-
1
-
-
0025783336
-
Recruitment of new osteoblasts and osteoclasts is the earliest critical event in the pathogenesis of human multiple myeloma
-
Bataille R, Chappard D, Marcelli C, Dessauw P, Baldet P, et al. (1991) Recruitment of new osteoblasts and osteoclasts is the earliest critical event in the pathogenesis of human multiple myeloma. J Clin Invest 88: 62-66.
-
(1991)
J Clin Invest
, vol.88
, pp. 62-66
-
-
Bataille, R.1
Chappard, D.2
Marcelli, C.3
Dessauw, P.4
Baldet, P.5
-
2
-
-
1542330894
-
Pathogenesis of myeloma bone disease
-
Roodman GD (2004) Pathogenesis of myeloma bone disease. Blood Cells Mol Dis 32: 290-292.
-
(2004)
Blood Cells Mol Dis
, vol.32
, pp. 290-292
-
-
Roodman, G.D.1
-
3
-
-
77950836069
-
Advances in the understanding of myeloma bone disease and tumour growth
-
Yaccoby S (2010) Advances in the understanding of myeloma bone disease and tumour growth. Br J Haematol 149: 311-321.
-
(2010)
Br J Haematol
, vol.149
, pp. 311-321
-
-
Yaccoby, S.1
-
4
-
-
33644841755
-
Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors
-
Bamias A, Kastritis E, Bamia C, Moulopoulos LA, Melakopoulos I, et al. (2005) Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: incidence and risk factors. J Clin Oncol 23: 8580-8587.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8580-8587
-
-
Bamias, A.1
Kastritis, E.2
Bamia, C.3
Moulopoulos, L.A.4
Melakopoulos, I.5
-
5
-
-
0035463593
-
Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: A phase III, double-blind, comparative trial
-
Rosen LS, Gordon D, Kaminski M, Howell A, Belch A, et al. (2001) Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: a phase III, double-blind, comparative trial. Cancer J 7: 377-387.
-
(2001)
Cancer J
, vol.7
, pp. 377-387
-
-
Rosen, L.S.1
Gordon, D.2
Kaminski, M.3
Howell, A.4
Belch, A.5
-
6
-
-
24644479228
-
Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid
-
Coleman RE, Major P, Lipton A, Brown JE, Lee KA, et al. (2005) Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid. J Clin Oncol 23: 4925-4935.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4925-4935
-
-
Coleman, R.E.1
Major, P.2
Lipton, A.3
Brown, J.E.4
Lee, K.A.5
-
7
-
-
33751164196
-
Maintenance therapy with thalidomide improves survival in patients with multiple myeloma
-
Attal M, Harousseau JL, Leyvraz S, Doyen C, Hulin C, et al. (2006) Maintenance therapy with thalidomide improves survival in patients with multiple myeloma. Blood 108: 3289-3294.
-
(2006)
Blood
, vol.108
, pp. 3289-3294
-
-
Attal, M.1
Harousseau, J.L.2
Leyvraz, S.3
Doyen, C.4
Hulin, C.5
-
8
-
-
33645979662
-
Role of osteoblast suppression in multiple myeloma
-
Stewart JP, Shaughnessy JD, Jr. (2006) Role of osteoblast suppression in multiple myeloma. J Cell Biochem 98: 1-13.
-
(2006)
J Cell Biochem
, vol.98
, pp. 1-13
-
-
Stewart, J.P.1
Shaughnessy Jr., J.D.2
-
9
-
-
33751193178
-
Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition
-
Giuliani N, Rizzoli V, Roodman GD (2006) Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition. Blood 108: 3992-3996.
-
(2006)
Blood
, vol.108
, pp. 3992-3996
-
-
Giuliani, N.1
Rizzoli, V.2
Roodman, G.D.3
-
10
-
-
43149089554
-
The pathogenesis of the bone disease of multiple myeloma
-
Edwards CM, Zhuang J, Mundy GR (2008) The pathogenesis of the bone disease of multiple myeloma. Bone 42: 1007-1013.
-
(2008)
Bone
, vol.42
, pp. 1007-1013
-
-
Edwards, C.M.1
Zhuang, J.2
Mundy, G.R.3
-
11
-
-
76349110797
-
Osteoblastogenesis and tumor growth in myeloma
-
Yaccoby S (2009) Osteoblastogenesis and tumor growth in myeloma. Leuk Lymphoma 51: 213-220.
