-
1
-
-
0034060152
-
Development of our current understanding of bioactive lysophospholipids
-
Moolenaar W.H. Development of our current understanding of bioactive lysophospholipids. Ann. N. Y. Acad. Sci. 905:2000;1-10.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.905
, pp. 1-10
-
-
Moolenaar, W.H.1
-
2
-
-
0035025354
-
Physiological responses to lysophosphatidic acid and related glycero-phospholipids
-
Tigyi G. Physiological responses to lysophosphatidic acid and related glycero-phospholipids. Prostaglandins. 64:2001;47-62.
-
(2001)
Prostaglandins
, vol.64
, pp. 47-62
-
-
Tigyi, G.1
-
4
-
-
0035976579
-
Lysophospholipids-receptor revelations
-
Hla T., et al. Lysophospholipids-receptor revelations. Science. 294:2001;1875-1878.
-
(2001)
Science
, vol.294
, pp. 1875-1878
-
-
Hla, T.1
-
6
-
-
0029836932
-
Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
-
Hecht J.H., et al. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J. Cell Biol. 135:1996;1071-1083.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1071-1083
-
-
Hecht, J.H.1
-
7
-
-
0032568613
-
A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid
-
Fukushima N., et al. A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid. Proc. Natl. Acad. Sci. U. S. A. 95:1998;6151-6156.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6151-6156
-
-
Fukushima, N.1
-
8
-
-
0031584825
-
Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid
-
An S., et al. Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid. Biochem. Biophys. Res. Commun. 231:1997;619-622.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.231
, pp. 619-622
-
-
An, S.1
-
9
-
-
0028899593
-
Characterization of edg-2, a human homologue of the Xenopus maternal transcript G10 from endothelial cells
-
Hla T., et al. Characterization of edg-2, a human homologue of the Xenopus maternal transcript G10 from endothelial cells. Biochim. Biophys. Acta. 1260:1995;227-229.
-
(1995)
Biochim. Biophys. Acta
, vol.1260
, pp. 227-229
-
-
Hla, T.1
-
10
-
-
0033600761
-
Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid
-
Bandoh K., et al. Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid. J. Biol. Chem. 274:1999;27776-27785.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27776-27785
-
-
Bandoh, K.1
-
12
-
-
0034700050
-
Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior
-
Contos J.J., et al. Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Proc. Natl. Acad. Sci. U. S. A. 97:2000;13384-13389.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 13384-13389
-
-
Contos, J.J.1
-
13
-
-
0036786445
-
Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2)
-
Contos J.J., et al. Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Mol. Cell. Biol. 22:2002;6921-6929.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6921-6929
-
-
Contos, J.J.1
-
14
-
-
0035895989
-
Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent
-
Hooks S.B., et al. Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent. J. Biol. Chem. 276:2001;4611-4621.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4611-4621
-
-
Hooks, S.B.1
-
15
-
-
0037162084
-
Structure-activity relationships of lysophosphatidic acid analogs
-
Lynch K.R., Macdonald T.L. Structure-activity relationships of lysophosphatidic acid analogs. Biochim. Biophys. Acta. 1582:2002;289-294.
-
(2002)
Biochim. Biophys. Acta
, vol.1582
, pp. 289-294
-
-
Lynch, K.R.1
Macdonald, T.L.2
-
16
-
-
0037422595
-
From the cover: Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist
-
McIntyre T.M., et al. From the cover: identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist. Proc. Natl. Acad. Sci. U. S. A. 100:2003;131-136.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 131-136
-
-
McIntyre, T.M.1
-
17
-
-
0036183630
-
The mechanisms of action of PPARs
-
Berger J., Moller D.E. The mechanisms of action of PPARs. Annu. Rev. Med. 53:2002;409-435.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
18
-
-
0036399805
-
PPAR(γ) and glucose homeostasis
-
Picard F., Auwerx J. PPAR(γ) and glucose homeostasis. Annu. Rev. Nutr. 22:2002;167-197.
-
(2002)
Annu. Rev. Nutr.
, vol.22
, pp. 167-197
-
-
Picard, F.1
Auwerx, J.2
-
19
-
-
0021099118
-
Intracellular translocation and metabolism of a fluorescent phosphatidic acid analogue in cultured fibroblasts
-
Pagano R.E., et al. Intracellular translocation and metabolism of a fluorescent phosphatidic acid analogue in cultured fibroblasts. J. Biol. Chem. 258:1983;2034-2040.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 2034-2040
-
-
Pagano, R.E.1
-
20
-
-
0034710631
-
Role of phosphatidic acid phosphatase 2a in uptake of extracellular lipid phosphate mediators
-
Roberts R.Z., Morris A.J. Role of phosphatidic acid phosphatase 2a in uptake of extracellular lipid phosphate mediators. Biochim. Biophys. Acta. 1487:2000;33-49.
