-
1
-
-
33846670732
-
Finding new treatments for diabetes-how many, how fast...how good
-
Nathan DM. Finding new treatments for diabetes-how many, how fast...how good? N Engl J Med 2007;356(5):437-40
-
(2007)
N Engl J Med
, vol.356
, Issue.5
, pp. 437-440
-
-
Nathan, D.M.1
-
2
-
-
75749095275
-
Pancreas vs. islet transplantation: A call on the future
-
Vardanyan M, Parkin E, Gruessner C, Rodriguez Rilo HL. Pancreas vs. islet transplantation: A call on the future. Curr Opin Organ Transplant 2010;15(1):124-30
-
(2010)
Curr Opin Organ Transplant
, vol.15
, Issue.1
, pp. 124-130
-
-
Vardanyan, M.1
Parkin, E.2
Gruessner, C.3
Rodriguez Rilo, H.L.4
-
3
-
-
33749070784
-
International trial of the Edmonton protocol for islet transplantation
-
Shapiro AM, Ricordi C, Hering BJ, et al. International trial of the Edmonton protocol for islet transplantation. N Engl J Med 2006;355(13):1318-30
-
(2006)
N Engl J Med
, vol.355
, Issue.13
, pp. 1318-1330
-
-
Shapiro, A.M.1
Ricordi, C.2
Hering, B.J.3
-
4
-
-
34548363807
-
The islet transplant experiment: Time for a reassessment
-
Bromberg JS, Kaplan B, Halloran PF, Robertson RP. The islet transplant experiment: Time for a reassessment. Am J Transplant 2007;7(10):2217-18
-
(2007)
Am J Transplant
, vol.7
, Issue.10
, pp. 2217-2218
-
-
Bromberg, J.S.1
Kaplan, B.2
Halloran, P.F.3
Robertson, R.P.4
-
5
-
-
70549098584
-
Are stem cells a cure for diabetes
-
McCall MD, Toso C, Baetge EE, Shapiro AMJ. Are stem cells a cure for diabetes? Clin Sci 2010;118(2):87-97
-
(2010)
Clin Sci
, vol.118
, Issue.2
, pp. 87-97
-
-
McCall, M.D.1
Toso, C.2
Baetge, E.E.3
Shapiro, A.M.J.4
-
6
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
-
Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development. Cell 2008;132(4):661-80
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
7
-
-
77953862208
-
Generating pancreatic beta-cells from embryonic stem cells by manipulating signaling pathways
-
Champeris Tsaniras S, Jones PM. Generating pancreatic beta-cells from embryonic stem cells by manipulating signaling pathways. J Endocrinol 2010;206(1):13-26
-
(2010)
J Endocrinol
, vol.206
, Issue.1
, pp. 13-26
-
-
Champeris Tsaniras, S.1
Jones, P.M.2
-
8
-
-
37249066122
-
Translational embryology: Using embryonic principles to generate pancreatic endocrine cells from embryonic stem cells
-
Spence JR, Wells JM. Translational embryology: Using embryonic principles to generate pancreatic endocrine cells from embryonic stem cells. Dev Dyn 2007;236(12):3218-27
-
(2007)
Dev Dyn
, vol.236
, Issue.12
, pp. 3218-3227
-
-
Spence, J.R.1
Wells, J.M.2
-
9
-
-
0035906902
-
Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
-
Lumelsky N, Blondel O, Laeng P, et al. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001;292(5520):1389-94
-
(2001)
Science
, vol.292
, Issue.5520
, pp. 1389-1394
-
-
Lumelsky, N.1
Blondel, O.2
Laeng, P.3
-
10
-
-
1842844430
-
Insulin expressing cells from differentiated embryonic stem cells are not beta cells
-
Sipione S, Eshpeter A, Lyon JG, et al. Insulin expressing cells from differentiated embryonic stem cells are not beta cells. Diabetologia 2004;47(3):499-508
-
(2004)
Diabetologia
, vol.47
, Issue.3
, pp. 499-508
-
-
Sipione, S.1
Eshpeter, A.2
Lyon, J.G.3
-
11
-
-
74049158251
-
Importance of quantitative analysis in the generation of insulin-expressing cells from human embryonic stem cells
-
Courtney ML, Jones PM, Burns CJ. Importance of quantitative analysis in the generation of insulin-expressing cells from human embryonic stem cells. Pancreas 2010;39(1):105-7
-
(2010)
Pancreas
, vol.39
, Issue.1
, pp. 105-107
-
-
Courtney, M.L.1
Jones, P.M.2
Burns, C.J.3
-
12
-
-
0037449573
-
Insulin staining of ES cell progeny from insulin uptake
-
Rajagopal J, Anderson WJ, Kume S, et al. Insulin staining of ES cell progeny from insulin uptake. Science 2003;299(5605):363
-
(2003)
Science
, vol.299
, Issue.5605
, pp. 363
-
-
Rajagopal, J.1
Anderson, W.J.2
Kume, S.3
-
13
-
-
4644222526
-
Artifactual insulin release from differentiated embryonic stem cells
-
Hansson M, Tonning A, Frandsen U, et al. Artifactual insulin release from differentiated embryonic stem cells. Diabetes 2004;53(10):2603-9
-
(2004)
Diabetes
, vol.53
, Issue.10
, pp. 2603-2609
-
-
Hansson, M.1
Tonning, A.2
Frandsen, U.3
-
14
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm
-
D'Amour KA, Agulnick AD, Eliazer S, et al. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol 2005;23(12):1534-41
-
(2005)
Nat Biotechnol
, vol.23
, Issue.12
, pp. 1534-1541
-
-
D'Amour, K.A.1
Agulnick, A.D.2
Eliazer, S.3
-
15
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
D'Amour KA, Bang AG, Eliazer S, et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006;24(11):1392-401
-
(2006)
Nat Biotechnol
, vol.24
, Issue.11
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
-
16
-
-
77952682209
-
Noggin retinoids and fibroblast growth factor regulate hepatic or pancreatic fate of human embryonic stem cells
-
Mfopou JK, Chen B, Mateizel I, et al. Noggin, retinoids, and fibroblast growth factor regulate hepatic or pancreatic fate of human embryonic stem cells. Gastroenterology 2010;138(7):2233-14
-
(2010)
Gastroenterology
, vol.138
, Issue.7
, pp. 2233-2214
-
-
Mfopou, J.K.1
Chen, B.2
Mateizel, I.3
-
17
-
-
77952698025
-
From embryonic stem cells to beta-cells: New hope for diabetics
-
Kaestner KH. From embryonic stem cells to beta-cells: New hope for diabetics? Gastroenterology 2010;138(7):2211-12
-
(2010)
Gastroenterology
, vol.138
, Issue.7
, pp. 2211-2212
-
-
Kaestner, K.H.1
-
18
-
-
18444407829
-
Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid
-
Shi Y, Hou L, Tang F, et al. Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid. Stem Cells 2005;23(5):656-62
-
(2005)
Stem Cells
, vol.23
, Issue.5
, pp. 656-662
-
-
Shi, Y.1
Hou, L.2
Tang, F.3
-
20
-
-
34547857040
-
Generation of insulin-producing islet-like clusters from human embryonic stem cells
-
Jiang J, Au M, Lu K, et al. Generation of insulin-producing islet-like clusters from human embryonic stem cells. Stem Cells 2007;25(8):1940-53
-
(2007)
Stem Cells
, vol.25
, Issue.8
, pp. 1940-1953
-
-
Jiang, J.1
Au, M.2
Lu, K.3
-
21
-
-
56549098457
-
In vivo characterization of transplanted human embryonic stem cell-derived pancreatic endocrine islet cells
-
Eshpeter A, Jiang J, Au M, et al. In vivo characterization of transplanted human embryonic stem cell-derived pancreatic endocrine islet cells. Cell Prolif 2008;41(6):843-58
-
(2008)
Cell Prolif
, vol.41
, Issue.6
, pp. 843-858
-
-
Eshpeter, A.1
Jiang, J.2
Au, M.3
-
22
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
Kroon E, Martinson LA, Kadoya K, et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol 2008;26(4):443-52
-
(2008)
Nat Biotechnol
, vol.26
, Issue.4
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
-
24
-
-
48949112425
-
