메뉴 건너뛰기




Volumn 11, Issue 21, 2005, Pages 7599-7606

The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD45 ANTIGEN; DEXAMETHASONE; INTERLEUKIN 6; SYNDECAN 1;

EID: 27744526844     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-0523     Document Type: Article
Times cited : (71)

References (50)
  • 1
    • 0037961737 scopus 로고    scopus 로고
    • Stem-cell "plasticity": Befuddled by the muddle
    • Goodell MA. Stem-cell "plasticity": befuddled by the muddle. Curr Opin Hematol 2003;10:208-13.
    • (2003) Curr Opin Hematol , vol.10 , pp. 208-213
    • Goodell, M.A.1
  • 2
    • 1542328965 scopus 로고    scopus 로고
    • Plasticity of adult stem cells
    • Wagers AJ, Weissman IL. Plasticity of adult stem cells. Cell 2004;116:639-48.
    • (2004) Cell , vol.116 , pp. 639-648
    • Wagers, A.J.1    Weissman, I.L.2
  • 3
    • 1842527031 scopus 로고    scopus 로고
    • Environmental guidance of normal and tumor cell plasticity: Epithelial mesenchymal transitions as a paradigm
    • Prindull G, Zipori D. Environmental guidance of normal and tumor cell plasticity: epithelial mesenchymal transitions as a paradigm. Blood 2004;105:2892-9.
    • (2004) Blood , vol.105 , pp. 2892-2899
    • Prindull, G.1    Zipori, D.2
  • 5
    • 0037606041 scopus 로고    scopus 로고
    • Multiple myeloma tumor progression in the 5T2MM murine model is a multistage and dynamic process of differentiation, proliferation, invasion, and apoptosis
    • Asosingh K, De Raeve H, Van Riet I, Van Camp B, Vanderkerken K. Multiple myeloma tumor progression in the 5T2MM murine model is a multistage and dynamic process of differentiation, proliferation, invasion, and apoptosis. Blood 2003;101:3136-41.
    • (2003) Blood , vol.101 , pp. 3136-3141
    • Asosingh, K.1    De Raeve, H.2    Van Riet, I.3    Van Camp, B.4    Vanderkerken, K.5
  • 6
    • 0038336720 scopus 로고    scopus 로고
    • A cellular model for myeloma cell growth and maturation based on an intraclonal CD45 hierarchy
    • Bataille R, Robillard N, Pellat-Deceunynck C, Amiot M. A cellular model for myeloma cell growth and maturation based on an intraclonal CD45 hierarchy. Immunol Rev 2003;194:105-11.
    • (2003) Immunol Rev , vol.194 , pp. 105-111
    • Bataille, R.1    Robillard, N.2    Pellat-Deceunynck, C.3    Amiot, M.4
  • 8
  • 9
    • 0025885099 scopus 로고
    • Role of bone marrow stromal cells in the growth of human multiple myeloma
    • Caligaris-Cappio F, Bergui L, Gregoretti MG, et al. Role of bone marrow stromal cells in the growth of human multiple myeloma. Blood 1991;77:2688-93.
    • (1991) Blood , vol.77 , pp. 2688-2693
    • Caligaris-Cappio, F.1    Bergui, L.2    Gregoretti, M.G.3
  • 10
    • 0027369935 scopus 로고
    • Detection of circulating tumor cells in multiple myeloma by a PCR-based method
    • Corradini P, Voena C, Omede P, et al. Detection of circulating tumor cells in multiple myeloma by a PCR-based method. Leukemia 1993;7:1879-82.
    • (1993) Leukemia , vol.7 , pp. 1879-1882
    • Corradini, P.1    Voena, C.2    Omede, P.3
  • 11
    • 0028908877 scopus 로고
    • + peripheral blood cells expressing CD38, CD56, and monotypic Ig light chain
    • + peripheral blood cells expressing CD38, CD56, and monotypic Ig light chain. Blood 1995;85:436-47.
