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Volumn 2010, Issue , 2010, Pages

Coincident in vitro analysis of DNA-PK-dependent and -independent nonhomologous end joining

Author keywords

[No Author keywords available]

Indexed keywords

DNA DEPENDENT PROTEIN KINASE;

EID: 78650623203     PISSN: 20900201     EISSN: 2090021X     Source Type: Journal    
DOI: 10.4061/2010/823917     Document Type: Article
Times cited : (6)

References (75)
  • 1
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • DOI 10.1038/35056049
    • van Gent D. C., Hoeijmakers J. H. J., Kanaar R., Chromosomal stability and the DNA double-stranded break connection. Nature Reviews Genetics 2001 2 3 196 206 2-s2.0-0035289717 10.1038/35056049 (Pubitemid 33674018)
    • (2001) Nature Reviews Genetics , vol.2 , Issue.3 , pp. 196-206
    • Van Gent, D.C.1    Hoeijmakers, J.H.J.2    Kanaar, R.3
  • 2
    • 0030591651 scopus 로고    scopus 로고
    • DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: Bleomycin, neocarzinostatin and other enediynes
    • DOI 10.1016/0027-5107(96)00023-1
    • Povirk L. F., DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes. Mutation Research 1996 355 1-2 71 89 2-s2.0-0030591651 10.1016/0027-5107(96)00023-1 (Pubitemid 26275505)
    • (1996) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , vol.355 , Issue.1-2 , pp. 71-89
    • Povirk, L.F.1
  • 3
    • 38049125555 scopus 로고    scopus 로고
    • The endless tale of non-homologous end-joining
    • 2-s2.0-38049125555 10.1038/cr.2008.3
    • Weterings E., Chen D. J., The endless tale of non-homologous end-joining. Cell Research 2008 18 1 114 124 2-s2.0-38049125555 10.1038/cr.2008.3
    • (2008) Cell Research , vol.18 , Issue.1 , pp. 114-124
    • Weterings, E.1    Chen, D.J.2
  • 4
    • 0031773760 scopus 로고    scopus 로고
    • Identification of genes involved in repair of DNA double-strand breaks in mammalian cells
    • Jeggo P. A., Identification of genes involved in repair of DNA double-strand breaks in mammalian cells. Radiation Research 1998 150 5 S80 S91 2-s2.0-0031773760 (Pubitemid 28519053)
    • (1998) Radiation Research , vol.150 , Issue.5 SUPPL.
    • Jeggo, P.A.1
  • 6
    • 0037155703 scopus 로고    scopus 로고
    • Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
    • DOI 10.1016/S0092-8674(02)00671-2
    • Ma Y., Pannicke U., Schwarz K., Lieber M. R., Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 2002 108 6 781 794 2-s2.0-0037155703 10.1016/S0092-8674(02)00671-2 (Pubitemid 34327530)
    • (2002) Cell , vol.108 , Issue.6 , pp. 781-794
    • Ma, Y.1    Pannicke, U.2    Schwarz, K.3    Lieber, M.R.4
  • 7
    • 9744241712 scopus 로고    scopus 로고
    • A biochemically defined system for mammalian nonhomologous DNA end joining
    • DOI 10.1016/j.molcel.2004.11.017, PII S1097276504007075
    • Ma Y. M., Lu H., Tippin B., Goodman M. F., Shimazaki N., Koiwai O., Hsieh C.-L., Schwarz K., Lieber M. R., A biochemically defined system for mammalian nonhomologous DNA end joining. Molecular Cell 2004 16 5 701 713 2-s2.0-9744241712 10.1016/j.molcel.2004.11.017 (Pubitemid 39586529)
    • (2004) Molecular Cell , vol.16 , Issue.5 , pp. 701-713
    • Ma, Y.1    Lu, H.2    Tippin, B.3    Goodman, M.F.4    Shimazaki, N.5    Koiwai, O.6    Hsieh, C.-L.7    Schwarz, K.8    Lieber, M.R.9
  • 8
    • 0028937877 scopus 로고
    • Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line
    • 2-s2.0-0028937877
    • Lees-Miller S. P., Godbout R., Chan D. W., Weinfeld M., Day R. S. III, Barron G. M., Allalunis-Turner J., Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line. Science 1995 267 5201 1183 1185 2-s2.0-0028937877
    • (1995) Science , vol.267 , Issue.5201 , pp. 1183-1185
    • Lees-Miller, S.P.1    Godbout, R.2    Chan, D.W.3    Weinfeld, M.4    Day III, R.S.5    Barron, G.M.6    Allalunis-Turner, J.7
  • 10
    • 0347510576 scopus 로고    scopus 로고
    • End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4
    • DOI 10.1016/j.dnarep.2003.09.004
