Blood coagulation: The outstanding hydrophobic residues

Current Biology

Volumn 10, Issue 6, 2000, Pages

  Pellequer, Jean Luc ^a   Gale, Andrew J ^a   Getzoff, Elizabeth D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034704833     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00373-0     Document Type: Review

References (17)

1. Kane WH, Davie EW: Blood coagulation factors V and VIII: structure and functional similarities and their relationship to hemorrhagic and thrombotic disorders. Blood 1988, 71:539-555.
2. Zwaal RFA, Comfurius P, Severs EM: Lipid-protein interactions in blood coagulation. Biochim Biophys Acta 1998, 1376:433-453.
3. Gilbert GE, Drinkwater D: Specific membrane binding of factor VIII is mediated by O-phospho-L-serine, a moiety of phosphatidylserine. Biochemistry 1993, 32:9577-9585.
4. Comfurius P, Smeets EF, Willems GM, Severs EM, Zwaal RFA: Assembly of the prothrombinase complex on lipid vesicles depends on the stereochemical configuration of the polar headgroup of phosphatidylserine. Biochemistry 1994, 33:10319-10324.
5. Macedo-Ribeiro S, Bode W, Huber R, Quinn-Allen MA, Kim SW, Ortel TL, Bourenkov GP, Bartunik HD, Stubbs MT, Kane WH, et al.: Crystal structures of the membrane-binding C2 domain of human coagulation factor V. Nature 1999, 402:434-439.
6. Pratt KP, Shen BW, Takeshima K, Davie EW, Fujikawa K, Stoddard BL: Structure of the C2 domain of human factor VIII at 1.5 A resolution. Nature 1999, 402:439-442.
7. Baumgartner S, Hofmann K, Chiquet-Ehrismann R, Bucher P: The discoidin domain family revisited: new members from prokaryotes and a homology-based fold prediction. Protein Sci 1998, 7:1626-1631.
8. Pellequer J-L, Gale AJ, Griffin JH, Getzoff ED: Homology models of the C domains of blood coagulation factors V and VIII: a proposed membrane binding mode for FV and FVIII C2 domains. Blood Cells Mol Dis 1998, 24:448-461.
9. Villoutreix BO, Bucher P, Hofmann K, Baumgartner S, Dahlbäck B: Molecular models for the two discoidin domains of human blood coagulation factor V. J Mol Model 1998, 4:268-275.
10. Ito N, Phillips SEV, Yadav KDS, Knowles PF: Crystal structure of a free radical enzyme, galactose oxidase. J Mol Biol 1994, 238:794-814.
11. Chelvanayagam G, Roy G, Argos P: Easy adaptation of protein structure to sequence. Protein Eng 1994, 7:173-184.
12. 2+-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V. Nature Struct Biol 1995, 2:968-974.
13. Koppaka V, Talbot WF, Zhai X, Lentz BR: Roles of cofactor Va heavy and light chains in protein and lipid rearrangements associated with the formation of a bovine cofactor Va-membrane complex. Biophys J 1997, 73:2638-2652.
14. Stoylova SS, Lenting PJ, Kemball-Cook G, Holzenburg A: Electron crystallography of human blood coagulation factor VIII bound to phospholipid monolayers. J Biol Chem 1999, 274:36573-36578.
15. Kemball-Cook G, Tuddenham EGD, Wacey AI: The factor VIII structure and mutation resource site: HAMSTeRS version 4. Nucleic Acids Res 1998, 26:216-219.
16. Gale AJ, Pellequer JL, Getzoff ED, Griffin JH: Structural basis for hemophilia A caused by mutations in the C domains of blood coagulation factor VIII. Thromb Haemost 2000, 83:78-85.
17. Pipe SW, Kaufman RJ: Factor VIII C2 domain missense mutations exhibit defective trafficking of biologically functional proteins. J Biol Chem 1996, 271:25671-25676.