Adhesion, migration and communication in melanocytes and melanoma

Pigment Cell Research

Volumn 18, Issue 3, 2005, Pages 150-159

  Haass, Nikolas K ^a   Smalley, Keiran S M ^a   Li, Ling ^a   Herlyn, Meenhard ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

Cadherins; Cell adhesion molecules; Integrins; Melanoma; Metastasis

Indexed keywords

CADHERIN; CD146 ANTIGEN; CELL ADHESION MOLECULE; DESMOGLEIN; GAP JUNCTION PROTEIN; GROWTH FACTOR; INTEGRIN; NERVE CELL ADHESION MOLECULE; P CADHERIN; PROTEIN ZO1; RECEPTOR; UNCLASSIFIED DRUG; UVOMORULIN;

APOPTOSIS; BASEMENT MEMBRANE; CANCER GROWTH; CARCINOGENESIS; CELL ADHESION; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; DOWN REGULATION; EXTRACELLULAR MATRIX; FIBROBLAST; HOMEOSTASIS; HUMAN; KERATINOCYTE; MELANOCYTE; MELANOMA; METASTASIS; NONHUMAN; PARACRINE SIGNALING; REVIEW; SIGNAL TRANSDUCTION; UPREGULATION;

CADHERINS; CELL ADHESION; CELL COMMUNICATION; CELL MOVEMENT; CELL PROLIFERATION; HUMANS; KERATINOCYTES; MELANOCYTES; MELANOMA; MODELS, BIOLOGICAL; SKIN NEOPLASMS;

EID: 19544362066     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0749.2005.00235.x     Document Type: Review

References (82)

