-
1
-
-
26044478519
-
The relationship between bone mineral density and fracture risk
-
McClung MR (2005) The relationship between bone mineral density and fracture risk. Curr Osteoporos Rep 3: 57-63.
-
(2005)
Curr Osteoporos Rep
, vol.3
, pp. 57-63
-
-
McClung, M.R.1
-
2
-
-
34347372696
-
The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women
-
Kanis JA, Oden A, Johnell O, Johansson H, De Laet C, et al. (2007) The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. Osteoporos Int 18: 1033-1046.
-
(2007)
Osteoporos Int
, vol.18
, pp. 1033-1046
-
-
Kanis, J.A.1
Oden, A.2
Johnell, O.3
Johansson, H.4
De Laet, C.5
-
3
-
-
58049204438
-
Potential new drug targets for osteoporosis
-
Deal C (2009) Potential new drug targets for osteoporosis. Nat Clin Pract Rheumatol 5: 20-27.
-
(2009)
Nat Clin Pract Rheumatol
, vol.5
, pp. 20-27
-
-
Deal, C.1
-
5
-
-
34250823973
-
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton
-
Baron R, Rawadi G (2007) Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton. Endocrinology 148: 2635-2643.
-
(2007)
Endocrinology
, vol.148
, pp. 2635-2643
-
-
Baron, R.1
Rawadi, G.2
-
7
-
-
58149145443
-
New sequence variants associated with bone mineral density
-
Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, Gudbjartsson DF, Walters GB, et al. (2009) New sequence variants associated with bone mineral density. Nat Genet 41: 15-17.
-
(2009)
Nat Genet
, vol.41
, pp. 15-17
-
-
Styrkarsdottir, U.1
Halldorsson, B.V.2
Gretarsdottir, S.3
Gudbjartsson, D.F.4
Walters, G.B.5
-
8
-
-
44349167229
-
Multiple genetic loci for bone mineral density and fractures
-
Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, Gudbjartsson DF, Walters GB, et al. (2008) Multiple genetic loci for bone mineral density and fractures. N Engl J Med 358: 2355-2365.
-
(2008)
N Engl J Med
, vol.358
, pp. 2355-2365
-
-
Styrkarsdottir, U.1
Halldorsson, B.V.2
Gretarsdottir, S.3
Gudbjartsson, D.F.4
Walters, G.B.5
-
9
-
-
0038267120
-
Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity
-
Kusu N, Laurikkala J, Imanishi M, Usui H, Konishi M, et al. (2003) Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity. J Biol Chem 278: 24113-24117.
-
(2003)
J Biol Chem
, vol.278
, pp. 24113-24117
-
-
Kusu, N.1
Laurikkala, J.2
Imanishi, M.3
Usui, H.4
Konishi, M.5
-
10
-
-
10744221383
-
Osteocyte control of bone formation via sclerostin, a novel BMP antagonist
-
Winkler DG, Sutherland MK, Geoghegan JC, Yu C, Hayes T, et al. (2003) Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. EMBO J 22: 6267-6276.
-
(2003)
EMBO J
, vol.22
, pp. 6267-6276
-
-
Winkler, D.G.1
Sutherland, M.K.2
Geoghegan, J.C.3
Yu, C.4
Hayes, T.5
-
11
-
-
13244298422
-
Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins
-
Winkler DG, Sutherland MS, Ojala E, Turcott E, Geoghegan JC, et al. (2005) Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins. J Biol Chem 280: 2498-2502.
-
(2005)
J Biol Chem
, vol.280
, pp. 2498-2502
-
-
Winkler, D.G.1
Sutherland, M.S.2
Ojala, E.3
Turcott, E.4
Geoghegan, J.C.5
-
12
-
-
21244480924
-
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
-
Li X, Zhang Y, Kang H, Liu W, Liu P, et al. (2005) Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem 280: 19883-19887.