    • van Heemst D., Brugmans L., Verkaik N. S., van Gent D. C., End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4. DNA Repair 2004 3 1 43 50 2-s2.0-0347510576 10.1016/j.dnarep.2003.09.004 (Pubitemid 38021994)
    • (2004) DNA Repair , vol.3 , Issue.1 , pp. 43-50
    • Van Heemst, D.1    Brugmans, L.2    Verkaik, N.S.3    Van Gent, D.C.4
  • 11
    • 31044432090 scopus 로고    scopus 로고
    • XLF interacts with the XRCC4-DNA Ligase IV complex to promote DNA nonhomologous end-joining
    • DOI 10.1016/j.cell.2005.12.031, PII S0092867406000031
    • Ahnesorg P., Smith P., Jackson S. P., XLF interacts with the XRCC4-DNA Ligase IV complex to promote DNA nonhomologous end-joining. Cell 2006 124 2 301 313 2-s2.0-31044432090 10.1016/j.cell.2005.12.031 (Pubitemid 43121979)
    • (2006) Cell , vol.124 , Issue.2 , pp. 301-313
    • Ahnesorg, P.1    Smith, P.2    Jackson, S.P.3
  • 13
    • 25444502657 scopus 로고    scopus 로고
    • Artemis links ATM to double strand break rejoining
    • Jeggo P. A., Löbrich M., Artemis links ATM to double strand break rejoining. Cell Cycle 2005 4 3 359 362 2-s2.0-25444502657 (Pubitemid 41359714)
    • (2005) Cell Cycle , vol.4 , Issue.3 , pp. 359-362
    • Jeggo, P.A.1    Lobrich, M.2
  • 14
    • 20644463916 scopus 로고    scopus 로고
    • The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps
    • DOI 10.1016/j.dnarep.2005.04.013, PII S1568786405000972
    • Ma Y., Schwarz K., Lieber M. R., The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps. DNA Repair 2005 4 7 845 851 2-s2.0-20644463916 10.1016/j.dnarep.2005.04.013 (Pubitemid 40835856)
    • (2005) DNA Repair , vol.4 , Issue.7 , pp. 845-851
    • Ma, Y.1    Schwarz, K.2    Lieber, M.R.3
  • 16
    • 67651156039 scopus 로고    scopus 로고
    • Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases λ and μ for nonhomologous end joining in human whole-cell extracts
    • 2-s2.0-67651156039 10.1093/nar/gkp283
    • Akopiants K., Zhou R.-Z., Mohapatra S., Valerie K., Lees-Miller S. P., Lee K.-J., Chen D. J., Revy P., de Villartay J.-P., Povirk L. F., Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases λ and μ for nonhomologous end joining in human whole-cell extracts. Nucleic Acids Research 2009 37 12 4055 4062 2-s2.0-67651156039 10.1093/nar/gkp283
    • (2009) Nucleic Acids Research , vol.37 , Issue.12 , pp. 4055-4062
    • Akopiants, K.1    Zhou, R.-Z.2    Mohapatra, S.3    Valerie, K.4    Lees-Miller, S.P.5    Lee, K.-J.6    Chen, D.J.7    Revy, P.8    De Villartay, J.-P.9    Povirk, L.F.10
  • 19
    • 0036464515 scopus 로고    scopus 로고
    • Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction
    • Huang J. R., Dynan W. S., Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction. Nucleic Acids Research 2002 30 3 667 674 2-s2.0-0036464515 (Pubitemid 34679631)
    • (2002) Nucleic Acids Research , vol.30 , Issue.3 , pp. 667-674
    • Huang, J.1    Dynan, W.S.2
  • 20
    • 0032052815 scopus 로고    scopus 로고
    • Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids
    • DOI 10.1093/nar/26.7.1551
    • Dynan W. S., Yoo S., Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Research 1998 26 7 1551 1559 2-s2.0-0032052815 10.1093/nar/26.7.1551 (Pubitemid 28291787)
    • (1998) Nucleic Acids Research , vol.26 , Issue.7 , pp. 1551-1559
    • Dynan, W.S.1    Yoo, S.2
  • 21
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • DOI 10.1016/0092-8674(93)90057-W
    • Gottlieb T. M., Jackson S. P., The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 1993 72 1 131 142 2-s2.0-0027397867 10.1016/0092-8674(93)90057-W (Pubitemid 23029700)
    • (1993) Cell , vol.72 , Issue.1 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 22
    • 0033572709 scopus 로고    scopus 로고
    • Geometry of a complex formed by double strand break repair proteins at a single DNA end: Recruitment of DNA-PKcs induces inward translocation of Ku protein
    • Yoo S., Dynan W. S., Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein. Nucleic Acids Research 1999 27 24 4679 4686 2-s2.0-0033572709 (Pubitemid 30006656)