-
(2000)
Biochim. Biophys. Acta
, vol.1487
, pp. 33-49
-
-
Roberts, R.Z.1
Morris, A.J.2
-
21
-
-
0024495699
-
Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin
-
Gerrard J.M., Robinson P. Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin. Biochim. Biophys. Acta. 1001:1989;282-285.
-
(1989)
Biochim. Biophys. Acta
, vol.1001
, pp. 282-285
-
-
Gerrard, J.M.1
Robinson, P.2
-
22
-
-
0028986238
-
Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells
-
Fourcade O., et al. Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells. Cell. 80:1995;919-927.
-
(1995)
Cell
, vol.80
, pp. 919-927
-
-
Fourcade, O.1
-
23
-
-
0032037561
-
α2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growth
-
Valet P., et al. α2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growth. J. Clin. Invest. 101:1998;1431-1438.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1431-1438
-
-
Valet, P.1
-
24
-
-
0037189488
-
Expression of ectolipid phosphate phosphohydrolases in 3T3F442A preadipocytes and adipocytes. Involvement in the control of lysophosphatidic acid production
-
Simon M.F., et al. Expression of ectolipid phosphate phosphohydrolases in 3T3F442A preadipocytes and adipocytes. Involvement in the control of lysophosphatidic acid production. J. Biol. Chem. 277:2002;23131-23136.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23131-23136
-
-
Simon, M.F.1
-
25
-
-
0034083409
-
Constitutive and lysophosphatidic acid (LPA)-induced LPA production: Role of phospholipase D and phospholipase A2
-
Eder A.M., et al. Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2. Clin. Cancer Res. 6:2000;2482-2491.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2482-2491
-
-
Eder, A.M.1
-
26
-
-
0037031878
-
Role for 18:1 lysophosphatidic acid as an autocrine mediator in prostate cancer cells
-
Xie Y., et al. Role for 18:1 lysophosphatidic acid as an autocrine mediator in prostate cancer cells. J. Biol. Chem. 277:2002;32516-32526.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32516-32526
-
-
Xie, Y.1
-
27
-
-
0032568216
-
2+ signaling pathways
-
2+ signaling pathways. Curr. Biol. 8:1998;386-392.
-
(1998)
Curr. Biol.
, vol.8
, pp. 386-392
-
-
Van Dijk, M.C.1
-
28
-
-
0022623355
-
Involvement of lysophospholipase D in the production of lysophosphatidic acid in rat plasma
-
Tokumura A., et al. Involvement of lysophospholipase D in the production of lysophosphatidic acid in rat plasma. Biochim. Biophys. Acta. 875:1986;31-38.
-
(1986)
Biochim. Biophys. Acta
, vol.875
, pp. 31-38
-
-
Tokumura, A.1
-
29
-
-
1542359873
-
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production
-
Umezu-Goto M., et al. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. J. Cell Biol. 158:2002;227-233.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 227-233
-
-
Umezu-Goto, M.1
-
30
-
-
0026787698
-
Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein
-
Stracke M.L., et al. Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein. J. Biol. Chem. 267:1992;2524-2529.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 2524-2529
-
-
Stracke, M.L.1
-
31
-
-
0028045941
-
CDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases
-
Murata J., et al. cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases. J. Biol. Chem. 269:1994;30479-30484.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30479-30484
-
-
Murata, J.1
-
32
-
-
0034490045
-
Nucleotide pyrophosphatases/phosphodiesterases on the move
-
Bollen M., et al. Nucleotide pyrophosphatases/phosphodiesterases on the move. Crit. Rev. Biochem. Mol. Biol. 35:2000;393-432.
-
(2000)
Crit. Rev. Biochem. Mol. Biol.
, vol.35
, pp. 393-432
-
-
Bollen, M.1
-
33
-
-
0029013367
-
Autotaxin is an N-linked glycoprotein but the sugar moieties are not needed for its stimulation of cellular motility
-
Stracke M.L., et al. Autotaxin is an N-linked glycoprotein but the sugar moieties are not needed for its stimulation of cellular motility. Melanoma Res. 5:1995;203-209.
-
(1995)
Melanoma Res.
, vol.5
, pp. 203-209
-
-
Stracke, M.L.1
-
34
-
-
0034642507
-
Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells
-
Nam S.W., et al. Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells. Oncogene. 19:2000;241-247.
-
(2000)
Oncogene
, vol.19
, pp. 241-247
-
-
Nam, S.W.1
-
35
-
-
0035884290
-
Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor
-
Nam S.W., et al. Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor. Cancer Res. 61:2001;6938-6944.
-
(2001)
Cancer Res.
