Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic β cells

Journal of Biological Chemistry

Volumn 285, Issue 52, 2010, Pages 41044-41050

  Xuan, Shouhong ^a   Szabolcs, Matthias ^a   Cinti, Francesca ^a   Perincheri, Suhdir ^a   Accili, Domenico ^b   Efstratiadis, Argiris ^a,c  

^a Department of Genetics and Development ^*  (United States)

^b Department of Pathology ^*  (United States)

^c BIOMEDICAL RESEARCH FOUNDATION   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITIVITY; CELL FUNCTIONS; CELL MASS; CELL REPLICATION; DOUBLE MUTANTS; GENETIC ANALYSIS; GLUCOSE TOLERANCE; IGF1 RECEPTOR; INSULIN RECEPTOR SUBSTRATE-1; INSULIN RECEPTORS; INSULIN SECRETION; INSULIN-LIKE GROWTH FACTOR RECEPTORS; KNOCK OUTS; RECEPTOR TYROSINE KINASE; SIGNALING CASCADES; SINGLE MUTANT;

ABLATION; AMINO ACIDS; CELL PROLIFERATION; GLUCOSE; MEDICAL PROBLEMS; SIGNALING;

INSULIN;

INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; GENE INACTIVATION; GENETIC ANALYSIS; GLUCOSE TOLERANCE; HYPERINSULINEMIA; INSULIN RELEASE; MALE; MOUSE; MOUSE MUTANT; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; CELL PROLIFERATION; DIABETES MELLITUS; GLUCOSE; HUMANS; HYPERINSULINISM; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-SECRETING CELLS; MICE; MICE, KNOCKOUT; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

MUS;

EID: 78650359646     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.144790     Document Type: Article

References (48)

