메뉴 건너뛰기




Volumn 4, Issue , 2005, Pages

p21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and oncophenotype reversion in Rhabdomyosarcoma cells

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYCLIN DEPENDENT KINASE INHIBITOR 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOD PROTEIN; MYOGENIN; SMALL INTERFERING RNA; TISSUE PLASMINOGEN ACTIVATOR; TRANSCRIPTION FACTOR; 1,3 BUTADIENE DERIVATIVE; BIOLOGICAL MARKER; CYCLIN DEPENDENT KINASE INHIBITOR 1A; MITOGEN ACTIVATED PROTEIN KINASE; NITRILE; PHORBOL 13 ACETATE 12 MYRISTATE;

EID: 29244459745     PISSN: 14764598     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-4-41     Document Type: Article
Times cited : (71)

References (51)
  • 1
    • 18344372831 scopus 로고    scopus 로고
    • Cyclins and cdks in development and cancer: A perspective
    • Deshpande A, Sicinski P, Hinds PW: Cyclins and cdks in development and cancer: a perspective. Oncogene 2005, 24:2909-2915.
    • (2005) Oncogene , vol.24 , pp. 2909-2915
    • Deshpande, A.1    Sicinski, P.2    Hinds, P.W.3
  • 2
    • 4344716728 scopus 로고    scopus 로고
    • Cell cycle checkpoint control mechanisms that can be disrupted in cancer
    • Dash BC and El Deiry WS: Cell cycle checkpoint control mechanisms that can be disrupted in cancer. Methods Mol.Biol. 2004, 280:99-161.
    • (2004) Methods Mol. Biol. , vol.280 , pp. 99-161
    • Dash, B.C.1    El Deiry, W.S.2
  • 3
    • 0030612164 scopus 로고    scopus 로고
    • Control of the G1/S transition
    • Reed SI: Control of the G1/S transition. Cancer Surv. 1997, 29:7-23.
    • (1997) Cancer Surv. , vol.29 , pp. 7-23
    • Reed, S.I.1
  • 4
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ and Roberts JM: CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999, 13:1501-1512.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 5
    • 0033080402 scopus 로고    scopus 로고
    • Transcriptional regulation of the p21((WAF1/CIP1)) gene
    • Gartel AL and Tyner AL: Transcriptional regulation of the p21((WAF1/CIP1)) gene. Exp. Cell Res. 1999, 246:280-289.
    • (1999) Exp. Cell Res. , vol.246 , pp. 280-289
    • Gartel, A.L.1    Tyner, A.L.2
  • 6
    • 0034815687 scopus 로고    scopus 로고
    • P53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization
    • Park JW, Jang MA, Lee YH, Passaniti A, Kwon TK: p53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization. Biochem.Biophys.Res.Commun. 2001, 280:244-248.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 244-248
    • Park, J.W.1    Jang, M.A.2    Lee, Y.H.3    Passaniti, A.4    Kwon, T.K.5
  • 7
    • 0033082834 scopus 로고    scopus 로고
    • p21WAF1 expression by an activator of protein kinase C is regulated mainly at the post-transcriptional level in cells lacking p53: Important role of RNA stabilization
    • Akashi M, Osawa Y, Koeffler HP, Hachiya M: p21WAF1 expression by an activator of protein kinase C is regulated mainly at the post-transcriptional level in cells lacking p53: important role of RNA stabilization. Biochem.J. 1999, 337 (Pt 3):607-616.
    • (1999) Biochem. J. , vol.337 , Issue.PART 3 , pp. 607-616
    • Akashi, M.1    Osawa, Y.2    Koeffler, H.P.3    Hachiya, M.4
  • 8
    • 0038219632 scopus 로고    scopus 로고
    • Ras promotes p21(Waf1/Cip1) protein stability via a cyclin D1-imposed block in proteasome-mediated degradation
    • Coleman ML, Marshall CJ, Olson MF: Ras promotes p21(Waf1/Cip1) protein stability via a cyclin D1-imposed block in proteasome-mediated degradation. EMBO J. 2003, 22:2036-2046.
