-
3
-
-
3843090515
-
β-cell lipotoxicity: Burning fat into heat?
-
Poitout V. β-cell lipotoxicity: Burning fat into heat? Endocrinology 2004; 145:3563-5.
-
(2004)
Endocrinology
, vol.145
, pp. 3563-3565
-
-
Poitout, V.1
-
4
-
-
0035145780
-
Lipotoxicity of the pancreatic β-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids
-
Briaud I, Harmon JS, Kelpe CL, Segu VBG, Poitout V. Lipotoxicity of the pancreatic β-cell is associated with glucose-dependent esterification of fatty acid into neutral lipids. Diabetes 2001; 50:315-23. (Pubitemid 32127288)
-
(2001)
Diabetes
, vol.50
, Issue.2
, pp. 315-321
-
-
Briaud, I.1
Harmon, J.S.2
Kelpe, C.L.3
Segu, V.B.G.4
Poitout, V.5
-
5
-
-
0036217052
-
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
-
DOI 10.1210/er.23.2.201
-
Lewis GF, Carpentier A, Khospow A, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocrine Review 2002; 23:201-29. (Pubitemid 34299024)
-
(2002)
Endocrine Reviews
, vol.23
, Issue.2
, pp. 201-229
-
-
Lewis, G.F.1
Carpentier, A.2
Adeli, K.3
Giacca, A.4
-
6
-
-
0035130102
-
Diseases of liporegulation: New perspective on obesity and related disorders
-
Unger RH, Orci L. Diseases of liporegulation: New perspective on obesity and related disorders. FASEB J 2001; 15:312-21.
-
(2001)
FASEB J
, vol.15
, pp. 312-321
-
-
Unger, R.H.1
Orci, L.2
-
7
-
-
28844485678
-
Effects of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans. A Review
-
Lombardo YB, Chicco A. Effects of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans. A Review. J Nutr Biochem 2006; 17:1-13.
-
(2006)
J Nutr Biochem
, vol.17
, pp. 1-13
-
-
Lombardo, Y.B.1
Chicco, A.2
-
8
-
-
0037224527
-
Muscle lipid metabolism and insulin secretion are altered in insulin-resistant rats fed a high sucrose diet
-
Chicco A, D'Alessandro ME, Karabatas L, Pastorale C, Basabe JC, Lombardo YB. Muscle lipid metabolism and insulin secretion are altered in insulin-resistant rats fed a high sucrose diet. J Nutr 2003; 133:127-33.
-
(2003)
J Nutr
, vol.133
, pp. 127-133
-
-
Chicco, A.1
D'Alessandro, M.E.2
Karabatas, L.3
Pastorale, C.4
Basabe, J.C.5
Lombardo, Y.B.6
-
9
-
-
0032699259
-
Fatty acid inhibition of glucose stimulated insulin secretion is enhanced in pancreatic islets from insulin-resistant rats
-
Chen NG, Reaven GM. Fatty acid inhibition of glucose stimulated insulin secretion is enhanced in pancreatic islets from insulin-resistant rats. Metabolism 1999; 48:1314-7.
-
(1999)
Metabolism
, vol.48
, pp. 1314-1317
-
-
Chen, N.G.1
Reaven, G.M.2
-
10
-
-
67449136331
-
Islet adaptative changes to fructose- induced insulin resistance: β-cell mass, glucokinase, glucose metabolism and insulin secretion
-
Maiztegui B, Borelli MI, Raschia MA, Del Zotto H, Gagliardino JJ. Islet adaptative changes to fructose- induced insulin resistance: β-cell mass, glucokinase, glucose metabolism and insulin secretion. J of Endocrinol 2009; 200:139-49.
-
(2009)
J of Endocrinol
, vol.200
, pp. 139-149
-
-
Maiztegui, B.1
Borelli, M.I.2
Raschia, M.A.3
Del Zotto, H.4
Gagliardino, J.J.5
-
11
-
-
0344738796
-
Fish oil affects pancreatic fat storage, pyruvate dehydrogenase complex activity and insulin secretion in rats fed a sucrose-rich diet
-
Pighin D, Karabatas L, Rossi A, Chicco A, Basabe JC, Lombardo YB. Fish oil affects pancreatic fat storage, pyruvate dehydrogenase complex activity and insulin secretion in rats fed a sucrose-rich diet. J Nutrition 2003; 133:4095-101.
