Role of two active site Glu residues in the molecular action of botulinum neurotoxin endopeptidase

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1774, Issue 2, 2007, Pages 213-222

  Kukreja, Roshan V ^a   Sharma, Sapna ^a   Cai, Shuowei ^a   Singh, Bal Ram ^a  

^a UNIVERSITY OF MASSACHUSETTS DARTMOUTH   (United States)

Author keywords

Botulinum neurotoxin; Endopeptidase; Light chain; Site directed mutagenesis; SNAP 25

Indexed keywords

BOTULINUM TOXIN A; GLUTATHIONE; PROTEINASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; ENZYME ACTIVITY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; SUBSTITUTION REACTION;

BASE SEQUENCE; BINDING SITES; BOTULINUM TOXINS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; ENDOPEPTIDASES; GLUTAMIC ACID; HYDROLYSIS; KINETICS; MUTAGENESIS, SITE-DIRECTED; SPECTROMETRY, FLUORESCENCE; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25;

EID: 33846818367     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2006.11.007     Document Type: Article

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