    • (1999) Nucleic Acids Research , vol.27 , Issue.24 , pp. 4679-4686
    • Yoo, S.1    Dynan, W.S.2
  • 23
    • 0032938747 scopus 로고    scopus 로고
    • Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining
    • Kurimasa A., Kumano S., Boubnov N. V., Story M. D., Tung C.-S., Peterson S. R., Chen D. J., Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining. Molecular and Cellular Biology 1999 19 5 3877 3884 2-s2.0-0032938747 (Pubitemid 29193847)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.5 , pp. 3877-3884
    • Kurimasa, A.1    Kumano, S.2    Boubnov, N.V.3    Story, M.D.4    Tung, C.-S.5    Peterson, S.R.6    Chen, D.J.7
  • 24
    • 0037124373 scopus 로고    scopus 로고
    • Synapsis of DNA ends by DNA-dependent protein kinase
    • DOI 10.1093/emboj/cdf299
    • DeFazio L. G., Stansel R. M., Griffith J. D., Chu G., Synapsis of DNA ends by DNA-dependent protein kinase. The EMBO Journal 2002 21 12 3192 3200 2-s2.0-0037124373 10.1093/emboj/cdf299 (Pubitemid 34670402)
    • (2002) EMBO Journal , vol.21 , Issue.12 , pp. 3192-3200
    • DeFazio, L.G.1    Stansel, R.M.2    Griffith, J.D.3    Chu, G.4
  • 25
    • 0030743386 scopus 로고    scopus 로고
    • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
    • DOI 10.1038/41358
    • Grawunder U., Wilm M., Wu X., Kulesza P., Wilson T. E., Mann M., Lieber M. R., Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 1997 388 6641 492 495 2-s2.0-0030743386 10.1038/41358 (Pubitemid 27328929)
    • (1997) Nature , vol.388 , Issue.6641 , pp. 492-495
    • Grawunder, U.1    Wilm, M.2    Wu, X.3    Kulesza, P.4    Wilson, T.E.5    Mann, M.6    Lieber, M.R.7
  • 26
    • 0037423743 scopus 로고    scopus 로고
    • Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment
    • DOI 10.1016/S0022-2836(02)01328-1
    • Calsou P., Delteil C., Frit P., Drouet J., Salles B., Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment. Journal of Molecular Biology 2003 326 1 93 103 2-s2.0-0037423743 10.1016/S0022-2836(02)01328-1 (Pubitemid 36279360)
    • (2003) Journal of Molecular Biology , vol.326 , Issue.1 , pp. 93-103
    • Calsou, P.1    Delteil, C.2    Frit, P.3    Drouet, J.4    Salles, B.5
  • 27
    • 0034714199 scopus 로고    scopus 로고
    • Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase
    • 2-s2.0-0034714199 10.1074/jbc.M000491200
    • Chen L., Trujillo K., Sung P., Tomkinson A. E., Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase. Journal of Biological Chemistry 2000 275 34 26196 26205 2-s2.0-0034714199 10.1074/jbc.M000491200
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.34 , pp. 26196-26205
    • Chen, L.1    Trujillo, K.2    Sung, P.3    Tomkinson, A.E.4
  • 28
    • 0037187199 scopus 로고    scopus 로고
    • Defining interactions between DNA-PK and ligase IV/XRCC4
    • DOI 10.1016/S1568-7864(01)00018-0, PII S1568786401000180
    • Hsu H.-L., Yannone S. M., Chen D. J., Defining interactions between DNA-PK and ligase IV/XRCC4. DNA Repair 2002 1 3 225 235 2-s2.0-0037187199 10.1016/S1568-7864(01)00018-0 (Pubitemid 34465484)
    • (2002) DNA Repair , vol.1 , Issue.3 , pp. 225-235
    • Hsu, H.-L.1    Yannone, S.M.2    Chen, D.J.3
  • 29
    • 0033152759 scopus 로고    scopus 로고
    • Competitive and noncompetitive inhibition of the DNA-dependent protein kinase
    • Izzard R. A., Jackson S. P., Smith G. C. M., Competitive and noncompetitive inhibition of the DNA-dependent protein kinase. Cancer Research 1999 59 11 2581 2586 2-s2.0-0033152759 (Pubitemid 29269102)
    • (1999) Cancer Research , vol.59 , Issue.11 , pp. 2581-2586
    • Izzard, R.A.1    Jackson, S.P.2    Smith, G.C.M.3
  • 30
    • 0037159220 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase interacts with DNA to form a protein - DNA complex that is disrupted by phosphorylation
    • DOI 10.1021/bi0263558
    • Merkle D., Douglas P., Moorhead G. B. G., Leonenko Z., Yu Y., Cramb D., Bazett-Jones D. P., Lees-Miller S. P., The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation. Biochemistry 2002 41 42 12706 12714 2-s2.0-0037159220 10.1021/bi0263558 (Pubitemid 35192499)
