Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E2 release via C/EBPβ in human bronchial epithelial cells

Biochemical Journal

Volumn 412, Issue 1, 2008, Pages 153-162

  He, Donghong ^a   Natarajan, Viswanathan ^a   Stern, Randi ^a   Gorshkova, Irina A ^a   Solway, Julian ^a   Spannhake, Ernst Wm ^b   Zhao, Yutong ^a  

^a Gordon Center for Integrative Science   (United States)

^b The Johns Hopkins University   (United States)

Author keywords

Bioactive phospholipid; Gene expression; Receptor tyrosine kinase (RTK); Signal transduction; Transcription factor

Indexed keywords

ENZYME ACTIVITY; GROWTH KINETICS; PHOSPHOLIPIDS; PHOSPHORYLATION; RNA;

RECEPTOR TYROSINE KINASE (RTK); TRANSACTIVATION; TYROSINE KINASE;

GENE EXPRESSION;

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSOPHOSPHATIDIC ACID; PROSTAGLANDIN E2; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; BRONCHUS; DOWN REGULATION; EPITHELIUM CELL; HORMONE RELEASE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

BRONCHI; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; EPITHELIAL CELLS; HUMANS; LYSOPHOSPHOLIPIDS; MODELS, BIOLOGICAL; NF-KAPPA B; PHOSPHOLIPASE D; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-JUN; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY MUCOSA; RNA, SMALL INTERFERING; TRANS-ACTIVATION (GENETICS);

EID: 43549117267     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071649     Document Type: Article

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