-
1
-
-
0033600240
-
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
-
Agami, R., G. Blandino, M. Oren, Y. Shaul (1999) Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis. Nature 399:809-813.
-
(1999)
Nature
, vol.399
, pp. 809-813
-
-
Agami, R.1
Blandino, G.2
Oren, M.3
Shaul, Y.4
-
2
-
-
72749120841
-
Activated Abl kinase inhibits oncogenic TGF-β signaling and tumorigenesis in mammary tumors
-
Allington, T. M., A. J. Galliher-Beckley, W. P. Schiemann (2009) Activated Abl kinase inhibits oncogenic TGF-β signaling and tumorigenesis in mammary tumors. FASEB J 23:4231-4243.
-
(2009)
FASEB J.
, vol.23
, pp. 4231-4243
-
-
Allington, T.M.1
Galliher-Beckley, A.J.2
Schiemann, W.P.3
-
3
-
-
0034711307
-
Phosphatidylinositol 3-kinase function is required for TGF-β-mediated epithelial to mesenchymal transition and cell migration
-
Bakin, A. V., A. K. Tomlinson, N. A. Bhowmick, H. L. Moses, C. L. Arteaga (2000) Phosphatidylinositol 3-kinase function is required for TGF-β-mediated epithelial to mesenchymal transition and cell migration. J Biol Chem 275:36803-36810.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36803-36810
-
-
Bakin, A.V.1
Tomlinson, A.K.2
Bhowmick, N.A.3
Moses, H.L.4
Arteaga, C.L.5
-
5
-
-
0030925565
-
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
-
Baskaran, R., L. D. Wood, L. L. Whitaker, C. E. Canman, S. E. Morgan, Y. Xu, C. Barlow, D. Baltimore, A. Wynshaw-Boris, M. B. Kastan, JY. Wang (1997) Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature 387:516-519.
-
(1997)
Nature
, vol.387
, pp. 516-519
-
-
Baskaran, R.1
Wood, L.D.2
Whitaker, L.L.3
Canman, C.E.4
Morgan, S.E.5
Xu, Y.6
Barlow, C.7
Baltimore, D.8
Wynshaw-Boris, A.9
Kastan, M.B.10
Wang, J.Y.11
-
6
-
-
1642359815
-
Role of TGF-β in breast carcinogenesis
-
Benson, J. R. (2004) Role of TGF-β in breast carcinogenesis. Lancet Oncol 5:229-239.
-
(2004)
Lancet Oncol.
, vol.5
, pp. 229-239
-
-
Benson, J.R.1
-
7
-
-
0842288323
-
TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
-
Bhowmick, N. A., A. Chytil, D. Plieth, A. E. Gorska, N. Dumont, S. Shappell, M. K. Washington, E. G. Neilson, H. L. Moses (2004a) TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 303:848-851.
-
(2004)
Science
, vol.303
, pp. 848-851
-
-
Bhowmick, N.A.1
Chytil, A.2
Plieth, D.3
Gorska, A.E.4
Dumont, N.5
Shappell, S.6
Washington, M.K.7
Neilson, E.G.8
Moses, H.L.9
-
8
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
Bhowmick, N. A., E. G. Neilson, H. L. Moses (2004b) Stromal fibroblasts in cancer initiation and progression. Nature 432:332-337.
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
10
-
-
33745515023
-
Tumour microenvironment: TGF-β: The molecular Jekyll and Hyde of cancer
-
Bierie, B., H. L. Moses (2006) Tumour microenvironment: TGF-β: the molecular Jekyll and Hyde of cancer. Nat Rev Cancer 6:506-520.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 506-520
-
-
Bierie, B.1
Moses, H.L.2
-
11
-
-
33847770211
-
TGF-β signaling in breast cancer
-
Buck, M. B., C. Knabbe (2006) TGF-β signaling in breast cancer. Ann NY Acad Sci 1089:119-126.
-
(2006)
Ann. NY Acad. Sci.
, vol.1089
, pp. 119-126
-
-
Buck, M.B.1
Knabbe, C.2
-
13
-
-
2942564711
-
Tumor necrosis factor-α-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation
-
Chau, B. N., T. T. Chen, Y. Y. Wan, J. DeGregori, JY. Wang (2004) Tumor necrosis factor-α-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation. Mol Cell Biol 24:4438-4447.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4438-4447
-
-
Chau, B.N.1
Chen, T.T.2
Wan, Y.Y.3
DeGregori, J.4
Wang, J.Y.5
-
14
-
-
33644658126
-
The tyrosine kinase inhibitor imatinib fails to inhibit pancreatic cancer progression
-
Chen, J., C. Rocken, B. Nitsche, C. Hosius, H. Gschaidmeier, S. Kahl, P. Malfertheiner, M. P. Ebert (2006) The tyrosine kinase inhibitor imatinib fails to inhibit pancreatic cancer progression. Cancer Lett 233:328-337.
-
(2006)
Cancer Lett.
, vol.233
, pp. 328-337
-
-
Chen, J.1
Rocken, C.2
Nitsche, B.3
Hosius, C.4
Gschaidmeier, H.5
Kahl, S.6
Malfertheiner, P.7
Ebert, M.P.8
-
15
-
-
23744452875
-
Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP-and HGF-mediated signaling networks
-
Cheng, N., N. A. Bhowmick, A. Chytil, A. E. Gorksa, K. A. Brown, R. Muraoka, CL. Arteaga, E. G. Neilson, S. W. Hayward, H. L. Moses (2005) Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP-and HGF-mediated signaling networks. Oncogene 24:5053-5068.
