Total synthesis and immunosuppressive activity of (-)-pateamine A and related compounds: Implementation of a β-lactam-based macrocyclization

Journal of the American Chemical Society

Volumn 120, Issue 47, 1998, Pages 12237-12254

  Romo, Daniel ^a   Rzasa, Robert M ^a   Shea, Helene A ^a   Park, Kaapjoo ^a   Langenhan, Joseph M ^a   Sun, Luo ^b   Akhiezer, Alexander ^b   Liu, Jun O ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; MACROLIDE; NATURAL PRODUCT; PATEAMINE A; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG ISOLATION; DRUG MECHANISM; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LEUKEMIA CELL LINE; SPONGE (PORIFERA); STEREOCHEMISTRY; T LYMPHOCYTE ACTIVATION;

EID: 0032477277     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja981846u     Document Type: Article

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