-
1
-
-
0033027858
-
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
-
Gerber H.P., Vu T.H., Ryan A.M., Kowalski J., Werb Z., and Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat. Med. 5 (1999) 623-628
-
(1999)
Nat. Med.
, vol.5
, pp. 623-628
-
-
Gerber, H.P.1
Vu, T.H.2
Ryan, A.M.3
Kowalski, J.4
Werb, Z.5
Ferrara, N.6
-
2
-
-
0036738338
-
Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4
-
Peng H., Wright V., Usas A., Gearhart B., Shen H.C., Cummins J., and Huard J. Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. J. Clin. Invest. 110 (2002) 751-759
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 751-759
-
-
Peng, H.1
Wright, V.2
Usas, A.3
Gearhart, B.4
Shen, H.C.5
Cummins, J.6
Huard, J.7
-
3
-
-
0036808899
-
Muscle-based gene therapy and tissue engineering to improve bone healing
-
Young B.H., Peng H., and Huard J. Muscle-based gene therapy and tissue engineering to improve bone healing. Clin. Orthop. Relat. Res. (2002) S243-251
-
(2002)
Clin. Orthop. Relat. Res.
-
-
Young, B.H.1
Peng, H.2
Huard, J.3
-
4
-
-
37549069399
-
Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts
-
Tang C.H., Yang R.S., Chien M.Y., Chen C.C., and Fu W.M. Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts. Eur. J. Pharmacol. 579 (2008) 40-49
-
(2008)
Eur. J. Pharmacol.
, vol.579
, pp. 40-49
-
-
Tang, C.H.1
Yang, R.S.2
Chien, M.Y.3
Chen, C.C.4
Fu, W.M.5
-
5
-
-
0033793881
-
VEGF gene therapy: stimulating angiogenesis or angioma-genesis?
-
Carmeliet P. VEGF gene therapy: stimulating angiogenesis or angioma-genesis?. Nat. Med. 6 (2000) 1102-1103
-
(2000)
Nat. Med.
, vol.6
, pp. 1102-1103
-
-
Carmeliet, P.1
-
6
-
-
0033134604
-
Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization
-
Isner J.M., and Asahara T. Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization. J. Clin. Invest. 103 (1999) 1231-1236
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1231-1236
-
-
Isner, J.M.1
Asahara, T.2
-
7
-
-
0032504752
-
Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization
-
Asahara T., Chen D., Takahashi T., Fujikawa K., Kearney M., Magner M., Yancopoulos G.D., and Isner J.M. Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ. Res. 83 (1998) 233-240
-
(1998)
Circ. Res.
, vol.83
, pp. 233-240
-
-
Asahara, T.1
Chen, D.2
Takahashi, T.3
Fujikawa, K.4
Kearney, M.5
Magner, M.6
Yancopoulos, G.D.7
Isner, J.M.8
-
8
-
-
0033601357
-
Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1
-
Thurston G., Suri C., Smith K., McClain J., Sato T.N., Yancopoulos G.D., and McDonald D.M. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 286 (1999) 2511-2514
-
(1999)
Science
, vol.286
, pp. 2511-2514
-
-
Thurston, G.1
Suri, C.2
Smith, K.3
McClain, J.4
Sato, T.N.5
Yancopoulos, G.D.6
McDonald, D.M.7
-
9
-
-
11144357304
-
COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity
-
Cho C.H., Kammerer R.A., Lee H.J., Steinmetz M.O., Ryu Y.S., Lee S.H., Yasunaga K., Kim K.T., Kim I., Choi H.H., Kim W., Kim S.H., Park S.K., Lee G.M., and Koh G.Y. COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 5547-5552
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 5547-5552
-
-
Cho, C.H.1
Kammerer, R.A.2
Lee, H.J.3
Steinmetz, M.O.4
Ryu, Y.S.5
Lee, S.H.6
Yasunaga, K.7
Kim, K.T.8
Kim, I.9
Choi, H.H.10
Kim, W.11
Kim, S.H.12
Park, S.K.13
Lee, G.M.14
Koh, G.Y.15
-
10
-
-
0006677050
-
Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3(-Kinase/Akt signal transduction pathway
-
Kim I., Kim H.G., So J.N., Kim J.H., Kwak H.J., and Koh G.Y. Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3(-Kinase/Akt signal transduction pathway. Circ. Res. 86 (2000) 24-29
-
(2000)
Circ. Res.
