-
1
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
The Diabetes Control and Complications Trial Research Group
-
The Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 329, 977-986
-
(1993)
N. Engl. J. Med
, vol.329
, pp. 977-986
-
-
-
2
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
-
UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study (UKPDS) Group (1998) Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352, 837-853
-
(1998)
Lancet
, vol.352
, pp. 837-853
-
-
-
3
-
-
0014093712
-
Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy
-
Kelly, W. D., Lillehei, R. C., Merkel, F. K., Idezuki, Y. and Goetz, F. C. (1967) Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy. Surgery 61, 827-837
-
(1967)
Surgery
, vol.61
, pp. 827-837
-
-
Kelly, W.D.1
Lillehei, R.C.2
Merkel, F.K.3
Idezuki, Y.4
Goetz, F.C.5
-
4
-
-
22244456740
-
Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004
-
Gruessner, A. C. and Sutherland, D. E. (2005) Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004. Clin. Transplant. 19, 433-455
-
(2005)
Clin. Transplant
, vol.19
, pp. 433-455
-
-
Gruessner, A.C.1
Sutherland, D.E.2
-
5
-
-
0015386234
-
Transplantation of intact pancreatic islets in rats
-
Ballinger, W. F. and Lacy, P. E. (1972) Transplantation of intact pancreatic islets in rats. Surgery 72, 175-186
-
(1972)
Surgery
, vol.72
, pp. 175-186
-
-
Ballinger, W.F.1
Lacy, P.E.2
-
6
-
-
0025269474
-
Insulin independence after islet transplantation into type I diabetic patient
-
Scharp, D.W., Lacy, P. E., Santiago, J. V., McCullough, C. S., Weide, L. G., Falqui, L., Marchetti, P., Gingerich, R. L., Jaffe, A. S., Cryer, P. E. et al. (1990) Insulin independence after islet transplantation into type I diabetic patient. Diabetes 39, 515-518
-
(1990)
Diabetes
, vol.39
, pp. 515-518
-
-
Scharp, D.W.1
Lacy, P.E.2
Santiago, J.V.3
McCullough, C.S.4
Weide, L.G.5
Falqui, L.6
Marchetti, P.7
Gingerich, R.L.8
Jaffe, A.S.9
Cryer, P.E.10
-
7
-
-
0024532672
-
Automated islet isolation from human pancreas
-
Ricordi, C., Lacy, P. E. and Scharp, D. W. (1989) Automated islet isolation from human pancreas. Diabetes 38 (Suppl. 1), 140-142
-
(1989)
Diabetes
, vol.38
, Issue.SUPPL. 1
, pp. 140-142
-
-
Ricordi, C.1
Lacy, P.E.2
Scharp, D.W.3
-
8
-
-
0034721255
-
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
-
Shapiro, A. M. J., Lakey, J. R., Ryan, E. A., Korbutt, G. S., Toth, E., Warnock, G. L., Kneteman, N. M. and Rajotte, R. V. (2000) Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 343, 230-238
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 230-238
-
-
Shapiro, A.M.J.1
Lakey, J.R.2
Ryan, E.A.3
Korbutt, G.S.4
Toth, E.5
Warnock, G.L.6
Kneteman, N.M.7
Rajotte, R.V.8
-
9
-
-
33749070784
-
International trial of the Edmonton protocol for islet transplantation
-
Shapiro, A. M. J., Ricordi, C., Hering, B. J., Auchincloss, H., Lindblad, R., Robertson, R. P., Secchi, A., Brendel, M. D., Berney, T., Brennan, D. C. et al. (2006) International trial of the Edmonton protocol for islet transplantation. N. Engl. J. Med. 355, 1318-1330
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 1318-1330
-
-
Shapiro, A.M.J.1
Ricordi, C.2
Hering, B.J.3
Auchincloss, H.4
Lindblad, R.5
Robertson, R.P.6
Secchi, A.7
Brendel, M.D.8
Berney, T.9
Brennan, D.C.10
-
10
-
-
21344462346
-
Five-year follow-up after clinical islet transplantation
-
Ryan, E. A., Paty, B.W., Senior, P. A., Bigam, D., Alfadhli, E., Kneteman, N. M., Lakey, J. R. and Shapiro, A. M. J. (2005) Five-year follow-up after clinical islet transplantation. Diabetes 54, 2060-2069
-
(2005)
Diabetes
, vol.54
, pp. 2060-2069
-
-
Ryan, E.A.1
Paty, B.W.2
Senior, P.A.3
Bigam, D.4
Alfadhli, E.5
Kneteman, N.M.6
Lakey, J.R.7
Shapiro, A.M.J.8
-
11
-
-
0036303015
-
Successful islet transplantation: Continued insulin reserve provides long-term glycemic control
-
Ryan, E. A., Lakey, J. R., Paty, B.W., Imes, S., Korbutt, G. S., Kneteman, N. M., Bigam, D., Rajotte, R. V. and Shapiro, A. M. J. (2002) Successful islet transplantation: continued insulin reserve provides long-term glycemic control. Diabetes 51, 2148-2157
-
(2002)
Diabetes
, vol.51
, pp. 2148-2157
-
-
Ryan, E.A.1
Lakey, J.R.2
Paty, B.W.3
Imes, S.4
Korbutt, G.S.5
Kneteman, N.M.6
Bigam, D.7
Rajotte, R.V.8
Shapiro, A.M.J.9
-
12
-
-
1842527586
-
Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation
-
Ryan, E. A., Shandro, T., Green, K., Paty, B.W., Senior, P. A., Bigam, D., Shapiro, A. M. J. and Vantyghem, M. C. (2004) Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation. Diabetes 53, 955-962
-
(2004)
Diabetes
, vol.53
, pp. 955-962
-
-
Ryan, E.A.1
Shandro, T.2
Green, K.3
Paty, B.W.4
Senior, P.A.5
Bigam, D.6
Shapiro, A.M.J.7
Vantyghem, M.C.8
-
13
-
-
34548738327
-
Quality of life after islet transplant: Impact of the number of islet infusions and metabolic outcome
-
Toso, C., Shapiro, A. M. J., Bowker, S., Dinyari, P., Paty, B., Ryan, E. A., Senior, P. and Johnson, J. A. (2007) Quality of life after islet transplant: impact of the number of islet infusions and metabolic outcome. Transplantation 84, 664-666
-
(2007)
Transplantation
, vol.84
, pp. 664-666
-
-
Toso, C.1
Shapiro, A.M.J.2
Bowker, S.3
Dinyari, P.4
Paty, B.5
Ryan, E.A.6
Senior, P.7
Johnson, J.A.8
-
14
-
-
0043033101
-
Estimating the number of potential organ donors in the United States
-
Sheehy, E., Conrad, S. L., Brigham, L. E., Luskin, R., Weber, P., Eakin, M., Schkade, L. and Hunsicker, L. (2003) Estimating the number of potential organ donors in the United States. N. Engl. J. Med. 349, 667-674
-
(2003)
N. Engl. J. Med
, vol.349
, pp. 667-674
-
-
Sheehy, E.1
Conrad, S.L.2
Brigham, L.E.3
Luskin, R.4
Weber, P.5
