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Volumn 24, Issue 1, 2011, Pages 35-50

Artificial skin in perspective: Concepts and applications

Author keywords

3D models; Artificial skin; Organotypical cultures; Rafts; Skin equivalents; Skin reconstructs

Indexed keywords

ARTIFICIAL SKIN; BASEMENT MEMBRANE; CELL INTERACTION; CELL LINE; DERMIS; EPIDERMIS; EXTRACELLULAR MATRIX; HUMAN; IMMUNE SYSTEM; IN VITRO STUDY; NONHUMAN; PHOTOAGING; REVIEW; SKIN CANCER; SKIN CELL; SKIN DISEASE; SKIN FIBROBLAST; SKIN FUNCTION; SKIN PIGMENTATION; ULTRAVIOLET RADIATION; WOUND HEALING;

EID: 78651414332     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00786.x     Document Type: Review
Times cited : (195)

References (112)
  • 1
    • 34547206811 scopus 로고    scopus 로고
    • Cellular responses to disruption of the permeability barrier in a three-dimensional organotypic epidermal model
    • Ajani, G., Sato, N., Mack, J.A., and Maytin, E.V. (2007). Cellular responses to disruption of the permeability barrier in a three-dimensional organotypic epidermal model. Exp. Cell Res. 313, 3005-3015.
    • (2007) Exp. Cell Res. , vol.313 , pp. 3005-3015
    • Ajani, G.1    Sato, N.2    Mack, J.A.3    Maytin, E.V.4
  • 2
    • 51749119454 scopus 로고    scopus 로고
    • E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents
    • Alt-Holland, A., Shamis, Y., Riley, K.N., DesRochers, T.M., Fusenig, N.E., Herman, I.M., and Garlick, J.A. (2008). E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents. J. Invest. Dermatol. 128, 2498-2507.
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 2498-2507
    • Alt-Holland, A.1    Shamis, Y.2    Riley, K.N.3    DesRochers, T.M.4    Fusenig, N.E.5    Herman, I.M.6    Garlick, J.A.7
  • 3
    • 0021926418 scopus 로고
    • Epidermal morphogenesis and induction of 67kD keratin polypeptide by culture at the liquid-air interface
    • Asselineau, D., Bernard, B.A., Bailly, C., and Darmon, M. (1985). Epidermal morphogenesis and induction of 67kD keratin polypeptide by culture at the liquid-air interface. Exp. Cell Res. 159, 536-539.
    • (1985) Exp. Cell Res , vol.159 , pp. 536-539
    • Asselineau, D.1    Bernard, B.A.2    Bailly, C.3    Darmon, M.4
  • 5
    • 0034953444 scopus 로고    scopus 로고
    • Skin substitutes: a review
    • Balasubramani, M., Kumar, T.R., and Babu, M. (2001). Skin substitutes: a review. Burns 27, 534-544.
    • (2001) Burns , vol.27 , pp. 534-544
    • Balasubramani, M.1    Kumar, T.R.2    Babu, M.3
  • 7
    • 0001297636 scopus 로고
    • Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro
    • Bell, E., Ivarsson, B., and Merrill, C. (1979). Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc. Natl Acad. Sci. U S A 76, 1274-1278.
    • (1979) Proc. Natl Acad. Sci. U S A , vol.76 , pp. 1274-1278
    • Bell, E.1    Ivarsson, B.2    Merrill, C.3
  • 9
    • 0035071889 scopus 로고    scopus 로고
    • Human skin reconstruct models: a new application for studies of melanocyte and melanoma biology
    • Berking, C., and Herlyn, M. (2001). Human skin reconstruct models: a new application for studies of melanocyte and melanoma biology. Histol. Histopathol. 16, 669-674.
    • (2001) Histol. Histopathol. , vol.16 , pp. 669-674
    • Berking, C.1    Herlyn, M.2
  • 10
    • 0031569350 scopus 로고    scopus 로고
    • Successive alteration and recovery of epidermal differentiation and morphogenesis after specific UVB-damages in skin reconstructed in vitro
    • Bernerd, F., and Asselineau, D. (1997). Successive alteration and recovery of epidermal differentiation and morphogenesis after specific UVB-damages in skin reconstructed in vitro. Dev. Biol. 183, 123-138.
    • (1997) Dev. Biol. , vol.183 , pp. 123-138
    • Bernerd, F.1    Asselineau, D.2
  • 11
    • 0031787362 scopus 로고    scopus 로고
    • UVA exposure of human skin reconstructed in vitro induces apoptosis of dermal fibroblasts: subsequent connective tissue repair and implications in photoaging
    • Bernerd, F., and Asselineau, D. (1998). UVA exposure of human skin reconstructed in vitro induces apoptosis of dermal fibroblasts: subsequent connective tissue repair and implications in photoaging. Cell Death Differ. 5, 792-802.
    • (1998) Cell Death Differ. , vol.5 , pp. 792-802
    • Bernerd, F.1    Asselineau, D.2
  • 12
    • 41849132082 scopus 로고    scopus 로고
    • An organotypic model of skin to study photodamage and photoprotection in vitro
    • Bernerd, F., and Asselineau, D. (2008). An organotypic model of skin to study photodamage and photoprotection in vitro. J. Am. Acad. Dermatol. 58, S155-S159.
    • (2008) J. Am. Acad. Dermatol. , vol.58
    • Bernerd, F.1    Asselineau, D.2
  • 13
    • 0034161249 scopus 로고    scopus 로고
    • Evaluation of the protective effect of sunscreens on in vitro reconstructed human skin exposed to UVB or UVA irradiation
    • Bernerd, F., Vioux, C., and Asselineau, D. (2000). Evaluation of the protective effect of sunscreens on in vitro reconstructed human skin exposed to UVB or UVA irradiation. Photochem. Photobiol. 71, 314-320.