, vol.86
, pp. 24-29
-
-
Kim, I.1
Kim, H.G.2
So, J.N.3
Kim, J.H.4
Kwak, H.J.5
Koh, G.Y.6
-
11
-
-
21244434808
-
Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2
-
Kim K.T., Choi H.H., Steinmetz M.O., Maco B., Kammerer R.A., Ahn S.Y., Kim H.Z., Lee G.M., and Koh G.Y. Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2. J. Biol. Chem. 280 (2005) 20126-20131
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20126-20131
-
-
Kim, K.T.1
Choi, H.H.2
Steinmetz, M.O.3
Maco, B.4
Kammerer, R.A.5
Ahn, S.Y.6
Kim, H.Z.7
Lee, G.M.8
Koh, G.Y.9
-
12
-
-
33645508703
-
COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model
-
Cho C.H., Sung H.K., Kim K.T., Cheon H.G., Oh G.T., Hong H.J., Yoo O.J., and Koh G.Y. COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 4946-4951
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 4946-4951
-
-
Cho, C.H.1
Sung, H.K.2
Kim, K.T.3
Cheon, H.G.4
Oh, G.T.5
Hong, H.J.6
Yoo, O.J.7
Koh, G.Y.8
-
13
-
-
0032514135
-
Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages
-
Chen D., Ji X., Harris M.A., Feng J.Q., Karsenty G., Celeste A.J., Rosen V., Mundy G.R., and Harris S.E. Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages. J. Cell. Biol. 142 (1998) 295-305
-
(1998)
J. Cell. Biol.
, vol.142
, pp. 295-305
-
-
Chen, D.1
Ji, X.2
Harris, M.A.3
Feng, J.Q.4
Karsenty, G.5
Celeste, A.J.6
Rosen, V.7
Mundy, G.R.8
Harris, S.E.9
-
14
-
-
0027946689
-
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage
-
Katagiri T., Yamaguchi A., Komaki M., Abe E., Takahashi N., Ikeda T., Rosen V., Wozney J.M., Fujisawa-Sehara A., and Suda T. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J. Cell. Biol. 127 (1994) 1755-1766
-
(1994)
J. Cell. Biol.
, vol.127
, pp. 1755-1766
-
-
Katagiri, T.1
Yamaguchi, A.2
Komaki, M.3
Abe, E.4
Takahashi, N.5
Ikeda, T.6
Rosen, V.7
Wozney, J.M.8
Fujisawa-Sehara, A.9
Suda, T.10
-
15
-
-
2542479890
-
Signal transduction and biological functions of bone morphogenetic proteins
-
Chen D., Zhao M., Harris S.E., and Mi Z. Signal transduction and biological functions of bone morphogenetic proteins. Front. Biosci. 9 (2004) 349-358
-
(2004)
Front. Biosci.