-
(2009)
Leuk Lymphoma
, vol.51
, pp. 213-220
-
-
Yaccoby, S.1
-
12
-
-
1542720384
-
Cancer and the microenvironment: Myeloma-osteoclast interactions as a model
-
Yaccoby S, Wezeman MJ, Henderson A, Cottler-Fox M, Yi Q, Barlogie B, et al. (2004) Cancer and the microenvironment: myeloma-osteoclast interactions as a model. Cancer Res 64: 2016-2023.
-
(2004)
Cancer Res
, vol.64
, pp. 2016-2023
-
-
Yaccoby, S.1
Wezeman, M.J.2
Henderson, A.3
Cottler-Fox, M.4
Yi, Q.5
Barlogie, B.6
-
13
-
-
27744526844
-
The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype
-
Yaccoby S (2005) The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype. Clin Cancer Res 11: 7599-7606.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7599-7606
-
-
Yaccoby, S.1
-
14
-
-
4944230728
-
Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: A vicious cycle between bone destruction and myeloma expansion
-
Abe M, Hiura K, Wilde J, Shioyasono A, Moriyama K, et al. (2004) Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion. Blood 104: 2484- 2491.
-
(2004)
Blood 104: 2484-
, pp. 2491
-
-
Abe, M.1
Hiura, K.2
Wilde, J.3
Shioyasono, A.4
Moriyama, K.5
-
15
-
-
33644558753
-
Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse model
-
Yaccoby S, Wezeman MJ, Zangari M, Walker R, Cottler-Fox M, et al. (2006) Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse model. Haematologica 91: 192-199.
-
(2006)
Haematologica
, vol.91
, pp. 192-199
-
-
Yaccoby, S.1
Wezeman, M.J.2
Zangari, M.3
Walker, R.4
Cottler-Fox, M.5
-
16
-
-
33847397091
-
Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo
-
Yaccoby S, Ling W, Zhan F, Walker R, Barlogie B, et al. (2007) Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo. Blood 109: 2106-2111.
-
(2007)
Blood
, vol.109
, pp. 2106-2111
-
-
Yaccoby, S.1
Ling, W.2
Zhan, F.3
Walker, R.4
Barlogie, B.5
-
17
-
-
41949093576
-
Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo
-
Edwards CM, Edwards JR, Lwin ST, Esparza J, Oyajobi BO, et al. (2008) Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo. Blood 111: 2833-2842.
-
(2008)
Blood
, vol.111
, pp. 2833-2842
-
-
Edwards, C.M.1
Edwards, J.R.2
Lwin, S.T.3
Esparza, J.4
Oyajobi, B.O.5
-
18
-
-
47649120741
-
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth
-
Qiang YW, Shaughnessy JD, Jr., Yaccoby S (2008) Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth. Blood 112: 374-382.
-
(2008)
Blood
, vol.112
, pp. 374-382
-
-
Qiang, Y.W.1
Shaughnessy Jr., J.D.2
Yaccoby, S.3
-
19
-
-
0027716654
-
Anabolic actions of parathyroid hormone on bone
-
Dempster DW, Cosman F, Parisien M, Shen V, Lindsay R (1993) Anabolic actions of parathyroid hormone on bone. Endocr Rev 14: 690-709.
-
(1993)
Endocr Rev
, vol.14
, pp. 690-709
-
-
Dempster, D.W.1
Cosman, F.2
Parisien, M.3
Shen, V.4
Lindsay, R.5
-
20
-
-
0032746174
-
Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone
-
Jilka RL, Weinstein RS, Bellido T, Roberson P, Parfitt AM, et al. (1999) Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone. J Clin Invest 104: 439-446.
-
(1999)
J Clin Invest
, vol.104
, pp. 439-446
-
-
Jilka, R.L.1
Weinstein, R.S.2
Bellido, T.3
Roberson, P.4
Parfitt, A.M.5
-
21
-
-
0035837553
-
Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
-
Neer RM, Arnaud CD, Zanchetta JR, Prince R, Gaich GA, et al. (2001) Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 344: 1434-1441.