-
(2005)
Oncogene
, vol.24
, pp. 5053-5068
-
-
Cheng, N.1
Bhowmick, N.A.2
Chytil, A.3
Gorksa, A.E.4
Brown, K.A.5
Muraoka, R.6
Arteaga, C.L.7
Neilson, E.G.8
Hayward, S.W.9
Moses, H.L.10
-
16
-
-
60549115127
-
A phase II study of imatinib mesylate and capecitabine in metastatic breast cancer: Southwest Oncology Group Study 0338
-
Chew, H. K., W. E. Barlow, K. Albain, D. Lew, A. Gown, D. F. Hayes, J. Gralow, G. N. Hortobagyi, R. Livingston (2008) A phase II study of imatinib mesylate and capecitabine in metastatic breast cancer: Southwest Oncology Group Study 0338. Clin Breast Cancer 8:511-515.
-
(2008)
Clin. Breast Cancer
, vol.8
, pp. 511-515
-
-
Chew, H.K.1
Barlow, W.E.2
Albain, K.3
Lew, D.4
Gown, A.5
Hayes, D.F.6
Gralow, J.7
Hortobagyi, G.N.8
Livingston, R.9
-
17
-
-
53049094588
-
Imatinib mesylate (Gleevec) in advanced breast cancer-expressing c-Kit or PDGFR-β: Clinical activity and biological correlations
-
Cristofanilli, M., P. Morandi, S. Krishnamurthy, J. M. Reuben, B. N. Lee, D. Francis, D. J. Booser, M. C Green, B. K. Arun, L. Pusztai, A. Lopez, R. Islam, V. Valero, G. N. Hortobagyi (2008) Imatinib mesylate (Gleevec) in advanced breast cancer-expressing c-Kit or PDGFR-β: clinical activity and biological correlations. Ann Oncol 19:1713-1719.
-
(2008)
Ann. Oncol.
, vol.19
, pp. 1713-1719
-
-
Cristofanilli, M.1
Morandi, P.2
Krishnamurthy, S.3
Reuben, J.M.4
Lee, B.N.5
Francis, D.6
Booser, D.J.7
Green, M.C.8
Arun, B.K.9
Pusztai, L.10
Lopez, A.11
Islam, R.12
Valero, V.13
Hortobagyi, G.N.14
-
18
-
-
15244339164
-
Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis
-
Daniels, C. E., M. C. Wilkes, M. Edens, T. J. Kottom, S. J. Murphy, A. H. Limper, E. B. Leof (2004) Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis. J Clin Invest 114:1308-1316.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1308-1316
-
-
Daniels, C.E.1
Wilkes, M.C.2
Edens, M.3
Kottom, T.J.4
Murphy, S.J.5
Limper, A.H.6
Leof, E.B.7
-
19
-
-
33745081606
-
Circumventing resistance to kinase-inhibitor therapy
-
Druker, B. J. (2006) Circumventing resistance to kinase-inhibitor therapy. N Engl J Med 354:2594-2596.
-
(2006)
N Engl. J. Med.
, vol.354
, pp. 2594-2596
-
-
Druker, B.J.1
-
20
-
-
0035856481
-
Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway
-
Echarri, A., A. M. Pendergast (2001) Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway. Curr Biol 11:1759-1765.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1759-1765
-
-
Echarri, A.1
Pendergast, A.M.2
-
21
-
-
58849126879
-
Three-dimensional context regulation of metastasis
-
Erler, J. T., V. M. Weaver (2009) Three-dimensional context regulation of metastasis. Clin Exp Metastasis 26:35-49.
-
(2009)
Clin. Exp. Metastasis
, vol.26
, pp. 35-49
-
-
Erler, J.T.1
Weaver, V.M.2
-
22
-
-
0035963315
-
Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to hepatocyte growth factor
-
Frasca, F., P. Vigneri, V. Vella, R. Vigneri, JY. Wang (2001) Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to hepatocyte growth factor. Oncogene 20:3845-3856.
-
(2001)
Oncogene
, vol.20
, pp. 3845-3856
-
-
Frasca, F.1
Vigneri, P.2
Vella, V.3
Vigneri, R.4
Wang, J.Y.5
-
23
-
-
33747086130
-
3 integrin and Src facilitate TGF-β mediated induction of epithelial-mesenchymal transition in mammary epithelial cells
-
3 integrin and Src facilitate TGF-β mediated induction of epithelial-mesenchymal transition in mammary epithelial cells. Breast Cancer Res 8: R42.
-
(2006)
Breast Cancer Res.
, vol.8
-
-
Galliher, A.J.1
Schiemann, W.P.2
-
24
-
-
34248584887
-
Src phosphorylates Tyr284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during breast cancer cell proliferation and invasion
-
Galliher, A. J., W. P. Schiemann (2007) Src phosphorylates Tyr284 in TGF-β type II receptor and regulates TGF-β stimulation of p38 MAPK during breast cancer cell proliferation and invasion. Cancer Res 67:3752-3758.
-
(2007)
Cancer Res.
, vol.67
, pp. 3752-3758
-
-
Galliher, A.J.1
Schiemann, W.P.2
-
25
-
-
40549115658
-
Grb2 binding to Tyr284 in TβR-II is essential for mammary tumor growth and metastasis stimulated by TGF-β
-
Galliher-Beckley, A. J., W. P. Schiemann (2008) Grb2 binding to Tyr284 in TβR-II is essential for mammary tumor growth and metastasis stimulated by TGF-β. Carcinogenesis 29:244-251.
-
(2008)
Carcinogenesis
, vol.29
, pp. 244-251
-
-
Galliher-Beckley, A.J.1
Schiemann, W.P.2
-
26
-
-
42549140156
-
A phase II trial of imatinib mesylate in patients with metastatic pancreatic cancer
-
Gharibo, M., L. Patrick-Miller, L. Zheng, L. Guensch, P. Juvidian, E. Poplin (2008) A phase II trial of imatinib mesylate in patients with metastatic pancreatic cancer. Pancreas 36:341-345.