Guided differentiation of embryonic stem cells into Pdx1-expressing regional-specific definitive endoderm
-
Shiraki N, Yoshida T, Araki K, et al. Guided differentiation of embryonic stem cells into Pdx1-expressing regional-specific definitive endoderm. Stem Cells 2008;26(4):874-85
-
(2008)
Stem Cells
, vol.26
, Issue.4
, pp. 874-885
-
-
Shiraki, N.1
Yoshida, T.2
Araki, K.3
-
25
-
-
70350637529
-
Changes in gene expression and morphology of mouse embryonic stem cells on differentiation into insulin-producing cells in vitro and in vivo
-
Naujok O, Francini F, Picton S, et al. Changes in gene expression and morphology of mouse embryonic stem cells on differentiation into insulin-producing cells in vitro and in vivo. Diabetes Metab Res Rev 2009;25(5):464-76
-
(2009)
Diabetes Metab Res Rev
, vol.25
, Issue.5
, pp. 464-476
-
-
Naujok, O.1
Francini, F.2
Picton, S.3
-
26
-
-
77958085813
-
Impact of co-culture on pancreatic differentiation of embryonic stem cells
-
Epub ahead of print
-
Banerjee I, Sharma N, Yarmush M. Impact of co-culture on pancreatic differentiation of embryonic stem cells. J Tissue Eng Regen Med 2010 [Epub ahead of print]
-
(2010)
J Tissue Eng Regen Med
-
-
Banerjee, I.1
Sharma, N.2
Yarmush, M.3
-
27
-
-
65349105337
-
Using small molecules to great effect in stem cell differentiation
-
Zaret KS. Using small molecules to great effect in stem cell differentiation. Cell Stem Cell 2009;4(5):373-4
-
(2009)
Cell Stem Cell
, vol.4
, Issue.5
, pp. 373-374
-
-
Zaret, K.S.1
-
28
-
-
75749109851
-
Converting human pluripotent stem cells into beta-cells: Recent advances and future challenges
-
Mayhew CN, Wells JM. Converting human pluripotent stem cells into beta-cells: Recent advances and future challenges. Curr Opin Organ Transplant 2010;15(1):54-60
-
(2010)
Curr Opin Organ Transplant
, vol.15
, Issue.1
, pp. 54-60
-
-
Mayhew, C.N.1
Wells, J.M.2
-
29
-
-
37749027080
-
Small molecules in stem cell self-renewal and differentiation
-
Schugar RC, Robbins PD, Deasy BM. Small molecules in stem cell self-renewal and differentiation. Gene Ther 2008;15(2):126-35
-
(2008)
Gene Ther
, vol.15
, Issue.2
, pp. 126-135
-
-
Schugar, R.C.1
Robbins, P.D.2
Deasy, B.M.3
-
30
-
-
44349152907
-
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells
-
Desbordes SC, Placantonakis DG, Ciro A, et al. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell 2008;2(6):602-12
-
(2008)
Cell Stem Cell
, vol.2
, Issue.6
, pp. 602-612
-
-
Desbordes, S.C.1
Placantonakis, D.G.2
Ciro, A.3
-
31
-
-
65349086683
-
A small molecule primes embryonic stem cells for differentiation
-
Zhu S, Wurdak H, Wang J, et al. A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell 2009;4(5):416-26
-
(2009)
Cell Stem Cell
, vol.4
, Issue.5
, pp. 416-426
-
-
Zhu, S.1
Wurdak, H.2
Wang, J.3
-
32
-
-
62949210744
-
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells
-
Borowiak M, Maehr R, Chen S, et al. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell 2009;4(4):348-58
-
(2009)
Cell Stem Cell
, vol.4
, Issue.4
, pp. 348-358
-
-
Borowiak, M.1
Maehr, R.2
Chen, S.3
-
33
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126(4):663-76
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
34
-
-
70349461184
-
Stem cells and a cure for type 1 diabetes
-
Todd JA. Stem cells and a cure for type 1 diabetes? Proc Natl Acad Sci USA 2009;106(37):15523-4
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.37
, pp. 15523-15524
-
-
Todd, J.A.1
-
35
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
Dimos JT, Rodolfa KT, Niakan KK, et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008;321(5893):1218-21
-
(2008)
Science
, vol.321
, Issue.5893
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
-
36
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert AD, Yu J, Rose FF Jr, et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009;457(7227):277-80
-
(2009)
Nature
, vol.457
, Issue.7227
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose Jr., F.F.3
-
37
-
-
70349437501
-
Generation of pluripotent stem cells from patients with type 1 diabetes
-
Maehr R, Chen S, Snitow M, et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci USA 2009;106(37):15768-73
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.37
, pp. 15768-15773
-
-
Maehr, R.1
Chen, S.2
Snitow, M.3
-
38
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner F, Hockemeyer D, Beard C, et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 2009;136(5):964-77
-
(2009)
Cell
, vol.136
, Issue.5
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
-
39
-
-
67650095306
-
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
-
Raya A, Rodriguez-Piza I, Guenechea G, et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 2009;460(7251):53-9
-
(2009)
Nature
, vol.460
, Issue.7251
, pp. 53-59
-
-
Raya, A.1
Rodriguez-Piza, I.2
Guenechea, G.3
-
40
-
-
37549030199
-
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
-
Hanna J, Wernig M, Markoulaki S, et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007;318(5858):1920-3
-
(2007)
Science
, vol.318
, Issue.5858
, pp. 1920-1923
-
-
Hanna, J.1
Wernig, M.2
Markoulaki, S.3
-
41
-
-
77953443251
-
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
-
Carvajal-Vergara X, Sevilla A, D'Souza SL, et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010;465(7299):808-12
-
(2010)
Nature
, vol.465
, Issue.7299
, pp. 808-812
-
-
Carvajal-Vergara, X.1
Sevilla, A.2
D'Souza, S.L.3
-
42
-
-
77957729169
-
Patient-specific induced pluripotent stem-cell models for Long-QT syndrome
-
Moretti A, Bellin M, Welling A, et al. Patient-specific induced pluripotent stem-cell models for Long-QT syndrome. N Engl J Med 2010;363(15):1397-409
-
N Engl J Med 2010
, vol.363
, Issue.15
, pp. 1397-1409
-
-
Moretti, A.1
Bellin, M.2
Welling, A.3
-
43
-
-
57649128308
-
Generation of insulin-secreting islet-like clusters from human skin fibroblasts
-
Tateishi K, He J, Taranova O, et al. Generation of insulin-secreting islet-like clusters from human skin fibroblasts. J Biol Chem 2008;283(46):31601-7
-
(2008)
J Biol Chem
, vol.283
, Issue.46
, pp. 31601-31607
-
-
Tateishi, K.1
He, J.2
Taranova, O.3
-
44
-
-
77955814966
-
Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic beta-like cells
-
Alipio Z, Liao W, Roemer EJ, et al. Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic beta-like cells. Proc Natl Acad Sci USA 2010;107(30):13426-31
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.30
, pp. 13426-13431
-
-
Alipio, Z.1
Liao, W.2
Roemer, E.J.3
-
45
-
-
77953095864
-
Generation of novel rat and human pluripotent stem cells by reprogramming and chemical approaches
-
Li W, Ding S. Generation of novel rat and human pluripotent stem cells by reprogramming and chemical approaches. Methods Mol Biol 2010;636:293-300
-
(2010)
Methods Mol Biol
, vol.636
, pp. 293-300
-
-
Li, W.1
Ding, S.2
-
46
-
-
70350732790
-
A chemical platform for improved induction of human iPSCs
