-
1
-
-
67349253085
-
Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: Role of Abeta in pathogenesis
-
Sultana R., Perluigi M., Butterfield D. A., Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis Acta Neuropathologica 2009 118 1 131 150
-
(2009)
Acta Neuropathologica
, vol.118
, Issue.1
, pp. 131-150
-
-
Sultana, R.1
Perluigi, M.2
Butterfield, D.A.3
-
2
-
-
67649678412
-
Oxidative stress in diabetes and Alzheimer's disease
-
Reddy V. P., Zhu X., Perry G., Smith M. A., Oxidative stress in diabetes and Alzheimer's disease Journal of Alzheimer's Disease 2009 16 4 763 774
-
(2009)
Journal of Alzheimer's Disease
, vol.16
, Issue.4
, pp. 763-774
-
-
Reddy, V.P.1
Zhu, X.2
Perry, G.3
Smith, M.A.4
-
3
-
-
77951689435
-
Biomarkers of oxidative damage and inflammation in Alzheimers disease
-
Galasko D., Montine T. J., Biomarkers of oxidative damage and inflammation in Alzheimers disease Biomarkers in Medicine 2010 4 1 27 36
-
(2010)
Biomarkers in Medicine
, vol.4
, Issue.1
, pp. 27-36
-
-
Galasko, D.1
Montine, T.J.2
-
4
-
-
77951683939
-
Biomarkers in Alzheimers disease: Past, present and future
-
Gustaw-Rothenberg K., Lerner A., Bonda D. J., Lee H.-G., Zhu X., Perry G., Smith M. A., Biomarkers in Alzheimers disease: past, present and future Biomarkers in Medicine 2010 4 1 15 26
-
(2010)
Biomarkers in Medicine
, vol.4
, Issue.1
, pp. 15-26
-
-
Gustaw-Rothenberg, K.1
Lerner, A.2
Bonda, D.J.3
Lee, H.-G.4
Zhu, X.5
Perry, G.6
Smith, M.A.7
-
6
-
-
39749196738
-
Why is the amyloid beta peptide of Alzheimer's disease neurotoxic?
-
Rauk A., Why is the amyloid beta peptide of Alzheimer's disease neurotoxic? Dalton Transactions 2008 10 1273 1282
-
(2008)
Dalton Transactions
, Issue.10
, pp. 1273-1282
-
-
Rauk, A.1
-
7
-
-
70350153272
-
The chemistry of Alzheimer's disease
-
Rauk A., The chemistry of Alzheimer's disease Chemical Society Reviews 2009 38 9 2698 2715
-
(2009)
Chemical Society Reviews
, vol.38
, Issue.9
, pp. 2698-2715
-
-
Rauk, A.1
-
8
-
-
12144282992
-
Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's A peptides
-
Huang X., Atwood C. S., Moir R. D., Hartshorn M. A., Tanzi R. E., Bush A. I., Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's A peptides Journal of Biological Inorganic Chemistry 2004 9 8 954 960
-
(2004)
Journal of Biological Inorganic Chemistry
, vol.9
, Issue.8
, pp. 954-960
-
-
Huang, X.1
Atwood, C.S.2
Moir, R.D.3
Hartshorn, M.A.4
Tanzi, R.E.5
Bush, A.I.6
-
9
-
-
0035873812
-
-synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro
-
Turnbull S., Tabner B. J., El-Agnaf O. M. A., Moore S., Davies Y., Allsop D., -synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro Free Radical Biology and Medicine 2001 30 10 1163 1170
-
(2001)
Free Radical Biology and Medicine
, vol.30
, Issue.10
, pp. 1163-1170
-
-
Turnbull, S.1
Tabner, B.J.2
El-Agnaf, O.M.A.3
Moore, S.4
Davies, Y.5
Allsop, D.6
-
10
-
-
0028233494
-
Hydrogen peroxide mediates amyloid protein toxicity
-
Behl C., Davis J. B., Lesley R., Schubert D., Hydrogen peroxide mediates amyloid protein toxicity Cell 1994 77 6 817 827
-
(1994)
Cell
, vol.77
, Issue.6
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
11
-
-
18344414746
-
The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
DOI 10.1021/bi990438f
-
Huang X., Atwood C. S., Hartshorn M. A., Multhaup G., Goldstein L. E., Scarpa R. C., Cuajungco M. P., Gray D. N., Lim J., Moir R. D., Tanzi R. E., Bush A. I., The A peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction Biochemistry 1999 38 24 7609 7616 (Pubitemid 29289332)
-
(1999)
Biochemistry
, vol.38
, Issue.24
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.C.6
Cuajungco, M.P.7
Gray, D.N.8
Lim, J.9
Moir, R.D.10
Tanzi, R.E.11
Bush, A.I.12
-
12
-
-
0033601338
-
Cu(II) potentiation of Alzheimer a neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction
-
Huang X., Cuajungco M. P., Atwood C. S., Hartshorn M. A., Tyndall J. D. A., Hanson G. R., Stokes K. C., Leopold M., Multhaup G., Goldstein L. E., Scarpa R. C., Saunders A. J., Lim J., Moir R. D., Glabe C., Bowden E. F., Masters C. L., Fairlie D. P., Tanzi R. E., Bush A. I., Cu(II) potentiation of Alzheimer a neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction Journal of Biological Chemistry 1999 274 52 37111 37116
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.52
, pp. 37111-37116
-
-
Huang, X.1
Cuajungco, M.P.2
Atwood, C.S.3
Hartshorn, M.A.4
Tyndall, J.D.A.5
Hanson, G.R.6
Stokes, K.C.7
Leopold, M.8
Multhaup, G.9
Goldstein, L.E.10
Scarpa, R.C.11
Saunders, A.J.12
Lim, J.13
Moir, R.D.14
Glabe, C.15
Bowden, E.F.16
Masters, C.L.17
Fairlie, D.P.18
Tanzi, R.E.19
Bush, A.I.20
more..