    • (2000) Photochem. Photobiol. , vol.71 , pp. 314-320
    • Bernerd, F.1    Vioux, C.2    Asselineau, D.3
  • 15
    • 0031449728 scopus 로고    scopus 로고
    • Epidermal reconstructs in vitiligo: an extrinsic factor is needed to trigger the disease
    • Bessou, S., Gauthier, Y., Surlève-Bazeille, J.E., Pain, C., and Taïeb, A. (1997). Epidermal reconstructs in vitiligo: an extrinsic factor is needed to trigger the disease. Br. J. Dermatol. 137, 890-897.
    • (1997) Br. J. Dermatol. , vol.137 , pp. 890-897
    • Bessou, S.1    Gauthier, Y.2    Surlève-Bazeille, J.E.3    Pain, C.4    Taïeb, A.5
  • 16
    • 0020456385 scopus 로고
    • How does the extracellular matrix direct gene expression?
    • Bissell, M.J., Hall, H.G., and Parry, G. (1982). How does the extracellular matrix direct gene expression? J. Theor. Biol. 99, 31-68.
    • (1982) J. Theor. Biol. , vol.99 , pp. 31-68
    • Bissell, M.J.1    Hall, H.G.2    Parry, G.3
  • 17
    • 5344266707 scopus 로고    scopus 로고
    • HPV-18 confers resistance to TNF-alpha in organotypic cultures of human keratinocytes
    • Boccardo, E., Noya, F., Broker, T.R., Chow, L.T., and Villa, L.L. (2004). HPV-18 confers resistance to TNF-alpha in organotypic cultures of human keratinocytes. Virology 328, 233-243.
    • (2004) Virology , vol.328 , pp. 233-243
    • Boccardo, E.1    Noya, F.2    Broker, T.R.3    Chow, L.T.4    Villa, L.L.5
  • 18
    • 36048991203 scopus 로고    scopus 로고
    • Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents
    • Boehnke, K., Mirancea, N., Pavesio, A., Fusenig, N.E., Boukamp, P., and Stark, H.J. (2007). Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents. Eur. J. Cell Biol. 86, 731-746.
    • (2007) Eur. J. Cell Biol. , vol.86 , pp. 731-746
    • Boehnke, K.1    Mirancea, N.2    Pavesio, A.3    Fusenig, N.E.4    Boukamp, P.5    Stark, H.J.6
  • 19
    • 0032959859 scopus 로고    scopus 로고
    • Reconstruction of a human skin equivalent using a spontaneously transformed keratinocyte cell line (HaCaT)
    • Boelsma, E., Verhoeven, M.C., and Ponec, M. (1999). Reconstruction of a human skin equivalent using a spontaneously transformed keratinocyte cell line (HaCaT). J. Invest. Dermatol. 112, 489-498.
    • (1999) J. Invest. Dermatol. , vol.112 , pp. 489-498
    • Boelsma, E.1    Verhoeven, M.C.2    Ponec, M.3
  • 20
    • 0033823347 scopus 로고    scopus 로고
    • Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation
    • Boelsma, E., Gibbs, S., Faller, C., and Ponec, M. (2000). Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation. Acta Derm. Venereol. 80, 82-88.
    • (2000) Acta Derm. Venereol. , vol.80 , pp. 82-88
    • Boelsma, E.1    Gibbs, S.2    Faller, C.3    Ponec, M.4
  • 21
    • 1842665844 scopus 로고    scopus 로고
    • The validation of in vitro methods for skin irritation
    • Botham, P.A. (2004). The validation of in vitro methods for skin irritation. Toxicol. Lett. 149, 387-390.
    • (2004) Toxicol. Lett. , vol.149 , pp. 387-390
    • Botham, P.A.1
  • 22
    • 0036227481 scopus 로고    scopus 로고
    • Principles and practices for treatment of cutaneous wounds with cultured skin substitutes
    • Boyce, S.T., and Warden, G.D. (2002). Principles and practices for treatment of cutaneous wounds with cultured skin substitutes. Am. J. Surg. 183, 445-456.
    • (2002) Am. J. Surg. , vol.183 , pp. 445-456
    • Boyce, S.T.1    Warden, G.D.2
  • 23
    • 38049092798 scopus 로고    scopus 로고
    • Use of organotypic coculture to study keloid biology
    • Butler, P.D., Ly, D.P., Longaker, M.T., and Yang, G.P. (2008). Use of organotypic coculture to study keloid biology. Am. J. Surg. 195, 144-148.
    • (2008) Am. J. Surg. , vol.195 , pp. 144-148
    • Butler, P.D.1    Ly, D.P.2    Longaker, M.T.3    Yang, G.P.4
  • 24
    • 33748319360 scopus 로고    scopus 로고
    • In vivo and in vitro evidence of dermal fibroblasts influence on human epidermal pigmentation
    • Cario-André, M., Pain, C., Gauthier, Y. et al. (2006). In vivo and in vitro evidence of dermal fibroblasts influence on human epidermal pigmentation. Pigment Cell Res. 19, 434-442.
    • (2006) Pigment Cell Res. , vol.19 , pp. 434-442
    • Cario-André, M.1    Pain, C.2    Gauthier, Y.3
  • 25
    • 34548580278 scopus 로고    scopus 로고
    • The melanocytorrhagic hypothesis of vitiligo tested on pigmented, stressed, reconstructed epidermis
    • Cario-André, M., Pain, C., Gauthier, Y., and Taïeb, A. (2007). The melanocytorrhagic hypothesis of vitiligo tested on pigmented, stressed, reconstructed epidermis. Pigment Cell Res. 20, 385-393.