-
Lin T, Ambasudhan R, Yuan X, et al. A chemical platform for improved induction of human iPSCs. Nat Methods 2009;6(11):805-8
-
(2009)
Nat Methods
, vol.6
, Issue.11
, pp. 805-808
-
-
Lin, T.1
Ambasudhan, R.2
Yuan, X.3
-
47
-
-
77953913401
-
Suspension culture of undifferentiated human embryonic and induced pluripotent stem cells
-
Amit M, Chebath J, Margulets V, et al. Suspension culture of undifferentiated human embryonic and induced pluripotent stem cells. Stem Cell Rev Rep 2010;6(2):248-59
-
(2010)
Stem Cell Rev Rep
, vol.6
, Issue.2
, pp. 248-259
-
-
Amit, M.1
Chebath, J.2
Margulets, V.3
-
48
-
-
70450224866
-
Induced pluripotent stem cells and reprogramming: Seeing the science through the hype
-
Belmonte JCI, Ellis J, Hochedlinger K, Yamanaka S. Induced pluripotent stem cells and reprogramming: Seeing the science through the hype. Nat Rev Genet 2009;10(12):878-83
-
(2009)
Nat Rev Genet
, vol.10
, Issue.12
, pp. 878-883
-
-
Belmonte, J.C.I.1
Ellis, J.2
Hochedlinger, K.3
Yamanaka, S.4
-
49
-
-
78650061067
-
High throughput tracking of pluripotent human embryonic stem sells with dual FRET molecular beacons
-
Epub ahead of print
-
King FW, Liszewski W, Ritner C, Bernstein HS. High throughput tracking of pluripotent human embryonic stem sells with dual FRET molecular beacons. Stem Cells Dev 2010 [Epub ahead of print]
-
(2010)
Stem Cells Dev
-
-
King, F.W.1
Liszewski, W.2
Ritner, C.3
Bernstein, H.S.4
-
50
-
-
60849091346
-
Alternative induced pluripotent stem cell characterization criteria for in vitro applications
-
Ellis J, Bruneau BG, Keller G, et al. Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell 2009;4(3):198-9
-
(2009)
Cell Stem Cell
, vol.4
, Issue.3
, pp. 198-199
-
-
Ellis, J.1
Bruneau, B.G.2
Keller, G.3
-
51
-
-
84934434640
-
Embryonic stem cell biology: Insights from molecular imaging
-
Sallam K, Wu JC. Embryonic stem cell biology: Insights from molecular imaging. Methods Mol Biol 2010;660:185-99
-
Methods Mol Biol
, vol.2010
, Issue.660
, pp. 185-199
-
-
Sallam, K.1
Wu, J.C.2
-
52
-
-
0038700553
-
Selective ablation of human embryonic stem cells expressing a suicide gene
-
Schuldiner M, Itskovitz-Eldor J, Benvenisty N. Selective ablation of human embryonic stem cells expressing a "suicide" gene. Stem Cells 2003;21(3):257-65
-
(2003)
Stem Cells
, vol.21
, Issue.3
, pp. 257-265
-
-
Schuldiner, M.1
Itskovitz-Eldor, J.2
Benvenisty, N.3
-
53
-
-
77955834772
-
Phosphorylation stabilizes Nanog by promoting its interaction with Pin1
-
Moretto-Zita M, Jin H, Shen Z, et al. Phosphorylation stabilizes Nanog by promoting its interaction with Pin1. Proc Natl Acad Sci USA 2010;107(30):13312-17
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.30
, pp. 13312-13317
-
-
Moretto-Zita, M.1
Jin, H.2
Shen, Z.3
-
54
-
-
64149118087
-
Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells
-
Zhang D, Jiang W, Liu M, et al. Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res 2009;19(4):429-38
-
(2009)
Cell Res
, vol.19
, Issue.4
, pp. 429-438
-
-
Zhang, D.1
Jiang, W.2
Liu, M.3
-
55
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
Zhou H, Wu S, Joo JY, et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009;4(5):381-4
-
(2009)
Cell Stem Cell
, vol.4
, Issue.5
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
-
56
-
-
77649275936
-
A nonviral minicircle vector for deriving human iPS cells
-
Jia F, Wilson KD, Sun N, et al. A nonviral minicircle vector for deriving human iPS cells. Nat Methods 2010;7(3):197-9
-
(2010)
Nat Methods
, vol.7
, Issue.3
, pp. 197-199
-
-
Jia, F.1
Wilson, K.D.2
Sun, N.3
-
57
-
-
12944327377
-
In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells
-
Baeyens L, De Breuck S, Lardon J, et al. In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells. Diabetologia 2005;48(1):49-57
-
(2005)
Diabetologia
, vol.48
, Issue.1
, pp. 49-57
-
-
Baeyens, L.1
De Breuck, S.2
Lardon, J.3
-
58
-
-
53549130956
-
Can beta-cells be derived from exocrine pancreas
-
Baeyens L, Bouwens L. Can beta-cells be derived from exocrine pancreas? Diabetes Obes Metab 2008;10(Suppl 4):170-8
-
(2008)
Diabetes Obes Metab
, vol.10
, Issue.SUPPL.4
, pp. 170-178
-
-
Baeyens, L.1
Bouwens, L.2
-
59
-
-
65249128642
-
Notch signaling as gatekeeper of rat acinar-to-beta-cell conversion in vitro
-
e13
-
Baeyens L, Bonne S, Bos T, et al. Notch signaling as gatekeeper of rat acinar-to-beta-cell conversion in vitro. Gastroenterology 2009;136(5):1750-60. e13
-
(2009)
Gastroenterology
, vol.136
, Issue.5
, pp. 1750-1760
-
-
Baeyens, L.1
Bonne, S.2
Bos, T.3
-
60
-
-
27244437951
-
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells
-
Minami K, Okuno M, Miyawaki K, et al. Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells. Proc Natl Acad Sci USA 2005;102(42):15116-21
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.42
, pp. 15116-15121
-
-
Minami, K.1
Okuno, M.2
Miyawaki, K.3
-
61
-
-
33845966354
-
Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes
-
Okuno M, Minami K, Okumachi A, et al. Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes. Am J Physiol Endocrinol Metab 2007;292(1):E158-65
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
, Issue.1
-
-
Okuno, M.1
Minami, K.2
Okumachi, A.3
-
63
-
-
38649125276
-
Facultative endocrine progenitor cells in the adult pancreas
-
Dor Y, Melton DA. Facultative endocrine progenitor cells in the adult pancreas. Cell 2008;132(2):183-4
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 183-184
-
-
Dor, Y.1
Melton, D.A.2
-
64
-
-
34347384162
-
Differentiation of affinity-purified human pancreatic duct cells to beta-cells
-
Yatoh S, Dodge R, Akashi T, et al. Differentiation of affinity-purified human pancreatic duct cells to beta-cells. Diabetes 2007;56(7):1802-9
-
(2007)
Diabetes
, vol.56
, Issue.7
, pp. 1802-1809
-
-
Yatoh, S.1
Dodge, R.2
Akashi, T.3
-
65
-
-
33644828800
-
Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas
-
Hao E, Tyrberg B, Itkin-Ansari P, et al. Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nat Med 2006;12(3):310-16
-
(2006)
Nat Med
, vol.12
, Issue.3
, pp. 310-316
-
-
Hao, E.1
Tyrberg, B.2
Itkin-Ansari, P.3
-
66
-
-
38749108893
-
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas
-
Xu X, D'Hoker J, Stange G, et al. Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 2008;132(2):197-207
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 197-207
-
-
Xu, X.1
D'Hoker, J.2
Stange, G.3
-
67
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou Q, Brown J, Kanarek A, et al. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008;455(7213):627-32
-
(2008)
Nature
, vol.455
, Issue.7213
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
-
68
-
-
77956004353
-
Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats
-
Li W-C, Rukstalis JM, Nishimura W, et al. Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats. J Cell Sci 2010;123(Pt 16):2792-802
-
