High-resolution mapping of the Gli3 mutation extra-toesJ reveals a 51.5-kb deletion

Mammalian Genome

Volumn 13, Issue 1, 2002, Pages 58-61

  Maynard, Thomas M ^a   Jain, Michael D ^a   Balmer, Curtis W ^a   LaMantia, Anthony Samuel ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ANIMAL MODEL; ARTICLE; CHROMOSOME DELETION; EMBRYO; GENE MAPPING; GENOME; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYDACTYLY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNDACTYLY; TOE MALFORMATION;

ANIMALS; BASE SEQUENCE; CHROMOSOME DELETION; CONTIG MAPPING; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; FORELIMB; HINDLIMB; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY; TOES; TRANSCRIPTION FACTORS; XENOPUS PROTEINS;

ANIMALIA;

EID: 0036134643     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-001-2115-X     Document Type: Article

References (16)

1. Basic local alignment search tool
2. The XtJ allele generates a Gli3 fusion transcript
3. Extra-toes (Xt) homozygous mutant mice demonstrate a role for the Gli-3 gene in the development of the forebrain
4. Evidence for the involvement of the Gli gene family in embryonic mouse lung development
5. A mouse model of greig cephalopolysyndactyly syndrome: The extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
6. Extra-toes: A new mutant gene causing multiple abnormalities in the mouse
7. Gene structure and allelic expression assay of the human GL13 gene
8. Forebrain induction, retinoic acid, and vulnerability to schizophrenia: Insights from molecular and genetic analysis in developing mice
9. Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development
10. Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt)
11. New allele of extra toes spotting
12. Cloning and sequence analysis of the murine Gli3 cDNA
13. Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT)
14. Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS) and the mouse mutant extra toes (Xt)
15. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
16. Greig cephalopolysyndactyly syndrome: A possible mouse homologue (Xt-extra toes)