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Volumn 16, Issue 28, 2010, Pages 3124-3131

Mitochondria-targeted antioxidant peptides

Author keywords

Antioxidant peptides; Mitochondria; Oxidative stress

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; CALCIUM ION; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CYTOCHROME C; EBSELEN; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; MESSENGER RNA; MITOCHONDRIAL DNA; MITOE2; MITOQ; MITOQ10; NUCLEIC ACID; PEPTIDE DERIVATIVE; PEROXYNITRITE; PHOSPHONIUM DERIVATIVE; PRODRUG; REACTIVE OXYGEN METABOLITE; SS 01 PEPTIDE; SS 02 PEPTIDE; SS 20 PEPTIDE; SS 31 PEPTIDE; SUPEROXIDE DISMUTASE; TAURINE; TOCOPHEROL; UBIQUINOL; UBIQUINONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 78649897034     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161210793292519     Document Type: Article
Times cited : (82)

References (73)
  • 1
    • 0034083227 scopus 로고    scopus 로고
    • Role of oxidative stress in cardio-vascular diseases
    • Dhalla, NS, Temsah RM, Netticadan T. Role of oxidative stress in cardio-vascular diseases. J Hypertens 2000;18: 655-73.
    • (2000) J Hypertens , vol.18 , pp. 655-673
    • Dhalla, N.S.1    Temsah, R.M.2    Netticadan, T.3
  • 2
    • 33745713661 scopus 로고    scopus 로고
    • Oxidative stress and atherosclerosis
    • Singh U, Jialal I. Oxidative stress and atherosclerosis. Pathophysiology 2006; 13: 129-42.
    • (2006) Pathophysiology , vol.13 , pp. 129-142
    • Singh, U.1    Jialal, I.2
  • 3
    • 0028792111 scopus 로고
    • Lipid peroxidation and antioxidants as biomarkers of tissue damage
    • Gutteridge JM. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem 1995; 41: 1819-28.
    • (1995) Clin Chem , vol.41 , pp. 1819-1828
    • Gutteridge, J.M.1
  • 4
    • 0032404536 scopus 로고    scopus 로고
    • The central executioners of apoptosis: Caspases or mitochondria?
    • Green D, Kroemer G. The central executioners of apoptosis: caspases or mitochondria? Trends Cell Biol 1998; 8: 267-71.
    • (1998) Trends Cell Biol , vol.8 , pp. 267-271
    • Green, D.1    Kroemer, G.2
  • 5
    • 6344285417 scopus 로고    scopus 로고
    • Endothelial cell superoxide generation: Regulation and relevance for cardiovascular pathophysiology
    • Li JM, Shah AM. Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology. Am J Physiol Regul Integr Comp Physiol 2004; 287: R1014-30.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287
    • Li, J.M.1    Shah, A.M.2
  • 6
    • 0037199466 scopus 로고    scopus 로고
    • Mitochondrial integrity and function in atherogenesis
    • Ballinger SW, Patterson C, Knight-Lozano CA, et al. Mitochondrial integrity and function in atherogenesis. Circulation 2002; 106: 544-9.
    • (2002) Circulation , vol.106 , pp. 544-549
    • Ballinger, S.W.1    Patterson, C.2    Knight-Lozano, C.A.3
  • 7
    • 0034733776 scopus 로고    scopus 로고
    • Reactive oxygen species and vascular cell apoptosis in response to angiotensin II and pro-atherosclerosic factors
    • Dimmeler S, Zeiher AM. Reactive oxygen species and vascular cell apoptosis in response to angiotensin II and pro-atherosclerosic factors. Regul Pept 2000; 90: 19-25.
    • (2000) Regul Pept , vol.90 , pp. 19-25
    • Dimmeler, S.1    Zeiher, A.M.2
  • 8
    • 0032924757 scopus 로고    scopus 로고
    • Mitochondrial damage induced by conditions of oxidative stress
    • Kowaltowski AJ, Vercesi AE. Mitochondrial damage induced by conditions of oxidative stress. Free Radic Biol Med 1999; 26: 463-71.
    • (1999) Free Radic Biol Med , vol.26 , pp. 463-471
    • Kowaltowski, A.J.1    Vercesi, A.E.2
  • 9
    • 72449163629 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in atherosclerosis: Mitochondria-targeted antioxidants as potential therapy
    • Victor VM, Apostolova N, Herance R, Hernandez-Mijares A, Rocha M. Oxidative stress and mitochondrial dysfunction in atherosclerosis: mitochondria-targeted antioxidants as potential therapy. Curr Med Chem 2009; 16: 4654-67.
    • (2009) Curr Med Chem , vol.16 , pp. 4654-4667
    • Victor, V.M.1    Apostolova, N.2    Herance, R.3    Hernandez-Mijares, A.4    Rocha, M.5