-
13
-
-
0032507975
-
Copper, iron and zinc in Alzheimer's disease senile plaques
-
Lovell M. A., Robertson J. D., Teesdale W. J., Campbell J. L., Markesbery W. R., Copper, iron and zinc in Alzheimer's disease senile plaques Journal of the Neurological Sciences 1998 158 1 47 52
-
(1998)
Journal of the Neurological Sciences
, vol.158
, Issue.1
, pp. 47-52
-
-
Lovell, M.A.1
Robertson, J.D.2
Teesdale, W.J.3
Campbell, J.L.4
Markesbery, W.R.5
-
14
-
-
0030885482
-
Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
-
Smith M. A., Harris P. L. R., Sayre L. M., Perry G., Iron accumulation in Alzheimer disease is a source of redox-generated free radicals Proceedings of the National Academy of Sciences of the United States of America 1997 94 18 9866 9868
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.18
, pp. 9866-9868
-
-
Smith, M.A.1
Harris, P.L.R.2
Sayre, L.M.3
Perry, G.4
-
15
-
-
34547914869
-
Redox reactions of copper complexes formed with different -amyloid peptides and their neuropathalogical relevance
-
Jiang D., Men L., Wang J., Zhang Y., Chickenyen S., Wang Y., Zhou F., Redox reactions of copper complexes formed with different -amyloid peptides and their neuropathalogical relevance Biochemistry 2007 46 32 9270 9282
-
(2007)
Biochemistry
, vol.46
, Issue.32
, pp. 9270-9282
-
-
Jiang, D.1
Men, L.2
Wang, J.3
Zhang, Y.4
Chickenyen, S.5
Wang, Y.6
Zhou, F.7
-
16
-
-
0036591852
-
Formation of hydrogen peroxide and hydroxyl radicals from A and -synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease
-
Tabner B. J., Turnbull S., El-Agnaf O. M. A., Allsop D., Formation of hydrogen peroxide and hydroxyl radicals from A and -synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease Free Radical Biology and Medicine 2002 32 11 1076 1083
-
(2002)
Free Radical Biology and Medicine
, vol.32
, Issue.11
, pp. 1076-1083
-
-
Tabner, B.J.1
Turnbull, S.2
El-Agnaf, O.M.A.3
Allsop, D.4
-
17
-
-
0037174856
-
Metalloenzyme-like activity of Alzheimer's disease -amyloid: Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H 2 O 2
-
Opazo C., Huang X., Cherny R. A., Moir R. D., Roher A. E., White A. R., Cappai R., Masters C. L., Tanzi R. E., Inestrosa N. C., Bush A. I., Metalloenzyme-like activity of Alzheimer's disease -amyloid: Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H 2 O 2 Journal of Biological Chemistry 2002 277 43 40302 40308
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.43
, pp. 40302-40308
-
-
Opazo, C.1
Huang, X.2
Cherny, R.A.3
Moir, R.D.4
Roher, A.E.5
White, A.R.6
Cappai, R.7
Masters, C.L.8
Tanzi, R.E.9
Inestrosa, N.C.10
Bush, A.I.11
-
18
-
-
9444284334
-
Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease -amyloid
-
Barnham K. J., Haeffner F., Ciccotosto G. D., Curtain C. C., Tew D., Mavros C., Beyreuther K., Carrington D., Masters C. L., Cherny R. A., Cappai R., Bush A. I., Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease -amyloid FASEB Journal 2004 18 12 1427 1429
-
(2004)
FASEB Journal
, vol.18
, Issue.12
, pp. 1427-1429
-
-
Barnham, K.J.1
Haeffner, F.2
Ciccotosto, G.D.3
Curtain, C.C.4
Tew, D.5
Mavros, C.6
Beyreuther, K.7
Carrington, D.8
Masters, C.L.9
Cherny, R.A.10
Cappai, R.11
Bush, A.I.12
-
19
-
-
14844304305
-
Oxidation of cholesterol by amyloid precursor protein and -amyloid peptide
-
Nelson T. J., Alkon D. L., Oxidation of cholesterol by amyloid precursor protein and -amyloid peptide Journal of Biological Chemistry 2005 280 8 7377 7387
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.8
, pp. 7377-7387
-
-
Nelson, T.J.1
Alkon, D.L.2
-
20
-
-
55249115550
-
