메뉴 건너뛰기




Volumn 106, Issue 12, 2005, Pages 3733-3739

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; FLT3 LIGAND; MITOXANTRONE; MIXED LINEAGE LEUKEMIA PROTEIN; NUCLEOPHOSMIN; RAS PROTEIN; STEM CELL FACTOR; TIOGUANINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CEBPA; UNCLASSIFIED DRUG;

EID: 28444449081     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-06-2248     Document Type: Article
Times cited : (613)

References (40)
  • 3
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
    • Grimwade D, Walker H, Oliver F, et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. Blood. 1998;92:2322-2333.
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3
  • 4
    • 0034672269 scopus 로고    scopus 로고
    • Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/Eastern Cooperative Oncology Group Study
    • Slovak ML, Kopecky KJ, Cassileth PA, et al. Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study. Blood. 2000;96:4075-4083.
    • (2000) Blood , vol.96 , pp. 4075-4083
    • Slovak, M.L.1    Kopecky, K.J.2    Cassileth, P.A.3
  • 5
    • 0037108111 scopus 로고    scopus 로고
    • Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: A study from the Acute Leukemia French Association (ALFA)
    • Preudhomme C, Sagot C, Boissel N, et al. Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA). Blood. 2002;100:2717-2723.
    • (2002) Blood , vol.100 , pp. 2717-2723
    • Preudhomme, C.1    Sagot, C.2    Boissel, N.3
  • 6
    • 0037265726 scopus 로고    scopus 로고
    • New mechanisms of AML1 gene alteration in hematological malignancies
    • Roumier C, Fenaux P, Lafage M, et al. New mechanisms of AML1 gene alteration in hematological malignancies. Leukemia. 2003;17:9-16.
    • (2003) Leukemia , vol.17 , pp. 9-16
    • Roumier, C.1    Fenaux, P.2    Lafage, M.3
  • 7
    • 0037441589 scopus 로고    scopus 로고
    • M0 AML, clinical and biologic features of the disease, including AML1 gene mutations: A report of 59 cases by the Groupe Francais d'Hematologie Cellulaire (GFHC) and the Groupe Francais de Cytogenetique Hematologique (GFCH)
    • Roumier C, Eclache V, Imbert M, et al. M0 AML, clinical and biologic features of the disease, including AML1 gene mutations: a report of 59 cases by the Groupe Francais d'Hematologie Cellulaire (GFHC) and the Groupe Francais de Cytogenetique Hematologique (GFCH). Blood. 2003;101:1277-1283.
    • (2003) Blood , vol.101 , pp. 1277-1283
    • Roumier, C.1    Eclache, V.2    Imbert, M.3
  • 8
    • 0035093813 scopus 로고    scopus 로고
    • Dominantnegative mutations of CEBPA, encoding CCAAT/ enhancer binding protein-a, in acute myeloid leukemia
    • Pabst T, Mueller BU, Zhang P, et al. Dominantnegative mutations of CEBPA, encoding CCAAT/ enhancer binding protein-a, in acute myeloid leukemia. Nat Genet. 2001;27:267-270.
    • (2001) Nat Genet , vol.27 , pp. 267-270
    • Pabst, T.1    Mueller, B.U.2    Zhang, P.3
  • 9
    • 1442356729 scopus 로고    scopus 로고
    • CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: Prognostic relevance and analysis of cooperating mutations
    • Frohling S, Schlenk RF, Stolze I, et al. CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations. J Clin Oncol. 2004;22:624-633.
    • (2004) J Clin Oncol , vol.22 , pp. 624-633
    • Frohling, S.1    Schlenk, R.F.2    Stolze, I.3
  • 10
    • 0036659931 scopus 로고    scopus 로고
    • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
    • Schnittger S, Schoch C, Dugas M, et al. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood. 2002;100:59-66.
    • (2002) Blood , vol.100 , pp. 59-66
    • Schnittger, S.1    Schoch, C.2    Dugas, M.3
  • 11
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede C, Steudel C, Mohr B, et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood. 2002;99:4326-4335.