-
(2008)
Pancreas
, vol.36
, pp. 341-345
-
-
Gharibo, M.1
Patrick-Miller, L.2
Zheng, L.3
Guensch, L.4
Juvidian, P.5
Poplin, E.6
-
27
-
-
0035913192
-
Role for c-Abl and p73 in the radiation response of male germ cells
-
Hamer, G., I. S. Gademan, H. B. Kal, D. G. de Rooij (2001) Role for c-Abl and p73 in the radiation response of male germ cells. Oncogene 20:4298-4304.
-
(2001)
Oncogene
, vol.20
, pp. 4298-4304
-
-
Hamer, G.1
Gademan, I.S.2
Kal, H.B.3
De Rooij, D.G.4
-
28
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., R. A. Weinberg (2000) The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell.
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
29
-
-
63749105896
-
Mechanism of TGF-β signaling to growth arrest, apoptosis, and epithelialmesenchymal transition
-
Heldin, C. H., M. Landstrom, A. Moustakas (2009) Mechanism of TGF-β signaling to growth arrest, apoptosis, and epithelialmesenchymal transition. Curr Opin Cell Biol 21:166-176.
-
(2009)
Curr. Opin. Cell. Biol.
, vol.21
, pp. 166-176
-
-
Heldin, C.H.1
Landstrom, M.2
Moustakas, A.3
-
30
-
-
4344612243
-
NF-kB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
-
Huber, M. A., N. Azoitei, B. Baumann, S. Grunert, A. Sommer, H. Pehamberger, N. Kraut, H. Beug, T. Wirth (2004) NF-kB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest 114:569-581.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 569-581
-
-
Huber, M.A.1
Azoitei, N.2
Baumann, B.3
Grunert, S.4
Sommer, A.5
Pehamberger, H.6
Kraut, N.7
Beug, H.8
Wirth, T.9
-
31
-
-
34848826864
-
Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression
-
Hugo, H, M. L. Ackland, T. Blick, M. G Lawrence, J. A. Clements, E. D. Williams, EW. Thompson (2007) Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression. J Cell Physiol 213:374-383.
-
(2007)
J. Cell. Physiol.
, vol.213
, pp. 374-383
-
-
Hugo, H.1
Ackland, M.L.2
Blick, T.3
Lawrence, M.G.4
Clements, J.A.5
Williams, E.D.6
Thompson, E.W.7
-
32
-
-
34547667231
-
Treatment for chronic myelogenous leukemia: The long road to imatinib
-
Hunter, T. (2007) Treatment for chronic myelogenous leukemia: the long road to imatinib. J Clin Invest 117:2036-2043.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2036-2043
-
-
Hunter, T.1
-
33
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal, A., R. Siegel, E. Ward, Y. Hao, J. Xu, M. J. Thun (2009) Cancer statistics, 2009. CA Cancer J Clin 59:225-249.
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
34
-
-
0038505214
-
Cytoplasmic c-Abl provides a molecular 'Rheostat' controlling carcinoma cell survival and invasion
-
Kain, K. H., S. Gooch, R. L. Klemke (2003) Cytoplasmic c-Abl provides a molecular 'Rheostat' controlling carcinoma cell survival and invasion. Oncogene 22:6071-6080.
-
(2003)
Oncogene
, vol.22
, pp. 6071-6080
-
-
Kain, K.H.1
Gooch, S.2
Klemke, R.L.3
-
35
-
-
0035844250
-
Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes
-
Kain, K. H., R. L. Klemke (2001) Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes. J Biol Chem 276:16185-16192.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16185-16192
-
-
Kain, K.H.1
Klemke, R.L.2
-
36
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri, R., R. A. Weinberg (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420-1428.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
37
-
-
34547587877
-
Cell size and invasion in TGF-β-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway
-
Lamouille, S., R. Derynck (2007) Cell size and invasion in TGF-β-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway. J Cell Biol 178:437-451.
-
(2007)
J. Cell. Biol.
, vol.178
, pp. 437-451
-
-
Lamouille, S.1
Derynck, R.2
-
38
-
-
78650510746
-
Emergence of the phosphoinositide 3-kinase-akt-mammalian target of rapamycin axis in transforming growth factor-β-induced epithelial- mesenchymal transition
-
Lamouille, S., R. Derynck (2011) Emergence of the phosphoinositide 3-kinase-akt-mammalian target of rapamycin axis in transforming growth factor-β-induced epithelial-mesenchymal transition. Cells Tissues Organs 193:8-22.
-
(2011)
Cells Tissues Organs
, vol.193
, pp. 8-22
-
-
Lamouille, S.1
Derynck, R.2
-
39
-
-
57349137178
-
Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-β in mammary epithelial cells via a MMP-dependent mechanism
-
Lee, Y. H., A. R. Albig, M. Regner, B. J. Schiemann, W. P. Schiemann (2008) Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-β in mammary epithelial cells via a MMP-dependent mechanism. Carcinogenesis 29:2243-2251.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2243-2251
-
-
Lee, Y.H.1
Albig, A.R.2
Regner, M.3
Schiemann, B.J.4
Schiemann, W.P.5
-
40
-
-
0030459950
-
Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport
-
Lewis, J. M., R. Baskaran, S. Taagepera, M. A. Schwartz, JY. Wang (1996) Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport. Proc Natl Acad Sci USA 93:15174-15179.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15174-15179
-
-
Lewis, J.M.1
Baskaran, R.2
Taagepera, S.3
Schwartz, M.A.4
Wang, J.Y.5
-
41
-
-
52049121297
-
DNA mismatch repair-dependent activation of c-Abl/p73α/GADD45alpha- mediated apoptosis
-
Li, L. S., J. C Morales, A. Hwang, M. W. Wagner, D. A. Boothman (2008) DNA mismatch repair-dependent activation of c-Abl/p73α/GADD45alpha- mediated apoptosis. J Biol Chem 283:21394-21403.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 21394-21403
-
-
Li, L.S.1
Morales, J.C.2
Hwang, A.3
Wagner, M.W.4
Boothman, D.A.5
-
42
-
-
34547938724
-
A phase I trial of docetaxel/estramustine/imatinib in patients with hormone-refractory prostate cancer
-
Lin, A. M., B. I. Rini, M. K. Derynck, V. Weinberg, M. Park, C. J. Ryan, J. E. Rosenberg, G. Bubley, E. J. Small (2007a) A phase I trial of docetaxel/estramustine/imatinib in patients with hormone-refractory prostate cancer. Clin Genitourin Cancer 5:323-328.
