Islet Regeneration during the Reversal of Autoimmune Diabetes in NOD Mice

Science

Volumn 302, Issue 5648, 2003, Pages 1223-1227

  Kodama, Shohta ^a   Kühtreiber, Willem ^a   Fujimura, Satoshi ^a   Dale, Elizabeth A ^a   Faustman, Denise L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; IMMUNOLOGY; INSULIN; PATIENT TREATMENT;

ANTOIMMUNE DIABETES;

DISEASES;

DNA; FREUND ADJUVANT; INSULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELL DIFFERENTIATION; CELL REGENERATION; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GLUCOSE BLOOD LEVEL; IMMUNOFLUORESCENCE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULITIS; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; SPLEEN CELL; X CHROMOSOME; Y CHROMOSOME;

ANIMALS; ANTIGENS, CD45; AUTOIMMUNITY; BLOOD GLUCOSE; CELL DIFFERENTIATION; CELL FUSION; CELL TRANSPLANTATION; COMBINED MODALITY THERAPY; DIABETES MELLITUS, TYPE 1; FEMALE; FREUND'S ADJUVANT; IN SITU HYBRIDIZATION, FLUORESCENCE; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED NOD; PANCREATIC DUCTS; PLOIDIES; REGENERATION; SPLEEN; STEM CELLS;

ANIMALIA;

EID: 0242582180     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1088949     Document Type: Article

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38. Supported by the Iacocca Foundation, NIH (NIDDK grant P30 DK57521-02), the Cure Diabetes Now Foundation, and the American Autoimmune-Related Diseases Association Foundation. We thank J. Avruch and D. Nathan for helpful discussions and review of the manuscript.