    • (2003) EMBO J. , vol.22 , pp. 2036-2046
    • Coleman, M.L.1    Marshall, C.J.2    Olson, M.F.3
  • 9
    • 0037742311 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase cascade promotes myoblast cell survival by stabilizing the cyclin-dependent kinase inhibitor, p21WAF1 protein
    • Ostrovsky O and Bengal E: The mitogen-activated protein kinase cascade promotes myoblast cell survival by stabilizing the cyclin-dependent kinase inhibitor, p21WAF1 protein. J.Biol.Chem. 2003, 278:21221-21231.
    • (2003) J. Biol. Chem. , vol.278 , pp. 21221-21231
    • Ostrovsky, O.1    Bengal, E.2
  • 10
    • 0029034451 scopus 로고
    • MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation
    • Guo K, Wand J, Andres V, Smith RC, Walsh K: MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol.Cell Biol. 1995, 15:3823-3829.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3823-3829
    • Guo, K.1    Wand, J.2    Andres, V.3    Smith, R.C.4    Walsh, K.5
  • 14
    • 0030722189 scopus 로고    scopus 로고
    • Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases
    • Bennett AM and Tonks NK: Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases. Science 1997, 278:1288-1291.
    • (1997) Science , vol.278 , pp. 1288-1291
    • Bennett, A.M.1    Tonks, N.K.2
  • 15
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley S, Paterson H, Kemp P, Marshall CJ: Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 1994, 77:841-852.
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 16
    • 0032562574 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells
    • Gredinger E, Gerber AN, Tamir Y, Tapscott SJ, Bengal E: Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells. J.Biol.Chem. 1998, 273:10436-10444.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10436-10444
    • Gredinger, E.1    Gerber, A.N.2    Tamir, Y.3    Tapscott, S.J.4    Bengal, E.5
  • 17
    • 0032521642 scopus 로고    scopus 로고
    • The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic
    • Tombes RM, Auer KL, Mikkelsen R, Valerie K, Wymann MP, Marshall CJ, McMahon M, Dent P: The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic. Biochem.J. 1998, 330 (Pt 3):1451-1460.
    • (1998) Biochem. J. , vol.330 , Issue.PART 3 , pp. 1451-1460
    • Tombes, R.M.1    Auer, K.L.2    Mikkelsen, R.3    Valerie, K.4    Wymann, M.P.5    Marshall, C.J.6    McMahon, M.7    Dent, P.8
  • 18
    • 0037379794 scopus 로고    scopus 로고
    • ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK)
    • Aguirre-Ghiso JA, Estrada Y, Liu D, Ossowski L: ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK). Cancer Res. 2003, 63:1684-1695.
    • (2003) Cancer Res. , vol.63 , pp. 1684-1695
    • Aguirre-Ghiso, J.A.1    Estrada, Y.2    Liu, D.3    Ossowski, L.4
  • 19
    • 0034671847 scopus 로고    scopus 로고
    • The p38 pathway provides negative feedback for Ras proliferative signaling
    • Chen G, Hitomi M, Han J, Stacey DW: The p38 pathway provides negative feedback for Ras proliferative signaling. J.Biol.Chem. 2000, 275:38973-38980.
    • (2000) J. Biol. Chem. , vol.275 , pp. 38973-38980
    • Chen, G.1    Hitomi, M.2    Han, J.3    Stacey, D.W.4
  • 21
    • 0033062014 scopus 로고    scopus 로고
    • Rhabdomyosarcoma: An overview
    • Dagher R and Helman L: Rhabdomyosarcoma: an overview. Oncologist. 1999, 4:34-44.
    • (1999) Oncologist , vol.4 , pp. 34-44
    • Dagher, R.1    Helman, L.2
  • 22
    • 0033205985 scopus 로고    scopus 로고
    • Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma
    • Anderson J, Gordon A, McManus A, Shipley J, Pritchard-Jones K: Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma. Neoplasia. 1999, 1:340-348.
    • (1999) Neoplasia , vol.1 , pp. 340-348
    • Anderson, J.1    Gordon, A.2    McManus, A.3    Shipley, J.4    Pritchard-Jones, K.5
  • 23
    • 0027414452 scopus 로고
    • Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis
    • Tapscott SJ, Thayer MJ, Weintraub H: Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis. Science 1993, 259:1450-1453.
    • (1993) Science , vol.259 , pp. 1450-1453
    • Tapscott, S.J.1    Thayer, M.J.2    Weintraub, H.3
  • 24
    • 0035839886 scopus 로고    scopus 로고
    • Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma
    • Barr FG: Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma. Oncogene 2001, 20:5736-5746.