, vol.9
, pp. 349-358
-
-
Chen, D.1
Zhao, M.2
Harris, S.E.3
Mi, Z.4
-
17
-
-
0037031854
-
Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription
-
Ghosh-Choudhury N., Abboud S.L., Nishimura R., Celeste A., Mahimainathan L., and Choudhury G.G. Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription. J. Biol. Chem. 277 (2002) 33361-33368
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33361-33368
-
-
Ghosh-Choudhury, N.1
Abboud, S.L.2
Nishimura, R.3
Celeste, A.4
Mahimainathan, L.5
Choudhury, G.G.6
-
18
-
-
34548559194
-
Osteoblast-specific Angiopoietin 1 overexpression increases bone mass
-
Suzuki T., Miyamoto T., Fujita N., Ninomiya K., Iwasaki R., Toyama Y., and Suda T. Osteoblast-specific Angiopoietin 1 overexpression increases bone mass. Biochem. Biophys. Res. Commun. 362 (2007) 1019-1025
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.362
, pp. 1019-1025
-
-
Suzuki, T.1
Miyamoto, T.2
Fujita, N.3
Ninomiya, K.4
Iwasaki, R.5
Toyama, Y.6
Suda, T.7
-
19
-
-
44349086379
-
COMP-Ang1, angiopoietin-1 variant protects radiation-induced bone marrow damage in C57BL/6 mice
-
Lee H.J., Bae S.W., Koh G.Y., and Lee Y.S. COMP-Ang1, angiopoietin-1 variant protects radiation-induced bone marrow damage in C57BL/6 mice. J. Radiat. Res. (Tokyo) 49 (2008) 313-320
-
(2008)
J. Radiat. Res. (Tokyo)
, vol.49
, pp. 313-320
-
-
Lee, H.J.1
Bae, S.W.2
Koh, G.Y.3
Lee, Y.S.4
-
20
-
-
0030776315
-
Dependence of mesenchymal cell responses on duration of exposure to bone morphogenetic protein-2 in vitro
-
Puleo D.A. Dependence of mesenchymal cell responses on duration of exposure to bone morphogenetic protein-2 in vitro. J. Cell. Physiol. 173 (1997) 93-101
-
(1997)
J. Cell. Physiol.
, vol.173
, pp. 93-101
-
-
Puleo, D.A.1
-
21
-
-
3142731900
-
Osteoinduction by bone morphogenetic protein 2-expressing adenoviral vector: application of biomaterial to mask the host immune response
-
Sonobe J., Okubo Y., Kaihara S., Miyatake S., and Bessho K. Osteoinduction by bone morphogenetic protein 2-expressing adenoviral vector: application of biomaterial to mask the host immune response. Hum. Gene. Ther. 15 (2004) 659-668
-
(2004)
Hum. Gene. Ther.
, vol.15
, pp. 659-668
-
-
Sonobe, J.1
Okubo, Y.2
Kaihara, S.3
Miyatake, S.4
Bessho, K.5
-
22
-
-
67649831233
-
The orphan nuclear receptor estrogen receptor-related receptor gamma negatively regulates BMP2-induced osteoblast differentiation and bone formation
-
Jeong B.C., Lee Y.S., Park Y.Y., Bae I.H., Kim D.K., Koo S.H., Choi H.R., Kim S.H., Franceschi R.T., Koh J.T., and Choi H.S. The orphan nuclear receptor estrogen receptor-related receptor gamma negatively regulates BMP2-induced osteoblast differentiation and bone formation. J. Biol. Chem. 284 (2009) 14211-14218
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 14211-14218
-
-
Jeong, B.C.1
Lee, Y.S.2
Park, Y.Y.3
Bae, I.H.4
Kim, D.K.5
Koo, S.H.6
Choi, H.R.7
Kim, S.H.8
Franceschi, R.T.9
Koh, J.T.10
Choi, H.S.11
-
23
-
-
27444446737
-
VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis
-
Peng H., Usas A., Olshanski A., Ho A.M., Gearhart B., Cooper G.M., and Huard J. VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. J. Bone Miner. Res. 20 (2005) 2017-2027
-
(2005)
J. Bone Miner. Res.
, vol.20
, pp. 2017-2027
-
-
Peng, H.1
Usas, A.2
Olshanski, A.3
Ho, A.M.4
Gearhart, B.5
Cooper, G.M.6
Huard, J.7
-
24
-
-
0034993673
-
Exogenously regulated stem cell-mediated gene therapy for bone regeneration
-
Moutsatsos I.K., Turgeman G., Zhou S., Kurkalli B.G., Pelled G., Tzur L., Kelley P., Stumm N., Mi S., Muller R., Zilberman Y., and Gazit D. Exogenously regulated stem cell-mediated gene therapy for bone regeneration. Mol. Ther. 3 (2001) 449-461
-
(2001)
Mol. Ther.
