Identification, cloning and functional characterization of a novel dermonecrotic toxin (phospholipase D) from brown spider (Loxosceles intermedia) venom

Biochimica et Biophysica Acta - General Subjects

Volumn 1780, Issue 2, 2008, Pages 167-178

  Appel, Marcia Helena ^a   da Silveira, Rafael Bertoni ^a,b   Chaim, Olga Meiri ^a,b   Paludo, Kátia Sabrina ^a   Silva, Dilza Trevisan ^a   Chaves, Daniele M ^a   da Silva, Paulo Henrique ^a   Mangili, Oldemir C ^a   Senff Ribeiro, Andrea ^a   Gremski, Waldemiro ^a,c   Nader, Helena B ^b   Veiga, Silvio Sanches ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

Dermonecrotic toxin; Loxosceles; Phospholipase D; Sphingomyelinase; Venom

Indexed keywords

DERMONECROTIC TOXIN; PHOSPHOLIPASE D; SPIDER VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME ACTIVITY; GEL ELECTROPHORESIS; IMMUNOBLOTTING; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN PURIFICATION; SKIN EDEMA; SKIN NECROSIS; SPIDER; THROMBOCYTE AGGREGATION;

AMINO ACID SEQUENCE; ANIMALS; CAPILLARY PERMEABILITY; CLONING, MOLECULAR; DERMIS; DNA, COMPLEMENTARY; EDEMA; MICE; MOLECULAR SEQUENCE DATA; NECROSIS; PHOSPHOLIPASE D; PHOSPHORIC DIESTER HYDROLASES; PHYLOGENY; PROTEIN ISOFORMS; RABBITS; RECOMBINANT PROTEINS; SPIDER VENOMS; SPIDERS;

ANIMALIA; ARANEAE; LOXOSCELES; LOXOSCELES INTERMEDIA; MUS; ORYCTOLAGUS CUNICULUS;

EID: 38549123446     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2007.11.007     Document Type: Article

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