    • (2001) Oncogene , vol.20 , pp. 5736-5746
    • Barr, F.G.1
  • 25
    • 0029901963 scopus 로고    scopus 로고
    • The MDM2 oncoprotein is overexpressed in rhabdomyosarcoma cell lines and stabilizes wild-type p53 protein
    • Keleti J, Quezado MM, Abaza MM, Raffeld M, Tsokos M: The MDM2 oncoprotein is overexpressed in rhabdomyosarcoma cell lines and stabilizes wild-type p53 protein. Am.J.Pathol. 1996, 149:143-151.
    • (1996) Am. J. Pathol. , vol.149 , pp. 143-151
    • Keleti, J.1    Quezado, M.M.2    Abaza, M.M.3    Raffeld, M.4    Tsokos, M.5
  • 29
    • 0042838283 scopus 로고    scopus 로고
    • Muscle regulatory factor MRF4 activates differentiation in rhabdomyosarcoma RD cells through a positive-acting C-terminal protein domain
    • Sirri V, Leibovitch MP, Leibovitch SA: Muscle regulatory factor MRF4 activates differentiation in rhabdomyosarcoma RD cells through a positive-acting C-terminal protein domain. Oncogene 2003, 22:5658-5666.
    • (2003) Oncogene , vol.22 , pp. 5658-5666
    • Sirri, V.1    Leibovitch, M.P.2    Leibovitch, S.A.3
  • 31
    • 0024429019 scopus 로고
    • Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
    • Chen PL, Scully P, Shew JY, Wang JY, Lee WH: Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell 1989, 58:1193-1198.
    • (1989) Cell , vol.58 , pp. 1193-1198
    • Chen, P.L.1    Scully, P.2    Shew, J.Y.3    Wang, J.Y.4    Lee, W.H.5
  • 32
    • 0037119470 scopus 로고    scopus 로고
    • The stress-activated protein kinases p38 alpha and JNK1 stabilize p21 (Cip1) by phosphorylation
    • Kim GY, Mercer SE, Ewton DZ, Yan Z, Jin K, Friedman E: The stress-activated protein kinases p38 alpha and JNK1 stabilize p21 (Cip1) by phosphorylation. J.Biol.Chem. 2002, 277:29792-29802.
    • (2002) J. Biol. Chem. , vol.277 , pp. 29792-29802
    • Kim, G.Y.1    Mercer, S.E.2    Ewton, D.Z.3    Yan, Z.4    Jin, K.5    Friedman, E.6
  • 34
    • 0034723357 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase negatively regulates the induction of phase II drugmetabolizing enzymes that detoxify carcinogens
    • Yu R, Mandlekar S, Lei W, Fahl WE, Tan TH, Kong AT: p38 mitogen-activated protein kinase negatively regulates the induction of phase II drugmetabolizing enzymes that detoxify carcinogens. J.Biol.Chem. 2000, 275:2322-2327.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2322-2327
    • Yu, R.1    Mandlekar, S.2    Lei, W.3    Fahl, W.E.4    Tan, T.H.5    Kong, A.T.6
  • 36
    • 0033104495 scopus 로고    scopus 로고
    • Apoptosis inhibitory activity of cytoplasmic p21 (Cip1/WAF1) in monocytic differentiation
    • Asada M, Yamada T, Ichijo H, Delia D, Miyazono K, Fukumuro K, Mizutani S: Apoptosis inhibitory activity of cytoplasmic p21 (Cip1/WAF1) in monocytic differentiation. EMBO J. 1999, 18:1223-1234.
    • (1999) EMBO J. , vol.18 , pp. 1223-1234
    • Asada, M.1    Yamada, T.2    Ichijo, H.3    Delia, D.4    Miyazono, K.5    Fukumuro, K.6    Mizutani, S.7
  • 37
    • 0029808931 scopus 로고    scopus 로고
    • Effects of ectopic overexpression of p21(WAF1/CIP1) on aneuploidy and the malignant phenotype of human brain tumor cells
    • Chen J, Willingham T, Shuford M, Bruce D, Rushing E, Smith Y, Nisen PD: Effects of ectopic overexpression of p21(WAF1/CIP1) on aneuploidy and the malignant phenotype of human brain tumor cells. Oncogene 1996, 13:1395-1403.