-
(2005)
J Biol Chem
, vol.280
, pp. 19883-19887
-
-
Li, X.1
Zhang, Y.2
Kang, H.3
Liu, W.4
Liu, P.5
-
13
-
-
58149330442
-
Lrp4 modulates extracellular integration of cell signaling pathways in development
-
Ohazama A, Johnson EB, Ota MS, Choi HY, Porntaveetus T, et al. (2008) Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One 3: e4092.
-
(2008)
PLoS One
, vol.3
-
-
Ohazama, A.1
Johnson, E.B.2
Ota, M.S.3
Choi, H.Y.4
Porntaveetus, T.5
-
14
-
-
0000063546
-
Lipoprotein receptors: New roles for ancient proteins
-
Willnow TE, Nykjaer A, Herz J (1999) Lipoprotein receptors: new roles for ancient proteins. Nat Cell Biol 1: E157-E162.
-
(1999)
Nat Cell Biol
, vol.1
-
-
Willnow, T.E.1
Nykjaer, A.2
Herz, J.3
-
16
-
-
66349124185
-
Expanding functions of lipoprotein receptors
-
Herz J, Chen Y, Masiulis I, Zhou L (2009) Expanding functions of lipoprotein receptors. J Lipid Res 50 Suppl. pp S287-S292.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Herz, J.1
Chen, Y.2
Masiulis, I.3
Zhou, L.4
-
17
-
-
14444283111
-
A novel low-density lipoprotein receptor-related protein with type II membrane protein-like structure is abundant in heart
-
Tomita Y, Kim DH, Magoori K, Fujino T, Yamamoto TT (1998) A novel low-density lipoprotein receptor-related protein with type II membrane protein-like structure is abundant in heart. J Biochem 124: 784-789.
-
(1998)
J Biochem
, vol.124
, pp. 784-789
-
-
Tomita, Y.1
Kim, D.H.2
Magoori, K.3
Fujino, T.4
Yamamoto, T.T.5
-
18
-
-
27944471018
-
Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice
-
Johnson EB, Hammer RE, Herz J (2005) Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Hum Mol Genet 14: 3523-3538.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3523-3538
-
-
Johnson, E.B.1
Hammer, R.E.2
Herz, J.3
-
19
-
-
33646770321
-
Expression of low density lipoprotein receptor-related protein 4 (Lrp4) gene in the mouse germ cells
-
Yamaguchi YL, Tanaka SS, Kasa M, Yasuda K, Tam PP, et al. (2006) Expression of low density lipoprotein receptor-related protein 4 (Lrp4) gene in the mouse germ cells. Gene Expr Patterns 6: 607-612.
-
(2006)
Gene Expr Patterns
, vol.6
, pp. 607-612
-
-
Yamaguchi, Y.L.1
Tanaka, S.S.2
Kasa, M.3
Yasuda, K.4
Tam, P.P.5
-
20
-
-
33846155569
-
LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction
-
Weatherbee SD, Anderson KV, Niswander LA (2006) LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction. Development 133: 4993-5000.
-
(2006)
Development
, vol.133
, pp. 4993-5000
-
-
Weatherbee, S.D.1
Anderson, K.V.2
Niswander, L.A.3
-
21
-
-
53849093434
-
LRP4 serves as a coreceptor of agrin
-
Zhang B, Luo S, Wang Q, Suzuki T, Xiong WC, et al. (2008) LRP4 serves as a coreceptor of agrin. Neuron 60: 285-297.
-
(2008)
Neuron
, vol.60
, pp. 285-297
-
-
Zhang, B.1
Luo, S.2
Wang, Q.3
Suzuki, T.4
Xiong, W.C.5
-
22
-
-
55049092996
-
Lrp4 is a receptor for Agrin and forms a complex with MuSK
-
Kim N, Stiegler AL, Cameron TO, Hallock PT, Gomez AM, et al. (2008) Lrp4 is a receptor for Agrin and forms a complex with MuSK. Cell 135: 334-342.