Eakin, M.6
Schkade, L.7
Hunsicker, L.8
-
15
-
-
33845961662
-
Follow-up study of the first successful living donor islet transplantation
-
Matsumoto, S., Okitsu, T., Iwanaga, Y., Noguchi, H., Nagata, H., Yonekawa, Y., Liu, X., Kamiya, H., Ueda, M., Hatanaka, N. et al. (2006) Follow-up study of the first successful living donor islet transplantation. Transplantation 82, 1629-1633
-
(2006)
Transplantation
, vol.82
, pp. 1629-1633
-
-
Matsumoto, S.1
Okitsu, T.2
Iwanaga, Y.3
Noguchi, H.4
Nagata, H.5
Yonekawa, Y.6
Liu, X.7
Kamiya, H.8
Ueda, M.9
Hatanaka, N.10
-
16
-
-
21044455869
-
-
Matsumoto, S., Okitsu, T., Iwanaga, Y., Noguchi, H., Nagata, H., Yonekawa, Y., Yamada, Y., Fukuda, K., Tsukiyama, K., Suzuki, H. et al. (2005) Insulin independence after living-donor distal pancreatectomy and islet allotransplantation. Lancet 365, 1642-1644
-
Matsumoto, S., Okitsu, T., Iwanaga, Y., Noguchi, H., Nagata, H., Yonekawa, Y., Yamada, Y., Fukuda, K., Tsukiyama, K., Suzuki, H. et al. (2005) Insulin independence after living-donor distal pancreatectomy and islet allotransplantation. Lancet 365, 1642-1644
-
-
-
-
17
-
-
15944383017
-
Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets
-
Kin, T., Korbutt, G. S., Kobayashi, T., Dufour, J. M. and Rajotte, R. V. (2005) Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets. Diabetes 54, 1032-1039
-
(2005)
Diabetes
, vol.54
, pp. 1032-1039
-
-
Kin, T.1
Korbutt, G.S.2
Kobayashi, T.3
Dufour, J.M.4
Rajotte, R.V.5
-
18
-
-
33644829825
-
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways
-
Cardona, K., Korbutt, G. S., Milas, Z., Lyon, J., Cano, J., Jiang, W., Bello-Laborn, H., Hacquoil, B., Strobert, E., Gangappa, S. et al. (2006) Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways. Nat. Med. 12, 304-306
-
(2006)
Nat. Med
, vol.12
, pp. 304-306
-
-
Cardona, K.1
Korbutt, G.S.2
Milas, Z.3
Lyon, J.4
Cano, J.5
Jiang, W.6
Bello-Laborn, H.7
Hacquoil, B.8
Strobert, E.9
Gangappa, S.10
-
19
-
-
60549101092
-
Prolonged survival of microencapsulated neonatal porcine islet xenografts in immune-competent mice without antirejection therapy
-
Kobayashi, T., Arefanian, H., Harb, G., Tredget, E. B., Rajotte, R. V., Korbutt, G. S. and Rayat, G. R. (2008) Prolonged survival of microencapsulated neonatal porcine islet xenografts in immune-competent mice without antirejection therapy. Cell Transplant. 17, 1243-1256
-
(2008)
Cell Transplant
, vol.17
, pp. 1243-1256
-
-
Kobayashi, T.1
Arefanian, H.2
Harb, G.3
Tredget, E.B.4
Rajotte, R.V.5
Korbutt, G.S.6
Rayat, G.R.7
-
20
-
-
0000062301
-
Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells
-
Becker, A. J., McCulloch, E. and Till, J. E. (1963) Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature 197, 452-454
-
(1963)
Nature
, vol.197
, pp. 452-454
-
-
Becker, A.J.1
McCulloch, E.2
Till, J.E.3
-
21
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans, M. J. and Kaufman, M. H. (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
22
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin, G. R. (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. U.S.A. 78, 7634-7638
-
(1981)
Proc. Natl. Acad. Sci. U.S.A
, vol.78
, pp. 7634-7638
-
-
Martin, G.R.1
-
23
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S. and Jones, J. M. (1998) Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
24
-
-
40149085423
-
Successful unmanipulated peripheral blood progenitor cell transplantation from an HLA haploidentical 2-locus-mismatched mother in a thalassemic patient with primary graft failure after transplantation of bone marrow and cord blood from unrelated donors
-
Jaing, T. H., Sun, C. F., Lee, W. I., Wen, Y. C., Yang, C. P. and Hung, I. J. (2008) Successful unmanipulated peripheral blood progenitor cell transplantation from an HLA haploidentical 2-locus-mismatched mother in a thalassemic patient with primary graft failure after transplantation of bone marrow and cord blood from unrelated donors. Pediatr. Transplant. 12, 232-234
-
(2008)
Pediatr. Transplant
, vol.12
, pp. 232-234
-
-
Jaing, T.H.1
Sun, C.F.2
Lee, W.I.3
Wen, Y.C.4
Yang, C.P.5
Hung, I.J.6
-
25
-
-
33846120651
-
Isolation of amniotic stem cell lines with potential for therapy
-
De Coppi, P., Bartsch, Jr, G., Siddiqui, M. M., Xu, T., Santos, C. C., Perin, L., Mostoslavsky, G., Serre, A. C., Snyder, E. Y., Yoo, J. J. et al. (2007) Isolation of amniotic stem cell lines with potential for therapy. Nat. Biotechnol. 25, 100-106
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 100-106
-
-
De Coppi, P.1
Bartsch Jr, G.2
Siddiqui, M.M.3
Xu, T.4
Santos, C.C.5
Perin, L.6
Mostoslavsky, G.7
Serre, A.C.8
Snyder, E.Y.9
Yoo, J.J.10
-
26
-
-
56749160139
-
Generation of pluripotent stem cells from adult human testis
-
Conrad, S., Renninger, M., Hennenlotter, J., Wiesner, T., Just, L., Bonin, M., Aicher, W., Buhring, H. J., Mattheus, U., Mack, A. et al. (2008) Generation of pluripotent stem cells from adult human testis. Nature 456, 344-349
-
(2008)
Nature
, vol.456
, pp. 344-349
-
-
Conrad, S.1
Renninger, M.2
Hennenlotter, J.3
Wiesner, T.4
Just, L.5
Bonin, M.6
Aicher, W.7
Buhring, H.J.8
Mattheus, U.9
Mack, A.10
-
27
-
-
13944250206
-
Adult stem cell therapy in stroke
-
Haas, S., Weidner, N. and Winkler, J. (2005) Adult stem cell therapy in stroke. Curr. Opin. Neurol. 18, 59-64
-
(2005)
Curr. Opin. Neurol
, vol.18
, pp. 59-64
-
-
Haas, S.1
Weidner, N.2
Winkler, J.3
-
28
-
-
38949181979
-
Curing blindness with stem cells: Hope, reality, and challenges
-
Adler, R. (2008) Curing blindness with stem cells: hope, reality, and challenges. Adv. Exp. Med. Biol. 613, 3-20
-
(2008)
Adv. Exp. Med. Biol
, vol.613
, pp. 3-20
-
-
Adler, R.1
-