(2010)
J Cell Sci
, vol.123
, Issue.PART 16
, pp. 2792-2802
-
-
Li, W.-C.1
Rukstalis, J.M.2
Nishimura, W.3
-
69
-
-
58149378342
-
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth
-
Inada A, Nienaber C, Katsuta H, et al. Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci USA 2008;105(50):19915-19
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.50
, pp. 19915-19919
-
-
Inada, A.1
Nienaber, C.2
Katsuta, H.3
-
70
-
-
71649092364
-
Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth
-
Solar M, Cardalda C, Houbracken I, et al. Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth. Dev Cell 2009;17(6):849-60
-
(2009)
Dev Cell
, vol.17
, Issue.6
, pp. 849-860
-
-
Solar, M.1
Cardalda, C.2
Houbracken, I.3
-
71
-
-
77950681696
-
Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas
-
Kopinke D, Murtaugh LC. Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas. BMC Dev Biol 2010;10:38
-
(2010)
BMC Dev Biol
, vol.10
, pp. 38
-
-
Kopinke, D.1
Murtaugh, L.C.2
-
72
-
-
72649101271
-
Ductal origin hypothesis of pancreatic regeneration under attack
-
Kushner JA, Weir GC, Bonner-Weir S. Ductal origin hypothesis of pancreatic regeneration under attack. Cell Metab 2010;11(1):2-3
-
(2010)
Cell Metab
, vol.11
, Issue.1
, pp. 2-3
-
-
Kushner, J.A.1
Weir, G.C.2
Bonner-Weir, S.3
-
73
-
-
77957559931
-
Ductal heterogeneity suggests a subpopulation serves as postnatal pancreatic progenitors
-
Ouziel-Yahalom L, Li WC, Straussman S, et al. Ductal heterogeneity suggests a subpopulation serves as postnatal pancreatic progenitors. Diabetes 2010;59(Suppl 1):A25
-
(2010)
Diabetes
, vol.59
, Issue.SUPPL.1
-
-
Ouziel-Yahalom, L.1
Li, W.C.2
Straussman, S.3
-
74
-
-
68149162957
-
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells
-
Collombat P, Xu X, Ravassard P, et al. The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells. Cell 2009;138(3):449-62
-
(2009)
Cell
, vol.138
, Issue.3
, pp. 449-462
-
-
Collombat, P.1
Xu, X.2
Ravassard, P.3
-
75
-
-
77958099053
-
Pancreatic beta-cell neogenesis by direct conversion from mature alpha-cells
-
Chung C-H, Hao E, Piran R, et al. Pancreatic beta-cell neogenesis by direct conversion from mature alpha-cells. Stem cells 2010;28(9):1630-8
-
(2010)
Stem cells
, vol.28
, Issue.9
, pp. 1630-1638
-
-
Chung, C.-H.1
Hao, E.2
Piran, R.3
-
76
-
-
77951611220
-
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
-
Thorel F, Nepote V, Avril I, et al. Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss. Nature 2010;464(7292):1149-54
-
(2010)
Nature
, vol.464
, Issue.7292
, pp. 1149-1154
-
-
Thorel, F.1
Nepote, V.2
Avril, I.3
-
77
-
-
57349112286
-
Generation and regeneration of cells of the liver and pancreas
-
Zaret KS, Grompe M. Generation and regeneration of cells of the liver and pancreas. Science 2008;322(5907):1490-4
-
(2008)
Science
, vol.322
, Issue.5907
, pp. 1490-1494
-
-
Zaret, K.S.1
Grompe, M.2
-
78
-
-
0034093614
-
Early mouse endoderm is patterned by soluble factors from adjacent germ layers
-
Wells JM, Melton DA. Early mouse endoderm is patterned by soluble factors from adjacent germ layers. Development 2000;127(8):1563-72
-
(2000)
Development
, vol.127
, Issue.8
, pp. 1563-1572
-
-
Wells, J.M.1
Melton, D.A.2
-
79
-
-
0033672199
-
Molecular basis of transdifferentiation of pancreas to liver
-
Shen CN, Slack JM, Tosh D. Molecular basis of transdifferentiation of pancreas to liver. Nat Cell Biol 2000;2(12):879-87
-
(2000)
Nat Cell Biol
, vol.2
, Issue.12
, pp. 879-887
-
-
Shen, C.N.1
Slack, J.M.2
Tosh, D.3
-
80
-
-
24144467428
-
Differentiation of human liver-derived, insulin-producing cells toward the beta-cell phenotype
-
Zalzman M, Anker-Kitai L, Efrat S. Differentiation of human liver-derived, insulin-producing cells toward the beta-cell phenotype. Diabetes 2005;54(9):2568-75
-
(2005)
Diabetes
, vol.54
, Issue.9
, pp. 2568-2575
-
-
Zalzman, M.1
Anker-Kitai, L.2
Efrat, S.3
-
81
-
-
70450235041
-
Exendin-4 promotes liver cell proliferation and enhances the PDX-1-induced liver to pancreas transdifferentiation process
-
Aviv V, Meivar-Levy I, Rachmut IH, et al. Exendin-4 promotes liver cell proliferation and enhances the PDX-1-induced liver to pancreas transdifferentiation process. J Biol Chem 2009;284(48):33509-20
-
(2009)
J Biol Chem
, vol.284
, Issue.48
, pp. 33509-33520
-
-
Aviv, V.1
Meivar-Levy, I.2
Rachmut, I.H.3
-
82
-
-
67651062586
-
Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells
-
Nagaya M, Katsuta H, Kaneto H, et al. Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells. J Endocrinol 2009;201(1):37-47
-
(2009)
J Endocrinol
, vol.201
, Issue.1
, pp. 37-47
-
-
Nagaya, M.1
Katsuta, H.2
Kaneto, H.3
-
83
-
-
61749094740
-
Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes
-
Yechoor V, Liu V, Espiritu C, et al. Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes. Dev Cell 2009;16(3):358-73
-
(2009)
Dev Cell
, vol.16
, Issue.3
, pp. 358-373
-
-
Yechoor, V.1
Liu, V.2
Espiritu, C.3
-
84
-
-
0242582180
-
Islet regeneration during the reversal of autoimmune diabetes in NOD mice
-
Kodama S, Kuhtreiber W, Fujimura S, et al. Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science 2003;302(5648):1223-7
-
(2003)
Science
, vol.302
, Issue.5648
, pp. 1223-1227
-
-
Kodama, S.1
Kuhtreiber, W.2
Fujimura, S.3
-
85
-
-
33747338265
-
Spleen versus pancreas: Strict control of organ interrelationship revealed by analyses of Bapx1-/- mice
-
Asayesh A, Sharpe J, Watson RP, et al. Spleen versus pancreas: Strict control of organ interrelationship revealed by analyses of Bapx1-/- mice. Genes Dev 2006;20(16):2208-13
-
(2006)
Genes Dev
, vol.20
, Issue.16
, pp. 2208-2213
-
-
Asayesh, A.1
Sharpe, J.2
Watson, R.P.3
-
86
-
-
0035049875
-
Expression of IL-5 alters bone metabolism and induces ossification of the spleen in transgenic mice
-
Macias MP, Fitzpatrick LA, Brenneise I, et al. Expression of IL-5 alters bone metabolism and induces ossification of the spleen in transgenic mice. J Clin Invest 2001;107(8):949-59
-
(2001)
J Clin Invest
, vol.107
, Issue.8
, pp. 949-959
-
-
Macias, M.P.1
Fitzpatrick, L.A.2
Brenneise, I.3
-
87
-
-
68149119072
-
Identification of splenic reservoir monocytes and their deployment to inflammatory sites
-
Swirski FK, Nahrendorf M, Etzrodt M, et al. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 2009;325(5940):612-16
-
(2009)
Science
, vol.325
, Issue.5940
, pp. 612-616
-
-
Swirski, F.K.1
Nahrendorf, M.2
Etzrodt, M.3
-
88
-
-
40549112348
-
The promise of Hox11+ stem cells of the spleen for treating autoimmune diseases
-
Lonyai A, Kodama S, Burger D, et al. The promise of Hox11+ stem cells of the spleen for treating autoimmune diseases. Horm Metab Res 2008;40(2):137-46
-
(2008)
Horm Metab Res
, vol.40
, Issue.2
, pp. 137-146
-
-
Lonyai, A.1
Kodama, S.2
Burger, D.3
-
89
-
-
33645226291
-
Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration
-