-
(2003)
J Nutrition
, vol.133
, pp. 4095-4101
-
-
Pighin, D.1
Karabatas, L.2
Rossi, A.3
Chicco, A.4
Basabe, J.C.5
Lombardo, Y.B.6
-
12
-
-
0032452225
-
Regulatory interactions between lipids and carbohydrates: The glucose fatty acid cycle after 35 years
-
Randle PJ. Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years. Diabetes Metab Rev 1998; 14:363-83.
-
(1998)
Diabetes Metab Rev
, vol.14
, pp. 363-383
-
-
Randle, P.J.1
-
13
-
-
0029983884
-
A fatty acid-induced decrease in pyruvate dehydrogenase activity is an important determinant of β-cell dysfunction in the obese diabetic db/db mouse
-
Zhou YP, Berggren PO, Grill V. A fatty acid-induced decrease in pyruvate dehydrogenase activity is an important determinant of β-cell dysfunction in the obese diabetic db/db mouse. Diabetes 1996; 45:580-6.
-
(1996)
Diabetes
, vol.45
, pp. 580-586
-
-
Zhou, Y.P.1
Berggren, P.O.2
Grill, V.3
-
14
-
-
0023595212
-
Long-term hypertriglyceridemia and glucose intolerance in rats fed chronically an isocaloric sucrose-rich diet
-
Gutman RA, Basilico MZ, Bernal C, Chicco A, Lombardo YB. Long-term hypertriglyceridemia and glucose intolerance in rats fed chronically an isocaloric sucrose-rich diet. Metabolism 1987; 36:1013-20.
-
(1987)
Metabolism
, vol.36
, pp. 1013-1020
-
-
Gutman, R.A.1
Basilico, M.Z.2
Bernal, C.3
Chicco, A.4
Lombardo, Y.B.5
-
15
-
-
0030447114
-
Long term administration of a sucrose-rich diet to normal rats: Relationship between metabolic and hormonal profiles and morphological changes in the endocrine pancreas
-
Lombardo YB, Drago S, Chicco A, Fainstein-Day P, Gutman R, Gagliardino JJ, et al. Long term administration of a sucrose-rich diet to normal rats: relationship between metabolic and hormonal profiles and morphological changes in the endocrine pancreas. Metabolism 1996; 46:1527-32.
-
(1996)
Metabolism
, vol.46
, pp. 1527-1532
-
-
Lombardo, Y.B.1
Drago, S.2
Chicco, A.3
Fainstein-Day, P.4
Gutman, R.5
Gagliardino, J.J.6
-
16
-
-
33745863033
-
Islet β cell failure in type 2 diabetes
-
DOI 10.1172/JCI29103
-
Prentki M, Nolan CJ. Islet β-cell failure in type 2 diabetes. J Clin Invest 2006; 116:1802-12. (Pubitemid 44033300)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
17
-
-
0030067124
-
Banting Lecture 1995: A lesson in metabolic regulation inspired by glucokinase sensor paradigm
-
Matschinsky FM. Banting Lecture 1995: A lesson in metabolic regulation inspired by glucokinase sensor paradigm. Diabetes 1996; 45:223-41.
-
(1996)
Diabetes
, vol.45
, pp. 223-241
-
-
Matschinsky, F.M.1
-
18
-
-
0028338940
-
Mechanism of compensatory hyperinsulinemia in normoglycemic insulin-resistant spontaneously hypertensive rats. Augmented enzymatic activity of glucokinase in β-cells
-
Chen C, Hosokawa H, Bumbalo LM, Leahy JC. Mechanism of compensatory hyperinsulinemia in normoglycemic insulin-resistant spontaneously hypertensive rats. Augmented enzymatic activity of glucokinase in β-cells. J Clin Invest 1994; 94:399-404.
-
(1994)
J Clin Invest
, vol.94
, pp. 399-404
-
-
Chen, C.1
Hosokawa, H.2
Bumbalo, L.M.3
Leahy, J.C.4
-
19
-
-
0028198490
-
Increased catalytic activity of glucokinase in isolated islets from hyperinsulinemic rats
-
Chen C, Bumbalo L, Leahy JC. Increased activity of glucokinase in isolated islets from hyperinsulinemic rats. Diabetes 1994; 43:684-9. (Pubitemid 24138782)
-
(1994)
Diabetes
, vol.43
, Issue.5
, pp. 684-689
-
-
Chen, C.1
Bumbalo, L.2
Leahy, J.L.3
-
20
-
-
0027482029
-
Glucokinase activity in isolated islets from obese fa/fa Zucker rats
-
Chan CB. Glucokinase activity in isolated islets from obese fa/fa Zucker rats. Biochem J 1993; 295:673-7.
