Chemical blockage of the proteasome inhibitory function of bortezomib: Impact on tumor cell death

Journal of Biological Chemistry

Volumn 281, Issue 2, 2006, Pages 1107-1118

  Fernández, Yolanda ^a,b   Miller, Thomas P ^a,b   Denoyelle, Christophe ^a,b   Esteban, Jose A ^c   Tang, Wen Hua ^a,b   Bengston, Audrey L ^a,b   Soengas, María S ^a,b,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; BIOCHEMISTRY; CELL CULTURE; OXYGEN; POLYMERS; REACTION KINETICS; TUMORS;

ANTI-CANCER AGENT; BORTEZOMIB; PROTEASOME; TUMOR CELLS;

PROTEINS;

ACETYLCYSTEINE; ALPHA TOCOPHEROL; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BORTEZOMIB; REACTIVE OXYGEN METABOLITE; TACROLIMUS; TIRON; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; BORONIC ACID DERIVATIVE; FREE RADICAL; LEUPEPTIN; PROTEASOME; PROTEINASE INHIBITOR; PYRAZINE DERIVATIVE;

ARTICLE; BREAST CARCINOMA; CANCER CELL; CELL DEATH; CYTOTOXICITY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; MELANOMA CELL; PRIORITY JOURNAL; T CELL LYMPHOMA; BINDING COMPETITION; BIOLOGICAL MODEL; BREAST TUMOR; CELL LINE; CELL MEMBRANE POTENTIAL; CELL SURVIVAL; CHEMISTRY; FIBROBLAST; IMMUNOBLOTTING; KINETICS; MELANOCYTE; MELANOMA; METABOLISM; PATHOLOGY; SKIN; TIME; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; BINDING, COMPETITIVE; BORONIC ACIDS; BREAST NEOPLASMS; CELL DEATH; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DRUG ANTAGONISM; FIBROBLASTS; FREE RADICALS; HUMANS; IMMUNOBLOTTING; KINETICS; LEUPEPTINS; MELANOCYTES; MELANOMA; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRAZINES; REACTIVE OXYGEN SPECIES; SKIN; TIME FACTORS; TIRON;

EID: 33644871517     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511607200     Document Type: Article

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