    • (2007) Pigment Cell Res. , vol.20 , pp. 385-393
    • Cario-André, M.1    Pain, C.2    Gauthier, Y.3    Taïeb, A.4
  • 26
    • 77956616000 scopus 로고    scopus 로고
    • Organotypic modelling as a means of investigating epithelial-stromal interactions during tumourigenesis
    • Chioni, A.M., and Grose, R. (2008). Organotypic modelling as a means of investigating epithelial-stromal interactions during tumourigenesis. Fibrogenesis Tissue Repair. 1, 8.
    • (2008) Fibrogenesis Tissue Repair. , vol.1 , pp. 8
    • Chioni, A.M.1    Grose, R.2
  • 27
    • 26844445631 scopus 로고    scopus 로고
    • Photodynamic therapy on keloid fibroblasts in tissue-engineered keratinocyte-fibroblast co-culture
    • Chiu, L.L., Sun, C.H., Yeh, A.T., Torkian, B., Karamzadeh, A., Tromberg, B., and Wong, B.J. (2005). Photodynamic therapy on keloid fibroblasts in tissue-engineered keratinocyte-fibroblast co-culture. Lasers Surg. Med. 37, 231-244.
    • (2005) Lasers Surg. Med. , vol.37 , pp. 231-244
    • Chiu, L.L.1    Sun, C.H.2    Yeh, A.T.3    Torkian, B.4    Karamzadeh, A.5    Tromberg, B.6    Wong, B.J.7
  • 28
    • 0026092350 scopus 로고
    • In vivo optimization of a living dermal substitute employing cultured human fibroblasts on a biodegradable polyglycolic acid or polyglactin mesh
    • Cooper, M.L., Hansbrough, J.F., Spielvogel, R.L., Cohen, R., Bartel, R.L., and Naughton, G. (1991). In vivo optimization of a living dermal substitute employing cultured human fibroblasts on a biodegradable polyglycolic acid or polyglactin mesh. Biomaterials 12, 243-248.
    • (1991) Biomaterials , vol.12 , pp. 243-248
    • Cooper, M.L.1    Hansbrough, J.F.2    Spielvogel, R.L.3    Cohen, R.4    Bartel, R.L.5    Naughton, G.6
  • 29
    • 33947616725 scopus 로고    scopus 로고
    • Human skin pigmentation: melanocytes modulate skin color in response to stress
    • Costin, G.E., and Hearing, V.J. (2007). Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J. 21, 976-994.
    • (2007) FASEB J. , vol.21 , pp. 976-994
    • Costin, G.E.1    Hearing, V.J.2
  • 30
    • 33746279142 scopus 로고    scopus 로고
    • Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm)
    • Curren, R.D., Mun, G.C., Gibson, D.P., and Aardema, M.J. (2006). Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm). Mutat. Res. 607, 192-204.
    • (2006) Mutat. Res. , vol.607 , pp. 192-204
    • Curren, R.D.1    Mun, G.C.2    Gibson, D.P.3    Aardema, M.J.4
  • 31
    • 67649948869 scopus 로고    scopus 로고
    • Gene therapy of inherited skin adhesion disorders: a critical overview
    • De Luca, M., Pellegrini, G., and Mavilio, F. (2009). Gene therapy of inherited skin adhesion disorders: a critical overview. Br. J. Dermatol. 161, 19-24.
    • (2009) Br. J. Dermatol. , vol.161 , pp. 19-24
    • De Luca, M.1    Pellegrini, G.2    Mavilio, F.3
  • 32
    • 0032599998 scopus 로고    scopus 로고
    • Selective uptake and sustained expression of AAV vectors following subcutaneous delivery
    • Donahue, B.A., McArthur, J.G., Spratt, S.K. et al. (1999). Selective uptake and sustained expression of AAV vectors following subcutaneous delivery. J Gene Med. 1, 31-42.
    • (1999) J Gene Med. , vol.1 , pp. 31-42
    • Donahue, B.A.1    McArthur, J.G.2    Spratt, S.K.3
  • 33
    • 78651425695 scopus 로고    scopus 로고
    • Restoration of the transepithelial potential within tissue-engineered human skin in vitro and during the wound healing process in vivo
    • Dubé, J., Rochette-Drouin, O., Lévesque, P. et al. (2010). Restoration of the transepithelial potential within tissue-engineered human skin in vitro and during the wound healing process in vivo. Tissue Eng Part A 32, 238-243.
    • (2010) Tissue Eng Part A , vol.32 , pp. 238-243
    • Dubé, J.1    Rochette-Drouin, O.2    Lévesque, P.3
  • 35
    • 12244301580 scopus 로고    scopus 로고
    • Crucial role of fibroblasts in regulating epidermal morphogenesis
    • El Ghalbzouri, A., Lamme, E., and Ponec, M. (2002b). Crucial role of fibroblasts in regulating epidermal morphogenesis. Cell Tissue Res. 310, 189-199.
    • (2002) Cell Tissue Res. , vol.310 , pp. 189-199
    • El Ghalbzouri, A.1    Lamme, E.2    Ponec, M.3
  • 36
    • 11944260893 scopus 로고    scopus 로고
    • Basement membrane reconstruction in human skin equivalents is regulated by fibroblasts and/or exogenously activated keratinocytes
    • El Ghalbzouri, A., Jonkman, M.F., Dijkman, R., and Ponec, M. (2005). Basement membrane reconstruction in human skin equivalents is regulated by fibroblasts and/or exogenously activated keratinocytes. J. Invest. Dermatol. 124, 79-86.
    • (2005) J. Invest. Dermatol. , vol.124 , pp. 79-86
    • El Ghalbzouri, A.1    Jonkman, M.F.2    Dijkman, R.3    Ponec, M.4
  • 37
    • 44749093939 scopus 로고    scopus 로고
    • Leiden reconstructed human epidermal model as a tool for the evaluation of the skin corrosion and irritation potential according to the ECVAM guidelines
    • El Ghalbzouri, A., Siamari, R., Willemze, R., and Ponec, M. (2008). Leiden reconstructed human epidermal model as a tool for the evaluation of the skin corrosion and irritation potential according to the ECVAM guidelines. Toxicol In Vitro. 22, 1311-1320.