-
(2007)
Clin. Genitourin Cancer
, vol.5
, pp. 323-328
-
-
Lin, A.M.1
Rini, B.I.2
Derynck, M.K.3
Weinberg, V.4
Park, M.5
Ryan, C.J.6
Rosenberg, J.E.7
Bubley, G.8
Small, E.J.9
-
43
-
-
33748576904
-
A phase II trial of imatinib mesylate in patients with biochemical relapse of prostate cancer after definitive local therapy
-
Lin, A. M., B. I. Rini, V. Weinberg, K. Fong, C. J. Ryan, J. E. Rosenberg, L. Fong, E. J. Small (2006) A phase II trial of imatinib mesylate in patients with biochemical relapse of prostate cancer after definitive local therapy. BJU Int 98:763-769.
-
(2006)
BJU Int.
, vol.98
, pp. 763-769
-
-
Lin, A.M.1
Rini, B.I.2
Weinberg, V.3
Fong, K.4
Ryan, C.J.5
Rosenberg, J.E.6
Fong, L.7
Small, E.J.8
-
44
-
-
47949106116
-
Activated c-Abl tyrosine kinase in malignant solid tumors
-
Lin, J., R. Arlinghaus (2008) Activated c-Abl tyrosine kinase in malignant solid tumors. Oncogene 27:4385-4391.
-
(2008)
Oncogene
, vol.27
, pp. 4385-4391
-
-
Lin, J.1
Arlinghaus, R.2
-
45
-
-
35548969446
-
Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: Inhibition of c-Abl by the tumor suppressor gene product Fus1
-
Lin, J., T. Sun, L. Ji, W. Deng, J. Roth, J. Minna, R. Arlinghaus (2007b) Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1. Oncogene 26:6989-6996.
-
(2007)
Oncogene
, vol.26
, pp. 6989-6996
-
-
Lin, J.1
Sun, T.2
Ji, L.3
Deng, W.4
Roth, J.5
Minna, J.6
Arlinghaus, R.7
-
46
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani, S. A., W. Guo, M. J. Liao, E. N. Eaton, A. Ayyanan, AY. Zhou, M. Brooks, F. Reinhard, C. C. Zhang, M. Shipitsin, L. L. Campbell, K. Polyak, C. Brisken, J. Yang, R. A. Weinberg (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133:704-715.
-
(2008)
Cell.
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
47
-
-
47549090432
-
TGF-β in cancer
-
Massague, J. (2008) TGF-β in Cancer. Cell 134:215-230.
-
(2008)
Cell.
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
48
-
-
78650511931
-
Smaddening complexity: The role of Smad3 in epithelial-myofibroblast transition
-
Masszi, A., A. Kapus (2011) Smaddening complexity: The role of Smad3 in epithelial-myofibroblast transition. Cells Tissues Organs 193:41-52.
-
(2011)
Cells Tissues Organs
, vol.193
, pp. 41-52
-
-
Masszi, A.1
Kapus, A.2
-
49
-
-
0034951384
-
STI571: Targeting BCR-ABL as therapy for CML
-
Mauro, M. J., B. J. Druker (2001) STI571: targeting BCR-ABL as therapy for CML. Oncologist 6:233-238.
-
(2001)
Oncologist
, vol.6
, pp. 233-238
-
-
Mauro, M.J.1
Druker, B.J.2
-
50
-
-
0036139993
-
STI571: A paradigm of new agents for cancer therapeutics
-
Mauro, M. J., M. O'Dwyer, M. C. Heinrich, B. J. Druker (2002) STI571: a paradigm of new agents for cancer therapeutics. J Clin Oncol 20:325-334.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 325-334
-
-
Mauro, M.J.1
O'Dwyer, M.2
Heinrich, M.C.3
Druker, B.J.4
-
51
-
-
0344255674
-
Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas
-
Miller, C. T., G. Chen, T. G. Gharib, H. Wang, D. G Thomas, D. E. Misek, T. J. Giordano, J. Yee, M. B. Orringer, S. M. Hanash, D. G. Beer (2003) Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas. Oncogene 22:7950-7957.
-
(2003)
Oncogene
, vol.22
, pp. 7950-7957
-
-
Miller, C.T.1
Chen, G.2
Gharib, T.G.3
Wang, H.4
Thomas, D.G.5
Misek, D.E.6
Giordano, T.J.7
Yee, J.8
Orringer, M.B.9
Hanash, S.M.10
Beer, D.G.11
-
52
-
-
21044450946
-
A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer
-
Modi, S., A. D. Seidman, M. Dickler, M. Moasser, G. D'Andrea, M. E. Moynahan, J. Menell, K. S. Panageas, L. K. Tan, L. Norton, C. A. Hudis (2005) A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer. Breast Cancer Res Treat 90:157-163.