1. Accili, D. (2004) Diabetes 53, 1633-1642
2. Weyer, C., Bogardus, C., Mott, D. M., and Pratley, R. E. (1999) J. Clin. Invest. 104, 787-794
3. Levy, J., Atkinson, A. B., Bell, P. M., McCance, D. R., and Hadden, D. R. (1998) Diabet. Med. 15, 290-296
4. Kahn, S. E. (2003) Diabetologia 46, 3-19
5. Monnier, L., Colette, C., Dunseath, G. J., and Owens, D. R. (2007) Diabetes Care 30, 263-269
6. O'Rahilly, S., Turner, R. C., and Matthews, D. R. (1988) N. Engl. J. Med. 318, 1225-1230
7. Polonsky, K. S., Given, B. D., Hirsch, L. J., Tillil, H., Shapiro, E. T., Beebe, C., Frank, B. H., Galloway, J. A., and Van Cauter, E. (1988) N. Engl. J. Med. 318, 1231-1239
8. Rahier, J., Guiot, Y., Goebbels, R. M., Sempoux, C., and Henquin, J. C. (2008) Diabetes Obes. Metab. 10, Suppl. 4, 32-42
9. Bell, G. I., and Polonsky, K. S. (2001) Nature 414, 788-791
10. Leahy, J. L., Bonner-Weir, S., and Weir, G. C. (1992) Diabetes Care. 15, 442-455
11. Ferrannini, E. (1998) Endocrine Rev. 19, 477-490
12. Butler, A. E., Janson, J., Bonner-Weir, S., Ritzel, R., Rizza, R. A., and Butler, P. C. (2003) Diabetes 52, 102-110
13. Teta, M., Long, S. Y., Wartschow, L. M., Rankin, M. M., and Kushner, J. A. (2005) Diabetes 54, 2557-2567
14. Kulkarni, R. N., Holzenberger, M., Shih, D. Q., Ozcan, U., Stoffel, M., Magnuson, M. A., and Kahn, C. R. (2002) Nat. Genet. 31, 111-115
15. Xuan, S., Kitamura, T., Nakae, J., Politi, K., Kido, Y., Fisher, P. E., Morroni, M., Cinti, S., White, M. F., Herrera, P. L., Accili, D., and Efstratiadis, A. (2002) J. Clin. Invest. 110, 1011-1019
16. Araki, E., Lipes, M. A., Patti, M. E., Brüning, J. C., Haag, B., 3rd, Johnson, R. S., and Kahn, C. R. (1994) Nature 372, 186-190
17. Tamemoto, H., Kadowaki, T., Tobe, K., Yagi, T., Sakura, H., Hayakawa, T., Terauchi, Y., Ueki, K., Kaburagi, Y., Satoh, S., Sekihara, H., Yoshioka, S., Horikoshi, H., Furuta, Y., Ikawa, Y., Kasuga, M., Yazaki, Y., and Aizawa, S. (1994) Nature 372, 182-186
18. Withers, D. J., Sanchez-Gutierrez, J., Towery, H., Burks, D. J., Ren, J. M., Previs, S., Zhang, Y., Bernal, D., Pons, S., Shulman, G. I., Bonner-Weir, S., and White, M. F. (1998) Nature 391, 900-904
19. Kubota, N., Tobe, K., Terauchi, Y., Eto, K., Yamauchi, T., Suzuki, R., Tsubamoto, Y., Komeda, K., Nakano, R., Miki, H., Satoh, S., Sekihara, H., Sciacchitano, S., Lesniak, M., Aizawa, S., Nagai, R., Kimura, S., Akanuma, Y., Taylor, S. I., and Kadowaki, T. (2000) Diabetes 49, 1880-1889
20. Terauchi, Y., Matsui, J., Suzuki, R., Kubota, N., Komeda, K., Aizawa, S., Eto, K., Kimura, S., Nagai, R., Tobe, K., Lienhard, G. E., and Kadowaki, T. (2003) J. Biol. Chem. 278, 14284-14290
21. Kitamura, T., Kitamura, Y., Nakae, J., Giordano, A., Cinti, S., Kahn, C. R., Efstratiadis, A., and Accili, D. (2004) J. Clin. Invest. 113, 209-219
22. Kido, Y., Burks, D. J., Withers, D., Bruning, J. C., Kahn, C. R., White, M. F., and Accili, D. (2000) J. Clin. Invest. 105, 199-205
23. Kitamura, T., Nakae, J., Kitamura, Y., Kido, Y., Biggs, W. H., 3rd, Wright, C. V., White, M. F., Arden, K. C., and Accili, D. (2002) J. Clin. Invest. 110, 1839-1847
24. Kitamura, Y. I., Kitamura, T., Kruse, J. P., Raum, J. C., Stein, R., Gu, W., and Accili, D. (2005) Cell. Metab. 2, 153-163
25. Kulkarni, R. N., Winnay, J. N., Daniels, M., Brüning, J. C., Flier, S. N., Hanahan, D., and Kahn, C. R. (1999) J. Clin. Invest. 104, R69-75
26. Gromada, J., Franklin, I., and Wollheim, C. B. (2007) Endocr. Rev. 28, 84-116