  • 10
    • 70449431374 scopus 로고    scopus 로고
    • Mitochondrial-targeted antioxidants and oxidative stress: A proteomic prospective study
    • Rocha M, Esplugues JV, Hernandez-Mijares A, Victor VM. Mitochondrial-targeted antioxidants and oxidative stress: a proteomic prospective study. Curr Pharm Des 2009; 15: 3052-62.
    • (2009) Curr Pharm Des , vol.15 , pp. 3052-3062
    • Rocha, M.1    Esplugues, J.V.2    Hernandez-Mijares, A.3    Victor, V.M.4
  • 12
    • 70449421545 scopus 로고    scopus 로고
    • Oxidative stress and cellular homeostasis
    • VM. Oxidative stress and cellular homeostasis. Curr Pharm Des 2009; 15: 2986-7.
    • (2009) Curr Pharm Des , vol.15 , pp. 2986-2987
  • 13
    • 0141504202 scopus 로고    scopus 로고
    • N-acetylcysteine protects mice from lethal endotoxemia by regulating the redox state of immune cells
    • Victor VM, Rocha M, De la Fuente M. N-acetylcysteine protects mice from lethal endotoxemia by regulating the redox state of immune cells. Free Radic Res 2003; 37: 919-29.
    • (2003) Free Radic Res , vol.37 , pp. 919-929
    • Victor, V.M.1    Rocha, M.2    de la Fuente, M.3
  • 14
  • 16
    • 35148863166 scopus 로고    scopus 로고
    • Cytoprotective properties of alpha-tocopherol are related to gene regulation in cultured Dgalactosamine-treated human hepatocytes
    • González R, Collado JA, Nell S, et al. Cytoprotective properties of alpha-tocopherol are related to gene regulation in cultured Dgalactosamine-treated human hepatocytes. Free Radic Biol Med 2007; 43: 1439-52.
    • (2007) Free Radic Biol Med , vol.43 , pp. 1439-1452
    • González, R.1    Collado, J.A.2    Nell, S.3
  • 17
    • 67650702584 scopus 로고    scopus 로고
    • N-acetylcysteine, coenzyme Q10 and superoxide dismutase mimetic prevent mitochondrial cell dysfunction and cell death induced by d-galactosamine in primary culture of human hepatocytes
    • González R, Ferrín G, Hidalgo AB, et al. N-acetylcysteine, coenzyme Q10 and superoxide dismutase mimetic prevent mitochondrial cell dysfunction and cell death induced by d-galactosamine in primary culture of human hepatocytes. Chem Biol Interact 2009; 181(1): 95-106.
    • (2009) Chem Biol Interact , vol.181 , Issue.1 , pp. 95-106
    • González, R.1    Ferrín, G.2    Hidalgo, A.B.3
  • 19
    • 29344446328 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria: A new therapeutic direction
    • Sheu SS, Nauduri D, Anders MW. Targeting antioxidants to mitochondria: a new therapeutic direction. Biochim Biophys Acta 2006; 1762: 256-65.
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 256-265
    • Sheu, S.S.1    Nauduri, D.2    Anders, M.W.3
  • 20
    • 70349545632 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in sepsis: A potential therapy with mitochondria-targeted antioxidants
    • Víctor VM, Esplugues JV, Hernández-Mijares A, Rocha M. Oxidative stress and mitochondrial dysfunction in sepsis: a potential therapy with mitochondria-targeted antioxidants. Infect Disord Drug Targets 2009; 9: 376-89.
    • (2009) Infect Disord Drug Targets , vol.9 , pp. 376-389
    • Víctor, V.M.1    Esplugues, J.V.2    Hernández-Mijares, A.3    Rocha, M.4
  • 24
    • 69949091535 scopus 로고    scopus 로고
    • Mitochondrial complex I impairment in leukocytes from polycystic ovary syndrome patients with insulin resistance
    • Victor VM, Rocha M, Bañuls C, et al. Mitochondrial complex I impairment in leukocytes from polycystic ovary syndrome patients with insulin resistance. J Clin Endocrinol Metab 2009; 94: 3505-12.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3505-3512
    • Victor, V.M.1    Rocha, M.2    Bañuls, C.3
  • 25
    • 16344374718 scopus 로고    scopus 로고
    • Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition
    • Di Lisa F, Bernardi P. Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition. Cardiovasc Res 2005; 66: 222-32.
    • (2005) Cardiovasc Res , vol.66 , pp. 222-232
    • di Lisa, F.1    Bernardi, P.2
  • 26
    • 0031032817 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
    • Yakes FM, Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 1997; 94: 514-9.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 514-519