29
-
-
38049029702
-
The role of stem cells in the post-MI patient
-
Meyer, G. P., Wollert, K. C. and Drexler, H. (2007) The role of stem cells in the post-MI patient. Curr. Heart Failure Rep. 4, 198-203
-
(2007)
Curr. Heart Failure Rep
, vol.4
, pp. 198-203
-
-
Meyer, G.P.1
Wollert, K.C.2
Drexler, H.3
-
30
-
-
20044375937
-
A single course of anti-CD3 monoclonal antibody hOKT3γ 1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
-
Herold, K. C., Gitelman, S. E., Masharani, U., Hagopian, W., Bisikirska, B., Donaldson, D., Rother, K., Diamond, B., Harlan, D. M. and Bluestone, J. A. (2005) A single course of anti-CD3 monoclonal antibody hOKT3γ 1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54, 1763-1769
-
(2005)
Diabetes
, vol.54
, pp. 1763-1769
-
-
Herold, K.C.1
Gitelman, S.E.2
Masharani, U.3
Hagopian, W.4
Bisikirska, B.5
Donaldson, D.6
Rother, K.7
Diamond, B.8
Harlan, D.M.9
Bluestone, J.A.10
-
31
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
Herold, K. C., Hagopian, W., Auger, J. A., Poumian-Ruiz, E., Taylor, L., Donaldson, D., Gitelman, S. E., Harlan, D. M., Xu, D., Zivin, R. A. and Bluestone, J. A. (2002) Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N. Engl. J. Med. 346, 1692-1698
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 1692-1698
-
-
Herold, K.C.1
Hagopian, W.2
Auger, J.A.3
Poumian-Ruiz, E.4
Taylor, L.5
Donaldson, D.6
Gitelman, S.E.7
Harlan, D.M.8
Xu, D.9
Zivin, R.A.10
Bluestone, J.A.11
-
32
-
-
20044386299
-
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties
-
Larsen, C. P., Pearson, T. C., Adams, A. B., Tso, P., Shirasugi, N., Strobertm, E., Anderson, D., Cowan, S., Price, K., Naemura, J. et al. (2005) Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. Am. J. Transplant. 5, 443-453
-
(2005)
Am. J. Transplant
, vol.5
, pp. 443-453
-
-
Larsen, C.P.1
Pearson, T.C.2
Adams, A.B.3
Tso, P.4
Shirasugi, N.5
Strobertm, E.6
Anderson, D.7
Cowan, S.8
Price, K.9
Naemura, J.10
-
33
-
-
23944502334
-
Costimulation blockade with belatacept in renal transplantation
-
Vincenti, F., Larsen, C., Durrbach, A., Wekerle, T., Nashan, B., Blancho, G., Lang, P., Grinyo, J., Halloran, P. F., Solez, K. et al. (2005) Costimulation blockade with belatacept in renal transplantation. N. Engl. J. Med. 353, 770-781
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 770-781
-
-
Vincenti, F.1
Larsen, C.2
Durrbach, A.3
Wekerle, T.4
Nashan, B.5
Blancho, G.6
Lang, P.7
Grinyo, J.8
Halloran, P.F.9
Solez, K.10
-
34
-
-
0027449197
-
A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development
-
Bonner-Weir, S., Baxter, L. A., Schuppin, G. T. and Smith, F. E. (1993) A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development. Diabetes 42, 1715-1720
-
(1993)
Diabetes
, vol.42
, pp. 1715-1720
-
-
Bonner-Weir, S.1
Baxter, L.A.2
Schuppin, G.T.3
Smith, F.E.4
-
35
-
-
0034608816
-
In vitro cultivation of human islets from expanded ductal tissue
-
Bonner-Weir, S., Taneja, M., Weir, G. C., Tatarkiewicz, K., Song, K. H., Sharma, A. and O'Neil, J. J. (2000) In vitro cultivation of human islets from expanded ductal tissue. Proc. Natl. Acad. Sci. U.S.A. 97, 7999-8004
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 7999-8004
-
-
Bonner-Weir, S.1
Taneja, M.2
Weir, G.C.3
Tatarkiewicz, K.4
Song, K.H.5
Sharma, A.6
O'Neil, J.J.7
-
36
-
-
0043268785
-
Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture
-
Gao, R., Ustinov, J., Pulkkinen, M. A., Lundin, K., Korsgren, O. and Otonkoski, T. (2003) Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture. Diabetes 52, 2007-2015
-
(2003)
Diabetes
, vol.52
, pp. 2007-2015
-
-
Gao, R.1
Ustinov, J.2
Pulkkinen, M.A.3
Lundin, K.4
Korsgren, O.5
Otonkoski, T.6
-
37
-
-
0033815611
-
Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: Further evidence for pluripotent pancreatic stem cells in humans
-
Gmyr, V., Kerr-Conte, J., Belaich, S., Vandewalle, B., Leteurtre, E., Vantyghem, M. C., Lecomte-Houcke, M., Proye, C., Lefebvre, J. and Pattou, F. (2000) Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans. Diabetes 49, 1671-1680
-
(2000)
Diabetes
, vol.49
, pp. 1671-1680
-
-
Gmyr, V.1
Kerr-Conte, J.2
Belaich, S.3
Vandewalle, B.4
Leteurtre, E.5
Vantyghem, M.C.6
Lecomte-Houcke, M.7
Proye, C.8
Lefebvre, J.9
Pattou, F.10
-
38
-
-
4444320484
-
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages
-
Seaberg, R. M., Smukler, S. R., Kieffer, T. J., Enikolopov, G., Asghar, Z., Wheeler, M. B., Korbutt, G. and van der Kooy, D. (2004) Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages. Nat. Biotechnol. 22, 1115-1124
-
(2004)
Nat. Biotechnol
, vol.22
, pp. 1115-1124
-
-
Seaberg, R.M.1
Smukler, S.R.2
Kieffer, T.J.3
Enikolopov, G.4
Asghar, Z.5
Wheeler, M.B.6
Korbutt, G.7
van der Kooy, D.8
-
39
-
-
0035119871
-
Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
-
Zulewski, H., Abraham, E. J., Gerlach,M. J., Daniel, P. B., Moritz, W., Muller, B., Vallejo, M., Thomas, M. K. and Habener, J. F. (2001) Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 50, 521-533
-
(2001)
Diabetes
, vol.50
, pp. 521-533
-
-
Zulewski, H.1
Abraham, E.J.2
Gerlach, M.J.3
Daniel, P.B.4
Moritz, W.5
Muller, B.6
Vallejo, M.7
Thomas, M.K.8
Habener, J.F.9
-
40
-
-
33646825627
-
Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets
-
Eberhardt, M., Salmon, P., von Mach, M. A., Hengstler, J. G., Brulport, M., Linscheid, P., Seboek, D., Oberholzer, J., Barbero, A., Martin, I. et al. (2006) Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets. Biochem. Biophys. Res. Commun. 345, 1167-1176
-
(2006)
Biochem. Biophys. Res. Commun
, vol.345
, pp. 1167-1176
-
-
Eberhardt, M.1
Salmon, P.2
von Mach, M.A.3
Hengstler, J.G.4
Brulport, M.5