    • (2002) Biochemistry , vol.41 , Issue.42 , pp. 12706-12714
    • Merkle, D.1    Douglas, P.2    Moorhead, G.B.G.3    Leonenko, Z.4    Yu, Y.5    Cramb, D.6    Bazett-Jones, D.P.7    Lees-Miller, S.P.8
  • 31
    • 34248231265 scopus 로고    scopus 로고
    • Trans autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining
    • DOI 10.1128/MCB.02366-06
    • Meek K., Douglas P., Cui X., Ding Q., Lees-Miller S. P., Trans autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining. Molecular and Cellular Biology 2007 27 10 3881 3890 2-s2.0-34248231265 10.1128/MCB.02366-06 (Pubitemid 46726193)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.10 , pp. 3881-3890
    • Meek, K.1    Douglas, P.2    Cui, X.3    Ding, Q.4    Lees-Miller, S.P.5
  • 32
    • 0043133778 scopus 로고    scopus 로고
    • Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
    • DOI 10.1128/MCB.23.16.5836-5848.2003
    • Ding Q., Reddy Y. V. R., Wang W., Woods T., Douglas P., Ramsden D. A., Lees-Miller S. P., Meek K., Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Molecular and Cellular Biology 2003 23 16 5836 5848 2-s2.0-0043133778 10.1128/MCB.23.16.5836-5848.2003 (Pubitemid 36951345)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.16 , pp. 5836-5848
    • Ding, Q.1    Reddy, Y.V.R.2    Wang, W.3    Woods, T.4    Douglas, P.5    Ramsden, D.A.6    Lees-Miller, S.P.7    Meek, K.8
  • 33
    • 59849089955 scopus 로고    scopus 로고
    • Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
    • 2-s2.0-59849089955 10.1042/BJ20080413
    • Mahaney B. L., Meek K., Lees-Miller S. P., Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochemical Journal 2009 417 3 639 650 2-s2.0-59849089955 10.1042/BJ20080413
    • (2009) Biochemical Journal , vol.417 , Issue.3 , pp. 639-650
    • Mahaney, B.L.1    Meek, K.2    Lees-Miller, S.P.3
  • 34
    • 28544448011 scopus 로고    scopus 로고
    • Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice
    • DOI 10.1128/MCB.25.24.10842-10852.2005
    • Cui X., Yu Y., Gupta S., Cho Y.-M., Lees-Miller S. P., Meek K., Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice. Molecular and Cellular Biology 2005 25 24 10842 10852 2-s2.0-28544448011 10.1128/MCB.25.24. 10842-10852.2005 (Pubitemid 41747129)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.24 , pp. 10842-10852
    • Xiaoping, C.1    Yaping, Y.2    Gupta, S.3    Cho, Y.-M.4    Lees-Miller, S.P.5    Meek, K.6
  • 35
    • 2242484657 scopus 로고    scopus 로고
    • Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase
    • DOI 10.1042/BJ20020973
    • Douglas P., Sapkota G. P., Morrice N., Yu Y., Goodarzi A. A., Merkle D., Meek K., Alessi D. R., Lees-Miller S. P., Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase. Biochemical Journal 2002 368 1 243 251 2-s2.0-2242484657 10.1042/BJ20020973 (Pubitemid 35463427)
    • (2002) Biochemical Journal , vol.368 , Issue.1 , pp. 243-251
    • Douglas, P.1    Sapkota, G.P.2    Morrice, N.3    Yu, Y.4    Goodarzi, A.A.5    Merkle, D.6    Meek, K.7    Alessi, D.R.8    Lees-Miller, S.P.9
  • 36
    • 33847185190 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase catalytic subunit is phosphorylated in vivo on threonine 3950, a highly conserved amino acid in the protein kinase domain
    • 2-s2.0-33847185190 10.1128/MCB.01962-06
    • Douglas P., Cui X., Block W. D., Yu T., Gupta S., Ding Q., Ye R., Morrice N., Lees-Miller S. P., Meek K., The DNA-dependent protein kinase catalytic subunit is phosphorylated in vivo on threonine 3950, a highly conserved amino acid in the protein kinase domain. Molecular and Cellular Biology 2007 27 5 1581 1591 2-s2.0-33847185190 10.1128/MCB.01962-06
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.5 , pp. 1581-1591
    • Douglas, P.1    Cui, X.2    Block, W.D.3    Yu, T.4    Gupta, S.5    Ding, Q.6    Ye, R.7    Morrice, N.8    Lees-Miller, S.P.9    Meek, K.10
  • 38
    • 0032972734 scopus 로고    scopus 로고
    • DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer
    • DOI 10.1021/bi982584b