-
(1993)
Biochem J
, vol.295
, pp. 673-677
-
-
Chan, C.B.1
-
21
-
-
33846024011
-
Glucokinase and IRS-2 are required for compensatory β cell hyperplasia in response to high-fat diet-induced insulin resistance
-
Terauchi Y, Takamoto I, Kubota N, Matsui J, Suzuki R, Komeda K, et al. Glucokinase and IRS-2 are required for compensatory β cell hyperplasia in response to high-fat diet-induced insulin resistance. J Clin Invest 2007; 117:246-57.
-
(2007)
J Clin Invest
, vol.117
, pp. 246-257
-
-
Terauchi, Y.1
Takamoto, I.2
Kubota, N.3
Matsui, J.4
Suzuki, R.5
Komeda, K.6
-
23
-
-
0842263985
-
Role of peroxisomal proliferator-activated receptor gamma in the glucose-sensing apparatus of liver and β-cells
-
Kim H, Ahn Y. Role of peroxisomal proliferator-activated receptor gamma in the glucose-sensing apparatus of liver and β-cells. Diabetes 2004; 60-5.
-
(2004)
Diabetes
, pp. 60-65
-
-
Kim, H.1
Ahn, Y.2
-
24
-
-
33845517309
-
Fatty acid signaling in the β-cell and insulin secretion
-
Nolan CJ, Madiraju MSRE, Delghingaro-Augusto V, Peyot ML, Prentki M. Fatty acid signaling in the β-cell and insulin secretion. Diabetes 2006; 55:16-23.
-
(2006)
Diabetes
, vol.55
, pp. 16-23
-
-
Nolan, C.J.1
Madiraju, M.S.R.E.2
Delghingaro-Augusto, V.3
Peyot, M.L.4
Prentki, M.5
-
25
-
-
0036153256
-
Minireview: Secondary β-cell failure in type 2 diabetes. A consequence of glucotoxicity and lipotoxicity
-
Poitout V, Robertson RP. Minireview: Secondary β-cell failure in type 2 diabetes. A consequence of glucotoxicity and lipotoxicity. Endocrinology 2002; 143:339-42.
-
(2002)
Endocrinology
, vol.143
, pp. 339-342
-
-
Poitout, V.1
Robertson, R.P.2
-
26
-
-
23844490919
-
High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction
-
Kooptiwut S, Kebede M, Zraika S, Visioni S, Aston-Mourney K, Favaloro J, et al. High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction. J Mol Endocrinol 2005; 35:39-48.
-
(2005)
J Mol Endocrinol
, vol.35
, pp. 39-48
-
-
Kooptiwut, S.1
Kebede, M.2
Zraika, S.3
Visioni, S.4
Aston-Mourney, K.5
Favaloro, J.6
-
27
-
-
0034072962
-
Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: A direct metformin effect on pancreatic beta-cells
-
Patane G, Piro S, Rabuazzo AM, Anello M, Vigneri B, Purello F. Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells. Diabetes 2000; 49:735-40.
-
(2000)
Diabetes
, vol.49
, pp. 735-740
-
-
Patane, G.1
Piro, S.2
Rabuazzo, A.M.3
Anello, M.4
Vigneri, B.5
Purello, F.6
-
28
-
-
0036896505
-
Malonyl- CoA signaling, lipid partitioning and glucolipotoxicity. Role in β-cell adaptation and failure in the etiology of diabetes
-
Prentki M, Joly E, El Assad W, Roduit R. Malonyl- CoA signaling, lipid partitioning and glucolipotoxicity. Role in β-cell adaptation and failure in the etiology of diabetes. Diabetes 2002; 51:405-13.