Linscheid, P.6
Seboek, D.7
Oberholzer, J.8
Barbero, A.9
Martin, I.10
-
41
-
-
2342510386
-
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
-
Dor, Y., Brown, J., Martinez, O. I. and Melton, D. A. (2004) Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429, 41-46
-
(2004)
Nature
, vol.429
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
42
-
-
38749108893
-
β Cells can be generated from endogenous progenitors in injured adult mouse pancreas
-
Xu, X., D'Hoker, J., Stangé, G., Bonné, S., De Leu, N., Xiao, X., Van de Casteele, M., Mellitzer, G., Ling, Z., Pipeleers, D. et al. (2008) β Cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 132, 197-207
-
(2008)
Cell
, vol.132
, pp. 197-207
-
-
Xu, X.1
D'Hoker, J.2
Stangé, G.3
Bonné, S.4
De Leu, N.5
Xiao, X.6
Van de Casteele, M.7
Mellitzer, G.8
Ling, Z.9
Pipeleers, D.10
-
43
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelqvist, A., Li, H., Sommer, L., Beatus, P., Anderson, D. J., Honjo, T., Hrabe de Angelis, M., Lendahl, U. and Edlund, H. (1999) Notch signalling controls pancreatic cell differentiation. Nature 400, 877-881
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Anderson, D.J.5
Honjo, T.6
Hrabe de Angelis, M.7
Lendahl, U.8
Edlund, H.9
-
44
-
-
0036340074
-
+ cells are islet progenitors and are distinct from duct progenitors
-
+ cells are islet progenitors and are distinct from duct progenitors. Development 129, 2447-2457
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
45
-
-
12944327377
-
In vitro generation of insulin-producing β cells from adult exocrine pancreatic cells
-
Baeyens, L., De Breuck, S., Lardon, J., Mfopou, J. K., Rooman, I. and Bouwens, L. (2005) In vitro generation of insulin-producing β cells from adult exocrine pancreatic cells. Diabetologia 48, 49-57
-
(2005)
Diabetologia
, vol.48
, pp. 49-57
-
-
Baeyens, L.1
De Breuck, S.2
Lardon, J.3
Mfopou, J.K.4
Rooman, I.5
Bouwens, L.6
-
46
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
-
Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J. and Melton, D. A. (2008) In vivo reprogramming of adult pancreatic exocrine cells to β-cells. Nature 455, 627-632
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
-
47
-
-
0035805055
-
Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell
-
Krause, D. S., Theise, N. D., Collector, M. I., Henegariu, O., Hwang, S., Gardner, R., Neutzel, S. and Sharkis, S. J. (2001) Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 105, 369-377
-
(2001)
Cell
, vol.105
, pp. 369-377
-
-
Krause, D.S.1
Theise, N.D.2
Collector, M.I.3
Henegariu, O.4
Hwang, S.5
Gardner, R.6
Neutzel, S.7
Sharkis, S.J.8
-
48
-
-
0034531907
-
From marrow to brain: Expression of neuronal phenotypes in adult mice
-
Brazelton, T. R., Rossi, F. M., Keshet, G. I. and Blau, H. M. (2000) From marrow to brain: expression of neuronal phenotypes in adult mice. Science 290, 1775-1779
-
(2000)
Science
, vol.290
, pp. 1775-1779
-
-
Brazelton, T.R.1
Rossi, F.M.2
Keshet, G.I.3
Blau, H.M.4
-
49
-
-
0037019337
-
Pluripotency of mesenchymal stem cells derived from adult marrow
-
Jiang, Y., Jahagirdar, B. N., Reinhardt, R. L., Schwartz, R. E., Keene, C. D., Ortiz-Gonzalez, X. R., Reyes, M., Lenvik, T., Lund, T., Blackstad, M. et al. (2002) Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418, 41-49
-
(2002)
Nature
, vol.418
, pp. 41-49
-
-
Jiang, Y.1
Jahagirdar, B.N.2
Reinhardt, R.L.3
Schwartz, R.E.4
Keene, C.D.5
Ortiz-Gonzalez, X.R.6
Reyes, M.7
Lenvik, T.8
Lund, T.9
Blackstad, M.10
-
50
-
-
0033694301
-
Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
-
Lagasse, E., Connors, H., Al-Dhalimy, M., Reitsma, M., Dohse, M., Osborne, L., Wang, X., Finegold, M., Weissman, I. L. and Grompe, M. (2000) Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat. Med. 6, 1229-1234
-
(2000)
Nat. Med
, vol.6
, pp. 1229-1234
-
-
Lagasse, E.1
Connors, H.2
Al-Dhalimy, M.3
Reitsma, M.4
Dohse, M.5
Osborne, L.6
Wang, X.7
Finegold, M.8
Weissman, I.L.9
Grompe, M.10
-
51
-
-
0037364517
-
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion
-
Ianus, A., Holz, G. G., Theise, N. D. and Hussain, M. A. (2003) In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J. Clin. Invest. 111, 843-850
-
(2003)
J. Clin. Invest
, vol.111
, pp. 843-850
-
-
Ianus, A.1
Holz, G.G.2
Theise, N.D.3
Hussain, M.A.4
-
52
-
-
0037820427
-
Bone marrow-derived stem cells initiate pancreatic regeneration
-
Hess, D., Li, L., Martin, M., Sakano, S., Hill, D., Strutt, B., Thyssen, S., Gray, D. A. and Bhatia, M. (2003) Bone marrow-derived stem cells initiate pancreatic regeneration. Nat. Biotechnol. 21, 763-770
-
(2003)
Nat. Biotechnol
, vol.21
, pp. 763-770
-
-
Hess, D.1
Li, L.2
Martin, M.3
Sakano, S.4
Hill, D.5
Strutt, B.6
Thyssen, S.7
Gray, D.A.8
Bhatia, M.9
-
53
-
-
10744233909
-
Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic β cells
-
Choi, J. B., Uchino, H., Azuma, K., Iwashita, N., Tanaka, Y., Mochizuki, H., Migita, M., Shimada, T., Kawamori, R. and Watada, H. (2003) Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic β cells. Diabetologia 46, 1366-1374
-
(2003)
Diabetologia
, vol.46
, pp. 1366-1374
-
-
Choi, J.B.1
Uchino, H.2
Azuma, K.3
Iwashita, N.4
Tanaka, Y.5
Mochizuki, H.6
Migita, M.7
Shimada, T.8
Kawamori, R.9
Watada, H.10
-
54
-
-
0346099384
-
Recruitment of bone marrow-derived endothelial cells to sites of pancreatic β-cell injury
-
Mathews, V., Hanson, P. T., Ford, E., Fujita, J., Polonsky, K. S. and Graubert, T. A. (2004) Recruitment of bone marrow-derived endothelial cells to sites of pancreatic β-cell injury. Diabetes 53, 91-98
-
(2004)
Diabetes
, vol.53
, pp. 91-98
-
-
Mathews, V.1
Hanson, P.T.2
Ford, E.3
Fujita, J.4
Polonsky, K.S.5
