A feasibility study developing an integrated testing strategy assessing skin irritation potential of chemicals

Toxicology Letters

Volumn 180, Issue 1, 2008, Pages 9-20

  Hoffmann, Sebastian ^a   Saliner, Ana Gallegos ^a,b   Patlewicz, Grace ^a   Eskes, Chantra ^a   Zuang, Valerie ^a   Worth, Andrew P ^a  

^a JOINT RESEARCH CENTRE   (Italy)

^b UNIVERSITY OF GIRONA   (Spain)

Author keywords

Draize test; In silico; In vitro; Integrated testing strategy; Skin irritation

Indexed keywords

TOXIC SUBSTANCE;

ARTICLE; COMPUTER MODEL; FEASIBILITY STUDY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SKIN IRRITATION;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; EPIDERMIS; FEASIBILITY STUDIES; HUMANS; IRRITANTS; MODELS, ANIMAL; PREDICTIVE VALUE OF TESTS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SKIN IRRITANCY TESTS; XENOBIOTICS;

ANIMALIA;

EID: 47049123953     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.05.004     Document Type: Article

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