    • (1995) Blood , vol.85 , pp. 436-447
    • Bergsagel, P.L.1    Smith, A.M.2    Szczepek, A.3
  • 12
    • 0030049654 scopus 로고    scopus 로고
    • Circulating clonal lymphocytes in myeloma constitute a minor subpopulation of B cells
    • Chen BJ, Epstein J. Circulating clonal lymphocytes in myeloma constitute a minor subpopulation of B cells. Blood 1996;87:1972-6.
    • (1996) Blood , vol.87 , pp. 1972-1976
    • Chen, B.J.1    Epstein, J.2
  • 13
    • 0033977906 scopus 로고    scopus 로고
    • In multiple myeloma, circulating hyperdiploid B cells have clonotypic immunoglobulin heavy chain rearrangements and may mediate spread of disease
    • Pilarski LM, Giannakopoulos NV, Szczepek AJ, et al. In multiple myeloma, circulating hyperdiploid B cells have clonotypic immunoglobulin heavy chain rearrangements and may mediate spread of disease. Clin Cancer Res 2000;6:585-96.
    • (2000) Clin Cancer Res , vol.6 , pp. 585-596
    • Pilarski, L.M.1    Giannakopoulos, N.V.2    Szczepek, A.J.3
  • 14
    • 0036794974 scopus 로고    scopus 로고
    • Clonotypic myeloma cells able to xenograft myeloma to nonobese diabetic severe combined immunodeficient mice copurify with CD34 (+) hematopoietic progenitors
    • Pilarski LM, Belch AR. Clonotypic myeloma cells able to xenograft myeloma to nonobese diabetic severe combined immunodeficient mice copurify with CD34 (+) hematopoietic progenitors. Clin Cancer Res 2002;8:3198-204.
    • (2002) Clin Cancer Res , vol.8 , pp. 3198-3204
    • Pilarski, L.M.1    Belch, A.R.2
  • 15
    • 0035525742 scopus 로고    scopus 로고
    • Persistent preswitch clonotypic myeloma cells correlate with decreased survival: Evidence for isotype switching within the myeloma clone
    • Reiman T, Seeberger K, Taylor BJ, et al. Persistent preswitch clonotypic myeloma cells correlate with decreased survival: evidence for isotype switching within the myeloma clone. Blood 2001;98:2791-9.
    • (2001) Blood , vol.98 , pp. 2791-2799
    • Reiman, T.1    Seeberger, K.2    Taylor, B.J.3
  • 16
    • 0030015735 scopus 로고    scopus 로고
    • The labeling index of primitive plasma cells determines the clinical behaviour of patients with myelomatosis
    • Joshua D, Petersen A, Brown R, et al. The labeling index of primitive plasma cells determines the clinical behaviour of patients with myelomatosis. Br J Haematol 1996;94:76-81.
    • (1996) Br J Haematol , vol.94 , pp. 76-81
    • Joshua, D.1    Petersen, A.2    Brown, R.3
  • 17
    • 1542360757 scopus 로고    scopus 로고
    • Normal and malignant human plasma cells: Proliferation, differentiation, and expansions in relation to CD45 expression
    • Pellat-Deceunynck C, Bataille R. Normal and malignant human plasma cells: proliferation, differentiation, and expansions in relation to CD45 expression. Blood Cells Mol Dis 2004;32:293-301.
    • (2004) Blood Cells Mol Dis , vol.32 , pp. 293-301
    • Pellat-Deceunynck, C.1    Bataille, R.2
  • 18
    • 0033570946 scopus 로고    scopus 로고
    • The proliferative potential of myeloma plasma cells manifest in the SCID-hu host
    • Yaccoby S, Epstein J. The proliferative potential of myeloma plasma cells manifest in the SCID-hu host. Blood 1999;94:3576-82.