Graubert, T.A.6
-
55
-
-
0242582180
-
Islet regeneration during the reversal of autoimmune diabetes in NOD mice
-
Kodama, S., Kuhtreiber, W., Fujimura, S., Dale, E. A. and Faustman, D. L. (2003) Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science 302, 1223-1227
-
(2003)
Science
, vol.302
, pp. 1223-1227
-
-
Kodama, S.1
Kuhtreiber, W.2
Fujimura, S.3
Dale, E.A.4
Faustman, D.L.5
-
56
-
-
33645221626
-
Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution
-
Nishio, J., Gaglia, J. L., Turvey, S. E., Campbell, C., Benoist, C. and Mathis, D. (2006) Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science 311, 1775-1778
-
(2006)
Science
, vol.311
, pp. 1775-1778
-
-
Nishio, J.1
Gaglia, J.L.2
Turvey, S.E.3
Campbell, C.4
Benoist, C.5
Mathis, D.6
-
57
-
-
33645226291
-
Reversal of diabetes in non-obese diabetic mice without spleen cell-derived β cell regeneration
-
Chong, A. S., Shen, J., Tao, J., Yin, D., Kuznetsov, A., Hara, M. and Philipson, L. H. (2006) Reversal of diabetes in non-obese diabetic mice without spleen cell-derived β cell regeneration. Science 311, 1774-1775
-
(2006)
Science
, vol.311
, pp. 1774-1775
-
-
Chong, A.S.1
Shen, J.2
Tao, J.3
Yin, D.4
Kuznetsov, A.5
Hara, M.6
Philipson, L.H.7
-
58
-
-
33645223082
-
Immunological reversal of autoimmune diabetes without hematopoietic replacement of β cells
-
Suri, A., Calderon, B., Esparza, T. J., Frederick, K., Bittner, P. and Unanue, E. R. (2006) Immunological reversal of autoimmune diabetes without hematopoietic replacement of β cells. Science 311, 1778-1780
-
(2006)
Science
, vol.311
, pp. 1778-1780
-
-
Suri, A.1
Calderon, B.2
Esparza, T.J.3
Frederick, K.4
Bittner, P.5
Unanue, E.R.6
-
59
-
-
0025293535
-
Prevention of type I diabetes in NOD mice by adjuvant immunotherapy
-
Sadelain, M. W., Qin, H. Y., Lauzon, J. and Singh, B. (1990) Prevention of type I diabetes in NOD mice by adjuvant immunotherapy. Diabetes 39, 583-589
-
(1990)
Diabetes
, vol.39
, pp. 583-589
-
-
Sadelain, M.W.1
Qin, H.Y.2
Lauzon, J.3
Singh, B.4
-
60
-
-
27144462791
-
Human cord blood - derived cells generate insulin-producing cells in vivo
-
Yoshida, S., Ishikawa, F., Kawano, N., Shimoda, K., Nagafuchi, S., Shimoda, S., Yasukawa, M., Kanemaru, T., Ishibashi, H., Shultz, L. D. and Harada, M. (2005) Human cord blood - derived cells generate insulin-producing cells in vivo. Stem Cells 23, 1409-1416
-
(2005)
Stem Cells
, vol.23
, pp. 1409-1416
-
-
Yoshida, S.1
Ishikawa, F.2
Kawano, N.3
Shimoda, K.4
Nagafuchi, S.5
Shimoda, S.6
Yasukawa, M.7
Kanemaru, T.8
Ishibashi, H.9
Shultz, L.D.10
Harada, M.11
-
61
-
-
0035906902
-
Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
-
Lumelsky, N., Blondel, O., Laeng, P., Velasco, I., Ravin, R. and McKay, R. (2001) Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 292, 1389-1394
-
(2001)
Science
, vol.292
, pp. 1389-1394
-
-
Lumelsky, N.1
Blondel, O.2
Laeng, P.3
Velasco, I.4
Ravin, R.5
McKay, R.6
-
62
-
-
34249019166
-
Directed engineering of umbilical cord blood stem cells to produce C-peptide and insulin
-
Denner, L., Bodenburg, Y., Zhao, J. G., Howe, M., Cappo, J., Tilton, R. G., Copland, J. A., Forraz, N., McGuckin, C. and Urban, R. (2007) Directed engineering of umbilical cord blood stem cells to produce C-peptide and insulin. Cell Prolif. 40, 367-380
-
(2007)
Cell Prolif
, vol.40
, pp. 367-380
-
-
Denner, L.1
Bodenburg, Y.2
Zhao, J.G.3
Howe, M.4
Cappo, J.5
Tilton, R.G.6
Copland, J.A.7
Forraz, N.8
McGuckin, C.9
Urban, R.10
-
63
-
-
43049176667
-
Autologous umbilical cord blood infusion for type 1 diabetes
-
Haller, M. J., Viener, H. L., Wasserfall, C., Brusko, T., Atkinson, M. A. and Schatz, D. A. (2008) Autologous umbilical cord blood infusion for type 1 diabetes. Exp. Hematol. 36, 710-715
-
(2008)
Exp. Hematol
, vol.36
, pp. 710-715
-
-
Haller, M.J.1
Viener, H.L.2
Wasserfall, C.3
Brusko, T.4
Atkinson, M.A.5
Schatz, D.A.6
-
64
-
-
64749084427
-
C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus
-
Couri, C. E., Oliveira, M. C., Stracieri, A. B., Moraes, D. A., Pieroni, F., Barros, G. M., Madeira, M. I., Malmegrim, K. C., Foss-Freitas, M. C., Simoes, B. P. et al. (2009) C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA, J. Am. Med. Assoc. 301, 1573-1579
-
(2009)
JAMA, J. Am. Med. Assoc
, vol.301
, pp. 1573-1579
-
-
Couri, C.E.1
Oliveira, M.C.2
Stracieri, A.B.3
Moraes, D.A.4
Pieroni, F.5
Barros, G.M.6
Madeira, M.I.7
Malmegrim, K.C.8
Foss-Freitas, M.C.9
Simoes, B.P.10
-
65
-
-
62549123720
-
Combined treatment of intrapancreatic autologous bone marrow stem cells and hyperbaric oxygen in type 2 diabetes mellitus
-
Estrada, E. J., Valacchi, F., Nicora, E., Brieva, S., Esteve, C., Echevarria, L., Froud, T., Bernetti, K., Cayetano, S. M., Velazquez, O. et al. (2008) Combined treatment of intrapancreatic autologous bone marrow stem cells and hyperbaric oxygen in type 2 diabetes mellitus. Cell Transplant. 17, 1295-1304
-
(2008)
Cell Transplant
, vol.17
, pp. 1295-1304
-
-
Estrada, E.J.1
Valacchi, F.2
Nicora, E.3
Brieva, S.4
Esteve, C.5
Echevarria, L.6
Froud, T.7
Bernetti, K.8
Cayetano, S.M.9
Velazquez, O.10
-
66
-
-
0031938718
-
Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat
-
Petersen, B. E., Goff, J. P., Greenberger, J. S. and Michalopoulos, G. K. (1998) Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat. Hepatology 27, 433-445
-
(1998)
Hepatology
, vol.27
, pp. 433-445
-
-
Petersen, B.E.1
Goff, J.P.2
Greenberger, J.S.3
Michalopoulos, G.K.4
-
67
-
-
0034068602
-
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
-
Ferber, S., Halkin, A., Cohen, H., Ber, I., Einav, Y., Goldberg, I., Barshack, I., Seijffers, R., Kopolovic, J., Kaiser, N. and Karasik, A. (2000) Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat. Med. 6, 568-572