    • (2008) Toxicol In Vitro. , vol.22 , pp. 1311-1320
    • El Ghalbzouri, A.1    Siamari, R.2    Willemze, R.3    Ponec, M.4
  • 38
    • 0036786391 scopus 로고    scopus 로고
    • Is facial resurfacing with monobloc full-thickness skin graft a remedy in xeroderma pigmentosum?
    • Ergün, S.S., Cek, D.I., and Demirkesen, C. (2002). Is facial resurfacing with monobloc full-thickness skin graft a remedy in xeroderma pigmentosum? Plast. Reconstr. Surg. 110, 1290-1293.
    • (2002) Plast. Reconstr. Surg. , vol.110 , pp. 1290-1293
    • Ergün, S.S.1    Cek, D.I.2    Demirkesen, C.3
  • 39
    • 1442299041 scopus 로고    scopus 로고
    • Langerhans cells integrated into human reconstructed epidermis respond to known sensitizers and ultraviolet exposure
    • Facy, V., Flouret, V., Régnier, M., and Schmidt, R. (2004). Langerhans cells integrated into human reconstructed epidermis respond to known sensitizers and ultraviolet exposure. J. Invest. Dermatol. 122, 552-553.
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 552-553
    • Facy, V.1    Flouret, V.2    Régnier, M.3    Schmidt, R.4
  • 41
    • 0036972762 scopus 로고    scopus 로고
    • ECVAM's activities in validating alternative tests for skin corrosion and irritation
    • Fentem, J.H., and Botham, P.A. (2002). ECVAM's activities in validating alternative tests for skin corrosion and irritation. Altern Lab Anim. 2, 61-67.
    • (2002) Altern Lab Anim. , vol.2 , pp. 61-67
    • Fentem, J.H.1    Botham, P.A.2
  • 44
    • 33645778729 scopus 로고    scopus 로고
    • Gene therapy in combination with tissue engineering to treat epidermolysis bullosa
    • Ferrari, S., Pellegrini, G., Matsui, T., Mavilio, F., and De Luca, M. (2006). Gene therapy in combination with tissue engineering to treat epidermolysis bullosa. Expert Opin. Biol. Ther. 6, 367-378.
    • (2006) Expert Opin. Biol. Ther. , vol.6 , pp. 367-378
    • Ferrari, S.1    Pellegrini, G.2    Matsui, T.3    Mavilio, F.4    De Luca, M.5
  • 46
    • 0001395573 scopus 로고
    • The melanocyte: cytology and cytochemistry
    • Fitzpatrick, T.B., and Szabo, G. (1959). The melanocyte: cytology and cytochemistry. Invest. Dermatol. 32, 197-209.
    • (1959) Invest. Dermatol. , vol.32 , pp. 197-209
    • Fitzpatrick, T.B.1    Szabo, G.2
  • 47
    • 33751075455 scopus 로고    scopus 로고
    • A characteristic subset of psoriasis-associated genes is induced by oncostatin-M in reconstituted epidermis
    • Gazel, A., Rosdy, M., Bertino, B., Tornier, C., Sahuc, F., and Blumenberg, M. (2006). A characteristic subset of psoriasis-associated genes is induced by oncostatin-M in reconstituted epidermis. J. Invest. Dermatol. 126, 2647-2657.
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 2647-2657
    • Gazel, A.1    Rosdy, M.2    Bertino, B.3    Tornier, C.4    Sahuc, F.5    Blumenberg, M.6
  • 48
    • 35349002202 scopus 로고    scopus 로고
    • Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models
    • Godin, B., and Touitou, E. (2007). Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models. Adv. Drug Deliv. Rev. 59, 1152-1161.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 1152-1161
    • Godin, B.1    Touitou, E.2
  • 51
    • 0017223151 scopus 로고
    • Biochemical analysis of cell adhesion to a substratum and its possible relevance to cell metastasis
    • Grinnell, F. (1976). Biochemical analysis of cell adhesion to a substratum and its possible relevance to cell metastasis. Prog. Clin. Biol. Res. 9, 227-236.
    • (1976) Prog. Clin. Biol. Res. , vol.9 , pp. 227-236
    • Grinnell, F.1
  • 52
    • 46749126941 scopus 로고    scopus 로고
    • Fibroblast mechanics in three-dimensional collagen matrices
    • Grinnell, F. (2008). Fibroblast mechanics in three-dimensional collagen matrices. J Bodywork Mov. Ther. 12, 191-193.
    • (2008) J Bodywork Mov. Ther. , vol.12 , pp. 191-193
    • Grinnell, F.1
  • 53
    • 19544362066 scopus 로고    scopus 로고
    • Adhesion, migration and communication in melanocytes and melanoma
    • Haass, N.K., Smalley, K.S., Li, L., and Herlyn, M. (2005). Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Res. 18, 150-159.
    • (2005) Pigment Cell Res. , vol.18 , pp. 150-159
    • Haass, N.K.1    Smalley, K.S.2    Li, L.3    Herlyn, M.4
  • 55
    • 71749109248 scopus 로고    scopus 로고
    • Xeroderma pigmentosum: radical therapeutic procedure on the face using artificial skin [in French]
    • Herlin, C., Saunière, D., and Huertas, D. (2009). Xeroderma pigmentosum: radical therapeutic procedure on the face using artificial skin [in French]. Ann. Chir. Plast. Esthet. 54, 594-599.
