메뉴 건너뛰기




Volumn 5, Issue 12, 2010, Pages

Coordinated translocation of mammalian gli proteins and suppressor of fused to the primary cilium

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA; REGULATOR PROTEIN; SONIC HEDGEHOG PROTEIN; SUPPRESSOR OF FUSED PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; GLI1 PROTEIN, HUMAN; GLI3 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; NERVE PROTEIN; REPRESSOR PROTEIN; SUFU PROTEIN, MOUSE;

EID: 78650808301     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015900     Document Type: Article
Times cited : (60)

References (49)
  • 1
    • 57049089995 scopus 로고    scopus 로고
    • Hedgehog signaling in development and cancer
    • Jiang J, Hui CC (2008) Hedgehog signaling in development and cancer. Dev Cell 15: 801-812.
    • (2008) Dev Cell , vol.15 , pp. 801-812
    • Jiang, J.1    Hui, C.C.2
  • 2
    • 77953316514 scopus 로고    scopus 로고
    • Mechanism and evolution of cytosolic Hedgehog signal transduction
    • Wilson CW, Chuang PT (2010) Mechanism and evolution of cytosolic Hedgehog signal transduction. Development 137: 2079-2094.
    • (2010) Development , vol.137 , pp. 2079-2094
    • Wilson, C.W.1    Chuang, P.T.2
  • 3
    • 0242581681 scopus 로고    scopus 로고
    • Hedgehog signalling in the mouse requires intraflagellar transport proteins
    • Huangfu D, Liu A, Rakeman AS, Murcia NS, Niswander L, et al. (2003) Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426: 83-87.
    • (2003) Nature , vol.426 , pp. 83-87
    • Huangfu, D.1    Liu, A.2    Rakeman, A.S.3    Murcia, N.S.4    Niswander, L.5
  • 4
    • 40749144679 scopus 로고    scopus 로고
    • Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
    • Haycraft CJ, Banizs B, Aydin-Son Y, Zhang Q, Michaud EJ, et al. (2005) Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet 1: e53.
    • (2005) PLoS Genet , vol.1
    • Haycraft, C.J.1    Banizs, B.2    Aydin-Son, Y.3    Zhang, Q.4    Michaud, E.J.5
  • 5
    • 23144466931 scopus 로고    scopus 로고
    • Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
    • Liu A, Wang B, Niswander LA (2005) Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 132: 3103-3111.
    • (2005) Development , vol.132 , pp. 3103-3111
    • Liu, A.1    Wang, B.2    Niswander, L.A.3
  • 6
    • 23844485210 scopus 로고    scopus 로고
    • Cilia and Hedgehog responsiveness in the mouse
    • Huangfu D, Anderson KV (2005) Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A 102: 11325-11330.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11325-11330
    • Huangfu, D.1    Anderson, K.V.2
  • 7
    • 27744484694 scopus 로고    scopus 로고
    • Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
    • May SR, Ashique AM, Karlen M, Wang B, Shen Y, et al. (2005) Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev Biol 287: 378-389.
    • (2005) Dev Biol , vol.287 , pp. 378-389
    • May, S.R.1    Ashique, A.M.2    Karlen, M.3    Wang, B.4    Shen, Y.5
  • 8
    • 67349198593 scopus 로고    scopus 로고
    • Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia
    • Jia J, Kolterud A, Zeng H, Hoover A, Teglund S, et al. (2009) Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia. Dev Biol 330: 452-460.
    • (2009) Dev Biol , vol.330 , pp. 452-460
    • Jia, J.1    Kolterud, A.2    Zeng, H.3    Hoover, A.4    Teglund, S.5
  • 9
    • 69249245332 scopus 로고    scopus 로고
    • Ciliumindependent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
    • Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, et al. (2009) Ciliumindependent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev 23: 1910-1928.