-
(2001)
N Engl J Med
, vol.344
, pp. 1434-1441
-
-
Neer, R.M.1
Arnaud, C.D.2
Zanchetta, J.R.3
Prince, R.4
Gaich, G.A.5
-
22
-
-
0141796739
-
The effects of parathyroid hormone, alendronate, or both in men with osteoporosis
-
Finkelstein JS, Hayes A, Hunzelman JL, Wyland JJ, Lee H, et al. (2003) The effects of parathyroid hormone, alendronate, or both in men with osteoporosis. N Engl J Med 349: 1216-1226.
-
(2003)
N Engl J Med
, vol.349
, pp. 1216-1226
-
-
Finkelstein, J.S.1
Hayes, A.2
Hunzelman, J.L.3
Wyland, J.J.4
Lee, H.5
-
23
-
-
34248577022
-
Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
-
Jilka RL (2007) Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone 40: 1434-1446.
-
(2007)
Bone
, vol.40
, pp. 1434-1446
-
-
Jilka, R.L.1
-
24
-
-
29244446792
-
Wnt Proteins Prevent Apoptosis of Both Uncommitted Osteoblast Progenitors and Differentiated Osteoblasts by {beta}-Catenin-dependent and -independent Signaling Cascades Involving Src/ERK and Phosphatidylinositol 3-Kinase/AKT
-
Almeida M, Han L, Bellido T, Manolagas SC, Kousteni S (2005) Wnt Proteins Prevent Apoptosis of Both Uncommitted Osteoblast Progenitors and Differentiated Osteoblasts by {beta}-Catenin-dependent and -independent Signaling Cascades Involving Src/ERK and Phosphatidylinositol 3-Kinase/AKT. J Biol Chem 280: 41342-41351.
-
(2005)
J Biol Chem
, vol.280
, pp. 41342-41351
-
-
Almeida, M.1
Han, L.2
Bellido, T.3
Manolagas, S.C.4
Kousteni, S.5
-
25
-
-
26844521277
-
Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis
-
Bellido T, Ali AA, Gubrij I, Plotkin LI, Fu Q, et al. (2005) Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 146: 4577-4583.
-
(2005)
Endocrinology
, vol.146
, pp. 4577-4583
-
-
Bellido, T.1
Ali, A.A.2
Gubrij, I.3
Plotkin, L.I.4
Fu, Q.5
-
26
-
-
75149150831
-
Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation
-
Guo J, Liu M, Yang D, Bouxsein ML, Saito H, et al. (2010) Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation. Cell Metab 11: 161-171.
-
(2010)
Cell Metab
, vol.11
, pp. 161-171
-
-
Guo, J.1
Liu, M.2
Yang, D.3
Bouxsein, M.L.4
Saito, H.5
-
27
-
-
21844467220
-
SOST is a target gene for PTH in bone
-
Keller H, Kneissel M (2005) SOST is a target gene for PTH in bone. Bone 37: 148-158.
-
(2005)
Bone
, vol.37
, pp. 148-158
-
-
Keller, H.1
Kneissel, M.2
-
28
-
-
26444484606
-
Effects of parathyroid hormone on Wnt signaling pathway in bone
-
Kulkarni NH, Halladay DL, Miles RR, Gilbert LM, Frolik CA, et al. (2005) Effects of parathyroid hormone on Wnt signaling pathway in bone. J Cell Biochem 95: 1178-1190.
-
(2005)
J Cell Biochem
, vol.95
, pp. 1178-1190
-
-
Kulkarni, N.H.1
Halladay, D.L.2
Miles, R.R.3
Gilbert, L.M.4
Frolik, C.A.5
-
29
-
-
0038165507
-
Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics
-
Qin L, Qiu P, Wang L, Li X, Swarthout JT, et al. (2003) Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics. J Biol Chem 278: 19723-19731.
-
(2003)
J Biol Chem
, vol.278
, pp. 19723-19731
-
-
Qin, L.1
Qiu, P.2
Wang, L.3
Li, X.4
Swarthout, J.T.5
-
30
-
-
46449131544
-
PTH/ cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3beta in osteoblastic Saos-2 cells
-
Suzuki A, Ozono K, Kubota T, Kondou H, Tachikawa K, et al. (2008) PTH/ cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3beta in osteoblastic Saos-2 cells. J Cell Biochem 104: 304-317.