-
(2000)
Nat. Med
, vol.6
, pp. 568-572
-
-
Ferber, S.1
Halkin, A.2
Cohen, H.3
Ber, I.4
Einav, Y.5
Goldberg, I.6
Barshack, I.7
Seijffers, R.8
Kopolovic, J.9
Kaiser, N.10
Karasik, A.11
-
68
-
-
0037062515
-
In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells
-
Yang, L., Li, S., Hatch, H., Ahrens, K., Cornelius, J. G., Petersen, B. E. and Peck, A. B. (2002) In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells. Proc. Natl. Acad. Sci. U.S.A. 99, 8078-8083
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 8078-8083
-
-
Yang, L.1
Li, S.2
Hatch, H.3
Ahrens, K.4
Cornelius, J.G.5
Petersen, B.E.6
Peck, A.B.7
-
69
-
-
0041856137
-
Functional, persistent, and extended liver to pancreas transdifferentiation
-
Ber, I., Shternhall, K., Perl, S., Ohanuna, Z., Goldberg, I., Barshack, I., Benvenisti-Zarum, L., Meivar-Levy, I. and Ferber, S. (2003) Functional, persistent, and extended liver to pancreas transdifferentiation. J. Biol. Chem. 278, 31950-31957
-
(2003)
J. Biol. Chem
, vol.278
, pp. 31950-31957
-
-
Ber, I.1
Shternhall, K.2
Perl, S.3
Ohanuna, Z.4
Goldberg, I.5
Barshack, I.6
Benvenisti-Zarum, L.7
Meivar-Levy, I.8
Ferber, S.9
-
70
-
-
0038413922
-
NeuroD-β cellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice
-
Kojima, H., Fujimiya, M., Matsumura, K., Younan, P., Imaeda, H., Maeda, M. and Chan, L. (2003) NeuroD-β cellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice. Nat. Med. 9, 596-603
-
(2003)
Nat. Med
, vol.9
, pp. 596-603
-
-
Kojima, H.1
Fujimiya, M.2
Matsumura, K.3
Younan, P.4
Imaeda, H.5
Maeda, M.6
Chan, L.7
-
71
-
-
0038472015
-
Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells
-
Zalzman, M., Gupta, S., Giri, R. K., Berkovich, I., Sappal, B. S., Karnieli, O., Zern, M. A., Fleischer, N. and Efrat, S. (2003) Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells. Proc. Natl. Acad. Sci. U.S.A. 100, 7253-7258
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 7253-7258
-
-
Zalzman, M.1
Gupta, S.2
Giri, R.K.3
Berkovich, I.4
Sappal, B.S.5
Karnieli, O.6
Zern, M.A.7
Fleischer, N.8
Efrat, S.9
-
72
-
-
9444255761
-
High glucose is necessary for complete maturation of Pdx1-VP16-expressing hepatic cells into functional insulin-producing cells
-
Cao, L. Z., Tang, D. Q., Horb, M. E., Li, S. W. and Yang, L. J. (2004) High glucose is necessary for complete maturation of Pdx1-VP16-expressing hepatic cells into functional insulin-producing cells. Diabetes 53, 3168-3178
-
(2004)
Diabetes
, vol.53
, pp. 3168-3178
-
-
Cao, L.Z.1
Tang, D.Q.2
Horb, M.E.3
Li, S.W.4
Yang, L.J.5
-
73
-
-
15944417831
-
PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance
-
Kaneto, H., Nakatani, Y., Miyatsuka, T., Matsuoka, T. A., Matsuhisa, M., Hori, M. and Yamasaki, Y. (2005) PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Diabetes 54, 1009-1022
-
(2005)
Diabetes
, vol.54
, pp. 1009-1022
-
-
Kaneto, H.1
Nakatani, Y.2
Miyatsuka, T.3
Matsuoka, T.A.4
Matsuhisa, M.5
Hori, M.6
Yamasaki, Y.7
-
74
-
-
17644381301
-
A crucial role of MafA as a novel therapeutic target for diabetes
-
Kaneto, H., Matsuoka, T. A., Nakatani, Y., Miyatsuka, T., Matsuhisa, M., Hori, M. and Yamasaki, Y. (2005) A crucial role of MafA as a novel therapeutic target for diabetes. J. Biol. Chem. 280, 15047-15052
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15047-15052
-
-
Kaneto, H.1
Matsuoka, T.A.2
Nakatani, Y.3
Miyatsuka, T.4
Matsuhisa, M.5
Hori, M.6
Yamasaki, Y.7
-
75
-
-
34250349195
-
Streptozotocin-induced diabetes can be reversed by hepatic oval cell activation through hepatic transdifferentiation and pancreatic islet regeneration
-
Kim, S., Shin, J. S., Kim, H. J., Fisher, R. C., Lee, M. J. and Kim, C.W. (2007) Streptozotocin-induced diabetes can be reversed by hepatic oval cell activation through hepatic transdifferentiation and pancreatic islet regeneration. Lab. Invest. 87, 702-712
-
(2007)
Lab. Invest
, vol.87
, pp. 702-712
-
-
Kim, S.1
Shin, J.S.2
Kim, H.J.3
Fisher, R.C.4
Lee, M.J.5
Kim, C.W.6
-
76
-
-
20344394437
-
Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells
-
Sapir, T., Shternhall, K., Meivar-Levy, I., Blumenfeld, T., Cohen, H., Skutelsky, E., Eventov-Friedman, S., Barshack, I., Goldberg, I., Pri-Chen, S. et al. (2005) Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells. Proc. Natl. Acad. Sci. U.S.A. 102, 7964-7969
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 7964-7969
-
-
Sapir, T.1
Shternhall, K.2
Meivar-Levy, I.3
Blumenfeld, T.4
Cohen, H.5
Skutelsky, E.6
Eventov-Friedman, S.7
Barshack, I.8
Goldberg, I.9
Pri-Chen, S.10
-
77
-
-
0036328180
-
PDX-1 induces differentiation of intestinal epithelioid IEC-6 into insulin-producing cells
-
Yoshida, S., Kajimoto, Y., Yasuda, T., Watada, H., Fujitani, Y., Kosaka, H., Gotow, T., Miyatsuka, T., Umayahara, Y., Yamasaki, Y. and Hori, M. (2002) PDX-1 induces differentiation of intestinal epithelioid IEC-6 into insulin-producing cells. Diabetes 51, 2505-2513
-
(2002)
Diabetes
, vol.51
, pp. 2505-2513
-
-
Yoshida, S.1
Kajimoto, Y.2
Yasuda, T.3
Watada, H.4
Fujitani, Y.5
Kosaka, H.6
Gotow, T.7
Miyatsuka, T.8
Umayahara, Y.9
Yamasaki, Y.10
Hori, M.11
-
78
-
-
0036312398
-
Combined expression of pancreatic duodenal homeobox 1 and islet factor 1 induces immature enterocytes to produce insulin
-
Kojima, H., Nakamura, T., Fujita, Y., Kishi, A., Fujimiya, M., Yamada, S., Kudo, M., Nishio, Y., Maegawa, H., Haneda, M. et al. (2002) Combined expression of pancreatic duodenal homeobox 1 and islet factor 1 induces immature enterocytes to produce insulin. Diabetes 51, 1398-1408
-
(2002)
Diabetes
, vol.51
, pp. 1398-1408
-
-
