Evidence for GnRH regulation by leptin: Leptin administration prevents reduced pulsatile LH secretion during fasting

Neuroendocrinology

Volumn 67, Issue 6, 1998, Pages 370-376

  Nagatani, Shoji ^a   Guthikonda, Padma ^a   Thompson, Robert C ^a   Tsukamura, Hiroko ^b   Maeda, Kei Ichiro ^b   Foster, Douglas L ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

Fasting; Gonadotropin releasing hormone; Gonadotropins; Leptin

Indexed keywords

ESTROGEN; GONADORELIN; INSULIN; LEPTIN; LUTEINIZING HORMONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; INSULIN BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; NEGATIVE FEEDBACK; NONHUMAN; NUTRITION; OVARIECTOMY; PRIORITY JOURNAL; PULSATILE HORMONE RELEASE; RAT;

ANIMALS; ESTRADIOL; FASTING; FEMALE; GONADOTROPIN-RELEASING HORMONE; INSULIN; LEPTIN; LUTEINIZING HORMONE; OVARIECTOMY; PERIODICITY; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031813699     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054335     Document Type: Article

References (36)

1. Bronson FH: Environmental regulation: Some general principles; in Bronson FH (ed): Mammalian Reproductive Biology. Chicago, University of Chicago Press, 1989, pp 7-27.
2. Cagampang FRA, Maeda K-I, Yokoyama A, Ota K: Effect of food deprivation on the pulsatile LH release in the cycling and ovariectomized female rat. Horm Metab Res 1990;22: 269-272.
3. Foster DL, Bucholtz DC, Herbosa CG: Metabolic signals and the timing of puberty in sheep; in Plant TM, Lee PA (eds): The Neurobiology of Puberty. Bristol, Journal of Endocrinology Ltd, 1995, pp 243-257.
4. Schreihofer DA, Amico JA, Cameron JL: Reversal of fasting-induced suppression of luteinizing hormone (LH) secretion in male rhesus monkeys by intragastric nutrient infusion: Evidence for rapid stimulation of LH by nutritional signals. Endocrinology 1993;132:1890-1897.
5. Wade GN, Schneider JE, Li H-Y: Control of fertility by metabolic cues. Am J Physiol 1996; 270:E1-E19.
6. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-432.
7. Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS: Role of leptin in the neuroendocrine response to fasting. Nature 1996;382:250-252.
8. Cagampang FRA, Maeda K-I, Tsukamura H, Ohkura S, Ota K: Involvement of ovarian steroids and endogenous opioids in the fasting-induced suppression of pulsatile LH release in ovariectomized rats. J Endocrinol 1991;129: 321-328.
9. Weick RF, Noh KA: Inhibitory effects of estrogen and progesterone on several parameters of pulsatile LH release in the ovariectomized rat. Neuroendocrinology 1984;38:351-356.
10. Leipheimer RE, Bona-Gallo A, Gallo RV: Influence of estradiol and progesterone on pulsatile LH secretion in 8-day ovariectomized rats. Neuroendocrinology 1986;43:300-307.
11. Chehab FF, Mounzih K, Lu R, Lim ME: Early onset of reproductive function in normal female mice treated with leptin. Science 1997; 275:88-90.
12. Veldhuis JD, Johnson ML: Cluster analysis: A simple, versatile, and robust algorithm for endocrine pulse detection. Am J Physiol 1986; 250:E486-E493.
13. Bucholtz DC, Vidwans NM, Herbosa CG, Schillo KK, Foster DL: Metabolic interfaces between growth and reproduction. V. Pulsatile LH secretion is dependent upon glucose availability. Endocrinology 1996;137:601-607.
14. Barash IA, Cheung CC, Weigle DS, Ren H, Kabigting EB, Kuijper JL, Clifton DK, Steiner RA: Leptin is a metabolic signal to the reproductive system. Endocrinology 1996;137: 3144-3147.
15. Chehab FF, Lim ME, Ronghue L: Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet 1996;12:318-320.
16. Mounzih K, Lu R, Chehab FF: Leptin treatment rescues the sterility of genetically obese ob/ob males. Endocrinology 1997;138:1190-1193.
17. Cheung CC, Thornton JE, Kuijper JL, Weigle DS, Clifton DK, Steiner RA: Leptin is a metabolic gate for the onset of puberty in the female rat. Endocrinology 1997;138:855-858.
