FLT3 as a therapeutic target in AML: Still challenging after all these years

Blood

Volumn 116, Issue 24, 2010, Pages 5089-5102

  Kindler, Thomas ^a   Lipka, Daniel B ^b   Fischer, Thomas ^b  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AC 220; AZACITIDINE; CD135 ANTIGEN; CYTARABINE; DAUNORUBICIN; DOVITINIB; ETOPOSIDE; IDARUBICIN; IMATINIB; KW 2449; LACTACYSTIN BETA LACTONE; LESTAURTINIB; LINIFANIB; MIDOSTAURIN; MITOXANTRONE; PLACEBO; PROTEIN TYROSINE KINASE INHIBITOR; SEMAXANIB; SORAFENIB; SU 11249; SUNITINIB; TANDUTINIB; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; BONE PAIN; CANCER COMBINATION CHEMOTHERAPY; CELL COUNT; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; COHORT ANALYSIS; DIARRHEA; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; EDEMA; FATIGUE; GASTROINTESTINAL SYMPTOM; GENE MUTATION; HEADACHE; HUMAN; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; LABORATORY TEST; LEUKEMIA REMISSION; LUNG DISEASE; MAINTENANCE THERAPY; MONOTHERAPY; MULTIPLE CYCLE TREATMENT; MUSCLE WEAKNESS; NAUSEA; NONHUMAN; PERIPHERAL EDEMA; PLEURA EFFUSION; PRIORITY JOURNAL; PROGNOSIS; QT PROLONGATION; RASH; REVIEW; SINGLE DRUG DOSE; VOMITING;

EID: 78650073854     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-04-261867     Document Type: Review

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