Kojima, H.1
Nakamura, T.2
Fujita, Y.3
Kishi, A.4
Fujimiya, M.5
Yamada, S.6
Kudo, M.7
Nishio, Y.8
Maegawa, H.9
Haneda, M.10
-
79
-
-
0037628628
-
Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells
-
Suzuki, A., Nakauchi, H. and Taniguchi, H. (2003) Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells. Proc. Natl. Acad. Sci. U.S.A. 100, 5034-5039
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 5034-5039
-
-
Suzuki, A.1
Nakauchi, H.2
Taniguchi, H.3
-
80
-
-
0038461880
-
Salivary gland progenitor cells induced by duct ligation differentiate into hepatic and pancreatic lineages
-
Okumura, K., Nakamura, K., Hisatomi, Y., Nagano, K., Tanaka, Y., Terada, K., Sugiyama, T., Umeyama, K., Matsumoto, K., Yamamoto, T. and Endo, F. (2003) Salivary gland progenitor cells induced by duct ligation differentiate into hepatic and pancreatic lineages. Hepatology 38, 104-113
-
(2003)
Hepatology
, vol.38
, pp. 104-113
-
-
Okumura, K.1
Nakamura, K.2
Hisatomi, Y.3
Nagano, K.4
Tanaka, Y.5
Terada, K.6
Sugiyama, T.7
Umeyama, K.8
Matsumoto, K.9
Yamamoto, T.10
Endo, F.11
-
81
-
-
32344451060
-
Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells
-
Timper, K., Seboek, D., Eberhardt, M., Linscheid, P., Christ-Crain, M., Keller, U., Muller, B. and Zulewski, H. (2006) Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells. Biochem. Biophys. Res. Commun. 341, 1135-1140
-
(2006)
Biochem. Biophys. Res. Commun
, vol.341
, pp. 1135-1140
-
-
Timper, K.1
Seboek, D.2
Eberhardt, M.3
Linscheid, P.4
Christ-Crain, M.5
Keller, U.6
Muller, B.7
Zulewski, H.8
-
82
-
-
0033979603
-
Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice
-
Soria, B., Roche, E., Berna, G., Leon-Quinto, T., Reig, J. A. and Martin, F. (2000) Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 49, 157-162
-
(2000)
Diabetes
, vol.49
, pp. 157-162
-
-
Soria, B.1
Roche, E.2
Berna, G.3
Leon-Quinto, T.4
Reig, J.A.5
Martin, F.6
-
83
-
-
0037058934
-
Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells
-
Hori, Y., Rulifson, I. C., Tsai, B. C., Heit, J. J., Cahoy, J. D. and Kim, S. K. (2002) Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 99, 16105-16110
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 16105-16110
-
-
Hori, Y.1
Rulifson, I.C.2
Tsai, B.C.3
Heit, J.J.4
Cahoy, J.D.5
Kim, S.K.6
-
84
-
-
0042767581
-
Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: An in vitro model to study islet differentiation
-
Kahan, B. W., Jacobson, L. M., Hullett, D. A., Ochoada, J. M., Oberley, T. D., Lang, K. M. and Odorico, J. S. (2003) Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: an in vitro model to study islet differentiation. Diabetes 52, 2016-2024
-
(2003)
Diabetes
, vol.52
, pp. 2016-2024
-
-
Kahan, B.W.1
Jacobson, L.M.2
Hullett, D.A.3
Ochoada, J.M.4
Oberley, T.D.5
Lang, K.M.6
Odorico, J.S.7
-
85
-
-
13144281727
-
Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells
-
Blyszczuk, P., Asbrand, C., Rozzo, A., Kania, G., St-Onge, L., Rupnik, M. and Wobus, A. M. (2004) Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells. Int. J. Dev. Biol. 48, 1095-1104
-
(2004)
Int. J. Dev. Biol
, vol.48
, pp. 1095-1104
-
-
Blyszczuk, P.1
Asbrand, C.2
Rozzo, A.3
Kania, G.4
St-Onge, L.5
Rupnik, M.6
Wobus, A.M.7
-
86
-
-
0037417958
-
Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells
-
Blyszczuk, P., Czyz, J., Kania, G., Wagner, M., Roll, U., St-Onge, L. and Wobus, A. M. (2003) Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc. Natl. Acad. Sci. U.S.A. 100, 998-1003
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 998-1003
-
-
Blyszczuk, P.1
Czyz, J.2
Kania, G.3
Wagner, M.4
Roll, U.5
St-Onge, L.6
Wobus, A.M.7
-
87
-
-
1842527497
-
Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells
-
Miyazaki, S., Yamato, E. and Miyazaki, J. (2004) Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells. Diabetes 53, 1030-1037
-
(2004)
Diabetes
, vol.53
, pp. 1030-1037
-
-
Miyazaki, S.1
Yamato, E.2
Miyazaki, J.3
-
88
-
-
4544310572
-
In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells
-
Leon-Quinto, T., Jones, J., Skoudy, A., Burcin, M. and Soria, B. (2004) In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells. Diabetologia 47, 1442-1451
-
(2004)
Diabetologia
, vol.47
, pp. 1442-1451
-
-
Leon-Quinto, T.1
Jones, J.2
Skoudy, A.3
Burcin, M.4
Soria, B.5
-
89
-
-
0035434048
-
Insulin production by human embryonic stem cells
-
Assady, S., Maor, G., Amit, M., Itskovitz-Eldor, J., Skorecki, K. L. and Tzukerman, M. (2001) Insulin production by human embryonic stem cells. Diabetes 50, 1691-1697
-
(2001)
Diabetes
, vol.50
, pp. 1691-1697
-
-
Assady, S.1
Maor, G.2
Amit, M.3
Itskovitz-Eldor, J.4
Skorecki, K.L.5
Tzukerman, M.6
-
90
-
-
2942615532
-
Differentiation of human embryonic stem cells into insulin-producing clusters
-
Segev, H., Fishman, B., Ziskind, A., Shulman, M. and Itskovitz-Eldor, J. (2004) Differentiation of human embryonic stem cells into insulin-producing clusters. Stem Cells 22, 265-274
-
(2004)
Stem Cells
, vol.22
, pp. 265-274
-
-
Segev, H.1
Fishman, B.2
Ziskind, A.3
Shulman, M.4
Itskovitz-Eldor, J.5
-
91
-
-
19344362213
-
Differentiation of insulin-producing cells from human neural progenitor cells
-
Hori, Y., Gu, X., Xie, X. and Kim, S. K. (2005) Differentiation of insulin-producing cells from human neural progenitor cells. PLoS Med. 2, e103
-
(2005)
PLoS Med
, vol.2
-
-
Hori, Y.1
Gu, X.2
Xie, X.3
Kim, S.K.4
-
92
-
-
4644222526
-
Artifactual insulin release from differentiated embryonic stem cells
-
Hansson, M., Tonning, A., Frandsen, U., Petri, A., Rajagopal, J., Englund, M. C., Heller, R. S., Hakansson, J., Fleckner, J., Skold, H. N. et al. (2004) Artifactual insulin release from differentiated embryonic stem cells. Diabetes 53, 2603-2609
