CD4+CD25-mTGFβ+ T cells induced by nasal application of ovalbumin transfer tolerance in a therapeutic model of asthma

International Immunology

Volumn 23, Issue 1, 2011, Pages 17-27

  Pellaton Longaretti, Céline ^a   Boudousquié, Caroline ^a   Barbier, Nathalie ^a   Barbey, Catherine ^a,c   Argiroffo, Constance Barazzone ^b   Donati, Yves ^b   Sauty, Alain ^a   Spertini, Francxois ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c MERCK SERONO S A   (Switzerland)

Author keywords

Asthma; CD25; Immunotherapy; T regulatory cells; TGFb; Tolerance

Indexed keywords

EOSINOPHIL PEROXIDASE; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; OVALBUMIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; ALLERGEN; CYTOKINE; IL2RA PROTEIN, MOUSE; INTERLEUKIN 2 RECEPTOR ALPHA;

AEROSOL; ALLERGEN SPECIFIC IMMUNOTHERAPY; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHITIS; CD4+ CD25+ T LYMPHOCYTE; CD4+ CD25- T CELL; CD4+ T LYMPHOCYTE; CELL TRANSFER; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOSE RESPONSE; DOWN REGULATION; DRUG BINDING; DRUG DOSE ESCALATION; DRUG MECHANISM; ENZYME INHIBITION; EOSINOPHIL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IMMUNOTHERAPY; INFLAMMATORY CELL; LUNG; LUNG LAVAGE; LYMPH NODE; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; T CELL DEPLETION; TH1 CELL; TH2 CELL; ANIMAL; ASTHMA; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL PROLIFERATION; DESENSITIZATION; DRUG SCREENING; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; METABOLISM; METHODOLOGY; REGULATORY T LYMPHOCYTE;

ADMINISTRATION, INTRANASAL; ALLERGENS; ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CYTOKINES; DESENSITIZATION, IMMUNOLOGIC; DRUG EVALUATION, PRECLINICAL; IMMUNE TOLERANCE; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LUNG; LYMPH NODES; MICE; MICE, INBRED BALB C; OVALBUMIN; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH2 CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 78650335764     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxq453     Document Type: Article

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