    • (2009) Ann. Chir. Plast. Esthet. , vol.54 , pp. 594-599
    • Herlin, C.1    Saunière, D.2    Huertas, D.3
  • 56
    • 47049123953 scopus 로고    scopus 로고
    • A feasibility study developing an integrated testing strategy assessing skin irritation potential of chemicals
    • Hoffmann, S., Saliner, A.G., Patlewicz, G., Eskes, C., Zuang, V., and Worth, A.P. (2008). A feasibility study developing an integrated testing strategy assessing skin irritation potential of chemicals. Toxicol. Lett. 180, 9-20.
    • (2008) Toxicol. Lett. , vol.180 , pp. 9-20
    • Hoffmann, S.1    Saliner, A.G.2    Patlewicz, G.3    Eskes, C.4    Zuang, V.5    Worth, A.P.6
  • 60
    • 0033838767 scopus 로고    scopus 로고
    • E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors
    • Hsu, M.Y., Meier, F.E., Nesbit, M., Hsu, J.Y., Van Belle, P., Elder, D.E., and Herlyn, M. (2000). E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am. J. Pathol. 156, 1515-1525.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1515-1525
    • Hsu, M.Y.1    Meier, F.E.2    Nesbit, M.3    Hsu, J.Y.4    Van Belle, P.5    Elder, D.E.6    Herlyn, M.7
  • 61
    • 61449159631 scopus 로고    scopus 로고
    • Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay
    • Hu, T., Kaluzhny, Y., Mun, G.C., Barnett, B., Karetsky, V., Wilt, N., Klausner, M., Curren, R.D., and Aardema, M.J. (2009). Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay. Mutat. Res. 673, 100-108.
    • (2009) Mutat. Res. , vol.673 , pp. 100-108
    • Hu, T.1    Kaluzhny, Y.2    Mun, G.C.3    Barnett, B.4    Karetsky, V.5    Wilt, N.6    Klausner, M.7    Curren, R.D.8    Aardema, M.J.9
  • 62
    • 23144436642 scopus 로고    scopus 로고
    • Basement membrane proteoglycans: from cellar to ceiling
    • Iozzo, R.V. (2005). Basement membrane proteoglycans: from cellar to ceiling. Nat. Rev. Mol. Cell Biol. 6, 646-656.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 646-656
    • Iozzo, R.V.1
  • 63
    • 22244474316 scopus 로고    scopus 로고
    • Comparative study of keloid formation in humans and laboratory animals
    • Khorshid, F.A. (2005). Comparative study of keloid formation in humans and laboratory animals. Med. Sci. Monit. 11, BR212-BR219.
    • (2005) Med. Sci. Monit. , vol.11
    • Khorshid, F.A.1
  • 64
    • 0029838729 scopus 로고    scopus 로고
    • Interleukin-8 is induced in skin equivalents and is highest in those derived from psoriatic fibroblasts
    • Konstantinova, N.V., Duong, D.M., Remenyik, E., Hazarika, P., Chuang, A., and Duvic, M. (1996). Interleukin-8 is induced in skin equivalents and is highest in those derived from psoriatic fibroblasts. J. Invest. Dermatol. 107, 615-621.
    • (1996) J. Invest. Dermatol. , vol.107 , pp. 615-621
    • Konstantinova, N.V.1    Duong, D.M.2    Remenyik, E.3    Hazarika, P.4    Chuang, A.5    Duvic, M.6
  • 65
    • 33747882661 scopus 로고    scopus 로고
    • MITF: master regulator of melanocyte development and melanoma oncogene
    • Levy, C., Khaled, M., and Fisher, D.E. (2006). MITF: master regulator of melanocyte development and melanoma oncogene. Trends Mol. Med. 12, 406-414.
    • (2006) Trends Mol. Med. , vol.12 , pp. 406-414
    • Levy, C.1    Khaled, M.2    Fisher, D.E.3
  • 66
    • 0027256508 scopus 로고
    • Multi-faceted regulation of cell differentiation by extracellular matrix
    • Lin, C.Q., and Bissell, M.J. (1993). Multi-faceted regulation of cell differentiation by extracellular matrix. FASEB J. 7, 737-743.
    • (1993) FASEB J. , vol.7 , pp. 737-743
    • Lin, C.Q.1    Bissell, M.J.2
  • 68
    • 33847256045 scopus 로고    scopus 로고
    • Progress and opportunities for tissue-engineered skin
    • MacNeil, S. (2007). Progress and opportunities for tissue-engineered skin. Nature 44, 874-880.
    • (2007) Nature , vol.44 , pp. 874-880
    • MacNeil, S.1
  • 69
    • 60149098270 scopus 로고    scopus 로고
    • Modulation of basal and squamous cell carcinoma by endogenous estrogen in mouse models of skin cancer
    • Mancuso, M., Gallo, D., Leonardi, S. et al. (2009). Modulation of basal and squamous cell carcinoma by endogenous estrogen in mouse models of skin cancer. Carcinogenesis. 30, 340-347.
    • (2009) Carcinogenesis. , vol.30 , pp. 340-347
    • Mancuso, M.1    Gallo, D.2    Leonardi, S.3
  • 70
    • 0026629850 scopus 로고
    • The dermal-epidermal junction of human skin contains a novel laminin variant
    • Marinkovich, M.P., Lunstrum, G.P., Keene, D.R., and Burgeson, R.E. (1992). The dermal-epidermal junction of human skin contains a novel laminin variant. J. Cell Biol. 119, 695-703.
    • (1992) J. Cell Biol. , vol.119 , pp. 695-703
    • Marinkovich, M.P.1    Lunstrum, G.P.2    Keene, D.R.3    Burgeson, R.E.4
  • 71
    • 33845524625 scopus 로고    scopus 로고
    • Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells
    • Mavilio, F., Pellegrini, G., Ferrari, S. et al. (2006). Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat. Med. 12, 1397-1402.