    • (1999) Blood , vol.94 , pp. 3576-3582
    • Yaccoby, S.1    Epstein, J.2
  • 19
    • 8844264524 scopus 로고    scopus 로고
    • The SCID-rab model: A novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells
    • Yata K, Yaccoby S. The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells. Leukemia 2004;18:1891-7.
    • (2004) Leukemia , vol.18 , pp. 1891-1897
    • Yata, K.1    Yaccoby, S.2
  • 20
    • 0038070078 scopus 로고    scopus 로고
    • Delayed in vivo disease progression is associated with high proportions of CD45+ myeloma cells in the 5T2MM murine model
    • Asosingh K, Willems A, Van Riet I, Van Camp B, Vanderkerken K. Delayed in vivo disease progression is associated with high proportions of CD45+ myeloma cells in the 5T2MM murine model. Cancer Res 2003;63:3019-20.
    • (2003) Cancer Res , vol.63 , pp. 3019-3020
    • Asosingh, K.1    Willems, A.2    Van Riet, I.3    Van Camp, B.4    Vanderkerken, K.5
  • 21
    • 0036459199 scopus 로고    scopus 로고
    • Mechanisms involved in the differential bone marrow homing of CD45 subsets in 5T murine models of myeloma
    • Asosingh K, Menu E, Van Valckenborgh E, et al. Mechanisms involved in the differential bone marrow homing of CD45 subsets in 5T murine models of myeloma. Clin Exp Metastasis 2002;19:583-91.
    • (2002) Clin Exp Metastasis , vol.19 , pp. 583-591
    • Asosingh, K.1    Menu, E.2    Van Valckenborgh, E.3
  • 22
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-7.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 23
    • 1542283717 scopus 로고    scopus 로고
    • Characterization of clonogenic multiple myeloma cells
    • Matsui W, Huff CA, Wang Q, et al. Characterization of clonogenic multiple myeloma cells. Blood 2004;103:2332-6.
    • (2004) Blood , vol.103 , pp. 2332-2336
    • Matsui, W.1    Huff, C.A.2    Wang, Q.3
  • 25
    • 0036894648 scopus 로고    scopus 로고
    • A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells
    • Tsai RY, McKay RD. A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. Genes Dev 2002;16:2991-3003.
    • (2002) Genes Dev , vol.16 , pp. 2991-3003
    • Tsai, R.Y.1    McKay, R.D.2
  • 26
  • 27
    • 18144451007 scopus 로고    scopus 로고
    • New insights in myeloma-induced osteolysis
    • Barille-Nion S, Bataille R. New insights in myeloma-induced osteolysis. Leuk Lymphoma 2003;44:1463-7.
    • (2003) Leuk Lymphoma , vol.44 , pp. 1463-1467
    • Barille-Nion, S.1    Bataille, R.2
  • 29
    • 0141482103 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor-κB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo
    • Farrugia AN, Atkins GJ, To LB, et al. Receptor activator of nuclear factor-κB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo. Cancer Res 2003;63:5438-45.
    • (2003) Cancer Res , vol.63 , pp. 5438-5445
    • Farrugia, A.N.1    Atkins, G.J.2    To, L.B.3
  • 30
    • 0035895055 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma
    • Croucher PI, Shipman CM, Lippitt J, et al. Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma. Blood 2001;98:3534-40.
    • (2001) Blood , vol.98 , pp. 3534-3540
    • Croucher, P.I.1    Shipman, C.M.2    Lippitt, J.3
  • 31
    • 0037389602 scopus 로고    scopus 로고
    • Expression of receptor activator of nuclear factor κB ligand on bone marrow plasma cells correlates with osteolytic bone disease in patients with multiple myeloma
    • Heider U, Langelotz C, Jakob C, et al. Expression of receptor activator of nuclear factor κB ligand on bone marrow plasma cells correlates with osteolytic bone disease in patients with multiple myeloma. Clin Cancer Res 2003;9:1436-40.