-
(2008)
J Cell Biochem
, vol.104
, pp. 304-317
-
-
Suzuki, A.1
Ozono, K.2
Kubota, T.3
Kondou, H.4
Tachikawa, K.5
-
31
-
-
69149106680
-
T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling
-
Terauchi M, Li JY, Bedi B, Baek KH, Tawfeek H, et al. (2009) T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell Metab 10: 229-240.
-
(2009)
Cell Metab
, vol.10
, pp. 229-240
-
-
Terauchi, M.1
Li, J.Y.2
Bedi, B.3
Baek, K.H.4
Tawfeek, H.5
-
32
-
-
55749091843
-
Parathyroid hormone signaling through low-density lipoprotein-related protein 6
-
Wan M, Yang C, Li J, Wu X, Yuan H, et al. (2008) Parathyroid hormone signaling through low-density lipoprotein-related protein 6. Genes Dev 22: 2968-2979.
-
(2008)
Genes Dev
, vol.22
, pp. 2968-2979
-
-
Wan, M.1
Yang, C.2
Li, J.3
Wu, X.4
Yuan, H.5
-
33
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
-
Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, et al. (2003) The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 349: 2483-2494.
-
(2003)
N Engl J Med
, vol.349
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
Rasmussen, E.4
Ma, Y.5
-
34
-
-
8844264524
-
The SCID-rab model: A novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells
-
Yata K, Yaccoby S (2004) The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells. Leukemia 18: 1891-1897.
-
(2004)
Leukemia
, vol.18
, pp. 1891-1897
-
-
Yata, K.1
Yaccoby, S.2
-
35
-
-
0032532608
-
Primary myeloma cells growing in SCID-hu mice: A model for studying the biology and treatment of myeloma and its manifestations
-
Yaccoby S, Barlogie B, Epstein J (1998) Primary myeloma cells growing in SCID-hu mice: a model for studying the biology and treatment of myeloma and its manifestations. Blood 92: 2908-2913.
-
(1998)
Blood
, vol.92
, pp. 2908-2913
-
-
Yaccoby, S.1
Barlogie, B.2
Epstein, J.3
-
36
-
-
0033570946
-
The proliferative potential of myeloma plasma cells manifest in the SCID-hu host
-
Yaccoby S, Epstein J (1999) The proliferative potential of myeloma plasma cells manifest in the SCID-hu host. Blood 94: 3576-3582.
-
(1999)
Blood
, vol.94
, pp. 3576-3582
-
-
Yaccoby, S.1
Epstein, J.2
-
37
-
-
0036181668
-
Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity
-
Yaccoby S, Pearse RN, Johnson CL, Barlogie B, Choi Y, et al. (2002) Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity. Br J Haematol 116: 278-290.
-
(2002)
Br J Haematol
, vol.116
, pp. 278-290
-
-
Yaccoby, S.1
Pearse, R.N.2
Johnson, C.L.3
Barlogie, B.4
Choi, Y.5
-
38
-
-
34548168002
-
Establishment and exploitation of hyperdiploid and non-hyperdiploid human myeloma cell lines
-
Li X, Pennisi A, Zhan F, Sawyer JR, Shaughnessy JD, et al. (2007) Establishment and exploitation of hyperdiploid and non-hyperdiploid human myeloma cell lines. Br J Haematol 138: 802-811.
-
(2007)
Br J Haematol
, vol.138
, pp. 802-811
-
-
Li, X.1
Pennisi, A.2
Zhan, F.3
Sawyer, J.R.4
Shaughnessy, J.D.5
-
39
-
-
33745779502
-
The molecular classification of multiple myeloma
-
Zhan F, Huang Y, Colla S, Stewart JP, Hanamura I, et al. (2006) The molecular classification of multiple myeloma. Blood 108: 2020-2028.