-
(2002)
Diabetes
, vol.51
, pp. 405-413
-
-
Prentki, M.1
Joly, E.2
El Assad, W.3
Roduit, R.4
-
29
-
-
0842327999
-
Chronic effects of fatty acids on pancreatic β-cell function. New insights from functional genomics
-
Biden TJ, Robinson D, Cordery D, Hughes W, Busch AK. Chronic effects of fatty acids on pancreatic β-cell function. New insights from functional genomics. Diabetes 2004; 53:159-65.
-
(2004)
Diabetes
, vol.53
, pp. 159-165
-
-
Biden, T.J.1
Robinson, D.2
Cordery, D.3
Hughes, W.4
Busch, A.K.5
-
30
-
-
0036724133
-
Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisomal proliferators-activated receptor γ inhibition
-
Patane G, Anello M, Piro S, Vigner R, Purello F, Rabuazzo AM. Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisomal proliferators-activated receptor γ inhibition. Diabetes 2002; 51:2749-56.
-
(2002)
Diabetes
, vol.51
, pp. 2749-2756
-
-
Patane, G.1
Anello, M.2
Piro, S.3
Vigner, R.4
Purello, F.5
Rabuazzo, A.M.6
-
31
-
-
0346340042
-
Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction
-
DOI 10.1172/JCI200319774
-
Krauss S, Zhang CY, Scorrano L, Dalgaard LF, Pierre JS, Grey ST, et al. Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β-cell dysfunction. J Clin Invest 2003; 112:1831-42. (Pubitemid 38063706)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1831-1842
-
-
Krauss, S.1
Zhang, C.-Y.2
Scorrano, L.3
Dalgaard, L.T.4
St-Pierre, J.5
Grey, S.T.6
Lowell, B.B.7
-
32
-
-
0025083434
-
Glucose regulates glucokinase activity in cultured islets from rat pancreas
-
Liang Y, Najafi H, Matschinsky FM. Glucose regulates glucokinase activity in cultured islets from rat pancreas. J Biol Chem 1990; 265:16863-6.
-
(1990)
J Biol Chem
, vol.265
, pp. 16863-16866
-
-
Liang, Y.1
Najafi, H.2
Matschinsky, F.M.3
-
33
-
-
0019641449
-
Regulation of glucose metabolism in pancreatic islets
-
Trus MD, Zawalich WS, Burch PT, Berner DK, Weill VA, Matschinsky FM. Regulation of glucose metabolism in pancreatic islets. Diabetes 1981; 30:911-22.
-
(1981)
Diabetes
, vol.30
, pp. 911-922
-
-
Trus, M.D.1
Zawalich, W.S.2
Burch, P.T.3
Berner, D.K.4
Weill, V.A.5
Matschinsky, F.M.6
-
35
-
-
0942298243
-
Prolactin, progesterone and dexamethasone coordinately and adversely regulate glucokinase and cAMP/PDE cascades in MIN6-β-cells
-
Shao J, Qiao L, Friedman JE. Prolactin, progesterone and dexamethasone coordinately and adversely regulate glucokinase and cAMP/PDE cascades in MIN6-β-cells. Am J Physiol Endocr Metab 2004; 286:304-10.
-
(2004)
Am J Physiol Endocr Metab
, vol.286
, pp. 304-310
-
-
Shao, J.1
Qiao, L.2
Friedman, J.E.3
-
36
-
-
4143051266
-
Expression and functional activity of PPARγ in pancreatic β-cells
-
Welter HJ, McBain SC, Tadayyon M, Scarpello JHB, Smith SA, Morgan NG. Expression and functional activity of PPARγ in pancreatic β-cells. British J of Pharmacol 2004; 142:1162-70.
-
(2004)
British J of Pharmacol
, vol.142
, pp. 1162-1170
-
-
Welter, H.J.1
McBain, S.C.2
Tadayyon, M.3
Scarpello, J.H.B.4
Smith, S.A.5
Morgan, N.G.6
-
37
-
-
0035078830
-
Uncoupling protein 2: A possible link between fatty acid excess and impaired glucose-induced insulin secretion
-
Lameloise N, Muzzin P, Prentki M, Assimacopoulos-Jeannet F. Uncoupling protein 2: A possible link between fatty acid excess and impaired glucose-induced insulin secretion. Diabetes 2001; 50:803-9.
-
(2001)
Diabetes
, vol.50
, pp. 803-809
-
-
Lameloise, N.1
Muzzin, P.2
Prentki, M.3
Assimacopoulos-Jeannet, F.4
|