-
(2005)
Breast Cancer Res. Treat
, vol.90
, pp. 157-163
-
-
Modi, S.1
Seidman, A.D.2
Dickler, M.3
Moasser, M.4
D'Andrea, G.5
Moynahan, M.E.6
Menell, J.7
Panageas, K.S.8
Tan, L.K.9
Norton, L.10
Hudis, C.A.11
-
53
-
-
56049089380
-
Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-β through a PGE2-dependent mechanisms
-
Neil, J. R., K. M. Johnson, R. A. Nemenoff, W. P. Schiemann (2008) Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-β through a PGE2-dependent mechanisms. Carcinogenesis 29:2227-2235.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2227-2235
-
-
Neil, J.R.1
Johnson, K.M.2
Nemenoff, R.A.3
Schiemann, W.P.4
-
54
-
-
40449092814
-
Altered TAB1: IkB kinase interaction promotes TGF-β-mediated NF-kB activation during breast cancer progression
-
Neil, J. R., W. P. Schiemann (2008) Altered TAB1: IkB kinase interaction promotes TGF-β-mediated NF-kB activation during breast cancer progression. Cancer Res 68:1462-1470.
-
(2008)
Cancer Res.
, vol.68
, pp. 1462-1470
-
-
Neil, J.R.1
Schiemann, W.P.2
-
55
-
-
69249126664
-
X-linked inhibitor of apoptosis protein and its E3 ligase activity promote TGF-β-mediated NF-kB activation during breast cancer progression
-
Neil, J. R., M. Tian, W. P. Schiemann (2009) X-linked inhibitor of apoptosis protein and its E3 ligase activity promote TGF-β-mediated NF-kB activation during breast cancer progression. J Biol Chem 284:21209-21217.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 21209-21217
-
-
Neil, J.R.1
Tian, M.2
Schiemann, W.P.3
-
56
-
-
33746646032
-
The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway
-
Noren, N. K., G. Foos, C. A. Hauser, E. B. Pasquale (2006) The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway. Nat Cell Biol 8:815-825.
-
(2006)
Nat. Cell. Biol.
, vol.8
, pp. 815-825
-
-
Noren, N.K.1
Foos, G.2
Hauser, C.A.3
Pasquale, E.B.4
-
57
-
-
0029662049
-
1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev 10:2462-2477
-
(1996)
Genes Dev.
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Peli, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
Reichmann, E.6
-
58
-
-
14844364701
-
Regulation of the polarity protein Par6 by TGF-β receptors controls epithelial cell plasticity
-
Ozdamar, B., R. Bose, M. Barrios-Rodiles, H. R. Wang, Y. Zhang, J. L. Wrana (2005) Regulation of the polarity protein Par6 by TGF-β receptors controls epithelial cell plasticity. Science 307:1603-1609.
-
(2005)
Science
, vol.307
, pp. 1603-1609
-
-
Ozdamar, B.1
Bose, R.2
Barrios-Rodiles, M.3
Wang, H.R.4
Zhang, Y.5
Wrana, J.L.6
-
59
-
-
33845334175
-
Actions of TGF-β as tumor suppressor and pro-metastatic factor in human cancer
-
Pardali, K., A. Moustakas (2007) Actions of TGF-β as tumor suppressor and pro-metastatic factor in human cancer. Biochim Biophys Acta 1775:21-62.
-
(2007)
Biochim Biophys. Acta
, vol.1775
, pp. 21-62
-
-
Pardali, K.1
Moustakas, A.2
-
60
-
-
0029924347
-
Nuclear tyrosine kinases: From Abl to WEE1
-
Pendergast, A. M. (1996) Nuclear tyrosine kinases: from Abl to WEE1. Curr Opin Cell Biol 8:174-181.
-
(1996)
Curr. Opin. Cell. Biol.
, vol.8
, pp. 174-181
-
-
Pendergast, A.M.1
-
61
-
-
0036391801
-
The Abl family kinases: Mechanisms of regulation and signaling
-
Pendergast, A. M. (2002) The Abl family kinases: mechanisms of regulation and signaling. Adv Cancer Res 85:51-100.
-
(2002)
Adv. Cancer Res.
, vol.85
, pp. 51-100
-
-
Pendergast, A.M.1
-
62
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou, C.M., T. Sorlie, M. B. Eisen, M. van de Rijn, S. S. Jeffrey, C. A. Rees, J. R. Pollack, D. T Ross, H. Johnsen, L. A. Akslen, O. Fluge, A. Pergamenschikov, C. Williams, S. X. Zhu, P. E. Lonning, A. L. Borresen-Dale, P. O. Brown, D. Botstein (2000) Molecular portraits of human breast tumours. Nature 406:747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
Van De Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
Pollack, J.R.7
Ross, D.T.8
Johnsen, H.9
Akslen, L.A.10
Fluge, O.11
Pergamenschikov, A.12
Williams, C.13
Zhu, S.X.14
Lonning, P.E.15
Borresen-Dale, A.L.16
Brown, P.O.17
Botstein, D.18
-
63
-
-
0033568349
-
C-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF
-
Plattner, R., L. Kadlec, K. A. DeMali, A. Kazlauskas, A. M. Pendergast (1999) c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF. Genes Dev 13:2400-2411.
-
(1999)
Genes Dev.
, vol.13
, pp. 2400-2411
-
-
Plattner, R.1
Kadlec, L.2
DeMali, K.A.3
Kazlauskas, A.4
Pendergast, A.M.5
-
64
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak, K., R. A. Weinberg (2009) Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9:265-273.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
65
-
-
34248571400
-
Targeted TGF-β chemotherapies: Friend or foe in treating human malignancies?
-
Schiemann, W. P. (2007) Targeted TGF-β chemotherapies: friend or foe in treating human malignancies? Expert Rev Anticancer Ther 7:609-611.
-
(2007)
Expert Rev. Anticancer Ther.
