5,7,3'-trihydroxy-3,4'-dimethoxyflavone inhibits the tubulin polymerization and activates the sphingomyelin pathway

Molecular Carcinogenesis

Volumn 50, Issue 2, 2011, Pages 113-122

  Torres, Fernando ^a,b   Quintana, José ^a,b   Estévez, Francisco ^a,b  

^a UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^b Madrid Spain   (Spain)

Author keywords

Apoptosis; Cdk1; Cell cycle arrest; Cyclins; Flavonoids; P21Cip1

Indexed keywords

3',5,7 TRIHYDROXY 3,4',6 DIMETHOXYFLAVONE; CYCLIN B1; CYCLIN DEPENDENT KINASE INHIBITOR 1; DESIPRAMINE; FLAVONOID; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CELL CYCLE ARREST; CELL CYCLE M PHASE; CELL DEATH; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKEMIA CELL; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CDC2 PROTEIN KINASE; CDC25 PHOSPHATASES; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CYCLIN B1; DESIPRAMINE; FEMALE; FLAVONES; HL-60 CELLS; HUMANS; LEUKEMIA; MICE; MICE, NUDE; PHOSPHORYLATION; POLYMERIZATION; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELINS; TUBULIN; TUBULIN MODULATORS; U937 CELLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS MUSCULUS;

EID: 78651422713     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20693     Document Type: Article

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