A novel bioassay for detecting GPCR heterodimerization: Transactivation of beta 2 adrenergic receptor by bradykinin receptor

Journal of Biomolecular Screening

Volumn 15, Issue 3, 2010, Pages 251-260

  Haack, Karla K V ^a,d   Tougas, Michelle R ^a   Jones, Kymry T ^a   El Dahr, Samir S ^b   Radhakrishna, Harish ^c   McCarty, Nael A ^a,d,e  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c The Coca Cola Company   (United States)

^d EMORY UNIVERSITY   (United States)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Beta 2 adrenergic receptor; Bradykinin type 2 receptor; Electrophysiology; Heterodimerization; Transactivation

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; BETA 2 ADRENERGIC RECEPTOR; BISINDOLYLMALEIMIDE; BRADYKININ RECEPTOR; BUCLADESINE; CHLORIDE CHANNEL; COMPLEMENTARY DNA; COMPLEMENTARY RNA; CYCLIC AMP; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; ICATIBANT; PROPRANOLOL; SEROTONIN 2C RECEPTOR; TERBUTALINE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; BIOASSAY; CONTROLLED STUDY; DIMERIZATION; DOSE RESPONSE; ENZYME IMMUNOASSAY; IMMUNOPRECIPITATION; MEMBRANE ELECTROPHYSIOLOGY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ANIMALS; BIOLOGICAL ASSAY; CHO CELLS; CRICETINAE; CRICETULUS; PC12 CELLS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RATS; RECEPTOR CROSS-TALK; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, BRADYKININ; SIGNAL TRANSDUCTION; TERBUTALINE; TRANSCRIPTIONAL ACTIVATION; XENOPUS;

VATES;

EID: 77949361470     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057109360254     Document Type: Article

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