    • (2009) Genes Dev , vol.23 , pp. 1910-1928
    • Chen, M.H.1    Wilson, C.W.2    Li, Y.J.3    Law, K.K.4    Lu, C.S.5
  • 11
    • 62549159642 scopus 로고    scopus 로고
    • Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process
    • Rohatgi R, Milenkovic L, Corcoran RB, Scott MP (2009) Hedgehog signal transduction by Smoothened: pharmacologic evidence for a 2-step activation process. Proc Natl Acad Sci U S A 106: 3196-3201.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3196-3201
    • Rohatgi, R.1    Milenkovic, L.2    Corcoran, R.B.3    Scott, M.P.4
  • 12
    • 62449174504 scopus 로고    scopus 로고
    • Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation
    • Wang Y, Zhou Z, Walsh CT, McMahon AP (2009) Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation. Proc Natl Acad Sci U S A 106: 2623-2628.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2623-2628
    • Wang, Y.1    Zhou, Z.2    Walsh, C.T.3    McMahon, A.P.4
  • 13
    • 65249123996 scopus 로고    scopus 로고
    • Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium
    • Wilson CW, Chen MH, Chuang PT (2009) Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium. PLoS One 4: e5182.
    • (2009) PLoS One , vol.4
    • Wilson, C.W.1    Chen, M.H.2    Chuang, P.T.3
  • 14
    • 34547110771 scopus 로고    scopus 로고
    • Patched1 regulates hedgehog signaling at the primary cilium
    • Rohatgi R, Milenkovic L, Scott MP (2007) Patched1 regulates hedgehog signaling at the primary cilium. Science 317: 372-376.
    • (2007) Science , vol.317 , pp. 372-376
    • Rohatgi, R.1    Milenkovic, L.2    Scott, M.P.3
  • 15
    • 76049114315 scopus 로고    scopus 로고
    • Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus
    • Kim J, Kato M, Beachy PA (2009) Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus. Proc Natl Acad Sci U S A 106: 21666-21671.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 21666-21671
    • Kim, J.1    Kato, M.2    Beachy, P.A.3
  • 16
    • 77950671813 scopus 로고    scopus 로고
    • Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation
    • Wen X, Lai CK, Evangelista M, Hongo JA, de Sauvage FJ, et al. (2010) Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation. Mol Cell Biol 30: 1910-1922.
    • (2010) Mol Cell Biol , vol.30 , pp. 1910-1922
    • Wen, X.1    Lai, C.K.2    Evangelista, M.3    Hongo, J.A.4    de Sauvage, F.J.5
  • 17
    • 31744451535 scopus 로고    scopus 로고
    • Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
    • Svard J, Heby-Henricson K, Persson-Lek M, Rozell B, Lauth M, et al. (2006) Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. Dev Cell 10: 187-197.
    • (2006) Dev Cell , vol.10 , pp. 187-197
    • Svard, J.1    Heby-Henricson, K.2    Persson-Lek, M.3    Rozell, B.4    Lauth, M.5
  • 18
    • 27644584608 scopus 로고    scopus 로고
    • Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused
    • Cooper AF, Yu KP, Brueckner M, Brailey LL, Johnson L, et al. (2005) Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused. Development 132: 4407-4417.
    • (2005) Development , vol.132 , pp. 4407-4417
    • Cooper, A.F.1    Yu, K.P.2    Brueckner, M.3    Brailey, L.L.4    Johnson, L.5
  • 19
    • 0026761497 scopus 로고
    • Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster
    • Preat T (1992) Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster. Genetics 132: 725-736.
    • (1992) Genetics , vol.132 , pp. 725-736
    • Preat, T.1
  • 20
    • 0033533714 scopus 로고    scopus 로고
    • Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1
    • Ding Q, Fukami S, Meng X, Nishizaki Y, Zhang X, et al. (1999) Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr Biol 9: 1119-1122.
    • (1999) Curr Biol , vol.9 , pp. 1119-1122
    • Ding, Q.1    Fukami, S.2    Meng, X.3    Nishizaki, Y.4    Zhang, X.5
  • 21
    • 0033194243 scopus 로고    scopus 로고
    • Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-Nat
    • Kogerman P, Grimm T, Kogerman L, Krause D, Unden AB, et al. (1999) Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-Nat Cell Biol 1: 312-319.