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3
  • 12
    • 0037409885 scopus 로고    scopus 로고
    • Prognostic implications of the presence of FLT3 mutations in patients with acute myeloid leukemia
    • Kottaridis PD, Gale RE, Linch DC. Prognostic implications of the presence of FLT3 mutations in patients with acute myeloid leukemia. Leuk Lymphoma. 2003;44:905-913.
    • (2003) Leuk Lymphoma , vol.44 , pp. 905-913
    • Kottaridis, P.D.1    Gale, R.E.2    Linch, D.C.3
  • 13
    • 3943068350 scopus 로고    scopus 로고
    • KIT activating mutations: Incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication
    • Beghini A, Ripamonti CB, Cairoli R, et al. KIT activating mutations: incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication. Haematologica. 2004;89:920-925.
    • (2004) Haematologica , vol.89 , pp. 920-925
    • Beghini, A.1    Ripamonti, C.B.2    Cairoli, R.3
  • 14
    • 0033134792 scopus 로고    scopus 로고
    • Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia
    • Kiyoi H, Naoe T, Nakano Y, et al. Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. Blood. 1999;93:3074-3080.
    • (1999) Blood , vol.93 , pp. 3074-3080
    • Kiyoi, H.1    Naoe, T.2    Nakano, Y.3
  • 15
    • 0028084756 scopus 로고
    • Molecular rearrangement of the ALL-1 gene in acute myeloid leukemia without cytogenetic evidence of 11q23 chromosomal translocations
    • Caligiuri MA, Schichman SA, Strout MP, et al. Molecular rearrangement of the ALL-1 gene in acute myeloid leukemia without cytogenetic evidence of 11q23 chromosomal translocations. Cancer Res. 1994;54:370-373.
    • (1994) Cancer Res , vol.54 , pp. 370-373
    • Caligiuri, M.A.1    Schichman, S.A.2    Strout, M.P.3
  • 16
    • 0034097609 scopus 로고    scopus 로고
    • Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AML
    • Schnittger S, Kinkelin U, Schoch C, et al. Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AML. Leukemia. 2000;14:796-804.
    • (2000) Leukemia , vol.14 , pp. 796-804
    • Schnittger, S.1    Kinkelin, U.2    Schoch, C.3
  • 17
    • 0035204051 scopus 로고    scopus 로고
    • Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapyrelated acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy
    • Christiansen DH, Pedersen-Bjergaard J. Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapyrelated acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy. Leukemia. 2001;15:1848-1851.
    • (2001) Leukemia , vol.15 , pp. 1848-1851
    • Christiansen, D.H.1    Pedersen-Bjergaard, J.2
  • 18
    • 0036682174 scopus 로고    scopus 로고
    • Prognostic significance of partial tandem duplications of the MLL gene in adult patients 16 to 60 years old with acute myeloid leukemia and normal cytogenetics: A study of the Acute Myeloid Leukemia Study Group Ulm
    • Dohner K, Tobis K, Ulrich R, et al. Prognostic significance of partial tandem duplications of the MLL gene in adult patients 16 to 60 years old with acute myeloid leukemia and normal cytogenetics: a study of the Acute Myeloid Leukemia Study Group Ulm. J Clin Oncol. 2002;20:3254-3261.
    • (2002) J Clin Oncol , vol.20 , pp. 3254-3261
    • Dohner, K.1    Tobis, K.2    Ulrich, R.3
  • 19
    • 0038208034 scopus 로고    scopus 로고
    • Comparative analysis of MLL partial tandem duplication and FLT3 internal tandem duplication mutations in 956 adult patients with acute myeloid leukemia
    • Steudel C, Wermke M, Schaich M, et al. Comparative analysis of MLL partial tandem duplication and FLT3 internal tandem duplication mutations in 956 adult patients with acute myeloid leukemia. Genes Chromosomes Cancer. 2003;37:237-251.
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 237-251
    • Steudel, C.1    Wermke, M.2    Schaich, M.3
  • 20
    • 19944427850 scopus 로고    scopus 로고
    • Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
    • Falini B, Mecucci C, Tiacci E, et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med. 2005;352:254-266.