1. Aeed, P.A., Nakajima, M., and Welch, D.R. (1988). The role of polymorphonuclear leukocytes (PMN) on the growth and metastatic potential of 13762NF mammary adenocarcinoma cells. Int. J. Cancer 42, 748-759.
2. Albelda, S.M., Mette, S.A., Elder, D.E., Stewart, R., Damjanovich, L., Herlyn, M., and Buck, C.A. (1990). Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression. Cancer Res. 50, 6757-6764.
3. Bamberger, A.M., Riethdorf, L., Nollau, P., Naumann, M., Erdmann, I., Gotze, J., Brummer, J., Schulte, H.M., Wagener, C., and Loning, T. (1998). Dysregulated expression of CD66a (BGP, C-CAM), an adhesion molecule of the CEA family, in endometrial cancer. Am. J. Pathol. 152, 1401-1406.
4. Becker, J.C., Termeer, C., Schmidt, R.E., and Brocker, E.B. (1993). Soluble intercellular adhesion molecule-1 inhibits MHC-restricted specific T cell/tumor interaction. J. Immunol 151, 7224-7232.
5. Bissell, M.J., and Radisky, D. (2001). Putting tumours in context. Nat. Rev. Cancer 1, 46-54.
6. Brooks, P.C., Stromblad, S., Sanders, L.C., von Schalscha, T.L., Aimes, R.T., Stetler-Stevenson, W.G., Quigley, J.P., and Cheresh, D.A. (1996). Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 85, 683-693.
7. Brummer, J., Ebrahimnejad, A., Flayeh, R., Schumacher, U., Loning, T., Bamberger, A.M., and Wagener, C. (2001). cis Interaction of the cell adhesion molecule CEACAM1 with integrin beta(3). Am. J. Pathol. 159, 537-546.
8. Danen, E.H., Ten Berge, P.J., Van Muijen, G.N., Van't Hof-Grootenboer, A.E., Brocker, E.B., and Ruiter, D.J. (1994). Emergence of alpha 5 beta1 fibronectin- and alpha v beta 3 vitronectin-receptor expression in melanocytic tumour progression. Histopathology 24, 249-256.
9. Degen, W.G., van Kempen, L.C., Gijzen, E.G., van Groningen, J.J., van Kooyk, Y., Bloemers, H.P., and Swart, G.W. (1998). MEMD, a new cell adhesion molecule in metastasizing human melanoma cell lines, is identical to ALCAM (activated leukocyte cell adhesion molecule). Am. J. Pathol. 152, 805-813.
10. Ebrahimnejad, A., Streichelt, T., Nollau, P., Horst, A.K., Wagener, C., Bamberger, A.M., and Brummer, J. (2004). CEACAM1 enhances invasion and migration of melanocytic and melanoma cells. Am. J. Pathol. 165, 1781-1787.
11. Felding-Habermann, B., Mueller, B.M., Romerdahl, C.A., and Cheresh, D.A. (1992). Involvement of imegrin alpha V gene expression in human melanoma tumorigenicity. J. Clin. Invest. 89, 2018-2022,
12. Filardo, E.J., Deming, S.L., and Cheresh, D.A. (1996). Regulation of cell migration by the integrin beta subunit ectodomain. J. Cell Sci. 109 (Pt 6), 1615-1622.
13. Fitzpatrick, T.B., and Breathnach, A.S. (1963). [The Epidermal Melanin Unit System]. Dermatol. Wochenschr, 147, 481-489.
14. van der Flier, A., and Sonnenberg, A. (2001). Function and interactions of integrins. Cell Tissue Res. 305, 285-298.
15. Fogel, M., Mechtersheimer, S., Huszar, M., Smirnov, A., Abu-Dahi, A., Tilgen, W., Reichrath, J., Georg, T., Altevogt, P., and Gutwein, P. (2003). L1 adhesion molecule (CD 171) in development and progression of human malignant melanoma. Cancer Lett. 189, 237-247.
16. Giavazzi, R., Chirivi, R.G., Garofaio, A., Rambaldi, A., Hemingway, I., Pigott, R., and Gearing, A.J. (1992). Soluble intercellular adhesion molecule 1 is released by human melanoma cells and is associated with tumor growth in nude mice. Cancer Res. 52, 2628-2630.
17. Haass, N.K., and Herlyn, M. (in press) Normal human melanocyte homeostasis as a paradigm for understanding melanoma J. Invest. Dermatol. Symp. Proc.
18. Haass, N.K., Smalley, K.S.M., and Herlyn, M. (2004). The role of altered cell-cell communication in melanoma progression. J. Mol. Histol. 35, 309-318.
19. Hanahan, D., and Weinberg, R.A. (2000). The hallmarks of cancer. Cell 100, 57-70.
20. Hartstein, M.E., Grove, A.S., Jr, and Woog, J.J. (1997). The role of the integrin family of adhesion molecules in the development of tumors metastatic to the orbit. Ophthal. Plast. Reconstr. Surg. 13, 227-238.
21. Hegerfeldt, Y., Tusch, M., Brocker, E.B., and Friedl, P. (2002). Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies. Cancer Res. 62, 2125-2130.