    • (2003) Clin Cancer Res , vol.9 , pp. 1436-1440
    • Heider, U.1    Langelotz, C.2    Jakob, C.3
  • 32
    • 1542720384 scopus 로고    scopus 로고
    • Cancer and the microenvironment: Myeloma-osteoclast interactions as a model
    • Yaccoby S, Wezeman MJ, Henderson A, et al. Cancer and the microenvironment: myeloma-osteoclast interactions as a model. Cancer Res 2004;64:2016-23.
    • (2004) Cancer Res , vol.64 , pp. 2016-2023
    • Yaccoby, S.1    Wezeman, M.J.2    Henderson, A.3
  • 33
    • 0035949510 scopus 로고    scopus 로고
    • Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression
    • Pearse RN, Sordillo EM, Yaccoby S, et al. Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. Proc Natl Acad Sci U S A 2001;98:11581-6.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11581-11586
    • Pearse, R.N.1    Sordillo, E.M.2    Yaccoby, S.3
  • 34
    • 0035895083 scopus 로고    scopus 로고
    • Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment
    • Giuliani N, Bataille R, Mancini C, Lazzaretti M, Barille S. Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment. Blood 2001;98:3527-33.
    • (2001) Blood , vol.98 , pp. 3527-3533
    • Giuliani, N.1    Bataille, R.2    Mancini, C.3    Lazzaretti, M.4    Barille, S.5
  • 35
    • 0342322717 scopus 로고    scopus 로고
    • Macrophage inflammatory protein 1-α is a potential osteoclast stimulatory factor in multiple myeloma
    • Choi SJ, Cruz JC, Craig F, et al. Macrophage inflammatory protein 1-α is a potential osteoclast stimulatory factor in multiple myeloma. Blood 2000;96:671-5.
    • (2000) Blood , vol.96 , pp. 671-675
    • Choi, S.J.1    Cruz, J.C.2    Craig, F.3
  • 36
    • 0346363760 scopus 로고    scopus 로고
    • The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
    • Tian E, Zhan F, Walker R, et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 2003;349:2483-94.
    • (2003) N Engl J Med , vol.349 , pp. 2483-2494
    • Tian, E.1    Zhan, F.2    Walker, R.3
  • 37
    • 0031782314 scopus 로고    scopus 로고
    • Anti-myeloma activity of pamidronate in vivo
    • Dhodapkar MV, Singh J, Mehta J, et al. Anti-myeloma activity of pamidronate in vivo. Br J Haematol 1998;103:530-2.
    • (1998) Br J Haematol , vol.103 , pp. 530-532
    • Dhodapkar, M.V.1    Singh, J.2    Mehta, J.3
  • 38
    • 9044219839 scopus 로고    scopus 로고
    • Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma
    • Myeloma Aredia Study Group
    • Berenson JR, Lichtenstein A, Porter L, et al. Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group. N Engl J Med 1996;334:488-93.
    • (1996) N Engl J Med , vol.334 , pp. 488-493
    • Berenson, J.R.1    Lichtenstein, A.2    Porter, L.3
  • 39
    • 0036181668 scopus 로고    scopus 로고
    • Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity
    • Yaccoby S, Pearse RN, Johnson CL, et al. Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity. Br J Haematol 2002;116:278-90.
    • (2002) Br J Haematol , vol.116 , pp. 278-290
    • Yaccoby, S.1    Pearse, R.N.2    Johnson, C.L.3
  • 40
    • 0242308942 scopus 로고    scopus 로고
    • Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: Evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival
    • Croucher PI, De Hendrik R, Perry MJ, et al. Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival. J Bone Miner Res 2003;18:482-92.
    • (2003) J Bone Miner Res , vol.18 , pp. 482-492
    • Croucher, P.I.1    De Hendrik, R.2    Perry, M.J.3
  • 41
    • 0037439916 scopus 로고    scopus 로고
    • Recombinant osteoprotegerin decreases tumor burden and increases survival in a murine model of multiple myeloma
    • Vanderkerken K, De Leenheer E, Shipman C, et al. Recombinant osteoprotegerin decreases tumor burden and increases survival in a murine model of multiple myeloma. Cancer Res 2003;63:287-9.