18. Zamorano PL, Mahesh VB, De Sevilla LM, Chorich LP, Bhat GK, Brann DW: Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat. Neuroendocrinology 1997;65:223-228.
19. Mangels RA, Jetton AE, Powers JB, Wade GN: Food deprivation and the facilitatory effects of estrogen in female hamsters: The LH surge and locomotor activity. Physiol Behav 1996;60: 837-843.
20. Maeda K-I, Nagatani S, Estacio MA, Tsukamura H: Novel estrogen feedback sites associated with stress-induced suppression of luteinizing hormone secretion in female rats. Cell Mol Neurobiol 1996;16:311-324.
21. Evans NP, Dahl GE, Glover BH, Karsch FJ: Central regulation of pulsatile gonadotropin-releasing hormone (GnRH) secretion by estradiol during the period leading up to the preovulatory GnRH surge in the ewe. Endocrinology 1994;134:1806-1811.
22. Bennett PA, Lindell K, Karlsson C, Carlsson LMS, Carlsson B, Robinson ICAF: Leptin receptor (Ob-R) gene expression and regulation in the rat (abstract OR22-2). 79th Annu Meet Endocrine Soc, Minneapolis 1997.
23. Mercer JG, Moar KM, Hoggard N: Localization of leptin receptor (Ob-R) messenger ribonucleic acid in the rodent hindbrain. Endocrinology 1998;139:29-34.
24. Yu WH, Kimura M, Walczewska A, Karanth S, McCann SM: Role of leptin in hypothalamic-pituitary function. Proc Natl Acad Sci USA 1997;94:1023-1028.
25. Nagatani S, Bucholtz DC, Murahashi K, Estacio MAC, Tsukamura H, Foster DL, Maeda K-I: Reduction of glucose availability suppresses pulsatile LH release in female and male rats. Endocrinology 1996;137:1166-1170.
26. Murahashi K, Bucholtz DC, Nagatani S, Tsukahara S, Tsukamura H, Foster DL, Maeda K-I: Suppression of LH pulses by restriction of glucose availability is mediated by sensors in the brain stem. Endocrinology 1996;137:1171-1176.
27. Dong Q, Lazarus RM, Wong LS, Vellios M, Handelsman DJ: Pulsatile LH secretion in streptozotocin-induced diabetes in the rat. J Endocrinol 1991;131:49-55.
28. Kamohara S, Burcelin R, Halaas JL, Friedman JM, Charron MJ: Acute stimulation of glucose metabolism in mice by leptin treatment. Nature 1997;389:374-377.
29. Sivitz WI, Walsh SA, Morgan DA, Thomas MJ, Haynes WG: Effects of leptin on insulin sensitivity in normal rats. Endocrinology 1997; 138:3395-3401.
30. Cagampang FRA, Maeda K-I, Ota K: Involvement of the gastric vagal nerve in the suppression of pulsatile luteinizing hormone release during acute fasting in rats. Endocrinology 1992;130:3003-3006.
31. Maeda K-I, Cagampang ERA, Coen CW, Tsukamura H: Involvement of the catecholaminergic input to the paraventricular nucleus and of corticotropin-releasing hormone in the fasting-induced suppression of luteinizing hormone release in female rats. Endocrinology 1994;134: 1718-1722.
32. Heiman ML, Ahima RS, Craft LS, Schoner B, Stephens TW, Flier JS: Leptin inhibition of the hypothalamic-pituitary-adrenal axis in response to stress. Endocrinology 1997;138: 3859-3863.
33. Schneider JE, Goldman MD, Tang S, Bean B: Leptin, metabolic fuels and reproduction in Syrian hamsters (abstract 166.15). 27th Annu Meet Soc for Neuroscience, New Orleans 1997.
34. Lumpkin MD, De Paolo LV, Negro-Vilar A: Pulsatile release of follicle-stimulating hormone in ovariectomized rats is inhibited by porcine follicular fluid (inhibin). Endocrinology 1984;114:201-206.
35. Armario A, Gavalda A, Marti J: Comparison of the behavioral and endocrine response to forced swimming stress in five inbred strains of rats. Psychoneuroendocrinology 1995;20:879-890.
36. Gomez F, Lahmame A, De Kloet ER, Armario A: Hypothalamic-pituitary-adrenal response to chronic stress in five inbred rat strains: Differential responses are mainly located at the adrenocortical level. Neuroendocrinology 1996;63: 327-337.