-
(2006)
Blood
, vol.108
, pp. 2020-2028
-
-
Zhan, F.1
Huang, Y.2
Colla, S.3
Stewart, J.P.4
Hanamura, I.5
-
40
-
-
0034980787
-
Expression and in vitro modification of parathyroid hormone-related protein (PTHrP) and PTH/PTHrP-receptor in human myeloma cells
-
Otsuki T, Yamada O, Kurebayashi J, Sakaguchi H, Yata K, et al. (2001) Expression and in vitro modification of parathyroid hormone-related protein (PTHrP) and PTH/PTHrP-receptor in human myeloma cells. Leuk Lymphoma 41: 397-409.
-
(2001)
Leuk Lymphoma
, vol.41
, pp. 397-409
-
-
Otsuki, T.1
Yamada, O.2
Kurebayashi, J.3
Sakaguchi, H.4
Yata, K.5
-
41
-
-
33845978384
-
Parathyroid hormone activates phosphoinositide 3-kinase-Akt-Bad cascade in osteoblast-like cells
-
Yamamoto T, Kambe F, Cao X, Lu X, Ishiguro N, et al. (2007) Parathyroid hormone activates phosphoinositide 3-kinase-Akt-Bad cascade in osteoblast-like cells. Bone 40: 354-359.
-
(2007)
Bone
, vol.40
, pp. 354-359
-
-
Yamamoto, T.1
Kambe, F.2
Cao, X.3
Lu, X.4
Ishiguro, N.5
-
42
-
-
21344454577
-
Parathyroid hormone and teriparatide for the treatment of osteoporosis: A review of the evidence and suggested guidelines for its use
-
Hodsman AB, Bauer DC, Dempster DW, Dian L, Hanley DA, et al. (2005) Parathyroid hormone and teriparatide for the treatment of osteoporosis: a review of the evidence and suggested guidelines for its use. Endocr Rev 26: 688-703.
-
(2005)
Endocr Rev
, vol.26
, pp. 688-703
-
-
Hodsman, A.B.1
Bauer, D.C.2
Dempster, D.W.3
Dian, L.4
Hanley, D.A.5
-
43
-
-
10744231292
-
Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism
-
Bellido T, Ali AA, Plotkin LI, Fu Q, Gubrij I, et al. (2003) Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism. J Biol Chem 278: 50259-50272.
-
(2003)
J Biol Chem
, vol.278
, pp. 50259-50272
-
-
Bellido, T.1
Ali, A.A.2
Plotkin, L.I.3
Fu, Q.4
Gubrij, I.5
-
44
-
-
29644433621
-
Parathyroid hormone: Past and present
-
Potts JT (2005) Parathyroid hormone: past and present. J Endocrinol 187: 311-325.
-
(2005)
J Endocrinol
, vol.187
, pp. 311-325
-
-
Potts, J.T.1
-
45
-
-
71549119792
-
PDE4 inhibitor upregulates PTH-induced osteoclast formation via CRE-mediated COX-2 expression in osteoblasts
-
Park H, No AL, Lee JM, Chen L, Lee SY, et al. (2010) PDE4 inhibitor upregulates PTH-induced osteoclast formation via CRE-mediated COX-2 expression in osteoblasts. FEBS Lett 584: 173-180.
-
(2010)
FEBS Lett
, vol.584
, pp. 173-180
-
-
Park, H.1
No, A.L.2
Lee, J.M.3
Chen, L.4
Lee, S.Y.5
-
46
-
-
0037045407
-
Parathyroid hormone-dependent signaling pathways regulating genes in bone cells
-
Swarthout JT, D'Alonzo RC, Selvamurugan N, Partridge NC (2002) Parathyroid hormone-dependent signaling pathways regulating genes in bone cells. Gene 282: 1-17.
-
(2002)
Gene
, vol.282
, pp. 1-17
-
-
Swarthout, J.T.1
D'alonzo, R.C.2
Selvamurugan, N.3
Partridge, N.C.4
-
47
-
-
23844535637
-
Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: An analysis by DNA microarray
-
Onyia JE, Helvering LM, Gelbert L, Wei T, Huang S, et al. (2005) Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: an analysis by DNA microarray. J Cell Biochem 95: 403-418.
-
(2005)
J Cell Biochem
, vol.95
, pp. 403-418
-
-
Onyia, J.E.1
Helvering, L.M.2
Gelbert, L.3
Wei, T.4
Huang, S.5
-
48
-
-
77953006287
-
Building bone with a SOST-PTH partnership
-
Sims NA (2010) Building bone with a SOST-PTH partnership. J Bone Miner Res 25: 175-177.
