Propionate analogues of zearalenone bind to Hsp90

ChemBioChem

Volumn 10, Issue 13, 2009, Pages 2203-2212

  Ugele, Markus ^a   Sasse, Florenz ^b   Knapp, Stefan ^c   Fedorov, Oleg ^c   Zubriene, Asta ^d   Matulis, Daumantas ^d   Maier, Martin E ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d VILNIUS UNIVERSITY   (Lithuania)

Author keywords

Antitumor agents; Biological activity; Macrolactones; Natural product analogues; Ring closing metathesis

Indexed keywords

17 DEMETHOXY 17 (2 DIMETHYLAMINOETHYLAMINO)GELDANAMYCIN; 2,4 DIMETHOXY 6 VINYLBENZOIC ACID; 3 HYDROXYBUTYRIC ACID; ACETIC ACID; ACETOACETIC ACID DERIVATIVE; ALKENE DERIVATIVE; ALKYNE; BENZOFURAN DERIVATIVE; BENZOIC ACID DERIVATIVE; BUTYRIC ACID DERIVATIVE; CURVULARIN; CYCLOPROPARADICICOL; DERRUBONE; DIBROMOALKENE; ESTER; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; ISOXAZOLE; LACTONE DERIVATIVE; MACROLACTONE; METHYL 2 METHYL 3 (TRIISOPROPYLSILOXY)BUTANOATE; METHYL 3 HYDROXY 2 METHYLBUTANOATE; NATURAL PRODUCT; PROPIONIC ACID; RADAMIDE; RADESTER; RADICICOL; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZEARALENONE; ZEARALENONE DERIVATIVE;

ALKYLATION; ANIMAL CELL; ARTICLE; CYTOTOXICITY; DEPROTECTION REACTION; DRUG STRUCTURE; ENANTIOMER; FIBROBLAST CULTURE; HYDROGENATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RING CLOSING METATHESIS; SYNTHESIS;

ANIMALS; CELL LINE; HSP90 HEAT-SHOCK PROTEINS; HYDROGENATION; LIGANDS; MACROLIDES; MICE; PROPIONATES; PROTEIN BINDING; STEREOISOMERISM; ZEARALENONE;

EID: 70349392063     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200900109     Document Type: Article

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