    • Chan D. W., Ye R. Q., Veillette C. J., Lees-Miller S. P., DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer. Biochemistry 1999 38 6 1819 1828 2-s2.0-0032972734 10.1021/bi982584b (Pubitemid 29085331)
    • (1999) Biochemistry , vol.38 , Issue.6 , pp. 1819-1828
    • Chan, D.W.1    Ye, R.2    Veillette, C.J.3    Lees-Miller, S.P.4
  • 39
    • 0031939411 scopus 로고    scopus 로고
    • The XRCC4 gene product is a target for and interacts with the DNA- dependent protein kinase
    • DOI 10.1074/jbc.273.3.1794
    • Leber R., Wise T. W., Mizuta R., Meek K., The XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinase. Journal of Biological Chemistry 1998 273 3 1794 1801 2-s2.0-0031939411 10.1074/jbc.273.3. 1794 (Pubitemid 28133713)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.3 , pp. 1794-1801
    • Leber, R.1    Wise, T.W.2    Mizuta, R.3    Meek, K.4
  • 40
    • 0242268028 scopus 로고    scopus 로고
    • DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination
    • DOI 10.1016/S1568-7864(03)00143-5
    • Yu Y. P., Wang W., Ding Q., Ye R., Chen D., Merkle D., Schriemer D., Meek K., Lees-Miller S. P., DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination. DNA Repair 2003 2 11 1239 1252 2-s2.0-0242268028 10.1016/S1568-7864(03)00143-5 (Pubitemid 37340180)
    • (2003) DNA Repair , vol.2 , Issue.11 , pp. 1239-1252
    • Yu, Y.1    Wang, W.2    Ding, Q.3    Ye, R.4    Chen, D.5    Merkle, D.6    Schriemer, D.7    Meek, K.8    Lees-Miller, S.P.9
  • 41
    • 14844292557 scopus 로고    scopus 로고
    • DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks
    • DOI 10.1074/jbc.M410746200
    • Drouet J., Delteil C., Lefranois J., Concannon P., Salles B., Calsou P., DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks. Journal of Biological Chemistry 2005 280 8 7060 7069 2-s2.0-14844292557 10.1074/jbc.M410746200 (Pubitemid 40341262)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.8 , pp. 7060-7069
    • Drouet, J.1    Delteil, C.2    Lefrancois, J.3    Concannon, P.4    Salles, B.5    Calsou, P.6
  • 42
    • 13844321898 scopus 로고    scopus 로고
    • Phosphorylation of linker histones by DNA-dependent protein kinase is required for DNA ligase IV-dependent ligation in the presence for histone H1
    • DOI 10.1073/pnas.0401179102
    • Kysela B., Chovanec M., Jeggo P. A., Phosphorylation of linker histones by DNA-dependent protein kinase is required for DNA ligase IV-dependent ligation in the presence for histone H1. Proceedings of the National Academy of Sciences of the United States of America 2005 102 6 1877 1882 2-s2.0-13844321898 10.1073/pnas.0401179102 (Pubitemid 40261980)
    • (2005) Proceedings of the National Academy of Sciences of the United States of America , vol.102 , Issue.6 , pp. 1877-1882
    • Kysela, B.1    Chovanec, M.2    Jeggo, P.A.3
  • 43
    • 74049134920 scopus 로고    scopus 로고
    • Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex
    • 2-s2.0-70349472553 10.1074/jbc.M109.065615
    • Hammel M., mhammel@lbl.gov Yu Y., Mahaney B. L., Cai B., Ye R., Phipps B. M., Rambo R. P., Hura G. L., Pelikan M., So S., Abolfath R. M., Chen D. J., Lees-Miller S.P., leesmill@ucalgary.ca Tainer J. A., Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. Journal of Biological Chemistry 2010 285 2 1414 1423 2-s2.0-70349472553 10.1074/jbc.M109.065615
    • (2010) Journal of Biological Chemistry , vol.285 , Issue.2 , pp. 1414-1423
    • Hammel, M.1    Tainer, J.A.2
  • 44
    • 73849140503 scopus 로고    scopus 로고
    • Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats
    • 2-s2.0-0030501419 10.1038/nature08648
    • Sibanda B. L., lynn@cryst.bioc.cam.ac.uk Chirgadze D. Y., dima@cryst.bioc.cam.ac.uk Blundell T. L., Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats. Nature 2010 463 7277 118 121 2-s2.0-0030501419 10.1038/nature08648
    • (2010) Nature , vol.463 , Issue.7277 , pp. 118-121
    • Sibanda, B.L.1    Blundell, T.L.2
  • 45
    • 57949116437 scopus 로고    scopus 로고
    • DNA-PK: The means to justify the ends?