    • (2006) Nat. Med. , vol.12 , pp. 1397-1402
    • Mavilio, F.1    Pellegrini, G.2    Ferrari, S.3
  • 72
    • 77049124474 scopus 로고    scopus 로고
    • Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?
    • Mazzoleni, G., Di Lorenzo, D., and Steimberg, N. (2009). Modelling tissues in 3D: the next future of pharmaco-toxicology and food research? Genes Nutr. 4, 13-22.
    • (2009) Genes Nutr. , vol.4 , pp. 13-22
    • Mazzoleni, G.1    Di Lorenzo, D.2    Steimberg, N.3
  • 73
    • 0033883797 scopus 로고    scopus 로고
    • Human melanoma progression in skin reconstructs: biological significance of bFGF
    • Meier, F., Nesbit, M., Hsu, M.Y. et al. (2000). Human melanoma progression in skin reconstructs: biological significance of bFGF. Am. J. Pathol. 156, 193-200.
    • (2000) Am. J. Pathol. , vol.156 , pp. 193-200
    • Meier, F.1    Nesbit, M.2    Hsu, M.Y.3
  • 74
    • 0036852419 scopus 로고    scopus 로고
    • New insights into skin structure: scratching the surface
    • Menon, G.K. (2002). New insights into skin structure: scratching the surface. Adv. Drug Deliv Rev. 54(Suppl 1), S3-S17.
    • (2002) Adv. Drug Deliv Rev. , vol.54 , Issue.SUPPL 1
    • Menon, G.K.1
  • 75
    • 0031805283 scopus 로고    scopus 로고
    • Epidermal adhesion molecules and basement membrane components as target structures of autoimmunity
    • Moll, R., and Moll, I. (1998). Epidermal adhesion molecules and basement membrane components as target structures of autoimmunity. Virchows Arch. 432, 487-504.
    • (1998) Virchows Arch. , vol.432 , pp. 487-504
    • Moll, R.1    Moll, I.2
  • 76
    • 0026800892 scopus 로고
    • The cloning of a family of genes that encode the melanocortin receptors
    • Mountjoy, K.G., Robbins, L.S., Mortrud, M.T., and Cone, R.D. (1992). The cloning of a family of genes that encode the melanocortin receptors. Science 257, 1248-1251.
    • (1992) Science , vol.257 , pp. 1248-1251
    • Mountjoy, K.G.1    Robbins, L.S.2    Mortrud, M.T.3    Cone, R.D.4
  • 77
    • 0032213326 scopus 로고    scopus 로고
    • Pigmented human skin equivalent - as a model of the mechanisms of control of cell-cell and cell-matrix interactions
    • Nakazawa, K., Kalassy, M., Sahuc, F., Collombel, C., and Damour, O. (1998). Pigmented human skin equivalent - as a model of the mechanisms of control of cell-cell and cell-matrix interactions. Med. Biol. Eng. Comput. 36, 813-820.
    • (1998) Med. Biol. Eng. Comput. , vol.36 , pp. 813-820
    • Nakazawa, K.1    Kalassy, M.2    Sahuc, F.3    Collombel, C.4    Damour, O.5
  • 78
    • 0033019401 scopus 로고    scopus 로고
    • Safety evaluation of human living skin equivalents
    • Nemecek, G.M., and Dayan, A.D. (1999). Safety evaluation of human living skin equivalents. Toxicol. Pathol. 27, 101-103.
    • (1999) Toxicol. Pathol. , vol.27 , pp. 101-103
    • Nemecek, G.M.1    Dayan, A.D.2
  • 79
    • 40849118176 scopus 로고    scopus 로고
    • Diversity of fibroblasts - a review on implications for skin tissue engineering
    • Nolte, S.V., Xu, W., Rennekampff, H.O., and Rodemann, H.P. (2008). Diversity of fibroblasts - a review on implications for skin tissue engineering. Cells Tissues Organs. 187, 165-176.
    • (2008) Cells Tissues Organs. , vol.187 , pp. 165-176
    • Nolte, S.V.1    Xu, W.2    Rennekampff, H.O.3    Rodemann, H.P.4
  • 80
    • 29744440721 scopus 로고    scopus 로고
    • Construction of pigmented skin equivalent and its application to the study of congenital disorders of pigmentation
    • Okazaki, M., Suzuki, Y., Yoshimura, K., and Harii, K. (2005). Construction of pigmented skin equivalent and its application to the study of congenital disorders of pigmentation. Scand. J. Plast. Reconstr. Surg. Hand Surg. 39, 339-343.
    • (2005) Scand. J. Plast. Reconstr. Surg. Hand Surg. , vol.39 , pp. 339-343
    • Okazaki, M.1    Suzuki, Y.2    Yoshimura, K.3    Harii, K.4
  • 81
    • 23744483851 scopus 로고    scopus 로고
    • An in vitro approach to the chronological aging of skin by glycation of the collagen: the biological effect of glycation on the reconstructed skin model
    • Pageon, H., and Asselineau, D. (2005). An in vitro approach to the chronological aging of skin by glycation of the collagen: the biological effect of glycation on the reconstructed skin model. Ann. N Y Acad. Sci. 1043, 529-532.
    • (2005) Ann. N Y Acad. Sci. , vol.1043 , pp. 529-532
    • Pageon, H.1    Asselineau, D.2
  • 83
    • 77952423813 scopus 로고    scopus 로고
    • 3,3',4,4',5,5'-Hexahydroxystilbene impairs melanoma progression in a metastatic mouse model
    • Paulitschke, V., Schicher, N., Szekeres, T. et al. (2010). 3, 3', 4, 4', 5, 5'-Hexahydroxystilbene impairs melanoma progression in a metastatic mouse model. J. Invest. Dermatol. 130, 1668-1679.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 1668-1679
    • Paulitschke, V.1    Schicher, N.2    Szekeres, T.3
  • 84
    • 0031888409 scopus 로고    scopus 로고
    • New skin for old: developments in biological skin substitutes
    • Phillips, T.J. (1998). New skin for old: developments in biological skin substitutes. Arch. Dermatol. 134, 344-349.