-
(2010)
J Bone Miner Res
, vol.25
, pp. 175-177
-
-
Sims, N.A.1
-
49
-
-
79960021731
-
Targeted overexpression of Dkk1 in osteoblasts reduces bone mass but does not impair the anabolic response to intermittent PTH treatment in mice
-
Yao GQ, Wu JJ, Troiano N, Insogna K (2010) Targeted overexpression of Dkk1 in osteoblasts reduces bone mass but does not impair the anabolic response to intermittent PTH treatment in mice. J Bone Miner Metab.
-
(2010)
J Bone Miner Metab
-
-
Yao, G.Q.1
Wu, J.J.2
Troiano, N.3
Insogna, K.4
-
50
-
-
70949101564
-
Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo
-
Choi HY, Dieckmann M, Herz J, Niemeier A (2009) Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo. PLoS ONE 4: e7930.
-
(2009)
PLoS ONE
, vol.4
-
-
Choi, H.Y.1
Dieckmann, M.2
Herz, J.3
Niemeier, A.4
-
51
-
-
54249096215
-
Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase
-
Liu Y, Rubin B, Bodine PV, Billiard J (2008) Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase. J Cell Biochem 105: 497-502.
-
(2008)
J Cell Biochem
, vol.105
, pp. 497-502
-
-
Liu, Y.1
Rubin, B.2
Bodine, P.V.3
Billiard, J.4
-
52
-
-
34848814178
-
Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription
-
Almeida M, Han L, Martin-Millan M, O'Brien CA, Manolagas SC (2007) Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription. J Biol Chem 282: 27298-27305.
-
(2007)
J Biol Chem
, vol.282
, pp. 27298-27305
-
-
Almeida, M.1
Han, L.2
Martin-Millan, M.3
O'Brien, C.A.4
Manolagas, S.C.5
-
53
-
-
75149146587
-
FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice
-
Ambrogini E, Almeida M, Martin-Millan M, Paik JH, DePinho RA, et al. (2010) FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice. Cell Metab 11: 136-146.
-
(2010)
Cell Metab
, vol.11
, pp. 136-146
-
-
Ambrogini, E.1
Almeida, M.2
Martin-Millan, M.3
Paik, J.H.4
Depinho, R.A.5
-
54
-
-
75149115329
-
FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts
-
Rached MT, Kode A, Xu L, Yoshikawa Y, Paik JH, DePinho RA, et al. (2010) FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts. Cell Metab 11: 147-160.
-
(2010)
Cell Metab
, vol.11
, pp. 147-160
-
-
Rached, M.T.1
Kode, A.2
Xu, L.3
Yoshikawa, Y.4
Paik, J.H.5
Depinho, R.A.6
-
55
-
-
47849098824
-
EphrinB2 Regulation by Parathyroid Hormone (PTH) and PTHrP Revealed by Molecular Profiling in Differentiating Osteoblasts
-
Allan EH, Hausler KD, Wei T, Gooi JH, Quinn JM, et al. (2008) EphrinB2 Regulation by Parathyroid Hormone (PTH) and PTHrP Revealed by Molecular Profiling in Differentiating Osteoblasts. J Bone Miner Res.
-
(2008)
J Bone Miner Res
-
-
Allan, E.H.1
Hausler, K.D.2
Wei, T.3
Gooi, J.H.4
Quinn, J.M.5
-
56
-
-
70349263942
-
The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth
-
Pennisi A, Ling W, Li X, Khan S, Shaughnessy JD, Jr., et al. (2009) The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth. Blood 114: 1803-1812.
-
(2009)
Blood
, vol.114
, pp. 1803-1812
-
-
Pennisi, A.1
Ling, W.2
Li, X.3
Khan, S.4
Shaughnessy Jr., J.D.5
-
57
-
-
74249106462
-
COMP-Ang1, a chimeric form of Angiopoietin 1, enhances BMP2-induced osteoblast differentiation and bone formation
-
Jeong BC, Kim HJ, Bae IH, Lee KN, Lee KY, et al. (2010) COMP-Ang1, a chimeric form of Angiopoietin 1, enhances BMP2-induced osteoblast differentiation and bone formation. Bone 46: 479-486.