    • 2-s2.0-57949116437 10.1016/S0065-2776(08)00602-0
    • Meek K., Dang V., Lees-Miller S. P., DNA-PK: the means to justify the ends? Advances in Immunology 2008 99 33 58 2-s2.0-57949116437 10.1016/S0065-2776(08)00602-0
    • (2008) Advances in Immunology , vol.99 , pp. 33-58
    • Meek, K.1    Dang, V.2    Lees-Miller, S.P.3
  • 46
    • 0034732239 scopus 로고    scopus 로고
    • Dna repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
    • DOI 10.1038/35006670
    • Difilippantonio M. J., Zhu J., Chen H. T., Meffre E., Nussenzweig M. C., Max E. E., Ried T., Nussenzweig A., Dna repair protein Ku80 suppresses chromosomal aberrations and malignant transformation. Nature 2000 404 6777 510 514 2-s2.0-0034732239 10.1038/35006670 (Pubitemid 30186895)
    • (2000) Nature , vol.404 , Issue.6777 , pp. 510-514
    • Difilippantonio, M.J.1    Zhu, J.2    Chen, H.T.3    Meffre, E.4    Nussenzweig, M.C.5    Max, E.E.6    Ried, T.7    Nussenzweig, A.8
  • 48
  • 50
    • 0029612225 scopus 로고
    • Repair of x-ray-induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: Joining of correct and incorrect ends
    • DOI 10.1073/pnas.92.26.12050
    • Löbrich M., Rydberg B., Cooper P. K., Repair of X-ray-induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: joining of correct and incorrect ends. Proceedings of the National Academy of Sciences of the United States of America 1995 92 26 12050 12054 2-s2.0-0029612225 10.1073/pnas.92.26.12050 (Pubitemid 26014009)
    • (1995) Proceedings of the National Academy of Sciences of the United States of America , vol.92 , Issue.26 , pp. 12050-12054
    • Lobrich, M.1    Rydberg, B.2    Cooper, P.K.3
  • 51
    • 0034162719 scopus 로고    scopus 로고
    • DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus
    • DiBiase S. J., Zeng Z.-C., Chen R., Hyslop T., Curran W. J. Jr., Iliakis G., DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus. Cancer Research 2000 60 5 1245 1253 2-s2.0-0034162719 (Pubitemid 30151991)
    • (2000) Cancer Research , vol.60 , Issue.5 , pp. 1245-1253
    • DiBiase, S.J.1    Zeng, Z.-C.2    Chen, R.3    Hyslop, T.4    Curran Jr., W.J.5    Iliakis, G.6
  • 52
    • 0344012187 scopus 로고    scopus 로고
    • Biochemical evidence for Ku-independent backup pathways of NHEJ
    • DOI 10.1093/nar/gkg728
    • Wang H. C., Perrault A. R., Takeda Y., Qin W., Wang H., Iliakis G., Biochemical evidence for Ku-independent backup pathways of NHEJ. Nucleic Acids Research 2003 31 18 5377 5388 2-s2.0-0344012187 10.1093/nar/gkg728 (Pubitemid 37441906)
    • (2003) Nucleic Acids Research , vol.31 , Issue.18 , pp. 5377-5388
    • Wang, H.1    Perrault, A.R.2    Takeda, Y.3    Qin, W.4    Wang, H.5    Iliakis, G.6
  • 53
    • 0000391880 scopus 로고    scopus 로고
    • Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle
    • Lee S. E., Mitchell R. A., Cheng A., Hendrickson E. A., Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle. Molecular and Cellular Biology 1997 17 3 1425 1433 2-s2.0-0000391880 (Pubitemid 27097371)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.3 , pp. 1425-1433
    • Lee, S.E.1    Mitchell, R.A.2    Cheng, A.3    Hendrickson, E.A.4
  • 54
    • 11244277456 scopus 로고    scopus 로고
    • Backup pathways of NHEJ are suppressed by DNA-PK
    • DOI 10.1002/jcb.20104
    • Perrault R., Wang H., Wang M., Rosidi B., Iliakis G., Backup pathways of NHEJ are suppressed by DNA-PK. Journal of Cellular Biochemistry 2004 92 4 781 794 2-s2.0-11244277456 10.1002/jcb.20104 (Pubitemid 44264268)
    • (2004) Journal of Cellular Biochemistry , vol.92 , Issue.4 , pp. 781-794
    • Perrault, R.1    Wang, H.2    Wang, M.3    Rosidi, B.4    Iliakis, G.5
  • 55
    • 69949173301 scopus 로고    scopus 로고
    • Backup pathways of NHEJ in cells of higher eukaryotes: Cell cycle dependence
    • 2-s2.0-69949173301 10.1016/j.radonc.2009.06.024
    • Iliakis G., Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence. Radiotherapy and Oncology 2009 92 3 310 315 2-s2.0-69949173301 10.1016/j.radonc.2009.06.024
    • (2009) Radiotherapy and Oncology , vol.92 , Issue.3 , pp. 310-315
    • Iliakis, G.1
  • 57
    • 11244280890 scopus 로고    scopus 로고
    • Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
    • DOI 10.1074/jbc.M404524200
    • Audebert M., Salles B., Calsou P., Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining. Journal of Biological Chemistry 2004 279 53 55117 55126 2-s2.0-11244280890 10.1074/jbc.M404524200 (Pubitemid 40066505)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.53 , pp. 55117-55126