22. Hixson, D.C., and McEntire, K.D. (1989). On rat transplantable and primary hepatocellular carcinomas. Cancer Res. 105, 6788-6794,
23. Holzmann, B., Gosslar, U., and Bittner, M. (1998). Alpha 4 integrins and tumor metastasis. Curr. Top. Microbiol. Immunol. 231, 125-141.
24. Hortsch, M. (1996). The L1 family of neural cell adhesion molecules: old proteins performing new tricks. Neuron 17, 587-593.
25. Hsu, M.Y., Shih, D.T., Meier, F.E., Van Belle, P., Hsu, J.Y., Elder, D.E., Buck, C.A., and Herlyn, M. (1998). Adenoviral gene transfer of beta3 integrin subunit induces conversion from radial to vertical growth phase in primary human melanoma. Am. J. Pathol. 153, 1435-1442.
26. Hsu, M.Y., Meier, F.E., Nesbit, M., Hsu, J.Y., Van Belle, P., Elder, D.E., and Herlyn, M. (2000). E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am. J. Pathol. 156, 1515-1525.
27. Hynes, R.O. (1996). Targeted mutations in cell adhesion genes: what have we learned from them? Dev. Biol. 180, 402-412.
28. Hynes, R.O. (2002). Integrins: bidirectional, allosteric signaling machines. Cell 110, 673-687.
29. Jimbow, K., Quevedo, W.C. Jr, Fitzpatrick, T.B., and Szabo, G. (1976). Some aspects if melanin biology: 1950-1975. J. Invest. Dermatol. 67, 72-89.
30. Johnson, J.P. (1999). Cell adhesion molecules in the development and progression of malignant melanoma. Cancer Metastasis Rev. 18, 345-357.
31. Johnson, J.P., Stade, B.G., Holzmann, B., Schwable, W., and Riethmuller, G. (1989). De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis. Proc. Natl Acad. Sci. U. S. A. 86, 641-644.
32. Johnson, J.P., Rummel, M.M., Rothbacher, U., and Sers, C. (1996). MUC18: A cell adhesion molecule with a potential role in tumor growth and tumor cell dissemination. Curr. Top. Microbiol. Immunol. 213 (Pt 1), 95-105.
33. Johnson, J.P., Bar-Eli, M., Jansen, B., and Markhof, E. (1997). Melanoma progression-associated glycoprotein MUC18/MCAM mediates homotypic cell adhesion through interaction with a heterophilic ligand. Int. J. Cancer 73, 769-774.
34. van Kempen, L.C., van den Oord, J.J., van Muijen, G.N., Weidle, D.H., Bloemers, H.P., and Swart, G.W. (2000). Activated leukocyte cell adhesion molecule/CD 166, a marker of tumor progression in primary malignant melanoma of the skin. Am. J. Pathol. 156, 769-774.
35. van Kempen, L.C., Meier, F., Egeblad, M., Kersten-Niessen, M.J., Garbe, C., Weidle, U.H., Van Muijen, G.N., Herlyn, M., Bloemers, H.P., and Swart, G.W. (2004). Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis. J. Invest. Dermatol. 122, 1293-1301.
36. Kleinerman, D.I., Troncoso, P., Lin, S.H., Pisters, L.L., Sherwood, E.R., Brooks, T., von Eschenbach, A.C., and Hsieh, J.T. (1995). Consistent expression of an epithelial cell adhesion molecule (C-CAM) during human prostate development and loss of expression in prostate cancer: implication as a tumor suppressor. Cancer Res. 55, 1215-1220.
37. Kraus, A., Masat, L., and Johnson, J.P. (1997). Analysis of the expression of intercellular adhesion molecule-1 and MUC18 on benign and malignant melanocytic lesions using monoclonal antibodies directed against distinct epitopes and recognizing denatured, non-glycosylated antigen. Melanoma Res. 7(Suppl. 2), S75-S81.
38. Kuphal, S., Bauer, R., and Bosserhoff, A.K. (in press) Integrin signaling in malignant melanoma. Cancer Metastasis Rev.
39. Lehmann, J.M., Riethmuller, G., and Johnson, J.P. (1989). MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily. Proc. Natl Acad. Sci. U. S. A. 86, 9891-9895.
40. Li, G., and Herlyn, M. (2000). Dynamics of intercellular communication during, melanoma development. Mol. Med. Today 6, 163-169.
41. Li, X., Chen, B., Blystone, S.D., McHugh, K.P., Ross, F.P., and Ramos, D.M. (1998). Differential expression of alphav integrins in K1735 melanoma cells. Invasion Metastasis 18, 1-14.
42. Li, X., Regezi, J., Ross, F.P., Blystone, S., Ilic, D., Leong, S.P., and Ramos, D.M. (2001). Integrin alphavbeta3 mediates K1735 murine melanoma cell motility in vivo and in vitro. J. Cell Sci. 114, 2665-2672.
43. McGary, E.C., Lev, D.C., and Bar-Eli, M. (2002). Cellular adhesion pathways and metastatic potential of human melanoma. Cancer Biol. Ther. 1, 459-465.
