Trans-activation between 7TM domains: Implication in heterodimeric GABA B receptor activation

EMBO Journal

Volumn 30, Issue 1, 2011, Pages 32-42

  Monnier, Carine ^a,b   Tu, Haijun ^a,b   Bourrier, Emmanuel ^c   Vol, Claire ^a,b   Lamarque, Laurent ^c   Trinquet, Eric ^c   Pin, Jean Philippe ^a,b   Rondard, Philippe ^a,b  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b UNIV MONTPELLIER   (France)

^c Cisbio Bioassays   (France)

Author keywords

allosteric modulators; anxiety; class C GPCRs; drug addiction; trans activation

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B1 RECEPTOR; 4 AMINOBUTYRIC ACID B2 RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; SEVEN TRANSMEMBRANE PROTEIN; UNCLASSIFIED DRUG;

AGONIST; ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOTECHNOLOGY; CELL COMMUNICATION; CELL SURFACE; CONTROLLED STUDY; CROSS COUPLING REACTION; DIMERIZATION; EXTRACELLULAR MATRIX; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE MUTATION; HETERODIMERIZATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SNAP TAG TECHNOLOGY; TRANSACTIVATION; WILD TYPE;

EID: 78650920787     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.270     Document Type: Article

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