, vol.7
, pp. 609-611
-
-
Schiemann, W.P.1
-
66
-
-
0034064630
-
C-Abl: Activation and nuclear targets
-
Shaul, Y. (2000) c-Abl: activation and nuclear targets. Cell Death Differ 7:10-16.
-
(2000)
Cell. Death Differ
, vol.7
, pp. 10-16
-
-
Shaul, Y.1
-
67
-
-
33847419142
-
Molecular definition of breast tumor heterogeneity
-
Shipitsin, M., L. L. Campbell, P. Argani, S. Weremowicz, N. Bloushtain-Qimron, J. Yao, T Nikolskaya, T. Serebryiskaya, R. Beroukhim, M. Hu, M. K. Halushka, S. Sukumar, L. M. Parker, K. S. Anderson, L. N. Harris, J. E. Garber, A. L. Richardson, S. J. Schnitt, Y. Nikolsky, R. S. Gelman, K. Polyak (2007) Molecular definition of breast tumor heterogeneity. Cancer Cell 11:259-273.
-
(2007)
Cancer Cell.
, vol.11
, pp. 259-273
-
-
Shipitsin, M.1
Campbell, L.L.2
Argani, P.3
Weremowicz, S.4
Bloushtain-Qimron, N.5
Yao, J.T.N.6
Serebryiskaya, T.7
Beroukhim, R.8
Hu, M.9
Halushka, M.K.10
Sukumar, S.11
Parker, L.M.12
Anderson, K.S.13
Harris, L.N.14
Garber, J.E.15
Richardson, A.L.16
Schnitt, S.J.17
Nikolsky, Y.18
Gelman, R.S.19
Polyak, K.20
more..
-
68
-
-
36148956209
-
The tyrosine kinase Abl is required for Src-transforming activity in mouse fibroblasts and human breast cancer cells
-
Sirvent, A., A. Boureux, V. Simon, C. Leroy, S. Roche (2007) The tyrosine kinase Abl is required for Src-transforming activity in mouse fibroblasts and human breast cancer cells. Oncogene 26:7313-7323.
-
(2007)
Oncogene
, vol.26
, pp. 7313-7323
-
-
Sirvent, A.1
Boureux, A.2
Simon, V.3
Leroy, C.4
Roche, S.5
-
69
-
-
33644840524
-
The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by TGF-β
-
Sokol, J. P., J. R. Neil, B. J. Schiemann, W. P. Schiemann (2005) The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by TGF-β. Breast Cancer Res 7: R844-R853.
-
(2005)
Breast Cancer Res.
, vol.7
-
-
Sokol, J.P.1
Neil, J.R.2
Schiemann, B.J.3
Schiemann, W.P.4
-
70
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie, T., CM. Perou, R. Tibshirani, T. Aas, S. Geisler, H. Johnsen, T. Hastie, M. B. Eisen, M. van de Rijn, S. S. Jeffrey, T. Thorsen, H. Quist, J. C. Matese, P. O. Brown, D. Botstein, P. Eystein Lonning, A. L. Borresen-Dale (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98:10869-10874.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
Hastie, T.7
Eisen, M.B.8
Van De Rijn, M.9
Jeffrey, S.S.10
Thorsen, T.11
Quist, H.12
Matese, J.C.13
Brown, P.O.14
Botstein, D.15
Lonning, P.E.16
Borresen-Dale, A.L.17
-
71
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sorlie, T., R. Tibshirani, J. Parker, T. Hastie, J. S. Marron, A. Nobel, S. Deng, H. Johnsen, R. Pesich, S. Geisler, J. Demeter, CM. Perou, P. E. Lonning, P. O. Brown, A. L. Borresen-Dale, D. Botstein (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 100:8418-8423.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
Hastie, T.4
Marron, J.S.5
Nobel, A.6
Deng, S.7
Johnsen, H.8
Pesich, R.9
Geisler, S.10
Demeter, J.11
Perou, C.M.12
Lonning, P.E.13
Brown, P.O.14
Borresen-Dale, A.L.15
Botstein, D.16
-
72
-
-
47249123315
-
Imatinib mesylate for the treatment of chronic myeloid leukemia
-
Soverini, S., G. Martinelli, I. Iacobucci, M. Baccarani (2008) Imatinib mesylate for the treatment of chronic myeloid leukemia. Expert Rev Anticancer Ther 8:853-864.
-
(2008)
Expert Rev. Anticancer Ther.
, vol.8
, pp. 853-864
-
-
Soverini, S.1
Martinelli, G.2
Iacobucci, I.3
Baccarani, M.4
-
73
-
-
33745251071
-
Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells
-
Srinivasan, D., R. Plattner (2006) Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells. Cancer Res 66:5648-5655.
-
(2006)
Cancer Res.
, vol.66
, pp. 5648-5655
-
-
Srinivasan, D.1
Plattner, R.2
-
74
-
-
39149121810
-
Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival
-
Srinivasan, D., J. T. Sims, R. Plattner (2008) Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival. Oncogene 27:1095-1105.
-
(2008)
Oncogene
, vol.27
, pp. 1095-1105
-
-
Srinivasan, D.1
Sims, J.T.2
Plattner, R.3
-
75
-
-
38449106371
-
Regulation of cellular transformation by oncogenic and normal Abl kinases
-
Suzuki, J., T. Shishido (2007) Regulation of cellular transformation by oncogenic and normal Abl kinases. J Biochem 141:453-458.