Amyloid -Cu2+ complexes in both monomeric and fibrillar forms do not generate H 2 O 2 catalytically but quench hydroxyl radicals
-
Nadal R. C., Rigby S. E. J., Viles J. H., Amyloid -Cu2+ complexes in both monomeric and fibrillar forms do not generate H 2 O 2 catalytically but quench hydroxyl radicals Biochemistry 2008 47 44 11653 11664
-
(2008)
Biochemistry
, vol.47
, Issue.44
, pp. 11653-11664
-
-
Nadal, R.C.1
Rigby, S.E.J.2
Viles, J.H.3
-
21
-
-
77950189704
-
Copper enhances amyloid- peptide neurotoxicity and non -aggregation: A series of experiments conducted upon copper-bound and copper-free amyloid- peptide
-
Dai X., Sun Y., Gao Z., Jiang Z., Copper enhances amyloid- peptide neurotoxicity and non -aggregation: a series of experiments conducted upon copper-bound and copper-free amyloid- peptide Journal of Molecular Neuroscience 2010 41 1 66 73
-
(2010)
Journal of Molecular Neuroscience
, vol.41
, Issue.1
, pp. 66-73
-
-
Dai, X.1
Sun, Y.2
Gao, Z.3
Jiang, Z.4
-
22
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A., Perry G., Aliev G., Hirai K., Takeda A., Balraj E. K., Jones P. K., Ghanbari H., Wataya T., Shimohama S., Chiba S., Atwood C. S., Petersen R. B., Smith M. A., Oxidative damage is the earliest event in Alzheimer disease Journal of Neuropathology and Experimental Neurology 2001 60 8 759 767
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.8
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
23
-
-
27644446857
-
Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment
-
Markesbery W. R., Kryscio R. J., Lovell M. A., Morrow J. D., Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment Annals of Neurology 2005 58 5 730 735
-
(2005)
Annals of Neurology
, vol.58
, Issue.5
, pp. 730-735
-
-
Markesbery, W.R.1
Kryscio, R.J.2
Lovell, M.A.3
Morrow, J.D.4
-
24
-
-
77954835300
-
High-molecular-weight -amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients
-
Fukumoto H., Tokuda T., Kasai T., Ishigami N., Hidaka H., Kondo M., Allsop D., Nakagawa M., High-molecular-weight -amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients FASEB Journal 2010 24 8 2716 2726
-
(2010)
FASEB Journal
, vol.24
, Issue.8
, pp. 2716-2726
-
-
Fukumoto, H.1
Tokuda, T.2
Kasai, T.3
Ishigami, N.4
Hidaka, H.5
Kondo, M.6
Allsop, D.7
Nakagawa, M.8
-
25
-
-
27744542593
-
Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia
-
Tabner B. J., El-Agnaf O. M. A., Turnbull S., German M. J., Paleologou K. E., Hayashi Y., Cooper L. J., Fullwood N. J., Allsop D., Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia Journal of Biological Chemistry 2005 280 43 35789 35792
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.43
, pp. 35789-35792
-
-
Tabner, B.J.1
El-Agnaf, O.M.A.2
Turnbull, S.3
German, M.J.4
Paleologou, K.E.5
Hayashi, Y.6
Cooper, L.J.7
Fullwood, N.J.8
Allsop, D.9
-
26
-
-
42449090677
-
Cu(II) binding to monomeric, oligomeric, and fibrillar forms of the Alzheimer's disease amyloid- peptide
-
Karr J. W., Szalai V. A., Cu(II) binding to monomeric, oligomeric, and fibrillar forms of the Alzheimer's disease amyloid- peptide Biochemistry 2008 47 17 5006 5016
-
(2008)
Biochemistry
, vol.47
, Issue.17
, pp. 5006-5016
-
-
Karr, J.W.1
Szalai, V.A.2
-
27
-
-
8744220663
-
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases
-
Kayed R., Sokolov Y., Edmonds B., McIntire T. M., Milton S. C., Hall J. E., Glabe C. G., Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases Journal of Biological Chemistry 2004 279 45 46363 46366
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.45
, pp. 46363-46366
-
-
Kayed, R.1
Sokolov, Y.2
Edmonds, B.3
McIntire, T.M.4
Milton, S.C.5
Hall, J.E.6
Glabe, C.G.7
-
