Radester, a novel inhibitor of the Hsp90 protein folding machinery

Organic Letters

Volumn 7, Issue 11, 2005, Pages 2157-2160

  Shen, Gang ^a   Blagg, Brian S J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTER DERIVATIVE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; HYDROQUINONE; RADESTER; RADICICOL; RAF PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN MCF 7; CHEMICAL COMPOSITION; CORRELATION ANALYSIS; CYTOTOXICITY; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN FOLDING;

ANTINEOPLASTIC AGENTS; BENZENE DERIVATIVES; BENZOQUINONES; DRUG SCREENING ASSAYS, ANTITUMOR; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; LACTAMS, MACROCYCLIC; OXIDATION-REDUCTION; PHENOLS; PYRAZOLES; QUINONES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 20444465254     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol050580a     Document Type: Article

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