-
(2007)
J. Biochem.
, vol.141
, pp. 453-458
-
-
Suzuki, J.1
Shishido, T.2
-
76
-
-
0032560516
-
Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase
-
Taagepera, S., D. McDonald, J. E. Loeb, L. L. Whitaker, A. K. McElroy, J. Y. Wang, T. J. Hope (1998) Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase. Proc Natl Acad Sci USA 95:7457-7462.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7457-7462
-
-
Taagepera, S.1
McDonald, D.2
Loeb, J.E.3
Whitaker, L.L.4
McElroy, A.K.5
Wang, J.Y.6
Hope, T.J.7
-
77
-
-
34548706039
-
TGF-β can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model
-
Tang, B., N. Yoo, M. Vu, M. Mamura, J. S. Nam, A. Ooshima, Z. Du, P. Y. Desprez, M. R. Anver, A. M. Michalowska, J. Shih, W. T. Parks, L. M. Wakefield (2007) TGF-β can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model. Cancer Res 67:8643-8652.
-
(2007)
Cancer Res.
, vol.67
, pp. 8643-8652
-
-
Tang, B.1
Yoo, N.2
Vu, M.3
Mamura, M.4
Nam, J.S.5
Ooshima, A.6
Du, Z.7
Desprez, P.Y.8
Anver, M.R.9
Michalowska, A.M.10
Shih, J.11
Parks, W.T.12
Wakefield, L.M.13
-
78
-
-
0344845003
-
Epithelial-mesenchymal transitions in development and pathologies
-
Thiery, J. P. (2003) Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 15:740-746.
-
(2003)
Curr. Opin. Cell. Biol.
, vol.15
, pp. 740-746
-
-
Thiery, J.P.1
-
79
-
-
77951649508
-
PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-β signaling during mammary tumorigenesis
-
Tian, M., W. P. Schiemann (2009a) PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-β signaling during mammary tumorigenesis. FASEB J 24:1105-1116.
-
(2009)
FASEB J.
, vol.24
, pp. 1105-1116
-
-
Tian, M.1
Schiemann, W.P.2
-
80
-
-
66349135076
-
The TGF-β paradox in human cancer: An update
-
Tian, M., W. P. Schiemann (2009b) The TGF-β paradox in human cancer: an update. Future Oncol 5:259-271.
-
(2009)
Future Oncol.
, vol.5
, pp. 259-271
-
-
Tian, M.1
Schiemann, W.P.2
-
81
-
-
0042337427
-
Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl
-
Truong, T., G. Sun, M. Doorly, J. Y. Wang, M. A. Schwartz (2003) Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl. Proc Natl Acad Sci USA 100:10281-10286.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10281-10286
-
-
Truong, T.1
Sun, G.2
Doorly, M.3
Wang, J.Y.4
Schwartz, M.A.5
-
82
-
-
16344378397
-
TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelialmesenchymal cell transition
-
Valcourt, U, M. Kowanetz, H. Niimi, C. H. Heldin, A. Moustakas (2005) TGF-β and the Smad signaling pathway support transcriptomic reprogramming during epithelialmesenchymal cell transition. Mol Biol Cell 16:1987-2002.
-
(2005)
Mol. Biol. Cell.
, vol.16
, pp. 1987-2002
-
-
Valcourt, U.1
Kowanetz, M.2
Niimi, H.3
Heldin, C.H.4
Moustakas, A.5
-
83
-
-
0035122485
-
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase
-
Vigneri, P., J. Y. Wang (2001) Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nat Med 7:228-234.
-
(2001)
Nat. Med.
, vol.7
, pp. 228-234
-
-
Vigneri, P.1
Wang, J.Y.2
-
84
-
-
52049122158
-
Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses
-
Wagner, M. W., L. S. Li, J. C. Morales, C. L. Galindo, H. R. Garner, W. G Bornmann, D. A. Boothman (2008) Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses. J Biol Chem 283:21382-21393.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 21382-21393
-
-
Wagner, M.W.1
Li, L.S.2
Morales, J.C.3
Galindo, C.L.4
Garner, H.R.5
Bornmann, W.G.6
Boothman, D.A.7
-
85
-
-
33746635215
-
Eph tumour suppression: The dark side of Gleevec
-
Wang, J. Y. (2006) Eph tumour suppression: the dark side of Gleevec. Nat Cell Biol 8:785-786.
-
(2006)
Nat. Cell. Biol.
, vol.8
, pp. 785-786
-
-
Wang, J.Y.1
-
86
-
-
0021265841
-
The mouse c-Abl locus: Molecular cloning and characterization
-
Wang, J. Y., F. Ledley, S. Goff, R. Lee, Y. Groner, D. Baltimore (1984) The mouse c-Abl locus: molecular cloning and characterization. Cell 36:349-356.
-
(1984)
Cell.
, vol.36
, pp. 349-356
-
-
Wang, J.Y.1
Ledley, F.2
Goff, S.3
Lee, R.4
Groner, Y.5
Baltimore, D.6
-
87
-
-
11244292291
-
Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo
-
Wang, S., M. C. Wilkes, E. B. Leof, R. Hirschberg (2005) Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo. FASEB J 19:1-11.
-
(2005)
FASEB J.
, vol.19
, pp. 1-11
-
-
Wang, S.1
Wilkes, M.C.2
Leof, E.B.3
Hirschberg, R.4
-
88
-
-
0029879676
-
The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products
-
Wen, S. T., P. K. Jackson, R. A. Van Etten (1996) The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products. EMBO J 15:1583-1595.
-
(1996)
EMBO J.
, vol.15
, pp. 1583-1595
-
-
Wen, S.T.1
Jackson, P.K.2
Van Etten, R.A.3
-
89
-
-
75649088874
-
Mechanisms of the epithelial-mesenchymal transition by TGF-β
-
Wendt, M. K., T. M. Allington, W. P. Schiemann (2009a) Mechanisms of the epithelial-mesenchymal transition by TGF-β. Future Oncol 5:1145-1168.
-
(2009)
Future Oncol.
, vol.5
, pp. 1145-1168
-
-
Wendt, M.K.1
Allington, T.M.2
Schiemann, W.P.3
-
90
-
-
71749100944
-
Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-β signaling and metastasis
-
Wendt, M. K., W. P. Schiemann (2009) Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-β signaling and metastasis. Breast Cancer Res 11: R68.