    • Audebert, M.1    Salles, B.2    Calsou, P.3
  • 58
    • 20144363082 scopus 로고    scopus 로고
    • DNA ligase III as a candidate component of backup pathways of nonhomologous end joining
    • DOI 10.1158/0008-5472.CAN-04-3055
    • Wang H., Rosidi B., Perrault R., Wang M., Zhang L., Windhofer F., Iliakis G., DNA ligase III as a candidate component of backup pathways of nonhomologous end joining. Cancer Research 2005 65 10 4020 4030 2-s2.0-20144363082 10.1158/0008-5472.CAN-04-3055 (Pubitemid 40775638)
    • (2005) Cancer Research , vol.65 , Issue.10 , pp. 4020-4030
    • Wang, H.1    Rosidi, B.2    Perrault, R.3    Wang, M.4    Zhang, L.5    Windhofer, F.6    Iliakis, G.7
  • 59
    • 33845657443 scopus 로고    scopus 로고
    • PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
    • DOI 10.1093/nar/gkl840
    • Wang M., Wu W., Wu W., Rosidi B., Zhang L., Wang H., Iliakis G., PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways. Nucleic Acids Research 2006 34 21 6170 6182 2-s2.0-33845657443 10.1093/nar/gkl840 (Pubitemid 44942738)
    • (2006) Nucleic Acids Research , vol.34 , Issue.21 , pp. 6170-6182
    • Wang, M.1    Wu, W.2    Wu, W.3    Rosidi, B.4    Zhang, L.5    Wang, H.6    Iliakis, G.7
  • 60
    • 41149176120 scopus 로고    scopus 로고
    • Histone H1 functions as a stimulatory factor in backup pathways of NHEJ
    • DOI 10.1093/nar/gkn013
    • Rosidi B., Wang M., Wu W., Sharma A., Wang H., Iliakis G., Histone H1 functions as a stimulatory factor in backup pathways of NHEJ. Nucleic Acids Research 2008 36 5 1610 1623 2-s2.0-41149176120 10.1093/nar/gkn013 (Pubitemid 351426113)
    • (2008) Nucleic Acids Research , vol.36 , Issue.5 , pp. 1610-1623
    • Rosidi, B.1    Wang, M.2    Wu, W.3    Sharma, A.4    Wang, H.5    Iliakis, G.6
  • 61
    • 0031925138 scopus 로고    scopus 로고
    • Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells
    • DOI 10.2307/3579783
    • Okayasu R., Suetomi K., Ullrich R. L., Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells. Radiation Research 1998 149 5 440 445 2-s2.0-0031925138 10.2307/3579783 (Pubitemid 28193783)
    • (1998) Radiation Research , vol.149 , Issue.5 , pp. 440-445
    • Okayasu, R.1    Suetomi, K.2    Ullrich, R.L.3
  • 62
    • 0032916940 scopus 로고    scopus 로고
    • Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks
    • DOI 10.2307/3579766
    • Chernikova S. B., Wells R. L., Elkind M. M., Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks. Radiation Research 1999 151 2 159 166 2-s2.0-0032916940 10.2307/3579766 (Pubitemid 29061958)
    • (1999) Radiation Research , vol.151 , Issue.2 , pp. 159-166
    • Chernikova, S.B.1    Wells, R.L.2    Elkind, M.M.3
  • 63
    • 0032971199 scopus 로고    scopus 로고
    • Absence of DNA ligase IV protein in XR-1 cells: Evidence for stabilization by XRCC4
    • DOI 10.1016/S0921-8777(98)00063-9, PII S0921877798000639
    • Bryans M., Valenzano M. C., Stamato T. D., Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4. Mutation Research 1999 433 1 53 58 2-s2.0-0032971199 10.1016/S0921-8777(98)00063-9 (Pubitemid 29073670)
    • (1999) Mutation Research - DNA Repair , vol.433 , Issue.1 , pp. 53-58
    • Bryans, M.1    Valenzano, M.C.2    Stamato, T.D.3
  • 64
    • 0027943344 scopus 로고
    • Macromolecular crowding effects on the interaction of DNA with Escherichia coli DNA-binding proteins: A model for bacterial nucleoid stabilization
    • DOI 10.1016/0167-4781(94)90049-3
    • Murphy L. D., Zimmerman S. B., Macromolecular crowding effects on the interaction of DNA with Escherichia coli DNA-binding proteins: a model for bacterial nucleoid stabilization. Biochimica et Biophysica Acta 1994 1219 2 277 284 2-s2.0-0027943344 10.1016/0167-4781(94)90049-3 (Pubitemid 24319684)
    • (1994) Biochimica et Biophysica Acta - Gene Structure and Expression , vol.1219 , Issue.2 , pp. 277-284
    • Murphy, L.D.1    Zimmerman, S.B.2
  • 66
    • 0035815743 scopus 로고    scopus 로고
    • The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media
    • DOI 10.1074/jbc.R100005200
    • Minton A. P., The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media. Journal of Biological Chemistry 2001 276 14 10577 10580 2-s2.0-0035815743 10.1074/jbc.R100005200 (Pubitemid 38089223)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.14 , pp. 10577-10580
    • Minton, A.P.1
  • 67
    • 0035882894 scopus 로고    scopus 로고