-
(2008)
Cell
, vol.135
, pp. 334-342
-
-
Kim, N.1
Stiegler, A.L.2
Cameron, T.O.3
Hallock, P.T.4
Gomez, A.M.5
-
23
-
-
33646110494
-
Mutations in the gene encoding the low-density lipoprotein receptor LRP4 cause abnormal limb development in the mouse
-
Simon-Chazottes D, Tutois S, Kuehn M, Evans M, Bourgade F, et al. (2006) Mutations in the gene encoding the low-density lipoprotein receptor LRP4 cause abnormal limb development in the mouse. Genomics 87: 673-677.
-
(2006)
Genomics
, vol.87
, pp. 673-677
-
-
Simon-Chazottes, D.1
Tutois, S.2
Kuehn, M.3
Evans, M.4
Bourgade, F.5
-
24
-
-
33847767522
-
Congenital syndactyly in cattle: Four novel mutations in the low density lipoprotein receptor-related protein 4 gene (LRP4)
-
Drogemuller C, Leeb T, Harlizius B, Tammen I, Distl O, et al. (2007) Congenital syndactyly in cattle: four novel mutations in the low density lipoprotein receptor-related protein 4 gene (LRP4). BMC Genet 8: 5.
-
(2007)
BMC Genet
, vol.8
, pp. 5
-
-
Drogemuller, C.1
Leeb, T.2
Harlizius, B.3
Tammen, I.4
Distl, O.5
-
25
-
-
34250840514
-
The genetics of low-density lipoprotein receptor-related protein 5 in bone: A story of extremes
-
Balemans W, Van Hul W (2007) The genetics of low-density lipoprotein receptor-related protein 5 in bone: a story of extremes. Endocrinology 148: 2622-2629.
-
(2007)
Endocrinology
, vol.148
, pp. 2622-2629
-
-
Balemans, W.1
Van Hul, W.2
-
26
-
-
58649087137
-
Where Wnts went: The exploding field of Lrp5 and Lrp6 signaling in bone
-
Williams BO, Insogna KL (2009) Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone. J Bone Miner Res 24: 171-178.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 171-178
-
-
Williams, B.O.1
Insogna, K.L.2
-
27
-
-
33846449190
-
Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity
-
Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, et al. (2006) Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res 21: 1738-1749.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 1738-1749
-
-
Ellies, D.L.1
Viviano, B.2
McCarthy, J.3
Rey, J.P.4
Itasaki, N.5
-
28
-
-
0035282968
-
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
-
Balemans W, Ebeling M, Patel N, Van Hul E, Olson P, et al. (2001) Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST). Hum Mol Genet 10: 537-543.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 537-543
-
-
Balemans, W.1
Ebeling, M.2
Patel, N.3
Van Hul, E.4
Olson, P.5
-
29
-
-
0035089781
-
Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein
-
Brunkow ME, Gardner JC, Van Ness J, Paeper BW, Kovacevich BR, et al. (2001) Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. Am J Hum Genet 68: 577-589.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 577-589
-
-
Brunkow, M.E.1
Gardner, J.C.2
Van Ness, J.3
Paeper, B.W.4
Kovacevich, B.R.5
-
30
-
-
0008294029
-
Localization of the gene for sclerosteosis to the van Buchem disease-gene region on chromosome 17q12-q21
-
Balemans W, Van Den EJ, Freire Paes-Alves A, Dikkers FG, Willems PJ, et al. (1999) Localization of the gene for sclerosteosis to the van Buchem disease-gene region on chromosome 17q12-q21. Am J Hum Genet 64: 1661-1669.
-
(1999)
Am J Hum Genet
, vol.64
, pp. 1661-1669
-
-
Balemans, W.V.D.E.1
Freire Paes-Alves, A.2
Dikkers, F.G.3
Willems, P.J.4
-
31
-
-
18244403197
-
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
-
Balemans W, Patel N, Ebeling M, Van Hul E, Wuyts W, et al. (2002) Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease. J Med Genet 39: 91-97.