    • (1999) Cell Biol , vol.1 , pp. 312-319
    • Kogerman, P.1    Grimm, T.2    Kogerman, L.3    Krause, D.4    Unden, A.B.5
  • 22
    • 0033566844 scopus 로고    scopus 로고
    • Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators
    • Pearse RV, 2nd, Collier LS, Scott MP, Tabin CJ (1999) Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators. Dev Biol 212: 323-336.
    • (1999) Dev Biol , vol.212 , pp. 323-336
    • Pearse II, R.V.1    Collier, L.S.2    Scott, M.P.3    Tabin, C.J.4
  • 23
    • 0033491071 scopus 로고    scopus 로고
    • Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
    • Stone DM, Murone M, Luoh S, Ye W, Armanini MP, et al. (1999) Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J Cell Sci 112(Pt 23): 4437-4448.
    • (1999) J Cell Sci , vol.112 , Issue.PT 23 , pp. 4437-4448
    • Stone, D.M.1    Murone, M.2    Luoh, S.3    Ye, W.4    Armanini, M.P.5
  • 24
    • 0033789068 scopus 로고    scopus 로고
    • Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus
    • Methot N, Basler K (2000) Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. Development 127: 4001-4010.
    • (2000) Development , vol.127 , pp. 4001-4010
    • Methot, N.1    Basler, K.2
  • 25
    • 0033781026 scopus 로고    scopus 로고
    • Gli regulation by the opposing activities of fused and suppressor of fused
    • Murone M, Luoh SM, Stone D, Li W, Gurney A, et al. (2000) Gli regulation by the opposing activities of fused and suppressor of fused. Nat Cell Biol 2: 310-312.
    • (2000) Nat Cell Biol , vol.2 , pp. 310-312
    • Murone, M.1    Luoh, S.M.2    Stone, D.3    Li, W.4    Gurney, A.5
  • 26
    • 33646235390 scopus 로고    scopus 로고
    • Regulation of Ci and Su(fu) nuclear import in Drosophila
    • Sisson BE, Ziegenhorn SL, Holmgren RA (2006) Regulation of Ci and Su(fu) nuclear import in Drosophila. Dev Biol 294: 258-270.
    • (2006) Dev Biol , vol.294 , pp. 258-270
    • Sisson, B.E.1    Ziegenhorn, S.L.2    Holmgren, R.A.3
  • 27
    • 0037117611 scopus 로고    scopus 로고
    • Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex
    • Cheng SY, Bishop JM (2002) Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex. Proc Natl Acad Sci U S A 99: 5442-5447.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 5442-5447
    • Cheng, S.Y.1    Bishop, J.M.2
  • 28
    • 1642370648 scopus 로고    scopus 로고
    • The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins
    • Paces-Fessy M, Boucher D, Petit E, Paute-Briand S, Blanchet-Tournier MF (2004) The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins. Biochem J 378: 353-362.
    • (2004) Biochem J , vol.378 , pp. 353-362
    • Paces-Fessy, M.1    Boucher, D.2    Petit, E.3    Paute-Briand, S.4    Blanchet-Tournier, M.F.5
  • 29
    • 77950463564 scopus 로고    scopus 로고
    • The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
    • Humke EW, Dorn KV, Milenkovic L, Scott MP, Rohatgi R (2010) The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins. Genes Dev 24: 670-682.
    • (2010) Genes Dev , vol.24 , pp. 670-682
    • Humke, E.W.1    Dorn, K.V.2    Milenkovic, L.3    Scott, M.P.4    Rohatgi, R.5
  • 30
    • 0036801765 scopus 로고    scopus 로고
    • Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
    • Bai CB, Auerbach W, Lee JS, Stephen D, Joyner AL (2002) Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development 129: 4753-4761.
    • (2002) Development , vol.129 , pp. 4753-4761
    • Bai, C.B.1    Auerbach, W.2    Lee, J.S.3    Stephen, D.4    Joyner, A.L.5
  • 31
    • 0036134643 scopus 로고    scopus 로고
    • High-resolution mapping of the Gli3 mutation extra-toes reveals a 51.5-kb deletion
    • Maynard TM, Jain MD, Balmer CW, LaMantia AS (2002) High-resolution mapping of the Gli3 mutation extra-toes reveals a 51.5-kb deletion. Mamm Genome 13: 58-61.
