Alx3-deficient mice exhibit decreased insulin in beta cells, altered glucose homeostasis and increased apoptosis in pancreatic islets

Diabetologia

Volumn 54, Issue 2, 2011, Pages 403-414

  Mirasierra, M ^a   Fernandez Perez A ^a   Diaz Prieto N ^a   Vallejo, M ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Apoptosis; Aristaless; Glucagon; Glucokinase; Homeodomain; Insulin resistance; Insulin secretion; Transcription

Indexed keywords

GLUCAGON; GLUCOKINASE; GLUCOSE; INSULIN; INSULIN RECEPTOR; PROTEIN KINASE B;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARISTALESS LIKE HOMEOBOX 3 GENE; ARTICLE; CELL SIZE; CONTROLLED STUDY; DIABETES MELLITUS; GCK GENE; GENE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUT2 GENE; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE; HOMEODOMAIN PROTEINS; HOMEOSTASIS; IN SITU NICK-END LABELING; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MICE, MUTANT STRAINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78951478527     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1975-6     Document Type: Article

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