-
(2010)
Bone
, vol.46
, pp. 479-486
-
-
Jeong, B.C.1
Kim, H.J.2
Bae, I.H.3
Lee, K.N.4
Lee, K.Y.5
-
58
-
-
60849137479
-
Endogenous FGF-2 is critically important in PTH anabolic effects on bone
-
Sabbieti MG, Agas D, Xiao L, Marchetti L, Coffin JD, et al. (2009) Endogenous FGF-2 is critically important in PTH anabolic effects on bone. J Cell Physiol 219: 143-151.
-
(2009)
J Cell Physiol
, vol.219
, pp. 143-151
-
-
Sabbieti, M.G.1
Agas, D.2
Xiao, L.3
Marchetti, L.4
Coffin, J.D.5
-
59
-
-
0033577851
-
Parathyroid hormone-related peptide (PTHrP)-dependent and -independent effects of transforming growth factor beta (TGF-beta) on endochondral bone formation
-
Serra R, Karaplis A, Sohn P (1999) Parathyroid hormone-related peptide (PTHrP)-dependent and -independent effects of transforming growth factor beta (TGF-beta) on endochondral bone formation. J Cell Biol 145: 783-794.
-
(1999)
J Cell Biol
, vol.145
, pp. 783-794
-
-
Serra, R.1
Karaplis, A.2
Sohn, P.3
-
60
-
-
67650506105
-
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
-
Tang Y, Wu X, Lei W, Pang L, Wan C, et al. (2009) TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med 15: 757-765.
-
(2009)
Nat Med
, vol.15
, pp. 757-765
-
-
Tang, Y.1
Wu, X.2
Lei, W.3
Pang, L.4
Wan, C.5
-
61
-
-
73849120770
-
Investigating the role of PDGF as a potential drug therapy in bone formation and fracture healing
-
Graham S, Leonidou A, Lester M, Heliotis M, Mantalaris A, et al. (2009) Investigating the role of PDGF as a potential drug therapy in bone formation and fracture healing. Expert Opin Investig Drugs 18: 1633-1654.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 1633-1654
-
-
Graham, S.1
Leonidou, A.2
Lester, M.3
Heliotis, M.4
Mantalaris, A.5
-
62
-
-
33144457259
-
A novel tetracycline labeling schedule for longitudinal evaluation of the short-term effects of anabolic therapy with a single iliac crest bone biopsy: Early actions of teriparatide
-
Lindsay R, Cosman F, Zhou H, Bostrom MP, Shen VW, et al. (2006) A novel tetracycline labeling schedule for longitudinal evaluation of the short-term effects of anabolic therapy with a single iliac crest bone biopsy: early actions of teriparatide. J Bone Miner Res 21: 366-373.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 366-373
-
-
Lindsay, R.1
Cosman, F.2
Zhou, H.3
Bostrom, M.P.4
Shen, V.W.5
-
63
-
-
61849109895
-
Targeting bone remodeling for the treatment of osteoporosis: Summary of the proceedings of an ASBMR workshop
-
Bilezikian JP, Matsumoto T, Bellido T, Khosla S, Martin J, et al. (2009) Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop. J Bone Miner Res 24: 373-385.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 373-385
-
-
Bilezikian, J.P.1
Matsumoto, T.2
Bellido, T.3
Khosla, S.4
Martin, J.5
-
64
-
-
47249093295
-
Role of decorin in the antimyeloma effects of osteoblasts
-
Li X, Pennisi A, Yaccoby S (2008) Role of decorin in the antimyeloma effects of osteoblasts. Blood 112: 159-168.
-
(2008)
Blood
, vol.112
, pp. 159-168
-
-
Li, X.1
Pennisi, A.2
Yaccoby, S.3
-
65
-
-
67649171661
-
Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6
-
Lee RH, Pulin AA, Seo MJ, Kota DJ, Ylostalo J, et al. (2009) Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 5: 54-63.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 54-63
-
-
Lee, R.H.1
Pulin, A.A.2
Seo, M.J.3
Kota, D.J.4
Ylostalo, J.5
-
66
-
-
70350761864
-
BRAK/CXCL14 expression in oral carcinoma cells completely suppresses tumor cell xenografts in SCID mouse
-
Ozawa S, Kato Y, Kubota E, Hata R (2009) BRAK/CXCL14 expression in oral carcinoma cells completely suppresses tumor cell xenografts in SCID mouse. Biomed Res 30: 315-318.
