Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia

Science

Volumn 326, Issue 5958, 2009, Pages 1406-1410

  Rink, Jochen C ^a   Gurley, Kyle A ^a   Elliott, Sarah A ^a   Alvarado, Alejandro Sánchez ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

FLATWORM; HOMEOSTASIS; MOLECULAR ECOLOGY; PROTEIN; REGENERATION; RNA; SMALL MAMMAL; SPECIES DIVERSITY;

ARTICLE; EUKARYOTIC FLAGELLUM; EVOLUTION; LIZARD; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TURBELLARIA;

ANIMALS; BETA CATENIN; BODY PATTERNING; CILIA; EVOLUTION; GENES, HELMINTH; HEDGEHOG PROTEINS; HELMINTH PROTEINS; MOLECULAR SEQUENCE DATA; PLANARIANS; REGENERATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WNT PROTEINS;

ANIMALIA; ERINACEIDAE; IGUANA; MAMMALIA; METAZOA; PLANARIA; TURBELLARIA;

EID: 71549119821     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1178712     Document Type: Article

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39. We thank the Sánchez laboratory for helpful comments and C. Adler for sharing data on iguana. Work supported by NIH National Institute of General Medical Sciences grants RO-1 GM57260 to A.S.A. and F32GM082016 to K.A.G. J.C.R. was funded by the European Molecular Biology Association. A.S.A. is a Howard Hughes Medical Institute investigator. All sequences associated with this study have been deposited in GenBank and have accession numbers GQ337474 to GQ337490.