Phospholipase-D activity and inflammatory response induced by brown spider dermonecrotic toxin: Endothelial cell membrane phospholipids as targets for toxicity

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1811, Issue 2, 2011, Pages 84-96

  Chaim, Olga M ^a,b   Da Silveira, Rafael B ^c   Trevisan Silva, Dilza ^b   Ferrer, Valéria P ^b   Sade, Youssef B ^b   Bóia Ferreira, Mariana ^b   Gremski, Luiza H ^a   Gremski, Waldemiro ^b,d   Senff Ribeiro, Andrea ^b   Takahashi, Hélio K ^a   Toledo, Marcos S ^a   Nader, Helena B ^a   Veiga, Silvio S ^b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^c STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

^d PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

Dermonecrotic toxin; Endothelial cell; Inflammatory response; Loxosceles intermedia; Phospholipase D; Venom

Indexed keywords

ALANINE; ANTISERUM; CHOLINE; HISTIDINE; ISOPROTEIN; MEMBRANE PHOSPHOLIPID; PHOSPHOLIPASE D; SPHINGOMYELIN PHOSPHODIESTERASE; SPIDER VENOM;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURFACE; CIRCULAR DICHROISM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SPECIFICITY; FLUOROMETRY; GENE MUTATION; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; IMMUNOBLOTTING; IN VITRO STUDY; INFLAMMATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTEIN TARGETING; RABBIT; SITE DIRECTED MUTAGENESIS; SKIN MANIFESTATION; SKIN NECROSIS; SURFACE PROPERTY;

ANIMALS; AORTA; CELL MEMBRANE; CELLS, CULTURED; CHOLINE; ENDOTHELIAL CELLS; INFLAMMATION; INSECT PROTEINS; LIPID METABOLISM; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASE D; PHOSPHOLIPIDS; RABBITS; RECOMBINANT PROTEINS; SPIDER VENOMS;

ARANEAE; LOXOSCELES; LOXOSCELES INTERMEDIA; ORYCTOLAGUS CUNICULUS;

EID: 78650158082     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2010.11.005     Document Type: Article

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