Chong AS, Shen J, Tao J, et al. Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science 2006;311(5768):1774-5
-
(2006)
Science
, vol.311
, Issue.5768
, pp. 1774-1775
-
-
Chong, A.S.1
Shen, J.2
Tao, J.3
-
90
-
-
33645221626
-
Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution
-
Nishio J, Gaglia JL, Turvey SE, et al. Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science 2006;311(5768):1775-8
-
(2006)
Science
, vol.311
, Issue.5768
, pp. 1775-1778
-
-
Nishio, J.1
Gaglia, J.L.2
Turvey, S.E.3
-
91
-
-
33645223082
-
Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells
-
Suri A, Calderon B, Esparza TJ, et al. Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells. Science 2006;311(5768):1778-80
-
(2006)
Science
, vol.311
, Issue.5768
, pp. 1778-1780
-
-
Suri, A.1
Calderon, B.2
Esparza, T.J.3
-
92
-
-
0037820427
-
Bone marrow-derived stem cells initiate pancreatic regeneration
-
Hess D, Li L, Martin M, et al. Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol 2003;21(7):763-70
-
(2003)
Nat Biotechnol
, vol.21
, Issue.7
, pp. 763-770
-
-
Hess, D.1
Li, L.2
Martin, M.3
-
93
-
-
0037364517
-
-
Ianus A, Holz GG, Theise ND, Hussain MA. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J Clin Invest 2003;111(6):843-50
-
(2003)
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J Clin Invest
, vol.111
, Issue.6
, pp. 843-850
-
-
Ianus, A.1
Holz, G.G.2
Theise, N.D.3
Hussain, M.A.4
-
94
-
-
0037183884
-
Little evidence for developmental plasticity of adult hematopoietic stem cells
-
Wagers AJ, Sherwood RI, Christensen JL, Weissman IL. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 2002;297(5590):2256-9
-
(2002)
Science
, vol.297
, Issue.5590
, pp. 2256-2259
-
-
Wagers, A.J.1
Sherwood, R.I.2
Christensen, J.L.3
Weissman, I.L.4
-
95
-
-
33644779820
-
Failure of transplanted bone marrow cells to adopt a pancreatic beta-cell fate
-
Taneera J, Rosengren A, Renstrom E, et al. Failure of transplanted bone marrow cells to adopt a pancreatic beta-cell fate. Diabetes 2006;55(2):290-6
-
(2006)
Diabetes
, vol.55
, Issue.2
, pp. 290-296
-
-
Taneera, J.1
Rosengren, A.2
Renstrom, E.3
-
96
-
-
33646152348
-
A population of very small embryonic-like (VSEL) CXCR4(+)SSEA- 1(+)Oct-4+ stem cells identified in adult bone marrow
-
Kucia M, Reca R, Campbell FR, et al. A population of very small embryonic-like (VSEL) CXCR4(+)SSEA- 1(+)Oct-4+ stem cells identified in adult bone marrow. Leukemia 2006;20(5):857-69
-
(2006)
Leukemia
, vol.20
, Issue.5
, pp. 857-869
-
-
Kucia, M.1
Reca, R.2
Campbell, F.R.3
-
97
-
-
77949888203
-
Bone marrow transplantation temporarily improves pancreatic function in streptozotocin-induced diabetes: Potential involvement of very small embryonic-like cells
-
Huang Y, Kucia M, Hussain LR, et al. Bone marrow transplantation temporarily improves pancreatic function in streptozotocin-induced diabetes: Potential involvement of very small embryonic-like cells. Transplantation 2010;89(6):677-85
-
(2010)
Transplantation
, vol.89
, Issue.6
, pp. 677-685
-
-
Huang, Y.1
Kucia, M.2
Hussain, L.R.3
-
100
-
-
76749095958
-
Immunology. Replacing an immune system gone haywire
-
Couzin-Frankel J. Immunology. Replacing an immune system gone haywire. Science 2010;327(5967):772-4
-
(2010)
Science
, vol.327
, Issue.5967
, pp. 772-774
-
-
Couzin-Frankel, J.1
-
101
-
-
77951049018
-
Autologous hematopoietic stem cell transplantation for childhood autoimmune disease
-
Milanetti F, Abinun M, Voltarelli JC, Burt RK. Autologous hematopoietic stem cell transplantation for childhood autoimmune disease. Pediatr Clin North Am 2010;57(1):239-71
-
(2010)
Pediatr Clin North Am
, vol.57
, Issue.1
, pp. 239-271
-
-
Milanetti, F.1
Abinun, M.2
Voltarelli, J.C.3
Burt, R.K.4
-
102
-
-
0032055459
-
Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the diabetes control and complications trial A randomized, controlled trial
-
The Diabetes Control and Complications Trial Research Group
-
The Diabetes Control and Complications Trial Research Group. Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. Ann Intern Med 1998;128(7):517-23
-
(1998)
Ann Intern Med
, vol.128
, Issue.7
, pp. 517-523
-
-
-
103
-
-
34247154341
-
Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus
-
Voltarelli JC, Couri CEB, Stracieri ABPL, et al. Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA 2007;297(14):1568-76
-
(2007)
JAMA
, vol.297
, Issue.14
, pp. 1568-1576
-
-
Voltarelli, J.C.1
Couri, C.E.B.2
Stracieri, A.B.P.L.3
-
104
-
-
64749084427
-
C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus
-
Couri CEB, Oliveira MCB, Stracieri ABPL, et al. C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA 2009;301(15):1573-9
-
(2009)
JAMA
, vol.301
, Issue.15
, pp. 1573-1579
-
-
Couri, C.E.B.1
Oliveira, M.C.B.2
Stracieri, A.B.P.L.3
-
105
-
-
79953702219
-
Independence of exogenous insulin following immunoablation and stem cell reconstitution in newly diagnosed diabetes type I
-
Epub ahead of print
-
Snarski E, Milczarczyk A, Torosian T, et al. Independence of exogenous insulin following immunoablation and stem cell reconstitution in newly diagnosed diabetes type I. Bone Marrow Transplant 2010 [Epub ahead of print]
-
(2010)
Bone Marrow Transplant
-
-
Snarski, E.1
Milczarczyk, A.2
Torosian, T.3
-
106
-
-
77955681255
-
Stem cell transplantation for type 1 diabetes mellitus
-
Voltarelli JC, Couri CEB. Stem cell transplantation for type 1 diabetes mellitus. Diabetol Metab Syndr 2009;1(1):4
-
(2009)
Diabetol Metab Syndr
, vol.1
, Issue.1
, pp. 4
-
-
Voltarelli, J.C.1
Couri, C.E.B.2
-
107
-
-
0023404463
-
Treatment of type 1 diabetes mellitus in non-obese diabetic mice by transplantation of allogeneic bone marrow and pancreatic tissue
-
Yasumizu R, Sugiura K, Iwai H, et al. Treatment of type 1 diabetes mellitus in non-obese diabetic mice by transplantation of allogeneic bone marrow and pancreatic tissue. Proc Natl Acad Sci USA 1987;84(18):6555-7
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.18
, pp. 6555-6557
-
-
Yasumizu, R.1
Sugiura, K.2
Iwai, H.3
-
108
-
-
0029671326
-
Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice
-
Li H, Kaufman CL, Boggs SS, et al. Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice. J Immunol 1996;156(1):380-8
-
(1996)
J Immunol
, vol.156
, Issue.1
, pp. 380-388
-
-
Li, H.1
Kaufman, C.L.2
Boggs, S.S.3
-
109
-
-
15244339538
-
Preconditioning of NOD mice with anti-CD8 mAb and costimulatory blockade enhances chimerism and tolerance and prevents diabetes, while depletion of alpha beta-TCR+ and CD4+ cells negates the effect
-
Ildstad ST, Chilton PM, Xu H, et al. Preconditioning of NOD mice with anti-CD8 mAb and costimulatory blockade enhances chimerism and tolerance and prevents diabetes, while depletion of alpha beta-TCR+ and CD4+ cells negates the effect. Blood 2005;105(6):2577-84
-
(2005)
Blood
, vol.105
, Issue.6
, pp. 2577-2584
-
-
Ildstad, S.T.1
Chilton, P.M.2
Xu, H.3
-
110
-
-
0842310011
-
Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity
-
Nikolic B, Takeuchi Y, Leykin I, et al. Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity. Diabetes 2004;53(2):376-83
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 376-383
-
-
Nikolic, B.1
Takeuchi, Y.2
Leykin, I.3
-
111
-
-
33847775017
-
Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice
-
Zhang C, Todorov I, Lin C-L, et al. Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice. Proc Natl Acad Sci USA 2007;104(7):2337-42
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.7
, pp. 2337-2342
-
-
Zhang, C.1
Todorov, I.2
Lin, C-.L.3
-
112
-
-
0038110577
-
Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes
-
Zorina TD, Subbotin VM, Bertera S, et al. Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes. Stem Cells 2003;21(4):377-88
-
(2003)
Stem Cells
, vol.21
, Issue.4
, pp. 377-388
-
-
Zorina, T.D.1
Subbotin, V.M.2
Bertera, S.3
-
113
-
-
77956375584
-
Induction of chimerism permits low-dose islet grafts in the liver or pancreas to reverse refractory autoimmune diabetes
-
Zhang C, Wang M, Racine JJ, et al. Induction of chimerism permits low-dose islet grafts in the liver or pancreas to reverse refractory autoimmune diabetes. Diabetes 2010;59(9):2228-36
-
(2010)
Diabetes
, vol.59
, Issue.9
, pp. 2228-2236
-
-
Zhang, C.1
Wang, M.2
Racine, J.J.3
-
114
-
-
0034654374
-
Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: Absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/Lt mice
-
Seung E, Iwakoshi N, Woda BA, et al. Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: Absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/Lt mice. Blood 2000;95(6):2175-82
-
(2000)
Blood
, vol.95
, Issue.6
, pp. 2175-2182
-
-
Seung, E.1
Iwakoshi, N.2
Woda, B.A.3
-
115
-
-
0037099154
-
Inducing tolerance to MHC-matched allogeneic islet grafts in diabetic NOD mice by simultaneous islet and bone marrow transplantation under nonirradiative and nonmyeloablative conditioning therapy
-
Wu T, Levay-Young B, Heuss N, et al. Inducing tolerance to MHC-matched allogeneic islet grafts in diabetic NOD mice by simultaneous islet and bone marrow transplantation under nonirradiative and nonmyeloablative conditioning therapy. Transplantation 2002;74(1):22-7
-
(2002)
Transplantation
, vol.74
, Issue.1
, pp. 22-27
-
-
Wu, T.1
Levay-Young, B.2
Heuss, N.3
-
116
-
-
0037446810
-
Nonlethal conditioning for the induction of allogeneic chimerism and tolerance to islet allografts
-
Li H, Inverardi L, Molano RD, et al. Nonlethal conditioning for the induction of allogeneic chimerism and tolerance to islet allografts. Transplantation 2003;75(7):966-70
-
(2003)
Transplantation
, vol.75
, Issue.7
, pp. 966-970
-
-
Li, H.1
Inverardi, L.2
Molano, R.D.3
-
117
-
-
44449155884
-
Combined islet and hematopoietic stem cell allotransplantation: A clinical pilot trial to induce chimerism and graft tolerance
-
Mineo D, Ricordi C, Xu X, et al. Combined islet and hematopoietic stem cell allotransplantation: A clinical pilot trial to induce chimerism and graft tolerance. Am J Transplant 2008;8(6):1262-74
-
(2008)
Am J Transplant
, vol.8
, Issue.6
, pp. 1262-1274
-
-
Mineo, D.1
Ricordi, C.2
Xu, X.3
-
118
-
-
77952805220
-
Human mesenchymal stem cells and their use in cell-based therapies
-
Motaln H, Schichor C, Lah TT. Human mesenchymal stem cells and their use in cell-based therapies. Cancer 2010;116(11):2519-30
-
(2010)
Cancer
, vol.116
, Issue.11
, pp. 2519-2530
-
-
Motaln, H.1
Schichor, C.2
Lah, T.T.3
-
119
-
-
78650057056
-
Human embryonic stem cell-derived mesenchymal progenitors: An overview
-
Hematti P. Human embryonic stem cell-derived mesenchymal progenitors: An overview. Methods Mol Biol 2011;690:163-74
-
(2011)
Methods Mol Biol
, vol.690
, pp. 163-174
-
-
Hematti, P.1
-
121
-
-
77955707890
-
Immunological and regenerative properties of cord blood stem cells
-
Francese R, Fiorina P. Immunological and regenerative properties of cord blood stem cells. Clin Immunol 2010;136(3):309-22
-
(2010)
Clin Immunol
, vol.136
, Issue.3
, pp. 309-322
-
-
Francese, R.1
Fiorina, P.2
-
122
-
-
78650060480
-
Wharton's Jelly mesenchymal stem cells as candidates for beta cells regeneration: Extending the differentiative and immunomodulatory benefits of adult mesenchymal stem cells for the treatment of type 1 diabetes
-
Epub ahead of print
-
Anzalone R, Lo Iacono M, Loria T, et al. Wharton's Jelly mesenchymal stem cells as candidates for beta cells regeneration: Extending the differentiative and immunomodulatory benefits of adult mesenchymal stem cells for the treatment of type 1 diabetes. Stem Cell Rev 2010 [Epub ahead of print]
-
(2010)
Stem Cell Rev
-
-
Anzalone, R.1
Lo Iacono, M.2
Loria, T.3
-
123
-
-
70849132807
-
Mesenchymal stem cells in hematopoietic stem cell transplantation
-
Battiwalla M, Hematti P. Mesenchymal stem cells in hematopoietic stem cell transplantation. Cytotherapy 2009;11(5):503-15
-
(2009)
Cytotherapy
, vol.11
, Issue.5
, pp. 503-515
-
-
Battiwalla, M.1
Hematti, P.2
-
124
-
-
80055108957
-
Isolation and enrichment of rat mesenchymal stem cells (MSCs) and separation of single-colony derived MSCs
-
Zhang L, Chan C. Isolation and enrichment of rat mesenchymal stem cells (MSCs) and separation of single-colony derived MSCs. J Vis Exp 2010;22(37):1852
-
(2010)
J Vis Exp
, vol.22
, Issue.37
, pp. 1852
-
-
Zhang, L.1
Chan, C.2
-
125
-
-
33747713246
-
Minimal criteria for defining multipotent mesenchymal stromal cells.The International Society for Cellular Therapy position statement
-
Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006;8(4):315-17
-
(2006)
Cytotherapy
, vol.8
, Issue.4
, pp. 315-317
-
-
Dominici, M.1
Le Blanc, K.2
Mueller, I.3
-
126
-
-
77956215701
-
Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype
-
Ghannam S, Pene J, Torcy-Moquet G, et al. Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype. J Immunol 2010;185(1):302-12
-
(2010)
J Immunol
, vol.185
, Issue.1
, pp. 302-312
-
-
Ghannam, S.1
Pene, J.2
Torcy-Moquet, G.3
-
127
-
-
33846006154
-
Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells
-
Sato K, Ozaki K, Oh I, et al. Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells. Blood 2007;109(1):228-34
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 228-234
-
-
Sato, K.1
Ozaki, K.2
Oh, I.3
-
128
-
-
30144440925
-
Human mesenchymal stem cells modulate B-cell functions
-
Corcione A, Benvenuto F, Ferretti E, et al. Human mesenchymal stem cells modulate B-cell functions. Blood 2006;107(1):367-72
-
(2006)
Blood
, vol.107
, Issue.1
, pp. 367-372
-
-
Corcione, A.1
Benvenuto, F.2
Ferretti, E.3
-
129
-
-
67649888296
-
Mesenchymal stem cells in the induction of transplantation tolerance
-
Bartholomew A, Polchert D, Szilagyi E, et al. Mesenchymal stem cells in the induction of transplantation tolerance. Transplantation 2009;87(9 Suppl):S55-7
-
(2009)
Transplantation
, vol.87
, Issue.9 SUPPL.