-
(2009)
Biomed Res
, vol.30
, pp. 315-318
-
-
Ozawa, S.1
Kato, Y.2
Kubota, E.3
Hata, R.4
-
67
-
-
43649100746
-
Daintain/AIF-1 promotes breast cancer proliferation via activation of the NF-kappaB/cyclin D1 pathway and facilitates tumor growth
-
Liu S, Tan WY, Chen QR, Chen XP, Fu K, et al. (2008) Daintain/AIF-1 promotes breast cancer proliferation via activation of the NF-kappaB/cyclin D1 pathway and facilitates tumor growth. Cancer Sci 99: 952-957.
-
(2008)
Cancer Sci
, vol.99
, pp. 952-957
-
-
Liu, S.1
Tan, W.Y.2
Chen, Q.R.3
Chen, X.P.4
Fu, K.5
-
68
-
-
0032528180
-
Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone
-
Weinstein RS, Jilka RL, Parfitt AM, Manolagas SC (1998) Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J Clin Invest 102: 274-282.
-
(1998)
J Clin Invest
, vol.102
, pp. 274-282
-
-
Weinstein, R.S.1
Jilka, R.L.2
Parfitt, A.M.3
Manolagas, S.C.4
-
69
-
-
77954505723
-
Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice
-
Weinstein RS, Jilka RL, Almeida M, Roberson PK, Manolagas SC (2010) Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice. Endocrinology 151: 2641-2649.
-
(2010)
Endocrinology
, vol.151
, pp. 2641-2649
-
-
Weinstein, R.S.1
Jilka, R.L.2
Almeida, M.3
Roberson, P.K.4
Manolagas, S.C.5
-
70
-
-
58149478516
-
The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo
-
Pennisi A, Li X, Ling W, Khan S, Zangari M, et al. (2009) The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo. Am J Hematol 84: 6-14.
-
(2009)
Am J Hematol
, vol.84
, pp. 6-14
-
-
Pennisi, A.1
Li, X.2
Ling, W.3
Khan, S.4
Zangari, M.5
-
71
-
-
27744557499
-
Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma
-
Zangari M, Esseltine D, Lee CK, Barlogie B, Elice F, et al. (2005) Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma. Br J Haematol 131: 71-73.
-
(2005)
Br J Haematol
, vol.131
, pp. 71-73
-
-
Zangari, M.1
Esseltine, D.2
Lee, C.K.3
Barlogie, B.4
Elice, F.5
-
72
-
-
33947370286
-
Inhibin A is an endocrine stimulator of bone mass and strength
-
Perrien DS, Akel NS, Edwards PK, Carver AA, Bendre MS, et al. (2007) Inhibin A is an endocrine stimulator of bone mass and strength. Endocrinology 148: 1654-1665.
-
(2007)
Endocrinology
, vol.148
, pp. 1654-1665
-
-
Perrien, D.S.1
Akel, N.S.2
Edwards, P.K.3
Carver, A.A.4
Bendre, M.S.5
-
73
-
-
0036792257
-
Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo
-
Bendre MS, Gaddy-Kurten D, Mon-Foote T, Akel NS, Skinner RA, et al. (2002) Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo. Cancer Res 62: 5571-5579.
-
(2002)
Cancer Res
, vol.62
, pp. 5571-5579
-
-
Bendre, M.S.1
Gaddy-Kurten, D.2
Mon-Foote, T.3
Akel, N.S.4
Skinner, R.A.5
-
74
-
-
0034103380
-
Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: Antagonism by noggin
-
Abe E, Yamamoto M, Taguchi Y, Lecka-Czernik B, O'Brien CA, et al. (2000) Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin. J Bone Miner Res 15: 663-673.
-
(2000)
J Bone Miner Res
, vol.15
, pp. 663-673
-
-
Abe, E.1
Yamamoto, M.2
Taguchi, Y.3
Lecka-Czernik, B.4
O'Brien, C.A.5
|