    • (2005) N Engl J Med , vol.352 , pp. 254-266
    • Falini, B.1    Mecucci, C.2    Tiacci, E.3
  • 21
    • 23044459136 scopus 로고    scopus 로고
    • Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMcAML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem cell maintenance
    • Alcalay M, Tiacci E, Bergomas R, et al. Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMcAML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem cell maintenance. Blood. 2005;106:899-902.
    • (2005) Blood , vol.106 , pp. 899-902
    • Alcalay, M.1    Tiacci, E.2    Bergomas, R.3
  • 22
    • 0037217950 scopus 로고    scopus 로고
    • Early blast clearance by remission induction therapy is a major independent prognostic factor for both achievement of complete remission and longterm outcome in acute myeloid leukemia: Data from the German AML Cooperative Group (AMLCG) 1992 Trial
    • Kern W, Haferlach T, Schoch C, et al. Early blast clearance by remission induction therapy is a major independent prognostic factor for both achievement of complete remission and longterm outcome in acute myeloid leukemia: data from the German AML Cooperative Group (AMLCG) 1992 Trial. Blood. 2003;101:64-70.
    • (2003) Blood , vol.101 , pp. 64-70
    • Kern, W.1    Haferlach, T.2    Schoch, C.3
  • 23
    • 0742324488 scopus 로고    scopus 로고
    • Karyotype is an independent prognostic parameter in therapy-related acute myeloid leukemia (t-AML): An analysis of 93 patients with t-AML in comparison to 1091 patients with de novo AML
    • Schoch C, Kern W, Schnittger S, Hiddemann W, Haferlach T. Karyotype is an independent prognostic parameter in therapy-related acute myeloid leukemia (t-AML): an analysis of 93 patients with t-AML in comparison to 1091 patients with de novo AML. Leukemia. 2004;18:120-125.
    • (2004) Leukemia , vol.18 , pp. 120-125
    • Schoch, C.1    Kern, W.2    Schnittger, S.3    Hiddemann, W.4    Haferlach, T.5
  • 25
    • 0034009375 scopus 로고    scopus 로고
    • Tandem duplication of the FLT3 gene in acute lymphoblastic leukemia: A marker for the monitoring of minimal residual disease
    • Nakao M, Janssen JWG, Erz D, Serin T, Bartram CR. Tandem duplication of the FLT3 gene in acute lymphoblastic leukemia: a marker for the monitoring of minimal residual disease. Leukemia. 2000;14:522-524.
    • (2000) Leukemia , vol.14 , pp. 522-524
    • Nakao, M.1    Janssen, J.W.G.2    Erz, D.3    Serin, T.4    Bartram, C.R.5
  • 26
    • 23744479178 scopus 로고    scopus 로고
    • Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype
    • Cazzaniga G, Dell'oro MG, Mecucci C, et al. Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype. Blood. 2005;106:1419-1422.
    • (2005) Blood , vol.106 , pp. 1419-1422
    • Cazzaniga, G.1    Dell'Oro, M.G.2    Mecucci, C.3
  • 27
    • 17644416385 scopus 로고    scopus 로고
    • Nucleophosmin in acute myelogenous leukemia
    • Nakagawa M, Kameoka Y, Suzuki R. Nucleophosmin in acute myelogenous leukemia. N Engl J Med. 2005;352:1819-1820.
    • (2005) N Engl J Med , vol.352 , pp. 1819-1820
    • Nakagawa, M.1    Kameoka, Y.2    Suzuki, R.3
  • 28
    • 0037062350 scopus 로고    scopus 로고
    • PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model
    • U S A
    • Kelly LM, Kutok JL, Williams IR, et al. PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model. Proc Natl Acad Sci U S A. 2002;99:8283-8288.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 8283-8288
    • Kelly, L.M.1    Kutok, J.L.2    Williams, I.R.3
  • 30
    • 0024966024 scopus 로고
    • Major nucleolar proteins shuttle between nucleus and cytoplasm
    • Borer RA, Lehner CF, Eppenberger HM, Nigg EA. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell. 1989;56:379-390.