-
(2002)
J Med Genet
, vol.39
, pp. 91-97
-
-
Balemans, W.1
Patel, N.2
Ebeling, M.3
Van Hul, E.4
Wuyts, W.5
-
32
-
-
22244474640
-
Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
-
Loots GG, Kneissel M, Keller H, Baptist M, Chang J, et al. (2005) Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease. Genome Res 15: 928-935.
-
(2005)
Genome Res
, vol.15
, pp. 928-935
-
-
Loots, G.G.1
Kneissel, M.2
Keller, H.3
Baptist, M.4
Chang, J.5
-
33
-
-
44449099165
-
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
-
Li X, Ominsky MS, Niu QT, Sun N, Daugherty B, et al. (2008) Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res 23: 860-869.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 860-869
-
-
Li, X.1
Ominsky, M.S.2
Niu, Q.T.3
Sun, N.4
Daugherty, B.5
-
34
-
-
0035902050
-
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
-
Mao B, Wu W, Li Y, Hoppe D, Stannek P, et al. (2001) LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411: 321-325.
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.1
Wu, W.2
Li, Y.3
Hoppe, D.4
Stannek, P.5
-
35
-
-
0034933057
-
Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/ Arrow
-
Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA (2001) Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/ Arrow. Nat Cell Biol 3: 683-686.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 683-686
-
-
Bafico, A.1
Liu, G.2
Yaniv, A.3
Gazit, A.4
Aaronson, S.A.5
-
36
-
-
33847671336
-
Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling
-
Bhat BM, Allen KM, Liu W, Graham J, Morales A, et al. (2007) Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling. Gene 391: 103-112.
-
(2007)
Gene
, vol.391
, pp. 103-112
-
-
Bhat, B.M.1
Allen, K.M.2
Liu, W.3
Graham, J.4
Morales, A.5
-
37
-
-
34447526757
-
Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of Wnt signaling
-
Balemans W, Devogelaer JP, Cleiren E, Piters E, Caussin E, et al. (2007) Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of Wnt signaling. J Bone Miner Res 22: 708-716.
-
(2007)
J Bone Miner Res
, vol.22
, pp. 708-716
-
-
Balemans, W.1
Devogelaer, J.P.2
Cleiren, E.3
Piters, E.4
Caussin, E.5
-
38
-
-
0037030681
-
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling
-
Mao B, Wu W, Davidson G, Marhold J, Li M, et al. (2002) Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. Nature 417: 664-667.
-
(2002)
Nature
, vol.417
, pp. 664-667
-
-
Mao, B.1
Wu, W.2
Davidson, G.3
Marhold, J.4
Li, M.5
-
39
-
-
53149087478
-
Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism
-
Wang K, Zhang Y, Li X, Chen L, Wang H, et al. (2008) Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism. J Biol Chem 283: 23371-23375.
-
(2008)
J Biol Chem
, vol.283
, pp. 23371-23375
-
-
Wang, K.1
Zhang, Y.2
Li, X.3
Chen, L.4
Wang, H.5
-
40
-
-
18044399916
-
Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse
-
Mukhopadhyay M, Shtrom S, Rodriguez-Esteban C, Chen L, Tsukui T, et al. (2001) Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Dev Cell 1: 423-434.
-
(2001)
Dev Cell
, vol.1
, pp. 423-434
-
-
Mukhopadhyay, M.1
Shtrom, S.2
Rodriguez-Esteban, C.3
Chen, L.4
Tsukui, T.5
-
41
-
-
2342436339
-
Hypomorphic expression of Dkk1 in the doubleridge mouse: Dose dependence and compensatory interactions with Lrp6
-
MacDonald BT, Adamska M, Meisler MH (2004) Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development 131: 2543-2552.
