메뉴 건너뛰기




Volumn 220, Issue 2, 2003, Pages 295-301

Analysis of metabolic and physiological responses to gnd knockout in Escherichia coli by using C-13 tracer experiment and enzyme activity measurement

Author keywords

13C tracer experiment; Enzyme activity; Gene deletion; Metabolic response; Pentose phosphate pathway

Indexed keywords

CARBON 13; GLUCOSE 6 PHOSPHATE ISOMERASE; PHOSPHOENOLPYRUVATE CARBOXYLASE;

EID: 0037470940     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(03)00133-2     Document Type: Article
Times cited : (46)

References (20)
  • 2
    • 0035856579 scopus 로고    scopus 로고
    • Metabolic flux response to phosphoglucose isomerase knock-out in Escherichia coli and impact of overexpression of the soluble transhydrogenase UdhA
    • Canonaco F., Hess T.A., Heri S., Wang T., Szyperski T., Sauer U. Metabolic flux response to phosphoglucose isomerase knock-out in Escherichia coli and impact of overexpression of the soluble transhydrogenase UdhA. FEMS Microbiol. Lett. 204:2001;247-252.
    • (2001) FEMS Microbiol. Lett. , vol.204 , pp. 247-252
    • Canonaco, F.1    Hess, T.A.2    Heri, S.3    Wang, T.4    Szyperski, T.5    Sauer, U.6
  • 3
    • 0014272137 scopus 로고
    • Selection of mutants lacking glucose-6-phosphate dehydrogenase or gluconate-6-phosphate dehydrogenase
    • Fraenkel D.G. Selection of mutants lacking glucose-6-phosphate dehydrogenase or gluconate-6-phosphate dehydrogenase. J. Bacteriol. 95:1968;1267-1271.
    • (1968) J. Bacteriol. , vol.95 , pp. 1267-1271
    • Fraenkel, D.G.1
  • 4
    • 0028884775 scopus 로고
    • Genetics of pentose-phosphate pathway enzymes of Escherichia coli K12
    • Sprenger G.A. Genetics of pentose-phosphate pathway enzymes of Escherichia coli K12. Arch. Microbiol. 164:1995;324-330.
    • (1995) Arch. Microbiol. , vol.164 , pp. 324-330
    • Sprenger, G.A.1
  • 5
    • 0033586461 scopus 로고    scopus 로고
    • Mass spectrometry for metabolic flux analysis
    • Wittmann C., Heinzle E. Mass spectrometry for metabolic flux analysis. Biotechnol. Bioeng. 62:1999;739-750.
    • (1999) Biotechnol. Bioeng. , vol.62 , pp. 739-750
    • Wittmann, C.1    Heinzle, E.2
  • 6
    • 0030050268 scopus 로고    scopus 로고
    • Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing
    • Marx A., Graaf A.A., Wiechert W., Eggeling L., Sahm H. Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing. Biotechnol. Bioeng. 49:1996;111-129.
    • (1996) Biotechnol. Bioeng. , vol.49 , pp. 111-129
    • Marx, A.1    Graaf, A.A.2    Wiechert, W.3    Eggeling, L.4    Sahm, H.5
  • 7
    • 0035212187 scopus 로고    scopus 로고
    • Innovations in generation and analysis of 2D [(13)C, (1)H] COSY NMR spectra for metabolic flux analysis purposes
    • Winden V., Schipper D., Verheijen P., Heijnen J. Innovations in generation and analysis of 2D [(13)C, (1)H] COSY NMR spectra for metabolic flux analysis purposes. Metab. Eng. 3:2001;322-343.
    • (2001) Metab. Eng. , vol.3 , pp. 322-343
    • Winden, V.1    Schipper, D.2    Verheijen, P.3    Heijnen, J.4
  • 8
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K12 using PCR products
    • Datsenko K.A., Wanner B.L. One-step inactivation of chromosomal genes in Escherichia coli K12 using PCR products. Proc. Natl. Acad. Sci. USA. 97:2000;6640-6645.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 9
    • 0003265168 scopus 로고    scopus 로고
    • 13C-labeled acetate and glucose using GC-MS and powerful flux calculation method
    • in press
    • 13C-labeled acetate and glucose using GC-MS and powerful flux calculation method. J. Biotechnol., in press.
    • (2002) J. Biotechnol.
    • Zhao, J.1    Shimizu, K.2
  • 10
    • 0034847930 scopus 로고    scopus 로고
    • Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis
    • Dauner M., Bailey J.E., Sauer U. Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis. Biotechnol. Bioeng. 76:2001;144-156.
    • (2001) Biotechnol. Bioeng. , vol.76 , pp. 144-156
    • Dauner, M.1    Bailey, J.E.2    Sauer, U.3
  • 12
    • 0032753923 scopus 로고    scopus 로고
    • Metabolic flux ratio analyis of genetic and environmental modulations of Escherichia coli central carbon metabolism
    • Sauer U., Lasko D.R., Fiaux J., Hochuli M., Glaser R., Szyperski K.W., Bailey J.E. Metabolic flux ratio analyis of genetic and environmental modulations of Escherichia coli central carbon metabolism. J. Bacteriol. 181:1999;6679-6688.
    • (1999) J. Bacteriol. , vol.181 , pp. 6679-6688
    • Sauer, U.1    Lasko, D.R.2    Fiaux, J.3    Hochuli, M.4    Glaser, R.5    Szyperski, K.W.6    Bailey, J.E.7
  • 13
    • 0012715483 scopus 로고
    • Preparation and assay of enzymes
    • Colowick S.P. Preparation and assay of enzymes. Methods Enzymol. 6:1963;1-640.
    • (1963) Methods Enzymol. , vol.6 , pp. 1-640
    • Colowick, S.P.1
  • 14
    • 0029146299 scopus 로고
    • 13C-labeling of proteinogenic amino acids - An efficient analytical tool to investigate intermediary metabolism
    • 13C-labeling of proteinogenic amino acids - An efficient analytical tool to investigate intermediary metabolism. Eur. J. Biochem. 232:1995;433-448.
    • (1995) Eur. J. Biochem. , vol.232 , pp. 433-448
    • Szyperski, T.1
  • 15
    • 0026204952 scopus 로고
    • Mass isotopomer analysis: Theoretical and practical consideration
    • Paul Lee W.N. Mass isotopomer analysis: theoretical and practical consideration. Biol. Mass Spectrometry. 20:1991;451-458.
    • (1991) Biol. Mass Spectrometry , vol.20 , pp. 451-458
    • Paul Lee, W.N.1
  • 16
    • 0032838693 scopus 로고    scopus 로고
    • Quantitative analysis of metabolic fluxes in Escherichia coli using two-dimensional NMR spectroscopy and complete isotopomer models
    • Schmidt K., Nielsen J., Villadsen J. Quantitative analysis of metabolic fluxes in Escherichia coli using two-dimensional NMR spectroscopy and complete isotopomer models. J. Biotechnol. 71:1999;175-190.
    • (1999) J. Biotechnol. , vol.71 , pp. 175-190
    • Schmidt, K.1    Nielsen, J.2    Villadsen, J.3
  • 18
    • 0343471424 scopus 로고    scopus 로고
    • Modeling isotopomer distributions in metabolic networks using isotopomer mapping matrices
    • Schmidt K., Nielsen J., Villadsen J. Modeling isotopomer distributions in metabolic networks using isotopomer mapping matrices. Biotechnol. Bioeng. 55:1997;831-840.
    • (1997) Biotechnol. Bioeng. , vol.55 , pp. 831-840
    • Schmidt, K.1    Nielsen, J.2    Villadsen, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.