    • In vitro repair of complex unligatable oxidatively induced DNA double-strand breaks by human cell extracts
    • article e78 2-s2.0-0035882894
    • Pastwa E., Neumann R. D., Winters T. A., In vitro repair of complex unligatable oxidatively induced DNA double-strand breaks by human cell extracts. Nucleic Acids Research 2001 29 16, article e78 2-s2.0-0035882894
    • (2001) Nucleic Acids Research , vol.29 , Issue.16
    • Pastwa, E.1    Neumann, R.D.2    Winters, T.A.3
  • 68
    • 0033104498 scopus 로고    scopus 로고
    • Structure of DNA-dependent protein kinase: Implications for its regulation by DNA
    • Leuther K. K., Hammarsten O., Kornberg R. D., Chu G., Structure of DNA-dependent protein kinase: implications for its regulation by DNA. The EMBO Journal 1999 18 5 1114 1123 2-s2.0-0033104498 (Pubitemid 29110297)
    • (1999) EMBO Journal , vol.18 , Issue.5 , pp. 1114-1123
    • Leuther, K.K.1    Hammarsten, O.2    Kornberg, R.D.3    Chu, G.4
  • 69
    • 33749426759 scopus 로고    scopus 로고
    • An in vitro nonhomologous end-joining assay using linear duplex oligonucleotides
    • DOI 10.1016/j.ab.2006.06.035, PII S0003269706004714
    • Datta K., Neumann R. D., Winters T. A., An in vitro nonhomologous end-joining assay using linear duplex oligonucleotides. Analytical Biochemistry 2006 358 1 155 157 2-s2.0-33749426759 10.1016/j.ab.2006.06.035 (Pubitemid 44511892)
    • (2006) Analytical Biochemistry , vol.358 , Issue.1 , pp. 155-157
    • Datta, K.1    Neumann, R.D.2    Winters, T.A.3
  • 70
    • 0032518680 scopus 로고    scopus 로고
    • Ku protein stimulates DNA end joining by mammalian DNA ligases: A direct role for Ku in repair of DNA double-strand breaks
    • DOI 10.1093/emboj/17.2.609
    • Ramsden D. A., Geliert M., Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks. The EMBO Journal 1998 17 2 609 614 2-s2.0-0032518680 10.1093/emboj/17.2.609 (Pubitemid 28045500)
    • (1998) EMBO Journal , vol.17 , Issue.2 , pp. 609-614
    • Ramsden, D.A.1    Geliert, M.2
  • 71
    • 0023219316 scopus 로고
    • Replacement of potassium chloride by potassium glutamate dramatically enhances protein-DNA interactions in vitro
    • DOI 10.1021/bi00382a006
    • Leirmo S., Harrison C., Cayley D. S., Burgess R. R., Record M. T. Jr., Replacement of potassium chloride by potassium glutamate dramatically enhances protein-DNA interactions in vitro. Biochemistry 1987 26 8 2095 2101 2-s2.0-0023219316 (Pubitemid 17080958)
    • (1987) Biochemistry , vol.26 , Issue.8 , pp. 2095-2101
    • Leirmo, S.1    Harrison, C.2    Cayley, D.S.3
  • 72
    • 0030727624 scopus 로고    scopus 로고
    • The Hofmeister series: Salt and solvent effects on interfacial phenomena
    • DOI 10.1017/S0033583597003363
    • Cacace M. G., Landau E. M., Ramsden J. J., The Hofmeister series: salt and solvent effects on interfacial phenomena. Quarterly Reviews of Biophysics 1997 30 3 241 277 2-s2.0-0030727624 10.1017/S0033583597003363 (Pubitemid 27491348)
    • (1997) Quarterly Reviews of Biophysics , vol.30 , Issue.3 , pp. 241-277
    • Cacace, M.G.1    Landau, E.M.2    Ramsden, J.J.3
  • 73
    • 0031930488 scopus 로고    scopus 로고
    • DNA-dependent protein kinase: DNA binding and activation in the absence of Ku
    • DOI 10.1073/pnas.95.2.525
    • Hammarsten O., Chu G., DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proceedings of the National Academy of Sciences of the United States of America 1998 95 2 525 530 2-s2.0-0031930488 10.1073/pnas.95.2.525 (Pubitemid 28083776)
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.2 , pp. 525-530
    • Hammarsten, O.1    Chu, G.2
  • 74
    • 0024402712 scopus 로고
    • Glutamate overcomes the salt inhibition of DNA polymerase III holoenzyme
    • Griep M. A., McHenry C. S., Glutamate overcomes the salt inhibition of DNA polymerase III holoenzyme. Journal of Biological Chemistry 1989 264 19 11294 11301 2-s2.0-0024402712 (Pubitemid 19168864)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.19 , pp. 11294-11301
    • Griep, M.A.1    McHenry, C.S.2
  • 75
    • 0037099520 scopus 로고    scopus 로고
    • Deficient nonhomologous end-joining activity in cell-free extracts from BRCA1-null fibroblasts
    • Zhong Q., Boyer T. G., Chen P.-L., Lee W.-H., Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts. Cancer Research 2002 62 14 3966 3970 2-s2.0-0037099520 (Pubitemid 34791061)
    • (2002) Cancer Research , vol.62 , Issue.14 , pp. 3966-3970
    • Zhong, Q.1    Boyer, T.G.2    Chen, P.-L.3    Lee, W.-H.4


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