-
-
Bartholomew, A.1
Polchert, D.2
Szilagyi, E.3
-
130
-
-
39149115057
-
Cell and gene therapy using mesenchymal stem cells (MSCs)
-
Ozawa K, Sato K, Oh I, et al. Cell and gene therapy using mesenchymal stem cells (MSCs). J Autoimmun 2008;30(3):121-7
-
(2008)
J Autoimmun
, vol.30
, Issue.3
, pp. 121-127
-
-
Ozawa, K.1
Sato, K.2
Oh, I.3
-
131
-
-
67549119363
-
Multipotent mesenchymal stromal cells for autoimmune diseases: Teaching new dogs old tricks
-
Tyndall A, Uccelli A. Multipotent mesenchymal stromal cells for autoimmune diseases: Teaching new dogs old tricks. Bone Marrow Transplant 2009;43(11):821-8
-
(2009)
Bone Marrow Transplant
, vol.43
, Issue.11
, pp. 821-828
-
-
Tyndall, A.1
Uccelli, A.2
-
132
-
-
67349224622
-
Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells
-
Madec AM, Mallone R, Afonso G, et al. Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells. Diabetologia 2009;52(7):1391-9
-
(2009)
Diabetologia
, vol.52
, Issue.7
, pp. 1391-1399
-
-
Madec, A.M.1
Mallone, R.2
Afonso, G.3
-
133
-
-
77957605956
-
Mesenchymal stem cells enhance allogeneic islet engraftment in nonhuman primates
-
Berman DM, Willman MA, Han D, et al. Mesenchymal stem cells enhance allogeneic islet engraftment in nonhuman primates. Diabetes 2010;59(10):2558-68
-
(2010)
Diabetes
, vol.59
, Issue.10
, pp. 2558-2568
-
-
Berman, D.M.1
Willman, M.A.2
Han, D.3
-
134
-
-
36248934727
-
Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation
-
Karnieli O, Izhar-Prato Y, Bulvik S, Efrat S. Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation. Stem Cells 2007;25(11):2837-44
-
(2007)
Stem Cells
, vol.25
, Issue.11
, pp. 2837-2844
-
-
Karnieli, O.1
Izhar-Prato, Y.2
Bulvik, S.3
Efrat, S.4
-
135
-
-
77955117302
-
Differentiation of mesenchymal stem cells to insulin-producing cells and their impact on type 1 diabetic rats
-
Neshati Z, Matin MM, Bahrami AR, Moghimi A. Differentiation of mesenchymal stem cells to insulin-producing cells and their impact on type 1 diabetic rats. J Physiol Biochem 2010;66(2):181-7
-
(2010)
J Physiol Biochem
, vol.66
, Issue.2
, pp. 181-187
-
-
Neshati, Z.1
Matin, M.M.2
Bahrami, A.R.3
Moghimi, A.4
-
136
-
-
78650071907
-
Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes
-
Epub ahead of print
-
Jurewicz M, Yang S, Augello A, et al. Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes. Diabetes 2010 [Epub ahead of print]
-
(2010)
Diabetes
-
-
Jurewicz, M.1
Yang, S.2
Augello, A.3
-
137
-
-
69249196200
-
Generation of pancreatic hormone-expressing islet-like cell aggregates from murine adipose tissue-derived stem cells
-
Chandra V, G S, Phadnis S, et al. Generation of pancreatic hormone-expressing islet-like cell aggregates from murine adipose tissue-derived stem cells. Stem Cells 2009;27(8):1941-53
-
(2009)
Stem Cells
, vol.27
, Issue.8
, pp. 1941-1953
-
-
Chandra, V.G.S.1
Phadnis, S.2
-
138
-
-
69249159949
-
Insulin-secreting cells from human eyelid-derived stem cells alleviate type I diabetes in immunocompetent mice
-
Kang HM, Kim J, Park S, et al. Insulin-secreting cells from human eyelid-derived stem cells alleviate type I diabetes in immunocompetent mice. Stem Cells 2009;27(8):1999-2008
-
(2009)
Stem Cells
, vol.27
, Issue.8
, pp. 1999-2008
-
-
Kang, H.M.1
Kim, J.2
Park, S.3
-
139
-
-
33751232671
-
Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice
-
Lee RH, Seo MJ, Reger RL, et al. Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice. Proc Natl Acad Sci USA 2006;103(46):17438-43
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.46
, pp. 17438-17443
-
-
Lee, R.H.1
Seo, M.J.2
Reger, R.L.3
-
140
-
-
70249122431
-
Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes
-
Fiorina P, Jurewicz M, Augello A, et al. Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes. J Immunol 2009;183(2):993-1004
-
(2009)
J Immunol
, vol.183
, Issue.2
, pp. 993-1004
-
-
Fiorina, P.1
Jurewicz, M.2
Augello, A.3
-
141
-
-
75349108811
-
Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function
-
Sordi V, Melzi R, Mercalli A, et al. Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function. Stem Cells 2010;28(1):140-51
-
(2010)
Stem Cells
, vol.28
, Issue.1
, pp. 140-151
-
-
Sordi, V.1
Melzi, R.2
Mercalli, A.3
-
142
-
-
71749091230
-
Influence of human allogenic bone marrow and cord blood-derived mesenchymal stem cell secreting trophic factors on ATP (adenosine-5- triphosphate)/ADP (adenosine-5-diphosphate) ratio and insulin secretory function of isolated human islets from cadaveric donor
-
Park KS, Kim YS, Kim JH, et al. Influence of human allogenic bone marrow and cord blood-derived mesenchymal stem cell secreting trophic factors on ATP (adenosine-5-triphosphate)/ADP (adenosine-5-diphosphate) ratio and insulin secretory function of isolated human islets from cadaveric donor. Transplant Proc 2009;41(9):3813-18
-
(2009)
Transplant Proc
, vol.41
, Issue.9
, pp. 3813-3818
-
-
Park, K.S.1
Kim, Y.S.2
Kim, J.H.3
-
143
-
-
68049125093
-
Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9
-
Ding Y, Xu D, Feng G, et al. Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9. Diabetes 2009;58(8):1797-806
-
(2009)
Diabetes
, vol.58
, Issue.8
, pp. 1797-1806
-
-
Ding, Y.1
Xu, D.2
Feng, G.3
-
144
-
-
59149098948
-
Autologous bone marrow-derived rat mesenchymal stem cells promote PDX-1 and insulin expression in the islets, alter T cell cytokine pattern and preserve regulatory T cells in the periphery and induce sustained normoglycemia