    • (2002) Mamm Genome , vol.13 , pp. 58-61
    • Maynard, T.M.1    Jain, M.D.2    Balmer, C.W.3    La Mantia, A.S.4
  • 32
    • 60849116473 scopus 로고    scopus 로고
    • C2cd3 is required for cilia formation and Hedgehog signaling in mouse
    • Hoover AN, Wynkoop A, Zeng H, Jia J, Niswander LA, et al. (2008) C2cd3 is required for cilia formation and Hedgehog signaling in mouse. Development 135: 4049-4058.
    • (2008) Development , vol.135 , pp. 4049-4058
    • Hoover, A.N.1    Wynkoop, A.2    Zeng, H.3    Jia, J.4    Niswander, L.A.5
  • 33
    • 0032848136 scopus 로고    scopus 로고
    • Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling
    • Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H (1999) Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development 126: 3915-3924.
    • (1999) Development , vol.126 , pp. 3915-3924
    • Sasaki, H.1    Nishizaki, Y.2    Hui, C.3    Nakafuku, M.4    Kondoh, H.5
  • 34
    • 0141480791 scopus 로고    scopus 로고
    • Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm
    • Han YG, Kwok BH, Kernan MJ (2003) Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm. Curr Biol 13: 1679-1686.
    • (2003) Curr Biol , vol.13 , pp. 1679-1686
    • Han, Y.G.1    Kwok, B.H.2    Kernan, M.J.3
  • 35
    • 0141592294 scopus 로고    scopus 로고
    • Drosophila KAP interacts with the kinesin II motor subunit KLP64D to assemble chordotonal sensory cilia, but not sperm tails
    • Sarpal R, Todi SV, Sivan-Loukianova E, Shirolikar S, Subramanian N, et al. (2003) Drosophila KAP interacts with the kinesin II motor subunit KLP64D to assemble chordotonal sensory cilia, but not sperm tails. Curr Biol 13: 1687-1696.
    • (2003) Curr Biol , vol.13 , pp. 1687-1696
    • Sarpal, R.1    Todi, S.V.2    Sivan-Loukianova, E.3    Shirolikar, S.4    Subramanian, N.5
  • 36
    • 71549119821 scopus 로고    scopus 로고
    • Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia
    • Rink JC, Gurley KA, Elliott SA, Sanchez Alvarado A (2009) Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia. Science 326: 1406-1410.
    • (2009) Science , vol.326 , pp. 1406-1410
    • Rink, J.C.1    Gurley, K.A.2    Elliott, S.A.3    Sanchez Alvarado, A.4
  • 37
    • 38449099388 scopus 로고    scopus 로고
    • Homologs of the Hh signalling network in C. elegans
    • Burglin TR, Kuwabara PE (2006) Homologs of the Hh signalling network in C. elegans. WormBook. pp 1-14.
    • (2006) WormBook , pp. 1-14
    • Burglin, T.R.1    Kuwabara, P.E.2
  • 38
    • 0034681266 scopus 로고    scopus 로고
    • Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
    • Wang B, Fallon JF, Beachy PA (2000) Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100: 423-434.
    • (2000) Cell , vol.100 , pp. 423-434
    • Wang, B.1    Fallon, J.F.2    Beachy, P.A.3
  • 39
    • 33646270662 scopus 로고    scopus 로고
    • Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
    • Pan Y, Bai CB, Joyner AL, Wang B (2006) Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation. Mol Cell Biol 26: 3365-3377.
    • (2006) Mol Cell Biol , vol.26 , pp. 3365-3377
    • Pan, Y.1    Bai, C.B.2    Joyner, A.L.3    Wang, B.4
  • 40
    • 52449134915 scopus 로고    scopus 로고
    • Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines
    • Lipinski RJ, Bijlsma MF, Gipp JJ, Podhaizer DJ, Bushman W (2008) Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines. BMC Cell Biol 9: 49.
