Selection of objective function in genome scale flux balance analysis for process feed development in antibiotic production

Metabolic Engineering

Volumn 10, Issue 5, 2008, Pages 227-233

  Khannapho, Chiraphan ^a   Zhao, Hongjuan ^a   Bonde, Bhushan K ^a   Kierzek, Andrzej M ^a   Avignone Rossa, Claudio A ^a   Bushell, Michael E ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Genome scale; Metabolic flux variability analysis; Process feed design; Streptomyces coelicolor

Indexed keywords

GLUCOSE; RATE CONSTANTS;

ACTINORHODIN; ANTIBIOTIC PRODUCTION; ASSIMILATION RATES; FLUX BALANCE ANALYSIS; FLUX VARIABILITY; GENOME SCALE; GENOME-SCALE METABOLIC NETWORK; GLUCOSE UPTAKE; IN SILICO PREDICTIONS; IN-PROCESS; IN-VIVO; METABOLIC FLUX VARIABILITY ANALYSIS; OBJECTIVE FUNCTION; OPTIMISATION; PROCESS FEED DESIGN; ROBUSTNESS ANALYSIS; STREPTOMYCES COELICOLOR;

ANTIBIOTICS;

ACTINORHODINE; GLUCOSE;

ARTICLE; CHEMICAL REACTION; COMPUTER MODEL; DRUG MANUFACTURE; GENE FUNCTION; GENOME; NONHUMAN; PRIORITY JOURNAL; STREPTOMYCES COELICOLOR;

ANTHRAQUINONES; ANTI-BACTERIAL AGENTS; ENERGY METABOLISM; GENOME, BACTERIAL; GLUCOSE; STREPTOMYCES COELICOLOR;

STREPTOMYCES COELICOLOR;

EID: 50249113230     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2008.06.003     Document Type: Article

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