28
-
-
20444496481
-
Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
-
Demuro A., Mina E., Kayed R., Milton S. C., Parker I., Glabe C. G., Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers Journal of Biological Chemistry 2005 280 17 17294 17300
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 17294-17300
-
-
Demuro, A.1
Mina, E.2
Kayed, R.3
Milton, S.C.4
Parker, I.5
Glabe, C.G.6
-
29
-
-
46749100924
-
Therapeutics for Alzheimer's disease based on the metal hypothesis
-
Bush A. I., Tanzi R. E., Therapeutics for Alzheimer's disease based on the metal hypothesis Neurotherapeutics 2008 5 3 421 432
-
(2008)
Neurotherapeutics
, vol.5
, Issue.3
, pp. 421-432
-
-
Bush, A.I.1
Tanzi, R.E.2
-
30
-
-
0037461576
-
Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126
-
DOI 10.1016/S0304-3940(02)01254-5
-
Turnbull S., Tabner B. J., Brown D. R., Allsop D., Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106126 Neuroscience Letters 2003 336 3 159 162 (Pubitemid 36044603)
-
(2003)
Neuroscience Letters
, vol.336
, Issue.3
, pp. 159-162
-
-
Turnbull, S.1
Tabner, B.J.2
Brown, D.R.3
Allsop, D.4
-
31
-
-
0038001458
-
Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231
-
DOI 10.1021/bi030036e
-
Turnbull S., Tabner B. J., Brown D. R., Allsop D., Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121231 Biochemistry 2003 42 25 7675 7681 (Pubitemid 36758932)
-
(2003)
Biochemistry
, vol.42
, Issue.25
, pp. 7675-7681
-
-
Turnbull, S.1
Tabner, B.J.2
Brown, D.R.3
Allsop, D.4
-
32
-
-
59149084113
-
Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease
-
Allsop D., Mayes J., Moore S., Masad A., Tabner B. J., Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease Biochemical Society Transactions 2008 36 6 1293 1298
-
(2008)
Biochemical Society Transactions
, vol.36
, Issue.6
, pp. 1293-1298
-
-
Allsop, D.1
Mayes, J.2
Moore, S.3
Masad, A.4
Tabner, B.J.5
-
33
-
-
0036785151
-
Role of reactive oxygen species in hippocampal long-term potentiation: Contributory or inhibitory?
-
Knapp L. T., Klann E., Role of reactive oxygen species in hippocampal long-term potentiation: contributory or inhibitory? Journal of Neuroscience Research 2002 70 1 1 7
-
(2002)
Journal of Neuroscience Research
, vol.70
, Issue.1
, pp. 1-7
-
-
Knapp, L.T.1
Klann, E.2
-
34
-
-
33846241298
-
Sources and targets of reactive oxygen species in synaptic plasticity and memory
-
Kishida K. T., Klann E., Sources and targets of reactive oxygen species in synaptic plasticity and memory Antioxidants and Redox Signaling 2007 9 2 233 244
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.2
, pp. 233-244
-
-
Kishida, K.T.1
Klann, E.2
-
35
-
-
16644379264
-
Natural oligomers of the amyloid- protein specifically disrupt cognitive function
-
Cleary J. P., Walsh D. M., Hofmeister J. J., Shankar G. M., Kuskowski M. A., Selkoe D. J., Ashe K. H., Natural oligomers of the amyloid- protein specifically disrupt cognitive function Nature Neuroscience 2005 8 1 79 84
-
(2005)
Nature Neuroscience
, vol.8
, Issue.1
, pp. 79-84
-
-
Cleary, J.P.1
Walsh, D.M.2
Hofmeister, J.J.3
Shankar, G.M.4
Kuskowski, M.A.5
Selkoe, D.J.6
Ashe, K.H.7
-
36
-
-
49149124343
-
Amyloid- protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar G. M., Li S., Mehta T. H., Garcia-Munoz A., Shepardson N. E., Smith I., Brett F. M., Farrell M. A., Rowan M. J., Lemere C. A., Regan C. M., Walsh D. M., Sabatini B. L., Selkoe D. J., Amyloid- protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory Nature Medicine 2008 14 8 837 842
-
(2008)
Nature Medicine
, vol.14
, Issue.8
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
|