    • (2008) BMC Cell Biol , vol.9 , pp. 49
    • Lipinski, R.J.1    Bijlsma, M.F.2    Gipp, J.J.3    Podhaizer, D.J.4    Bushman, W.5
  • 41
    • 63049116544 scopus 로고    scopus 로고
    • The vertebrate primary cilium in development, homeostasis, and disease
    • Gerdes JM, Davis EE, Katsanis N (2009) The vertebrate primary cilium in development, homeostasis, and disease. Cell 137: 32-45.
    • (2009) Cell , vol.137 , pp. 32-45
    • Gerdes, J.M.1    Davis, E.E.2    Katsanis, N.3
  • 42
    • 0031019090 scopus 로고    scopus 로고
    • GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome
    • Kang S, Graham JM, Jr., Olney AH, Biesecker LG (1997) GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome. Nat Genet 15: 266-268.
    • (1997) Nat Genet , vol.15 , pp. 266-268
    • Kang, S.1    Graham Jr., J.M.2    Olney, A.H.3    Biesecker, L.G.4
  • 43
    • 0036566575 scopus 로고    scopus 로고
    • Pallister-Hall syndrome phenotype in mice mutant for Gli3
    • Bose J, Grotewold L, Ruther U (2002) Pallister-Hall syndrome phenotype in mice mutant for Gli3. Hum Mol Genet 11: 1129-1135.
    • (2002) Hum Mol Genet , vol.11 , pp. 1129-1135
    • Bose, J.1    Grotewold, L.2    Ruther, U.3
  • 44
    • 34247569471 scopus 로고    scopus 로고
    • The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning
    • Wang C, Ruther U, Wang B (2007) The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning. Dev Biol 305: 460-469.
    • (2007) Dev Biol , vol.305 , pp. 460-469
    • Wang, C.1    Ruther, U.2    Wang, B.3
  • 45
    • 68149178664 scopus 로고    scopus 로고
    • The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development
    • Endoh-Yamagami S, Evangelista M, Wilson D, Wen X, Theunissen JW, et al. (2009) The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol 19: 1320-1326.
    • (2009) Curr Biol , vol.19 , pp. 1320-1326
    • Endoh-Yamagami, S.1    Evangelista, M.2    Wilson, D.3    Wen, X.4    Theunissen, J.W.5
  • 46
    • 0033581926 scopus 로고    scopus 로고
    • Distinct and regulated activities of human Gli proteins in Drosophila
    • von Mering C, Basler K (1999) Distinct and regulated activities of human Gli proteins in Drosophila. Curr Biol 9: 1319-1322.
    • (1999) Curr Biol , vol.9 , pp. 1319-1322
    • von Mering, C.1    Basler, K.2
  • 47
    • 0033761448 scopus 로고    scopus 로고
    • Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities
    • Aza-Blanc P, Lin HY, Ruiz i Altaba A, Kornberg TB (2000) Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. Development 127: 4293-4301.
    • (2000) Development , vol.127 , pp. 4293-4301
    • Aza-Blanc, P.1    Lin, H.Y.2    Ruiz i Altaba, A.3    Kornberg, T.B.4
  • 48
    • 77958508124 scopus 로고    scopus 로고
    • A mechanism for vertebrate Hedgehog signaling: Recruitment to cilia and dissociation of SuFu-Gli protein complexes
    • Tukachinsky H, Lopez LV, Salic A (2010) A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes. J Cell Biol 191: 415-428.
    • (2010) J Cell Biol , vol.191 , pp. 415-428
    • Tukachinsky, H.1    Lopez, L.V.2    Salic, A.3
  • 49
    • 0038813753 scopus 로고    scopus 로고
    • Characterization of the physical interaction of Gli proteins with SUFU proteins
    • Dunaeva M, Michelson P, Kogerman P, Toftgard R (2003) Characterization of the physical interaction of Gli proteins with SUFU proteins. J Biol Chem 278: 5116-5122.
    • (2003) J Biol Chem , vol.278 , pp. 5116-5122
    • Dunaeva, M.1    Michelson, P.2    Kogerman, P.3    Toftgard, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.