-
(2004)
Development
, vol.131
, pp. 2543-2552
-
-
MacDonald, B.T.1
Adamska, M.2
Meisler, M.H.3
-
42
-
-
34547561383
-
Bone mass is inversely proportional to Dkk1 levels in mice
-
MacDonald BT, Joiner DM, Oyserman SM, Sharma P, Goldstein SA, et al. (2007) Bone mass is inversely proportional to Dkk1 levels in mice. Bone 41: 331-339.
-
(2007)
Bone
, vol.41
, pp. 331-339
-
-
MacDonald, B.T.1
Joiner, D.M.2
Oyserman, S.M.3
Sharma, P.4
Goldstein, S.A.5
-
43
-
-
20344398197
-
Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling
-
Ai M, Holmen SL, Van Hul W, Williams BO, Warman ML (2005) Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling. Mol Cell Biol 25: 4946-4955.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4946-4955
-
-
Ai, M.1
Holmen, S.L.2
Van Hul, W.3
Williams, B.O.4
Warman, M.L.5
-
44
-
-
0037118285
-
High bone density due to a mutation in LDL-receptor-related protein 5
-
Boyden LM, Mao J, Belsky J, Mitzner L, Farhi A, et al. (2002) High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med 346: 1513-1521.
-
(2002)
N Engl J Med
, vol.346
, pp. 1513-1521
-
-
Boyden, L.M.1
Mao, J.2
Belsky, J.3
Mitzner, L.4
Farhi, A.5
-
45
-
-
55249101949
-
The binding between sclerostin and LRP5 is altered by DKK1 and by high-bone mass LRP5 mutations
-
Balemans W, Piters E, Cleiren E, Ai M, Van Wesenbeeck L, et al. (2008) The binding between sclerostin and LRP5 is altered by DKK1 and by high-bone mass LRP5 mutations. Calcif Tissue Int 82: 445-453.
-
(2008)
Calcif Tissue Int
, vol.82
, pp. 445-453
-
-
Balemans, W.1
Piters, E.2
Cleiren, E.3
Ai, M.4
Van Wesenbeeck, L.5
-
46
-
-
0036500653
-
The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death
-
Grotewold L, Ruther U (2002) The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J 21: 966-975.
-
(2002)
EMBO J
, vol.21
, pp. 966-975
-
-
Grotewold, L.1
Ruther, U.2
-
47
-
-
8844261126
-
Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites
-
Uitterlinden AG, Arp PP, Paeper BW, Charmley P, Proll S, et al. (2004) Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites. Am J Hum Genet 75: 1032-1045.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 1032-1045
-
-
Uitterlinden, A.G.1
Arp, P.P.2
Paeper, B.W.3
Charmley, P.4
Proll, S.5
-
48
-
-
41849149688
-
Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes
-
Sims AM, Shephard N, Carter K, Doan T, Dowling A, et al. (2008) Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes. J Bone Miner Res 23: 499-506.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 499-506
-
-
Sims, A.M.1
Shephard, N.2
Carter, K.3
Doan, T.4
Dowling, A.5
-
49
-
-
59149096379
-
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
-
Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, et al. (2008) BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development 135: 3801-3811.
-
(2008)
Development
, vol.135
, pp. 3801-3811
-
-
Kamiya, N.1
Ye, L.2
Kobayashi, T.3
Mochida, Y.4
Yamauchi, M.5
-
50
-
-
33845927993
-
Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
-
van Bezooijen RL, Svensson JP, Eefting D, Visser A, van der HG, et al. (2007) Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation. J Bone Miner Res 22: 19-28.
-
(2007)
J Bone Miner Res
, vol.22
, pp. 19-28
-
-
van Bezooijen, R.L.1
Svensson, J.P.2
Eefting, D.3
Visser, A.4
van der, H.G.5
-
51
-
-
0028284556
-
Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist
-
Willnow TE, Sheng Z, Ishibashi S, Herz J (1994) Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist. Science 264: 1471-1474.