44. Meier, F., Nesbit, M., Hsu, M.Y. et al. (2000). Human melanoma progression in skin reconstructs: biological significance of bFGF. Am. J. Pathol. 156, 193-200.
45. Melchiori, A., Mortarini, R., Carlone, S., Marchisio, P.C., Anichini, A., Noonan, D.M., and Albini, A. (1995). The alpha 3 beta 1 integrin is involved in melanoma cell migration and invasion. Exp. Cell Res. 219, 233-242.
46. Miele, M.E., Bennett, C.F., Miller, B.E., and Welch, D.R. (1994). Enhanced metastatic ability of TNF-alpha-treated malignant melanoma cells is reduced by intercellular adhesion molecule-1 (ICAM-1, CD54) antisense oligonucleotides. Exp. Cell Res. 214, 231-241.
47. Montgomery, A.M., Reisfeld, R.A., and Cheresh, D.A. (1994). Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc. Natl Acad. Sci. U. S. A. 91 8856-8860.
48. Montgomery, A.M., Becker, J.C., Siu, C.H., Lemmon, V.P., Cheresh, D.A., Pancook, J.D., Zhao, X., and Reisfeld, R.A. (1996). Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3. J. Cell Biol. 132, 475-485.
49. Moretti, S., Martini, L., Berti, E., Pinzi, C., and Giannotti, B. (1993). Adhesion molecule profile and malignancy of melanocytic lesions. Melanoma Res. 3, 235-239.
50. Natali, P., Nicotra, M.R., Cavaliere, R., Bigotti, A., Romano, G., Temponi, M., and Ferrone, S. (1990). Differential expression of intercellular adhesion molecule 1 in primary and metastatic melanoma lesions. Cancer Res. 50, 1271-1278.
51. Natali, P.G., Nicotra, M.R., Bartolazzi, A., Cavaliere, R., and Bigotti, A. (1993). Integrin expression in cutaneous malignant melanoma: association of the alpha 3/beta 1 heterodimer with tumor progression. Int. J. Cancer 54, 68-72.
52. Natali, P.G., Hamby, C.V., Felding-Habermann, B., Liang, B., Nicotra, M.R., Di Filippo, F., Giannarelli, D., Temponi, M., and Ferrone, S. (1997). Clinical significance of alpha(v)beta3 integrin and intercellular adhesion molecule-1 expression in cutaneous malignant melanoma lesions. Cancer Res. 57, 1554-1560.
53. Nesbit, M., and Herlyn, M. (1994). Adhesion receptors in human melanoma progression. Invasion Metastasis 14, 131-146.
54. Nikkola, J., Vihinen, P., Vlaykova, T., Hahka-Kemppinen, M., Heino, J., and Pyrhonen, S. (2004). Integrin chains beta1 and alphav as prognostic factors in human metastatic melanoma. Melanoma Res. 14, 29-37.
55. Nollau, P., Scheller, H., Kona-Horstmann, M., Ronde, S., Hagenmuller, F., Wagener, C., and Neumaier, M. (1997). Expression of CD66a (human C-CAM) and other members of the carcinoembryonic antigen gene family of adhesion molecules in human colorectal adenomas. Cancer Res. 57, 2354-2357.
56. Nolte, C., Moos, M., and Schachner, M. (1999). Immunolocalization of the neural cell adhesion molecule L1 in epithelia of rodents. Cell Tissue Res. 298, 261-273.
57. Palecek, S.P., Huttenlocher, A., Horwitz, A.F., and Lauffenburger, D.A. (1998). Physical and biochemical regulation of integrin release during rear detachment of migrating cells. J. Cell Sci. 111 (Pt 7), 929-940.
58. Palecek, S.P., Horwitz, A.F., and Lauffenburger, D.A. (1999). Kinetic model for integrin-mediated adhesion release during cell migration. Ann. Biomed. Eng. 27, 219-235.
59. Park, C.C., Bissell, M.J., and Barcellos-Hoff, M.H. (2000). The influence of the microenvironment on the malignant phenotype. Mol. Med. Today 6, 324-329.
60. Patel, D.D., Wee, S.F., Whichard, L.P., Bowen, M.A., Pesando, J.M., Aruffo, A., and Haynes, B.F. (1995). Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells. J. Exp. Med. 181, 1563-1568.
61. Petitclerc, E., Stromblad, S., von Schalscha, T.L., Mitjans, F., Piulats, J., Montgomery, A.M., Cheresh, D.A., and Brooks, P.C. (1999). Integrin alpha(v)beta3 promotes M21 melanoma growth in human skin by regulating tumor cell survival. Cancer Res. 59, 2724-2730.
62. Raucher, D., and Sheetz, M.P. (2000). Cell spreading and lamellipodial extension rate is regulated by membrane tension. J. Cell Biol. 148, 127-136.
63. Riethdorf, L., Lisboa, B.W., Henkel, U., Naumann, M., Wagener, C., and Loning, T. (1997). Differential expression of CD66a (BGP), a cell adhesion molecule of the carcinoembryonic antigen family, in benign, premalignant, and malignant lesions of the human mammary gland. J. Histochem. Cytochem. 45, 957-963.