    • (1989) Cell , vol.56 , pp. 379-390
    • Borer, R.A.1    Lehner, C.F.2    Eppenberger, H.M.3    Nigg, E.A.4
  • 31
    • 0033556354 scopus 로고    scopus 로고
    • Detection of normal and chimeric nucleophosmin in human cells
    • Cordell JL, Pulford KA, Bigerna B, et al. Detection of normal and chimeric nucleophosmin in human cells. Blood. 1999;93:632-642.
    • (1999) Blood , vol.93 , pp. 632-642
    • Cordell, J.L.1    Pulford, K.A.2    Bigerna, B.3
  • 32
    • 0037079698 scopus 로고    scopus 로고
    • Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: Clinical value of their detection by immunocytochemistry
    • Falini B, Mason DY. Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry. Blood. 2002;99:409-426.
    • (2002) Blood , vol.99 , pp. 409-426
    • Falini, B.1    Mason, D.Y.2
  • 33
    • 0036302062 scopus 로고    scopus 로고
    • Nucleophosmin regulates the stability and transcriptional activity of p53
    • Colombo E, Marine JC, Danovi D, Falini B, Pelicci PG. Nucleophosmin regulates the stability and transcriptional activity of p53. Nat Cell Biol. 2002;4:529-533.
    • (2002) Nat Cell Biol , vol.4 , pp. 529-533
    • Colombo, E.1    Marine, J.C.2    Danovi, D.3    Falini, B.4    Pelicci, P.G.5
  • 34
    • 1642499357 scopus 로고    scopus 로고
    • Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23
    • Bertwistle D, Sugimoto M, Sherr CJ. Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23. Mol Cell Biol. 2004;24:985-996.
    • (2004) Mol Cell Biol , vol.24 , pp. 985-996
    • Bertwistle, D.1    Sugimoto, M.2    Sherr, C.J.3
  • 35
    • 0022133304 scopus 로고
    • Use of gene transfer and a novel cosmid rescue strategy to isolate transforming sequences
    • Brady G, Funk A, Mattern J, Schutz G, Brown R. Use of gene transfer and a novel cosmid rescue strategy to isolate transforming sequences. EMBO J. 1985;4:2583-2588.
    • (1985) EMBO J , vol.4 , pp. 2583-2588
    • Brady, G.1    Funk, A.2    Mattern, J.3    Schutz, G.4    Brown, R.5
  • 36
    • 0034730321 scopus 로고    scopus 로고
    • Nucleophosmin/ B23 is a target of CDK2/cyclin e in centrosome duplication
    • Okuda M, Horn HF, Tarapore P, et al. Nucleophosmin/ B23 is a target of CDK2/cyclin E in centrosome duplication. Cell. 2000;103:127-140.
    • (2000) Cell , vol.103 , pp. 127-140
    • Okuda, M.1    Horn, H.F.2    Tarapore, P.3
  • 37
    • 0033151518 scopus 로고    scopus 로고
    • A study of correlation between NPM-translocation and apoptosis in cells induced by daunomycin
    • Chan PK, Chan FY. A study of correlation between NPM-translocation and apoptosis in cells induced by daunomycin. Biochem Pharmacol. 1999;57:1265-1273.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1265-1273
    • Chan, P.K.1    Chan, F.Y.2
  • 39
    • 0344987881 scopus 로고    scopus 로고
    • A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
    • Cools J, DeAngelo DJ, Gotlib J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med. 2003;348:1201-1214.
    • (2003) N Engl J Med , vol.348 , pp. 1201-1214
    • Cools, J.1    DeAngelo, D.J.2    Gotlib, J.3
  • 40
    • 16544369516 scopus 로고    scopus 로고
    • Use of geneexpression profiling to identify prognostic subclasses in adult acute myeloid leukemia
    • Bullinger L, Dohner K, Bair E, et al. Use of geneexpression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N Engl J Med. 2004;350:1605-1616.
    • (2004) N Engl J Med , vol.350 , pp. 1605-1616
    • Bullinger, L.1    Dohner, K.2    Bair, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.