    • (1998) Arch. Dermatol. , vol.134 , pp. 344-349
    • Phillips, T.J.1
  • 85
    • 0036853189 scopus 로고    scopus 로고
    • Skin constructs for replacement of skin tissues for in vitro testing
    • Ponec, M. (2002). Skin constructs for replacement of skin tissues for in vitro testing. Adv. Drug Deliv. Rev. 54(Suppl. 1), S19-S30.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , Issue.SUPPL. 1
    • Ponec, M.1
  • 87
    • 0036890521 scopus 로고    scopus 로고
    • Refinement of the Episkin protocol for the assessment of acute skin irritation of chemicals: follow-up to the ECVAM prevalidation study
    • Portes, P., Grandidier, M.H., Cohen, C., and Roguet, R. (2002). Refinement of the Episkin protocol for the assessment of acute skin irritation of chemicals: follow-up to the ECVAM prevalidation study. Toxicol In Vitro 16, 765-770.
    • (2002) Toxicol In Vitro , vol.16 , pp. 765-770
    • Portes, P.1    Grandidier, M.H.2    Cohen, C.3    Roguet, R.4
  • 88
    • 0020601705 scopus 로고
    • Methods for cultivation of keratinocytes with an air-liquid interface
    • Pruniéras, M., Régnier, M., and Woodley, D. (1983). Methods for cultivation of keratinocytes with an air-liquid interface. J. Invest. Dermatol. 81, 28s-33s.
    • (1983) J. Invest. Dermatol. , vol.81
    • Pruniéras, M.1    Régnier, M.2    Woodley, D.3
  • 89
    • 0346786217 scopus 로고    scopus 로고
    • Genetics of hair and skin color
    • Rees, J.L. (2003). Genetics of hair and skin color. Annu. Rev. Genet. 37, 67-90.
    • (2003) Annu. Rev. Genet. , vol.37 , pp. 67-90
    • Rees, J.L.1
  • 90
    • 0027195886 scopus 로고
    • Barrier function of human skin and human reconstructed epidermis
    • Régnier, M., Caron, D., Reichert, U., and Schaefer, H. (1993). Barrier function of human skin and human reconstructed epidermis. J. Pharm. Sci. 82, 404-407.
    • (1993) J. Pharm. Sci. , vol.82 , pp. 404-407
    • Régnier, M.1    Caron, D.2    Reichert, U.3    Schaefer, H.4
  • 91
    • 0030764790 scopus 로고    scopus 로고
    • Integration of Langerhans cells into a pigmented reconstructed human epidermis
    • Régnier, M., Staquet, M.J., Schmitt, D., and Schmidt, R. (1997). Integration of Langerhans cells into a pigmented reconstructed human epidermis. J. Invest. Dermatol. 109, 510-512.
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 510-512
    • Régnier, M.1    Staquet, M.J.2    Schmitt, D.3    Schmidt, R.4
  • 92
    • 0032213327 scopus 로고    scopus 로고
    • Reconstructed human epidermis composed of keratinocytes, melanocytes and Langerhans cells
    • Régnier, M., Patwardhan, A., Scheynius, A., and Schmidt, R. (1998). Reconstructed human epidermis composed of keratinocytes, melanocytes and Langerhans cells. Med. Biol. Eng. Comput. 36, 821-824.
    • (1998) Med. Biol. Eng. Comput. , vol.36 , pp. 821-824
    • Régnier, M.1    Patwardhan, A.2    Scheynius, A.3    Schmidt, R.4
  • 93
    • 0032927963 scopus 로고    scopus 로고
    • Potential cosmetic applications of reconstructed epidermis
    • Régnier, M., Duval, C., and Schmidt, R. (1999). Potential cosmetic applications of reconstructed epidermis. Int. J. Cosmet. Sci. 21, 51-58.
    • (1999) Int. J. Cosmet. Sci. , vol.21 , pp. 51-58
    • Régnier, M.1    Duval, C.2    Schmidt, R.3
  • 94
    • 0016729431 scopus 로고
    • Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells
    • Rheinwald, J.G., and Green, H. (1975). Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 6, 331-343.
    • (1975) Cell , vol.6 , pp. 331-343
    • Rheinwald, J.G.1    Green, H.2
  • 95
    • 0033017076 scopus 로고    scopus 로고
    • Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts
    • Schoop, V.M., Mirancea, N., and Fusenig, N.E. (1999). Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts. J. Invest. Dermatol. 112, 343-353.
    • (1999) J. Invest. Dermatol. , vol.112 , pp. 343-353
    • Schoop, V.M.1    Mirancea, N.2    Fusenig, N.E.3
  • 97
    • 0036975764 scopus 로고    scopus 로고
    • The contributions of the European cosmetics industry to the development of alternatives to animal testing: dialogue with ECVAM and future challenges
    • European Federation of the Cosmetics Industry, Steering Committee on Alternatives to Animal Testing
    • de Silva, O., and European Federation of the Cosmetics Industry, Steering Committee on Alternatives to Animal Testing (2002). The contributions of the European cosmetics industry to the development of alternatives to animal testing: dialogue with ECVAM and future challenges. Altern. Lab. Anim. 2, 189-193.
    • (2002) Altern. Lab. Anim. , vol.2 , pp. 189-193
    • de Silva, O.1
  • 98
    • 33845208108 scopus 로고    scopus 로고
    • Life isn't flat: taking cancer biology to the next dimension
    • Smalley, K.S., Lioni, M., and Herlyn, M. (2006). Life isn't flat: taking cancer biology to the next dimension. In Vitro Cell. Dev. Biol. Anim. 42, 242-247.