-
(2004)
Diabetes
, vol.53
, pp. 2603-2609
-
-
Hansson, M.1
Tonning, A.2
Frandsen, U.3
Petri, A.4
Rajagopal, J.5
Englund, M.C.6
Heller, R.S.7
Hakansson, J.8
Fleckner, J.9
Skold, H.N.10
-
93
-
-
0037449573
-
Insulin staining of ES cell progeny from insulin uptake
-
Rajagopal, J., Anderson, W. J., Kume, S., Martinez, O. I. and Melton, D. A. (2003) Insulin staining of ES cell progeny from insulin uptake. Science 299, 363
-
(2003)
Science
, vol.299
, pp. 363
-
-
Rajagopal, J.1
Anderson, W.J.2
Kume, S.3
Martinez, O.I.4
Melton, D.A.5
-
94
-
-
1842844430
-
Insulin expressing cells from differentiated embryonic stem cells are not β cells
-
Sipione, S., Eshpeter, A., Lyon, J. G., Korbutt, G. S. and Bleackley, R. C. (2004) Insulin expressing cells from differentiated embryonic stem cells are not β cells. Diabetologia 47, 499-508
-
(2004)
Diabetologia
, vol.47
, pp. 499-508
-
-
Sipione, S.1
Eshpeter, A.2
Lyon, J.G.3
Korbutt, G.S.4
Bleackley, R.C.5
-
95
-
-
0027436779
-
Gastrulation in the mouse embryo: Ultrastructural and molecular aspects of germ layer morphogenesis
-
Tam, P. P., Williams, E. A. and Chan, W. Y. (1993) Gastrulation in the mouse embryo: ultrastructural and molecular aspects of germ layer morphogenesis. Microsc. Res. Tech. 26, 301-328
-
(1993)
Microsc. Res. Tech
, vol.26
, pp. 301-328
-
-
Tam, P.P.1
Williams, E.A.2
Chan, W.Y.3
-
97
-
-
0037213587
-
Gene expression cascades in pancreatic development
-
Wilson, M. E., Scheel, D. and German, M. S. (2003) Gene expression cascades in pancreatic development. Mech. Dev. 120, 65-80
-
(2003)
Mech. Dev
, vol.120
, pp. 65-80
-
-
Wilson, M.E.1
Scheel, D.2
German, M.S.3
-
98
-
-
2342424743
-
Development of definitive endoderm from embryonic stem cells in culture
-
Kubo, A., Shinozaki, K., Shannon, J. M., Kouskoff, V., Kennedy, M., Woo, S., Fehling, H. J. and Keller, G. (2004) Development of definitive endoderm from embryonic stem cells in culture. Development 131, 1651-1662
-
(2004)
Development
, vol.131
, pp. 1651-1662
-
-
Kubo, A.1
Shinozaki, K.2
Shannon, J.M.3
Kouskoff, V.4
Kennedy, M.5
Woo, S.6
Fehling, H.J.7
Keller, G.8
-
99
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm
-
D'Amour, K. A., Agulnick, A. D., Eliazer, S., Kelly, O. G., Kroon, E. and Baetge, E. E. (2005) Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat. Biotechnol. 23, 1534-1541
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 1534-1541
-
-
D'Amour, K.A.1
Agulnick, A.D.2
Eliazer, S.3
Kelly, O.G.4
Kroon, E.5
Baetge, E.E.6
-
100
-
-
33750846133
-
-
'Amour, K. A., Bang, A. G., Eliazer, S., Kelly, O. G., Agulnick, A. D., Smart, N. G., Moorman, M. A., Kroon, E., Carpenter, M. K. and Baetge, E. E. (2006) Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 24, 1392-1401
-
'Amour, K. A., Bang, A. G., Eliazer, S., Kelly, O. G., Agulnick, A. D., Smart, N. G., Moorman, M. A., Kroon, E., Carpenter, M. K. and Baetge, E. E. (2006) Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 24, 1392-1401
-
-
-
-
101
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
Kroon, E., Martinson, L. A., Kadoya, K., Bang, A. G., Kelly, O. G., Eliazer, S., Young, H., Richardson, M., Smart, N. G., Cunningham, J. et al. (2008) Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat. Biotechnol. 26, 443-452
-
(2008)
Nat. Biotechnol
, vol.26
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
Bang, A.G.4
Kelly, O.G.5
Eliazer, S.6
Young, H.7
Richardson, M.8
Smart, N.G.9
Cunningham, J.10
-
102
-
-
0035199577
-
Blood glucose normalization upon transplantation of human embryonic pancreas into β-cell-deficient SCID mice
-
Castaing, M., Peault, B., Basmaciogullari, A., Casal, I., Czernichow, P. and Scharfmann, R. (2001) Blood glucose normalization upon transplantation of human embryonic pancreas into β-cell-deficient SCID mice. Diabetologia 44, 2066-2076
-
(2001)
Diabetologia
, vol.44
, pp. 2066-2076
-
-
Castaing, M.1
Peault, B.2
Basmaciogullari, A.3
Casal, I.4
Czernichow, P.5
Scharfmann, R.6
-
103
-
-
34548425734
-
Normal relationship of β- and non-β-cells not needed for successful islet transplantation
-
King, A. J., Fernandes, J. R., Hollister-Lock, J., Nienaber, C. E., Bonner-Weir, S. and Weir, G. C. (2007) Normal relationship of β- and non-β-cells not needed for successful islet transplantation. Diabetes 56, 2312-2318
-
(2007)
Diabetes
, vol.56
, pp. 2312-2318
-
-
King, A.J.1
Fernandes, J.R.2
Hollister-Lock, J.3
Nienaber, C.E.4
Bonner-Weir, S.5
Weir, G.C.6
-
104
-
-
0034042959
-
Islet growth and development in the adult
-
Bonner-Weir, S. (2000) Islet growth and development in the adult. J. Mol. Endocrinol. 24, 297-302
-
(2000)
J. Mol. Endocrinol
, vol.24
, pp. 297-302
-
-
Bonner-Weir, S.1
-
105
-
-
0031044215
-
Viable offspring derived from fetal and adult mammalian cells
-
Wilmut, I., Schnieke, A. E., McWhir, J., Kind, A. J. and Campbell, K. H. (1997) Viable offspring derived from fetal and adult mammalian cells. Nature 385, 810-813
-
(1997)
Nature
, vol.385
, pp. 810-813
-
-
Wilmut, I.1
Schnieke, A.E.2
McWhir, J.3
Kind, A.J.4
Campbell, K.H.5
-
106
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu, J., Vodyanik, M. A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J. L., Tian, S., Nie, J., Jonsdottir, G. A., Ruotti, V., Stewart, R. et al. (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
-
107
-
-
39049108141
-
Time to reconsider stem cell ethics: The importance of induced pluripotent cells
-
Holm, S. (2008) Time to reconsider stem cell ethics: the importance of induced pluripotent cells. J.Med. Ethics 34, 63-64
-
(2008)
J.Med. Ethics
, vol.34
, pp. 63-64
-
-
Holm, S.1
|