-
(1994)
Science
, vol.264
, pp. 1471-1474
-
-
Willnow, T.E.1
Sheng, Z.2
Ishibashi, S.3
Herz, J.4
-
52
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, et al. (2000) Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100: 197-207.
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.F.5
-
53
-
-
46649107327
-
Inhibition of beta-catenin signaling causes defects in postnatal cartilage development
-
Chen M, Zhu M, Awad H, Li TF, Sheu TJ, et al. (2008) Inhibition of beta-catenin signaling causes defects in postnatal cartilage development. J Cell Sci 121: 1455-1465.
-
(2008)
J Cell Sci
, vol.121
, pp. 1455-1465
-
-
Chen, M.1
Zhu, M.2
Awad, H.3
Li, T.F.4
Sheu, T.J.5
-
54
-
-
41149142409
-
Wnt/beta-catenin signaling regulates cranial base development and growth
-
Nagayama M, Iwamoto M, Hargett A, Kamiya N, Tamamura Y, et al. (2008) Wnt/beta-catenin signaling regulates cranial base development and growth. J Dent Res 87: 244-249.
-
(2008)
J Dent Res
, vol.87
, pp. 244-249
-
-
Nagayama, M.1
Iwamoto, M.2
Hargett, A.3
Kamiya, N.4
Tamamura, Y.5
-
55
-
-
29144529005
-
BMP signaling stimulates cellular differentiation at multiple steps during cartilage development
-
Kobayashi T, Lyons KM, McMahon AP, Kronenberg HM (2005) BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proc Natl Acad Sci U S A 102: 18023-18027.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18023-18027
-
-
Kobayashi, T.1
Lyons, K.M.2
McMahon, A.P.3
Kronenberg, H.M.4
-
57
-
-
0037432766
-
-
Boucher P, Gotthardt M, Li WP, Anderson RG, Herz J (2003) LRP: role in vascular wall integrity and protection from atherosclerosis. Science 300: 329-332.
-
Boucher P, Gotthardt M, Li WP, Anderson RG, Herz J (2003) LRP: role in vascular wall integrity and protection from atherosclerosis. Science 300: 329-332.
-
-
-
-
58
-
-
44149093500
-
LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: Implications for Marfan syndrome
-
Boucher P, Li WP, Matz RL, Takayama Y, Auwerx J, et al. (2007) LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome. PLoS One 2: e448.
-
(2007)
PLoS One
, vol.2
-
-
Boucher, P.1
Li, W.P.2
Matz, R.L.3
Takayama, Y.4
Auwerx, J.5
-
59
-
-
70349093134
-
LRP1 regulates architecture of the vascular wall by controlling PDGFRβ-dependent phosphatidylinositol 3-kinase activation
-
Zhou L, Takayama Y, Boucher P, Tallquist MD, Herz J (2009) LRP1 regulates architecture of the vascular wall by controlling PDGFRβ-dependent phosphatidylinositol 3-kinase activation. PLoS One 4: e6922.
-
(2009)
PLoS One
, vol.4
-
-
Zhou, L.1
Takayama, Y.2
Boucher, P.3
Tallquist, M.D.4
Herz, J.5
-
60
-
-
20244373613
-
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
-
Glass DA, Bialek P, Ahn JD, Starbuck M, Patel MS, et al. (2005) Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell 8: 751-764.
-
(2005)
Dev Cell
, vol.8
, pp. 751-764
-
-
Glass, D.A.1
Bialek, P.2
Ahn, J.D.3
Starbuck, M.4
Patel, M.S.5
-
61
-
-
34547690686
-
Endocrine regulation of energy metabolism by the skeleton
-
Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, et al. (2007) Endocrine regulation of energy metabolism by the skeleton. Cell 130: 456-469.
-
(2007)
Cell
, vol.130
, pp. 456-469
-
-
Lee, N.K.1
Sowa, H.2
Hinoi, E.3
Ferron, M.4
Ahn, J.D.5
|