    • (2006) In Vitro Cell. Dev. Biol. Anim. , vol.42 , pp. 242-247
    • Smalley, K.S.1    Lioni, M.2    Herlyn, M.3
  • 99
    • 78651453140 scopus 로고    scopus 로고
    • Human keratinocytes cultured on collagen matrix used as an experimental burn model
    • Sobral, C.S., Gragnani, A., Cao, X., Morgan, J.R., and Ferreira, L.M. (2007). Human keratinocytes cultured on collagen matrix used as an experimental burn model. J Burns Wounds 7, e6.
    • (2007) J Burns Wounds , vol.7
    • Sobral, C.S.1    Gragnani, A.2    Cao, X.3    Morgan, J.R.4    Ferreira, L.M.5
  • 100
    • 44949175934 scopus 로고    scopus 로고
    • Improvement of the dermal epidermal junction in human reconstructed skin by a new c-xylopyranoside derivative
    • Sok, J., Pineau, N., Dalko-Csiba, M., Breton, L., and Bernerd, F. (2008). Improvement of the dermal epidermal junction in human reconstructed skin by a new c-xylopyranoside derivative. Eur. J. Dermatol. 18, 297-302.
    • (2008) Eur. J. Dermatol. , vol.18 , pp. 297-302
    • Sok, J.1    Pineau, N.2    Dalko-Csiba, M.3    Breton, L.4    Bernerd, F.5
  • 101
    • 70349564824 scopus 로고    scopus 로고
    • Immunoarchitectural characterization of a human skin model reconstructed in vitro
    • Souto, L.R., Vassallo, J., Rehder, J., Pinto, G.A., and Puzzi, M.B. (2009). Immunoarchitectural characterization of a human skin model reconstructed in vitro. Sao Paulo Med. J. 127(1), 28-33.
    • (2009) Sao Paulo Med. J. , vol.127 , Issue.1 , pp. 28-33
    • Souto, L.R.1    Vassallo, J.2    Rehder, J.3    Pinto, G.A.4    Puzzi, M.B.5
  • 102
    • 2342604928 scopus 로고    scopus 로고
    • Organotypic cocultures as skin equivalents: a complex and sophisticated in vitro system
    • Stark, H.J., Szabowski, A., Fusenig, N.E., and Maas-Szabowski, N. (2004a). Organotypic cocultures as skin equivalents: a complex and sophisticated in vitro system. Biol. Proc. Online 6, 55-60.
    • (2004) Biol. Proc. Online , vol.6 , pp. 55-60
    • Stark, H.J.1    Szabowski, A.2    Fusenig, N.E.3    Maas-Szabowski, N.4
  • 103
  • 105
    • 10944234560 scopus 로고    scopus 로고
    • Melanocytes and the microphthalmia transcription factor network
    • Steingrímsson, E., Copeland, N.G., and Jenkins, N.A. (2004). Melanocytes and the microphthalmia transcription factor network. Annu. Rev. Genet. 38, 365-411.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 365-411
    • Steingrímsson, E.1    Copeland, N.G.2    Jenkins, N.A.3
  • 106
    • 16644399472 scopus 로고    scopus 로고
    • Dendritic cells and their role in atopic dermatitis
    • Tiznado-Orozco, T., and Orea-Solano, M. (2004). Dendritic cells and their role in atopic dermatitis. Rev. Alerg. Mex. 51, 119-123.
    • (2004) Rev. Alerg. Mex. , vol.51 , pp. 119-123
    • Tiznado-Orozco, T.1    Orea-Solano, M.2
  • 108
    • 1642318502 scopus 로고    scopus 로고
    • In vitro skin irritation: facts and future. State of the art review of mechanisms and models
    • Welss, T., Basketter, D.A., and Schröder, K.R. (2004). In vitro skin irritation: facts and future. State of the art review of mechanisms and models. Toxicol In Vitro 18, 231-243.
    • (2004) Toxicol In Vitro , vol.18 , pp. 231-243
    • Welss, T.1    Basketter, D.A.2    Schröder, K.R.3
  • 109
    • 34447103624 scopus 로고    scopus 로고
    • The role of fibroblasts in tissue engineering and regeneration
    • Wong, T., McGrath, J.A., and Navsaria, H. (2007). The role of fibroblasts in tissue engineering and regeneration. Br. J. Dermatol. 156, 1149-1155.
    • (2007) Br. J. Dermatol. , vol.156 , pp. 1149-1155
    • Wong, T.1    McGrath, J.A.2    Navsaria, H.3
  • 110
    • 0022996472 scopus 로고
    • Different mitogenic and phenotypic responses of human breast epithelial cells grown in two versus three dimensions
    • Yang, J., Balakrishnan, A., Hamamoto, S., Beattie, C.W., Das Gupta, T.K., Wellings, S.R., and Nandi, S. (1987). Different mitogenic and phenotypic responses of human breast epithelial cells grown in two versus three dimensions. Exp. Cell Res. 167, 563-569.
    • (1987) Exp. Cell Res. , vol.167 , pp. 563-569
    • Yang, J.1    Balakrishnan, A.2    Hamamoto, S.3    Beattie, C.W.4    Das Gupta, T.K.5    Wellings, S.R.6    Nandi, S.7
  • 112
    • 67049168909 scopus 로고    scopus 로고
    • The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes
    • Yu, H., McDaid, R., Lee, J. et al. (2009). The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes. Am. J. Pathol. 174, 2367-2377.
    • (2009) Am. J. Pathol. , vol.174 , pp. 2367-2377
    • Yu, H.1    McDaid, R.2    Lee, J.3


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