Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice

Journal of Biological Chemistry

Volumn 278, Issue 16, 2003, Pages 14284-14290

  Terauchi, Yasuo ^a,b   Matsui, Junji ^a   Suzuki, Ryo ^a,b   Kubota, Naoto ^a,b   Komeda, Kajuro ^c   Aizawa, Shinichi ^d   Eto, Kazuhiro ^a,b   Kimura, Satoshi ^a   Nagai, Ryozo ^a   Tobe, Kazuyuki ^a,b   Lienhard, Gustav E ^e   Kadowaki, Takashi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKYO MEDICAL UNIVERSITY   (Japan)

^d RIKEN   (Japan)

^e DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; ENZYMES; FUNCTIONS; GLUCOSE; GROWTH KINETICS; HEMODYNAMICS; INSULIN;

INSULIN RECEPTORS;

GENETIC ENGINEERING;

GLUCOSE TRANSPORTER 2; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 2; INSULIN RECEPTOR SUBSTRATE 3; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; GLUCOSE; GLUCOSE TRANSPORTER; HOMEODOMAIN PROTEIN; INSULIN; INSULIN PROMOTER FACTOR 1; INSULIN RECEPTOR SUBSTRATE 2 PROTEIN; INSULIN RECEPTOR SUBSTRATE-2 PROTEIN; IRS3 PROTEIN, MOUSE; PHOSPHOPROTEIN; SIGNAL PEPTIDE; TRANSACTIVATOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE SEVERITY; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; HEREDITY; HYPERGLYCEMIA; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CBA MOUSE; CROSS BREEDING; DOSE RESPONSE; FEMALE; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MOUSE MUTANT; MUTATION; PANCREAS ISLET; PHYSIOLOGY; SPECIES DIFFERENCE; TIME;

ANIMALIA;

ANIMALS; BLOOD GLUCOSE; CROSSES, GENETIC; DIABETES MELLITUS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENOTYPE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 2; HOMEODOMAIN PROTEINS; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; MONOSACCHARIDE TRANSPORT PROTEINS; MUTATION; PHOSPHOPROTEINS; SPECIES SPECIFICITY; TIME FACTORS; TRANS-ACTIVATORS;

EID: 0038529802     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211045200     Document Type: Article

References (29)