, vol.61
, pp. 6938-6944
-
-
Nam, S.W.1
-
36
-
-
0037073806
-
Serum lysophosphatidic acid is produced through diverse phospholipase pathways
-
Aoki J., et al. Serum lysophosphatidic acid is produced through diverse phospholipase pathways. J. Biol. Chem. 277:2002;48737-48744.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48737-48744
-
-
Aoki, J.1
-
37
-
-
0037077199
-
Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood
-
Sano T., et al. Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood. J. Biol. Chem. 277:2002;21197-21206.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21197-21206
-
-
Sano, T.1
-
38
-
-
0028135327
-
Biochemical characterization of human PC-1, an enzyme possessing alkaline phosphodiesterase I and nucleotide pyrophosphatase activities
-
Belli S.I., Goding J.W. Biochemical characterization of human PC-1, an enzyme possessing alkaline phosphodiesterase I and nucleotide pyrophosphatase activities. Eur. J. Biochem. 226:1994;433-443.
-
(1994)
Eur. J. Biochem.
, vol.226
, pp. 433-443
-
-
Belli, S.I.1
Goding, J.W.2
-
39
-
-
0032544691
-
Mammalian lipid phosphate phosphohydrolases
-
Brindley D.N., Waggoner D.W. Mammalian lipid phosphate phosphohydrolases. J. Biol. Chem. 273:1998;24281-24284.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24281-24284
-
-
Brindley, D.N.1
Waggoner, D.W.2
-
40
-
-
0034608826
-
Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1-phosphate and induces cell death
-
Mandala S.M., et al. Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1-phosphate and induces cell death. Proc. Natl. Acad. Sci. U. S. A. 97:2000;7859-7864.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 7859-7864
-
-
Mandala, S.M.1
-
41
-
-
0033564681
-
Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters
-
Jasinska R., et al. Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters. Biochem. J. 340:1999;677-686.
-
(1999)
Biochem. J.
, vol.340
, pp. 677-686
-
-
Jasinska, R.1
-
42
-
-
0032693488
-
Sequential actions of phospholipase D and phosphatidic acid phosphohydrolase 2b generate diglyceride in mammalian cells
-
Sciorra V.A., Morris A.J. Sequential actions of phospholipase D and phosphatidic acid phosphohydrolase 2b generate diglyceride in mammalian cells. Mol. Biol. Cell. 10:1999;3863-3876.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3863-3876
-
-
Sciorra, V.A.1
Morris, A.J.2
-
43
-
-
0034623053
-
2+ control lysophosphatidate signaling through EDG-2 receptors
-
2+ control lysophosphatidate signaling through EDG-2 receptors. J. Biol. Chem. 275:2000;27520-27530.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27520-27530
-
-
Xu, J.1
-
44
-
-
85031146372
-
The human lipid phosphate phosphatase-3 (hLPP-3) decreases the growth, survival, and tumorigenesis of ovarian cancer cells: Validation of the LPA signaling cascade as a target for therapy in ovarian cancer
-
in press
-
Tanyi, J.L. et al. The human lipid phosphate phosphatase-3 (hLPP-3) decreases the growth, survival, and tumorigenesis of ovarian cancer cells: Validation of the LPA signaling cascade as a target for therapy in ovarian cancer. Cancer Res. (in press).
-
Cancer Res.
-
-
Tanyi, J.L.1
-
45
-
-
0033809110
-
Mice mutant for Ppap2c, a homolog of the germ cell migration regulator wunen, are viable and fertile
-
Zhang N., et al. Mice mutant for Ppap2c, a homolog of the germ cell migration regulator wunen, are viable and fertile. Genesis. 27:2000;137-140.
-
(2000)
Genesis
, vol.27
, pp. 137-140
-
-
Zhang, N.1
-
46
-
-
0031105524
-
Cell migration: Don't tread on me
-
Doren M.V., Lehmann R. Cell migration: don't tread on me. Curr. Biol. 7:1997;R148-R150.
-
(1997)
Curr. Biol.
, vol.7
-
-
Doren, M.V.1
Lehmann, R.2
-
47
-
-
0031021247
-
The Drosophila protein Wunen repels migrating germ cells
-
Zhang N., et al. The Drosophila protein Wunen repels migrating germ cells. Nature. 385:1997;64-67.
-
(1997)
Nature
, vol.385
, pp. 64-67
-
-
Zhang, N.1
-
48
-
-
0035071025
-
Spatially restricted activity of a Drosophila lipid phosphatase guides migrating germ cells
-
Starz-Gaiano M., et al. Spatially restricted activity of a Drosophila lipid phosphatase guides migrating germ cells. Development. 128:2001;983-991.
-
(2001)
Development
, vol.128
, pp. 983-991
-
-
Starz-Gaiano, M.1
-
49
-
-
0032480975
-
HMG-CoA reductase guides migrating primordial germ cells
-
Van Doren M., et al. HMG-CoA reductase guides migrating primordial germ cells. Nature. 396:1998;466-469.
-
(1998)
Nature
, vol.396
, pp. 466-469
-
-
Van Doren, M.1
|