27. Kim, J. J., Kido, Y., Scherer, P. E., White, M. F., and Accili, D. (2007) Am. J. Physiol. Endocrinol Metab. 292, E1694-E1701
28. Okamoto, H., Hribal, M. L., Lin, H. V., Bennett, W. R., Ward, A., and Accili, D. (2006) J. Clin. Invest. 116, 775-782
29. Kubota, N., Kubota, T., Itoh, S., Kumagai, H., Kozono, H., Takamoto, I., Mineyama, T., Ogata, H., Tokuyama, K., Ohsugi, M., Sasako, T., Moroi, M., Sugi, K., Kakuta, S., Iwakura, Y., Noda, T., Ohnishi, S., Nagai, R., Tobe, K., Terauchi, Y., Ueki, K., and Kadowaki, T. (2008) Cell. Metab. 8, 49-64
30. Johnson, J. D., Ahmed, N. T., Luciani, D. S., Han, Z., Tran, H., Fujita, J., Misler, S., Edlund, H., and Polonsky, K. S. (2003) J. Clin. Invest. 111, 1147-1160
31. Kushner, J. A., Ye, J., Schubert, M., Burks, D. J., Dow, M. A., Flint, C. L., Dutta, S., Wright, C. V., Montminy, M. R., and White, M. F. (2002) J. Clin. Invest. 109, 1193-1201
32. Lin, X., Taguchi, A., Park, S., Kushner, J. A., Li, F., Li, Y., and White, M. F. (2004) J. Clin. Invest. 114, 908-916
33. Guillam, M. T., Hümmler, E., Schaerer, E., Yeh, J. I., Birnbaum, M. J., Beermann, F., Schmidt, A., Dériaz, N., Thorens, B., and Wu, J. Y. (1997) Nat. Genet. 17, 327-330
34. Olbrot, M., Rud, J., Moss, L. G., and Sharma, A. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 6737-6742
35. Matsuoka, T. A., Zhao, L., Artner, I., Jarrett, H. W., Friedman, D., Means, A., and Stein, R. (2003) Mol. Cell. Biol. 23, 6049-6062
36. Matsuoka, T. A., Artner, I., Henderson, E., Means, A., Sander, M., and Stein, R. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 2930-2933
37. Ueki, K., Okada, T., Hu, J., Liew, C. W., Assmann, A., Dahlgren, G. M., Peters, J. L., Shackman, J. G., Zhang, M., Artner, I., Satin, L. S., Stein, R., Holzenberger, M., Kennedy, R. T., Kahn, C. R., and Kulkarni, R. N. (2006) Nat. Genet. 38, 583-588
38. Nakae, J., Biggs, W. H., 3rd, Kitamura, T., Cavenee, W. K., Wright, C. V., Arden, K. C., and Accili, D. (2002) Nat. Genet. 32, 245-253
39. Hennige, A. M., Burks, D. J., Ozcan, U., Kulkarni, R. N., Ye, J., Park, S., Schubert, M., Fisher, T. L., Dow, M. A., Leshan, R., Zakaria, M., Mossa-Basha, M., and White, M. F. (2003) J. Clin. Invest. 112, 1521-1532
40. Kulkarni, R. N., Brüning, J. C., Winnay, J. N., Postic, C., Magnuson, M. A., and Kahn, C. R. (1999) Cell 96, 329-339
41. Withers, D. J., Burks, D. J., Towery, H. H., Altamuro, S. L., Flint, C. L., and White, M. F. (1999) Nat. Genet. 23, 32-40
42. Okada, T., Liew, C. W., Hu, J., Hinault, C., Michael, M. D., Krtzfeldt, J., Yin, C., Holzenberger, M., Stoffel, M., and Kulkarni, R. N. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 8977-8982
43. Kido, Y., Nakae, J., Hribal, M. L., Xuan, S., Efstratiadis, A., and Accili, D. (2002) J. Biol. Chem. 277, 36740-36747
44. Frattali, A. L., and Pessin, J. E. (1993) J. Biol. Chem. 268, 7393-7400
45. Buteau, J., Shlien, A., Foisy, S., and Accili, D. (2007) J. Biol. Chem. 282, 287-293
46. Weng, J., Li, Y., Xu, W., Shi, L., Zhang, Q., Zhu, D., Hu, Y., Zhou, Z., Yan, X., Tian, H., Ran, X., Luo, Z., Xian, J., Yan, L., Li, F., Zeng, L., Chen, Y., Yang, L., Yan, S., Liu, J., Li, M., Fu, Z., and Cheng, H. (2008) Lancet 371, 1753-1760
47. Greenwood, R. H., Mahler, R. F., and Hales, C. N. (1976) Lancet 1, 444-447
48. Dong, X. C., Copps, K. D., Guo, S., Li, Y., Kollipara, R., DePinho, R. A., and White, M. F. (2008) Cell. Metab. 8, 65-76