-
Boumaza I, Srinivasan S, Witt WT, et al. Autologous bone marrow-derived rat mesenchymal stem cells promote PDX-1 and insulin expression in the islets, alter T cell cytokine pattern and preserve regulatory T cells in the periphery and induce sustained normoglycemia. J Autoimmun 2009;32(1):33-42
-
(2009)
J Autoimmun
, vol.32
, Issue.1
, pp. 33-42
-
-
Boumaza, I.1
Srinivasan, S.2
Witt, W.T.3
-
145
-
-
67249166267
-
Bone marrow-derived mesenchymal stem cells improve islet graft function in diabetic rats
-
Figliuzzi M, Cornolti R, Perico N, et al. Bone marrow-derived mesenchymal stem cells improve islet graft function in diabetic rats. Transplant Proc 2009;41(5):1797-800
-
(2009)
Transplant Proc
, vol.41
, Issue.5
, pp. 1797-1800
-
-
Figliuzzi, M.1
Cornolti, R.2
Perico, N.3
-
146
-
-
77954084921
-
Mesenchymal stem cell and islet co-transplantation promotes graft revascularization and function
-
Ito T, Itakura S, Todorov I, et al. Mesenchymal stem cell and islet co-transplantation promotes graft revascularization and function. Transplantation 2010;89(12):1438-45
-
(2010)
Transplantation
, vol.89
, Issue.12
, pp. 1438-1445
-
-
Ito, T.1
Itakura, S.2
Todorov, I.3
-
147
-
-
62649093531
-
Chemicals turn human embryonic stem cells towards beta cells
-
Yang YP, Wright C. Chemicals turn human embryonic stem cells towards beta cells. Nat Chem Biol 2009;5(4):195-6
-
(2009)
Nat Chem Biol
, vol.5
, Issue.4
, pp. 195-196
-
-
Yang, Y.P.1
Wright, C.2
-
148
-
-
77953159822
-
Human iPS cell-based therapy: Considerations before clinical applications
-
Sun N, Longaker MT, Wu JC. Human iPS cell-based therapy: Considerations before clinical applications. Cell Cycle 2010;9(5):880-5
-
(2010)
Cell Cycle
, vol.9
, Issue.5
, pp. 880-885
-
-
Sun, N.1
Longaker, M.T.2
Wu, J.C.3
-
149
-
-
40449141341
-
Marked differences in differentiation propensity among human embryonic stem cell lines
-
Osafune K, Caron L, Borowiak M, et al. Marked differences in differentiation propensity among human embryonic stem cell lines. Nat Biotechnol 2008;26(3):313-15
-
(2008)
Nat Biotechnol
, vol.26
, Issue.3
, pp. 313-315
-
-
Osafune, K.1
Caron, L.2
Borowiak, M.3
-
150
-
-
0033961920
-
Human embryonic stem cell and embryonic germ cell lines
-
Thomson JA, Odorico JS. Human embryonic stem cell and embryonic germ cell lines. Trends Biotechnol 2000;18(2):53-7
-
(2000)
Trends Biotechnol
, vol.18
, Issue.2
, pp. 53-57
-
-
Thomson, J.A.1
Odorico, J.S.2
-
151
-
-
70350050399
-
Human parthenogenetic embryonic stem cells: One potential resource for cell therapy
-
Hao J, Zhu W, Sheng C, et al. Human parthenogenetic embryonic stem cells: One potential resource for cell therapy. Sci China C Life Sci 2009;52(7):599-602
-
(2009)
Sci China C Life Sci
, vol.52
, Issue.7
, pp. 599-602
-
-
Hao, J.1
Zhu, W.2
Sheng, C.3
-
152
-
-
77952957930
-
In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells
-
e4
-
Goodrich AD, Ersek A, Varain NM, et al. In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells. Exp Hematol 2010;38(6):516-25.e4
-
(2010)
Exp Hematol
, vol.38
, Issue.6
, pp. 516-525
-
-
Goodrich, A.D.1
Ersek, A.2
Varain, N.M.3
-
153
-
-
40949088116
-
Hematopoietic mixed chimerism derived from allogeneic embryonic stem cells prevents autoimmune diabetes mellitus in NOD mice
-
Verda L, Kim DA, Ikehara S, et al. Hematopoietic mixed chimerism derived from allogeneic embryonic stem cells prevents autoimmune diabetes mellitus in NOD mice. Stem Cells 2008;26(2):381-6
-
(2008)
Stem Cells
, vol.26
, Issue.2
, pp. 381-386
-
-
Verda, L.1
Kim, D.A.2
Ikehara, S.3
-
154
-
-
67649814155
-
Human embryonic stem cell-derived mesenchymal progenitors-Potential in regenerative medicine
-
Karlsson C, Emanuelsson K, Wessberg F, et al. Human embryonic stem cell-derived mesenchymal progenitors-Potential in regenerative medicine. Stem Cell Res 2009;3(1):39-50
-
(2009)
Stem Cell Res
, vol.3
, Issue.1
, pp. 39-50
-
-
Karlsson, C.1
Emanuelsson, K.2
Wessberg, F.3
-
155
-
-
77956895183
-
Embryonic stem cells: Court decision a threat to science itself
-
Cash G. Embryonic stem cells: Court decision a threat to science itself. Nature 2010;467(7313):271
-
(2010)
Nature
, vol.467
, Issue.7313
, pp. 271
-
-
Cash, G.1
-
156
-
-
77956320527
-
Stem-cell work thrown into limbo
-
Wadman M. Stem-cell work thrown into limbo. Nature 2010;467(7311):12-3
-
(2010)
Nature
, vol.467
, Issue.7311
, pp. 12-13
-
-
Wadman, M.1
-
157
-
-
56749173982
-
New ISSCR guidelines underscore major principles for responsible translational stem cell research
-
Hyun I, Lindvall O, Ahrlund-Richter L, et al. New ISSCR guidelines underscore major principles for responsible translational stem cell research. Cell Stem Cell 2008;3(6):607-9
-
(2008)
Cell Stem Cell
, vol.3
, Issue.6
, pp. 607-609
-
-
Hyun, I.1
Lindvall, O.2
Ahrlund-Richter, L.3
-
158
-
-
77952226356
-
Survey details stem cell clinics ahead of regulatory approval
-
Dolgin E. Survey details stem cell clinics ahead of regulatory approval. Nat Med 2010;16(5):495
-
(2010)
Nat Med
, vol.16
, Issue.5
, pp. 495
-
-
Dolgin, E.1
-
159
-
-
78049320362
-
Residual insulin production and pancreatic beta cell turnover after 50 years of diabetes: Joslin Medalist Study
-
Keenan HA, Sun JK, Levine J, et al. Residual insulin production and pancreatic beta cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes 2010;58(11):2846-53
-
(2010)
Diabetes
, vol.58
, Issue.11
, pp. 2846-2853
-
-
Keenan, H.A.1
Sun, J.K.2
Levine, J.3
|