    • (2003) Cancer Res , vol.63 , pp. 287-289
    • Vanderkerken, K.1    De Leenheer, E.2    Shipman, C.3
  • 42
    • 0032533909 scopus 로고    scopus 로고
    • Induction of CD45 expression and proliferation in U-266 myeloma cell line by interleukin-6
    • Mahmoud MS, Ishikawa H, Fujii R, Kawano MM. Induction of CD45 expression and proliferation in U-266 myeloma cell line by interleukin-6. Blood 1998;92:3887-97.
    • (1998) Blood , vol.92 , pp. 3887-3897
    • Mahmoud, M.S.1    Ishikawa, H.2    Fujii, R.3    Kawano, M.M.4
  • 43
    • 0038235872 scopus 로고    scopus 로고
    • Interleukin-6, CD45 and the src-kinases in myeloma cell proliferation
    • Ishikawa H, Tsuyama N, Abroun S, et al. Interleukin-6, CD45 and the src-kinases in myeloma cell proliferation. Leuk Lymphoma 2003;44:1477-81.
    • (2003) Leuk Lymphoma , vol.44 , pp. 1477-1481
    • Ishikawa, H.1    Tsuyama, N.2    Abroun, S.3
  • 44
    • 0031781636 scopus 로고    scopus 로고
    • The bone marrow stromal environment is a major factor in myeloma cell resistance to dexamethasone
    • Grigorieva I, Thomas X, Epstein J. The bone marrow stromal environment is a major factor in myeloma cell resistance to dexamethasone. Exp Hematol 1998;26:597-603.
    • (1998) Exp Hematol , vol.26 , pp. 597-603
    • Grigorieva, I.1    Thomas, X.2    Epstein, J.3
  • 45
    • 0035353176 scopus 로고    scopus 로고
    • Reciprocal expression of CD38 and CD34 by adult murine hematopoietic stem cells
    • Tajima F, Deguchi T, Laver JH, Zeng H, Ogawa M. Reciprocal expression of CD38 and CD34 by adult murine hematopoietic stem cells. Blood 2001;97:2618-24.
    • (2001) Blood , vol.97 , pp. 2618-2624
    • Tajima, F.1    Deguchi, T.2    Laver, J.H.3    Zeng, H.4    Ogawa, M.5
  • 46
    • 4944230728 scopus 로고    scopus 로고
    • Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: A vicious cycle between bone destruction and myeloma expansion
    • Abe M, Hiura K, Wilde J, et al. Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion. Blood 2004;104:2484-91.
    • (2004) Blood , vol.104 , pp. 2484-2491
    • Abe, M.1    Hiura, K.2    Wilde, J.3
  • 49
    • 0041507106 scopus 로고    scopus 로고
    • Interleukin-6-induced proliferation of human myeloma cells associated with CD45 molecules
    • Ishikawa H, Tsuyama N, Kawano MM. Interleukin-6-induced proliferation of human myeloma cells associated with CD45 molecules. Int J Hematol 2003;78:95-105.
    • (2003) Int J Hematol , vol.78 , pp. 95-105
    • Ishikawa, H.1    Tsuyama, N.2    Kawano, M.M.3
  • 50
    • 2542496938 scopus 로고    scopus 로고
    • Patients with CD45 negative multiple myeloma receiving high-dose therapy have a shorter survival than those with CD45 positive multiple myeloma
    • Moreau P, Robillard N, Avet-Loiseau H, et al. Patients with CD45 negative multiple myeloma receiving high-dose therapy have a shorter survival than those with CD45 positive multiple myeloma. Haematologica 2004;89:547-51.
    • (2004) Haematologica , vol.89 , pp. 547-551
    • Moreau, P.1    Robillard, N.2    Avet-Loiseau, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.