64. Satyamoorthy, K., Muyrers, J., Meier, F., Patel, D., and Herlyn, M. (2001). Mel-CAM-specific genetic suppressor elements inhibit melanoma growth and invasion through loss of gap functional communication. Oncogene 20, 4676-4684.
65. Schadendorf, D., Gawlik, C., Haney, U., Ostmeier, H., Suter, L., and Czarnetzki, B.M. (1993). Tumour progression and metastatic behaviour in vivo correlates with integrin expression on melanocytic tumours. J. Pathol. 170, 429-434.
66. Schadendorf, D., Heidel, J., Gawlik, C., Suter, L., and Czarnetzki, B.M. (1995). Association with clinical outcome of expression of VLA-4 in primary cutaneous malignant melanoma as well as P-selectin and E-selectin on intratumoral vessels. J. Natl Cancer Inst. 87, 366-371.
67. Schlagbauer-Wadl, H., Jansen, B., Muller, M., Polterauer, P., Wolff, K., Eichler, H.G., Pehamberger, H., Konak, E., and Johnson, J.P. (1999). Influence of MUC18/MCAM/CD146 expression on human melanoma growth and metastasis in SCID mice. Int. J. Cancer 81, 951-955.
68. Schumacher, D., and Schaumburg-Lever, G. (1999). Ultrastructural localization of alpha-3 integrin subunit in malignant melanoma and adjacent epidermis. J. Cutan. Pathol. 26, 321-326.
69. Shin, I.M., Elder, D.E., Speicher, D., Johnson, J.P., and Herlyn, M. (1994). Isolation and functional characterization of the A32 melanoma-associated antigen. Cancer Res. 54, 2514-2520.
70. Shih, I.M., Speicher, D., Hsu, M.Y., Levine, E., and Herlyn, M. (1997a). Melanoma cell-cell interactions are mediated through heterophilic Mel-CAM/ligand adhesion. Cancer Res. 57, 3835-3840.
71. Shih, L.M., Hsu, M.Y., Palazzo, J.P., and Herlyn, M. (1997b). The cell-cell adhesion receptor Mel-CAM acts as a tumor suppressor in breast carcinoma. Am. J. Pathol. 151, 745-751.
72. Sienel, W., Dango, S., Woelfle, U., Morresi-Hauf, A., Wagener, C., Brummer, J., Mutschier, W., Passlick, B., and Pantel, K. (2003). Promotes progression of non-small cell lung cancer. Clin. Cancer Res. 1, 2260-2266.
73. van de Stolpe, A., and van der Saag, P.T. (1996). Intercellular adhesion molecule-1. J. Mol. Med. 74, 13-33.
74. Swart, G.W., Lunter, P.C., van Kilsdonk, J.W.J., and van Kempen, L.C.L.T. (in press) Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166): Signaling at the Divide of Melanoma Cell Clustering and Cell Migration? Cancer Metastasis Rev.
75. Thies, A., Moll, I., Berger, J., Wagener, C., Brummer, J., Schulze, H.J., Brunner, G., and Schumacher, U. (2002a). CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease. J. Clin. Oncol. 20, 2530-2536.
76. Thies, A., Schachner, M., Moll, I., Berger, J., Schulze, H.J., Brunner, G., and Schumacher, U. (2002b). Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma. Eur. J. Cancer 38, 1708-1716.
77. Van Belle, P.A., Elenitsas, R., Satyamoorthy, K. et al. (1999). Progression-related expression of beta3 integrin in melanomas and nevi. Hum. Pathol. 30, 562-567.
78. Voura, E.B., Ramjeeslngh, R.A., Montgomery, A.M., and Siu, C.H. (2001). Involvement of integrin alpha(v)beta(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells. Mol. Biol. Cell 12, 2699-2710.
79. Xie, S., Luca, M., Huang, S., Gutman, M., Reich, R., Johnson, J.P., and Bar-Eli, M. (1997). Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis. Cancer Res. 57, 2295-2303.
80. Yoshinaga, I.G., Vink, J., Dekker, S.K., Mihm, M.C. Jr, and Byers, H.R. (1993). Role of alpha 3 beta 1 and alpha 2 beta 1 integrins in melanoma cell migration. Melanoma Res. 3, 435-441.
81. Zhu, N., Eves, P.C., Katerinaki, E., Szabo, M., Morandini, R., Ghanem, G., Lorigan, P., MacNeil, S., and Haycock, J.W. (2002). Melanoma cell attachment, invasion, and integrin expression is upregulated by tumor necrosis factor alpha and suppressed by alpha melanocyte stimulating hormone. J. Invest. Dermatol. 119, 1165-1171.
82. Ziober, B.L., Chen, Y.Q., Ramos, D.M., Waleh, N., and Kramer, R.H. (1999). Expression of the alpha7beta1 laminin receptor suppresses melanoma growth and metastatic potential. Cell Growth Differ. 10, 479-490.