    • (1996) Oncogene , vol.13 , pp. 1395-1403
    • Chen, J.1    Willingham, T.2    Shuford, M.3    Bruce, D.4    Rushing, E.5    Smith, Y.6    Nisen, P.D.7
  • 38
    • 0033176887 scopus 로고    scopus 로고
    • SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
    • Carrano AC, Eytan E, Hershko A, Pagano M: SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat.Cell Biol. 1999, 1:193-199.
    • (1999) Nat. Cell Biol. , vol.1 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3    Pagano, M.4
  • 39
    • 0034947868 scopus 로고    scopus 로고
    • Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation
    • Miskimins WK, Wang G, Hawkinson M, Miskimins R: Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation. Mol.Cell Biol. 2001, 21:4960-4967.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 4960-4967
    • Miskimins, W.K.1    Wang, G.2    Hawkinson, M.3    Miskimins, R.4
  • 40
    • 19644388719 scopus 로고    scopus 로고
    • Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1
    • Gysin S, Lee SH, Dean NM, McMahon M: Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1. Cancer Res. 2005, 65:4870-4880.
    • (2005) Cancer Res. , vol.65 , pp. 4870-4880
    • Gysin, S.1    Lee, S.H.2    Dean, N.M.3    McMahon, M.4
  • 41
    • 26444454582 scopus 로고    scopus 로고
    • Inhibition of extracellular signal regulated kinase (ERK) leads to apoptosis inducing factor (AIF) mediated apoptosis in epithelial breast cancer cells: The lack of effect of ERK in p53 mediated copper induced apoptosis
    • Ostrakhovitch EA and Cherian MG: Inhibition of extracellular signal regulated kinase (ERK) leads to apoptosis inducing factor (AIF) mediated apoptosis in epithelial breast cancer cells: The lack of effect of ERK in p53 mediated copper induced apoptosis. J.Cell Biochem. 2005, 95:1120-1134.
    • (2005) J. Cell Biochem. , vol.95 , pp. 1120-1134
    • Ostrakhovitch, E.A.1    Cherian, M.G.2
  • 43
    • 0034162714 scopus 로고    scopus 로고
    • Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells
    • Puri PL, Wu Z, Zhang P, Wood LD, Bhakta KS, Han J, Feramisco JR, Karin M, Wang JY: Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes Dev. 2000, 14:574-584.
    • (2000) Genes Dev. , vol.14 , pp. 574-584
    • Puri, P.L.1    Wu, Z.2    Zhang, P.3    Wood, L.D.4    Bhakta, K.S.5    Han, J.6    Feramisco, J.R.7    Karin, M.8    Wang, J.Y.9
  • 45
    • 0035895630 scopus 로고    scopus 로고
    • Regulation of MyoD function in the dividing myoblast
    • Wei Q and Paterson BM: Regulation of MyoD function in the dividing myoblast. FEBS Lett. 2001, 490:171-178.
    • (2001) FEBS Lett. , vol.490 , pp. 171-178
    • Wei, Q.1    Paterson, B.M.2
  • 47
    • 0026802989 scopus 로고
    • Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
    • Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA: Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 1992, 70:993-1006.
    • (1992) Cell , vol.70 , pp. 993-1006
    • Hinds, P.W.1    Mittnacht, S.2    Dulic, V.3    Arnold, A.4    Reed, S.I.5    Weinberg, R.A.6
  • 49
    • 0023663888 scopus 로고
    • Expression of a single transfected cDNA converts fibroblasts to myoblasts
    • Davis RL, Weintraub H, Lassar AB: Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 1987, 51:987-1000.
    • (1987) Cell , vol.51 , pp. 987-1000
    • Davis, R.L.1    Weintraub, H.2    Lassar, A.B.3
  • 50
    • 0024576880 scopus 로고
    • Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD
    • Wright WE, Sassoon DA, Lin VK: Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD. Cell 1989, 56:607-617.
    • (1989) Cell , vol.56 , pp. 607-617
    • Wright, W.E.1    Sassoon, D.A.2    Lin, V.K.3
  • 51
    • 0030033473 scopus 로고    scopus 로고
    • Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses
    • Mansour SJ, Candia JM, Gloor KK, Ahn NG: Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses. Cell Growth Differ. 1996, 7:243-250.
    • (1996) Cell Growth Differ. , vol.7 , pp. 243-250
    • Mansour, S.J.1    Candia, J.M.2    Gloor, K.K.3    Ahn, N.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.