1. Moller, D. E. (1994) Diabetes 43, 1394-1401
2. Terauchi, Y., and Kadowaki, T. (2002) Endocr. J. 49, 247-264
3. White, M. F., Maron, R., and Kahn, C. R. (1985) Nature 318, 183-186
4. Kadowaki, T., Koyasu, S., Nishida, E., Tobe, K., Izumi, T., Takaku, F., Sakai, H., Yahara, I., and Kasuga, M. (1987) J. Biol. Chem. 262, 7342-7350
5. Shemer, J., Ademo, M., Wilson, G. L., Heffez, D., Zick, Y., and LeRoith, D. (1987) J. Biol. Chem. 262, 15476-15482
6. Sun, X. J., Wang, L. M., Zhang, Y., Yenush, L., Myers, M. G., Jr., Glasheen, E., Lane, W. S., Pierce, J. H., and White, M. F. (1995) Nature 377, 173-177
7. Lavan, B. E., Lane, W. S., and Lienhard, G. E. (1997) J. Biol. Chem. 272, 11439-11443
8. Lavan, B. E., Fantin, V. R., Chang, E. T., Lane, W. S., Keller, S. R., and Lienhard, G. E. (1997) J. Biol. Chem. 272, 21403-21407
9. Tamemoto, H., Kadowaki, T., Tobe, K., Yagi, T., Sakura, H., Hayakawa, T., Terauchi, Y., Ueki, K., Kaburagi, Y., Satoh, S., Sekihara, H., Yoshioka, S., Horikoshi, H., Furuta, Y., Ikawa, Y., Kasuga, M., Yazaki, Y., and Aizawa, S. (1994) Nature 372, 182-186
10. Araki, E., Lipes, M. A., Patti, M. E., Brüning, J. C., Haag, I. B., Johnson, R. S., and Kahn, C.R. (1994) Nature 372, 186-190
11. Terauchi, Y., Iwamoto, K., Tamemoto, H., Komeda, K., Ishii, C., Kanazawa, Y., Asanuma, N., Aizawa, T., Akanuma, Y., Yasuda, K., Kodama, T., Tobe, Y., Yazaki, Y., and Kadowaki, T. (1997) J. Clin. Invest. 99, 861-866
12. Patti, M. E., Sun, X. J., Brüning, J. C., Araki, E., Lipes, M. A., White, M. F., and Kahn, C. R. (1995) J. Biol. Chem. 270, 24670-24673
13. Tobe, K., Tamemoto, H., Yamauchi, T., Aizawa, S., Yazaki, Y., and Kadowaki, T. (1995) J. Biol. Chem. 270, 5698-5701
14. Yamauchi, T., Tobe, K., Tamemoto, H., Ueki, K., Kaburagi, Y., Yamamoto-Honda, R., Takahashi, Y., Yoshizawa, F., Aizawa, S., Akanuma, Y., Sonenberg, N., Yazaki, Y., and Kadowaki, T. (1996) Mol. Cell. Biol. 16, 3074-3084
15. Withers, D. J., Gutierrez, J. S., Towery, H., Burks, D. J., Ren, J. M., Previs, S., Zhang, Y., Bernal, D., Pons, S., Shulman, G. I., Bonner-Weir, S., and White, M. F. (1998) Nature 391, 900-904
16. Kubota, N., Tobe, K., Terauchi, Y., Eto, K., Yamauchi, T., Tsubamoto, Y., Komeda, K., Nakano, R., Miki, H., Suzuki, R., Satoh, S., Sekihara, H., Sciacchitano, S., Akanuma, Y., Aizawa, S., Nagai, R., Kimura, S., Taylor, S. I., and Kadowaki, T. (2000) Diabetes 49, 1880-1889
17. Withers, D, J., Burks, D. J., Towery, H. H., Altamuro, S. L., Flint, C. L., and White, M. F. (1999) Nat. Genet. 23, 32-40
18. Brüning, J. C., Winnay, J., Bonner-Weir, S., Taylor, S. I., Accili, D., and Kahn, C. R. (1997) Cell 88, 561-572
19. Liu, S. C., Wang, Q., Lienhard, G. E., and Keller, S. R. (1999) J. Biol. Chem. 274, 18093-18099
20. Lanstsen, P. G., Michael, M. D., Crute, B. E., Cohen, S. E., Ueki, K., Kulkarni, R. N., Keller, S. R., Lienhard, G. E., and Kahn, C. R. (2003) Genes Dev., in press
21. Terauchi, Y., Tsuji, Y., Satoh, S., Minoura, H., Murakami, K., Okuno, A., Inukai, K., Asano, T., Kaburagi, Y., Ueki, K., Nakajima, H., Hanafusa, T., Matsuzawa, Y., Sekihara, H., Yin, Y., Barrett, J. C., Oda, H., Ishikawa, T., Akanuma, Y., Komuro, I., Suzuki, M., Yamamura, K., Kodama, T., Suzuki, H., Koyasu, S., Aizawa, S., Tobe, K., Fukui, Y., Yazaki, Y., and Kadowaki, T. (1999) Nat. Genet. 21, 230-235
22. Kubota, N., Terauchi, Y., Miki, H., Tamemoto, H., Yamauchi, T., Komeda, K., Nakano, R., Ishii, C., Sugiyama, T., Eto, K., Tsubamoto, T., Okuno, A., Murakami, K., Ezaki, O., Hasegawa, G., Naito, M., Toyoshima, Y., Tanaka, S., Shiota, K., Aizawa, S., Nagai, R., Tobe, K., Kimura, S., and Kadowaki, T. (1999) Mol. Cell 4, 597-609
23. Ishii, C., Kawazu, S., Utsugi, T., Ito, Y., Ohno, T., Kato, N., Shimizu, M., Tomono, S., Nagai, R., and Komeda, K. (1996) Diabetes Res. 31, 1-18
24. Watada, H., Kajimoto, Y., Umayahara, Y., Matsuoka, T., Kaneto, H., Fujitani, Y., Kamada, T., Kawamori, R., and Yamasaki, Y. (1996) Diabetes 45, 1478-1488
25. Kaneto, H., Kajimoto, Y., Miyagawa, J., Matsuoka, T., Fujitani, Y., Umayahara, Y., Hanafusa, T., Matsuzawa, Y., Yamasaki, Y., and Hori, M. (1999) Diabetes 48, 2398-2406
26. Eto, K., Tsubamoto, Y., Terauchi, Y., Sugiyama, T., Kishimoto, T., Takahashi, N., Yamauchi, N., Kubota, N., Murayama, S., Aizawa, T., Akanuma, Y., Aizawa, S., Kasai, H., Yazaki, Y., and Kadowaki, T. (1999) Science 283, 981-985
27. Eto, K., Suga, S., Wakui, M., Tsubamoto, Y., Terauchi, Y., Taka, J., Aizawa, S., Noda, M., Kimura, S., Kasai, H., and Kadowaki, T. (1999) J. Biol. Chem. 274, 25386-25392
28. Kushner, J. A., Ye, J., Schubert, M., Burks, D. J., Dow, M. A., Flint, C. L., Dutta, S., Wright, C. V., Montminy, M. R., and White, M. F. (2002) J. Clin. Invest. 109, 1193-1201
29. Kido, Y., Philippe, N., Schaffer, A. A., and Accili, D. (2000) Diabetes 49, 589-596