Convenient methods for the synthesis of d4, d2 and d6 isotopomers of 4-(4-fluorobenzyl)piperidine

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 48, Issue 6, 2005, Pages 421-427

  Proszenyák, Ágnes ^a   Ágai, Béla ^a   Tárkányi, Gábor ^b   Vida, László ^a   Faigl, Ferenc ^a  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^b GEDEON RICHTER LTD   (Hungary)

Author keywords

Benzylpiperidines; Catalytic hydrogenation; Deuterium labelled compounds; Grignard reaction; Palladium on carbon

Indexed keywords

CARBON; HYDROGENATION; SYNTHESIS (CHEMICAL);

4-BROMOBENZENE; BENZYLPIPERIDINE; CARBON CATALYSTS; CATALYTIC HYDROGENATION; DEOXYGENATIONS; DEUTERIUM-LABELED COMPOUND; GRIGNARD REACTION; H-D EXCHANGE; ISOTOPOMERS; PALLADIUM ON CARBONS;

PALLADIUM;

4 (4 FLUOROBENZYL)PIPERIDINE; ALDEHYDE; BESONPRODIL; BROMOBENZENE; CARBON; CI 1041; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PALLADIUM; PIPERIDINE DERIVATIVE; RO 256981; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DEOXYGENATION; DRUG STRUCTURE; DRUG SYNTHESIS; GAS CHROMATOGRAPHY; GRIGNARD REACTION; HYPERALGESIA; MASS SPECTROMETRY; NEUROPROTECTION; PARKINSON DISEASE; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 19544380406     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.936     Document Type: Article

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