL PROTEINS; BETA-LACTAMASES; BINDING SITES; CAPTOPRIL; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FLAVOBACTERIUM; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN CONFORMATION; ZINC;

EID: 0037592222     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301062200     Document Type: Article

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