, vol.3
, pp. 449-461
-
-
Moutsatsos, I.K.1
Turgeman, G.2
Zhou, S.3
Kurkalli, B.G.4
Pelled, G.5
Tzur, L.6
Kelley, P.7
Stumm, N.8
Mi, S.9
Muller, R.10
Zilberman, Y.11
Gazit, D.12
-
25
-
-
0024256133
-
Novel regulators of bone formation: molecular clones and activities
-
Wozney J.M., Rosen V., Celeste A.J., Mitsock L.M., Whitters M.J., Kriz R.W., Hewick R.M., and Wang E.A. Novel regulators of bone formation: molecular clones and activities. Science 242 (1988) 1528-1534
-
(1988)
Science
, vol.242
, pp. 1528-1534
-
-
Wozney, J.M.1
Rosen, V.2
Celeste, A.J.3
Mitsock, L.M.4
Whitters, M.J.5
Kriz, R.W.6
Hewick, R.M.7
Wang, E.A.8
-
26
-
-
0242664611
-
Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation
-
Guicheux J., Lemonnier J., Ghayor C., Suzuki A., Palmer G., and Caverzasio J. Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation. J. Bone Miner. Res. 18 (2003) 2060-2068
-
(2003)
J. Bone Miner. Res.
, vol.18
, pp. 2060-2068
-
-
Guicheux, J.1
Lemonnier, J.2
Ghayor, C.3
Suzuki, A.4
Palmer, G.5
Caverzasio, J.6
-
27
-
-
0035700994
-
Divergent regulation by p44/p42 MAP kinase and p38 MAP kinase of bone morphogenetic protein-4-stimulated osteocalcin synthesis in osteoblasts
-
Kozawa O., Hatakeyama D., and Uematsu T. Divergent regulation by p44/p42 MAP kinase and p38 MAP kinase of bone morphogenetic protein-4-stimulated osteocalcin synthesis in osteoblasts. J. Cell. Biochem. 84 (2002) 583-589
-
(2002)
J. Cell. Biochem.
, vol.84
, pp. 583-589
-
-
Kozawa, O.1
Hatakeyama, D.2
Uematsu, T.3
-
28
-
-
27644484777
-
BMP-2 prevents apoptosis of the N1511 chondrocytic cell line through PI3K/Akt-mediated NF-kappaB activation
-
Sugimori K., Matsui K., Motomura H., Tokoro T., Wang J., Higa S., Kimura T., and Kitajima I. BMP-2 prevents apoptosis of the N1511 chondrocytic cell line through PI3K/Akt-mediated NF-kappaB activation. J. Bone Miner. Metab. 23 (2005) 411-419
-
(2005)
J. Bone Miner. Metab.
, vol.23
, pp. 411-419
-
-
Sugimori, K.1
Matsui, K.2
Motomura, H.3
Tokoro, T.4
Wang, J.5
Higa, S.6
Kimura, T.7
Kitajima, I.8
-
29
-
-
0037188941
-
Role of Akt signaling in vascular homeostasis and angiogenesis
-
Shiojima I., and Walsh K. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ. Res. 90 (2002) 1243-1250
-
(2002)
Circ. Res.
, vol.90
, pp. 1243-1250
-
-
Shiojima, I.1
Walsh, K.2
-
30
-
-
33748769772
-
Expression of angiopoietins and their receptor Tie2 in the bone marrow of patients with acute myeloid leukemia
-
Schliemann C., Bieker R., Padro T., Kessler T., Hintelmann H., Buchner T., Berdel W.E., and Mesters R.M. Expression of angiopoietins and their receptor Tie2 in the bone marrow of patients with acute myeloid leukemia. Haematologica 91 (2006) 1203-1211
-
(2006)
Haematologica
, vol.91
, pp. 1203-1211
-
-
Schliemann, C.1
Bieker, R.2
Padro, T.3
Kessler, T.4
Hintelmann, H.5
Buchner, T.6
Berdel, W.E.7
Mesters, R.M.8
-
31
-
-
0027326213
-
Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells
-
Iwama A., Hamaguchi I., Hashiyama M., Murayama Y., Yasunaga K., and Suda T. Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells. Biochem. Biophys. Res. Commun. 195 (1993) 301-309
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.195
, pp. 301-309
-
-
Iwama, A.1
Hamaguchi, I.2
Hashiyama, M.3
Murayama, Y.4
Yasunaga, K.5
Suda, T.6
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