Probing the influence of an allylic methyl group in zearalenone analogues on binding to Hsp90

Chemistry - A European Journal

Volumn 16, Issue 48, 2010, Pages 14469-14478

  Rink, Christian ^a   Sasse, Florenz ^b   Zubrienä , Asta ^c   Matulis, Daumantas ^c   Maier, Martin E ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c VILNIUS UNIVERSITY   (Lithuania)

Author keywords

asymmetric synthesis; Hsp90; macrolactonization; natural products; zearalenone

Indexed keywords

ASYMMETRIC SYNTHESIS; HSP90; MACROLACTONIZATION; NATURAL PRODUCTS; ZEARALENONE;

ALDEHYDES; CARBOXYLATION; CELL CULTURE; DISSOCIATION; FUNCTIONAL GROUPS; KETONES; PHENOLS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

GROUP TECHNOLOGY;

DRUG DERIVATIVE; HEAT SHOCK PROTEIN 90; LACTONE; ZEARALENONE;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; FIBROBLAST; IC 50; METABOLISM; MOUSE; STEREOISOMERISM; SYNTHESIS;

ANIMALS; FIBROBLASTS; HSP90 HEAT-SHOCK PROTEINS; INHIBITORY CONCENTRATION 50; LACTONES; MICE; MOLECULAR STRUCTURE; STEREOISOMERISM; ZEARALENONE;

EID: 78651257758     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201001752     Document Type: Article

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