-
(2009)
Breast Cancer Res.
, vol.11
-
-
Wendt, M.K.1
Schiemann, W.P.2
-
91
-
-
71749099201
-
P130Cas is required for mammary tumor growth and TGF-β-mediated metastasis through regulation of Smad2/3 activity
-
Wendt, M. K., J. A. Smith, W. P. Schiemann (2009b) p130Cas is required for mammary tumor growth and TGF-β-mediated metastasis through regulation of Smad2/3 activity. J Biol Chem 284:34145-34156.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 34145-34156
-
-
Wendt, M.K.1
Smith, J.A.2
Schiemann, W.P.3
-
92
-
-
33748760321
-
TGF-β activation of c-Abl is independent of receptor internalization and regulated by phosphatidylinositol 3-kinase and PAK2 in mesenchymal cultures
-
Wilkes, M. C., E. B. Leof (2006) TGF-β activation of c-Abl is independent of receptor internalization and regulated by phosphatidylinositol 3-kinase and PAK2 in mesenchymal cultures. J Biol Chem 281:27846-27854.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 27846-27854
-
-
Wilkes, M.C.1
Leof, E.B.2
-
93
-
-
0035920195
-
Inhibition of c-Abl tyrosine kinase activity by filamentous actin
-
Woodring, P. J., T. Hunter, J. Y. Wang (2001) Inhibition of c-Abl tyrosine kinase activity by filamentous actin. J Biol Chem 276:27104-27110.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27104-27110
-
-
Woodring, P.J.1
Hunter, T.2
Wang, J.Y.3
-
94
-
-
0037018155
-
Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension
-
Woodring, P. J., E. D. Litwack, D. D. O'Leary, GR. Lucero, J. Y. Wang, T. Hunter (2002) Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension. J Cell Biol 156:879-892.
-
(2002)
J. Cell. Biol.
, vol.156
, pp. 879-892
-
-
Woodring, P.J.1
Litwack, E.D.2
O'Leary, D.D.3
Lucero, G.R.4
Wang, J.Y.5
Hunter, T.6
-
95
-
-
2542478972
-
C-Abl phosphorylates Dok1 to promote filopodia during cell spreading
-
Woodring, P. J., J. Meisenhelder, S. A. Johnson, G. L. Zhou, J. Field, K. Shah, F. Bladt, T. Pawson, M. Niki, P. P. Pandolfi, J. Y. Wang, T. Hunter (2004) c-Abl phosphorylates Dok1 to promote filopodia during cell spreading. J Cell Biol 165:493-503.
-
(2004)
J. Cell. Biol.
, vol.165
, pp. 493-503
-
-
Woodring, P.J.1
Meisenhelder, J.2
Johnson, S.A.3
Zhou, G.L.4
Field, J.5
Shah, K.6
Bladt, F.7
Pawson, T.8
Niki, M.9
Pandolfi, P.P.10
Wang, J.Y.11
Hunter, T.12
-
97
-
-
59449090107
-
TGF-β-induced epithelial to mesenchymal transition
-
Xu, J., S. Lamouille, R. Derynck (2009) TGF-β-induced epithelial to mesenchymal transition. Cell Res 19:156-172.
-
(2009)
Cell. Res.
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
98
-
-
37349100945
-
Abrogation of TGF-β signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis
-
Yang, L., J. Huang, X. Ren, A. E. Gorska, A. Chytil, M. Aakre, D. P. Carbone, L. M. Matrisian, A. Richmond, PC. Lin, H. L. Moses (2008) Abrogation of TGF-β signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell 13:23-35.
-
(2008)
Cancer Cell.
, vol.13
, pp. 23-35
-
-
Yang, L.1
Huang, J.2
Ren, X.3
Gorska, A.E.4
Chytil, A.5
Aakre, M.6
Carbone, D.P.7
Matrisian, L.M.8
Richmond, A.9
Lin, P.C.10
Moses, H.L.11
-
99
-
-
0033600235
-
P73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
-
Yuan, Z. M., H. Shioya, T. Ishiko, X. Sun, J. Gu, Y. Y. Huang, H. Lu, S. Kharbanda, R. Weichselbaum, D. Kufe (1999) p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature 399:814-817.
-
(1999)
Nature
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
Sun, X.4
Gu, J.5
Huang, Y.Y.6
Lu, H.7
Kharbanda, S.8
Weichselbaum, R.9
Kufe, D.10
-
100
-
-
40549133440
-
Abl tyrosine kinases modulate cadherin-dependent adhesion upstream and downstream of Rho family GTPases
-
Zandy, N. L., A. M. Pendergast (2008) Abl tyrosine kinases modulate cadherin-dependent adhesion upstream and downstream of Rho family GTPases. Cell Cycle 7:444-448.
-
(2008)
Cell. Cycle
, vol.7
, pp. 444-448
-
-
Zandy, N.L.1
Pendergast, A.M.2
-
101
-
-
36749011318
-
Abl tyrosine kinases regulate cell-cell adhesion through Rho GTPases
-
Zandy, N. L., M. Playford, A. M. Pendergast (2007) Abl tyrosine kinases regulate cell-cell adhesion through Rho GTPases. Proc Natl Acad Sci USA 104:17686-17691.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 17686-17691
-
-
Zandy, N.L.1
Playford, M.2
Pendergast, A.M.3
-
102
-
-
2142818004
-
Death by Abl: A matter of location
-
Zhu, J., J. Y. Wang (2004) Death by Abl: a matter of location. Curr Top Dev Biol 59:165-192.
-
(2004)
Curr. Top Dev. Biol.
, vol.59
, pp. 165-192
-
-
Zhu, J.1
Wang, J.Y.2
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