    • Yakes, F.M.1    van Houten, B.2
  • 27
    • 34247168121 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria: A potential new therapeutic strategy for cardiovascular diseases
    • Victor VM, Rocha M. Targeting antioxidants to mitochondria: a potential new therapeutic strategy for cardiovascular diseases. Curr Pharm Des 2007; 13: 845-63.
    • (2007) Curr Pharm Des , vol.13 , pp. 845-863
    • Victor, V.M.1    Rocha, M.2
  • 28
    • 34447131490 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria and cardiovascular diseases: The effects of mitoquinone
    • Rocha M, Victor VM. Targeting antioxidants to mitochondria and cardiovascular diseases: the effects of mitoquinone. Med Sci Monit 2007; 13: 132-45.
    • (2007) Med Sci Monit , vol.13 , pp. 132-145
    • Rocha, M.1    Victor, V.M.2
  • 29
    • 0027363407 scopus 로고
    • NF-kappa B activation by ultraviolet light not dependent on a nuclear signal
    • Devary Y, Rosette C, DiDonato JA, Karin M. NF-kappa B activation by ultraviolet light not dependent on a nuclear signal. Science 1993; 261: 1442-5.
    • (1993) Science , vol.261 , pp. 1442-1445
    • Devary, Y.1    Rosette, C.2    Didonato, J.A.3    Karin, M.4
  • 30
    • 0027328056 scopus 로고
    • Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF
    • Schulze-Osthoff K, Beyaert R, Vandervoorde V, Haegeman G, Fiers W. Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF. EMBO J 1993; 12: 3095-104.
    • (1993) EMBO J , vol.12 , pp. 3095-3104
    • Schulze-Osthoff, K.1    Beyaert, R.2    Vandervoorde, V.3    Haegeman, G.4    Fiers, W.5
  • 31
    • 0343986284 scopus 로고    scopus 로고
    • Drug delivery to mitochondria: The key to mitochondrial medicine
    • Murphy MP, Smith RA. Drug delivery to mitochondria: the key to mitochondrial medicine. Adv Drug Deliv Rev 2000; 41: 235-50.
    • (2000) Adv Drug Deliv Rev , vol.41 , pp. 235-250
    • Murphy, M.P.1    Smith, R.A.2
  • 32
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace DC. Mitochondrial diseases in man and mouse. Science 1999; 283: 1482-8.
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1
  • 33
    • 33847071146 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria by conjugation to lipophilic cations
    • Murphy MP, Smith RA. Targeting antioxidants to mitochondria by conjugation to lipophilic cations. Annu Rev Pharmacol Toxicol 2007; 47: 629-56.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 629-656
    • Murphy, M.P.1    Smith, R.A.2
  • 34
    • 0348136710 scopus 로고    scopus 로고
    • Mitochondriatargeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants
    • Jauslin ML, Meier T, Smith RA, Murphy MP. Mitochondriatargeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants. FASEB J 2003; 17: 1972-4.
    • (2003) FASEB J , vol.17 , pp. 1972-1974
    • Jauslin, M.L.1    Meier, T.2    Smith, R.A.3    Murphy, M.P.4
  • 35
    • 13044285432 scopus 로고    scopus 로고
    • Mitochondrial disease in superoxide dismutase 2 mutant mice
    • Melov S, Coskun P, Patel M, et al. Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc Natl Acad Sci USA 1999; 96: 846-51.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 846-851
    • Melov, S.1    Coskun, P.2    Patel, M.3
  • 36
    • 0035503501 scopus 로고    scopus 로고
    • Lifespan extension and rescue of spongiform encephalopaty in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics
    • Melov S, Doctrow SR, Schneider JA, et al. Lifespan extension and rescue of spongiform encephalopaty in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics. J Neurosci 2001; 21: 8348-53.
    • (2001) J Neurosci , vol.21 , pp. 8348-8353
    • Melov, S.1    Doctrow, S.R.2    Schneider, J.A.3
  • 37
    • 2342567868 scopus 로고    scopus 로고
    • Oxidative stress, antioxidants, and endothelial function
    • Schulz E, Anter E, Keaney JF. Oxidative stress, antioxidants, and endothelial function. Curr Med Chem 2004; 11: 1093-104.
    • (2004) Curr Med Chem , vol.11 , pp. 1093-1104
    • Schulz, E.1    Anter, E.2    Keaney, J.F.3
  • 38
    • 0042711191 scopus 로고    scopus 로고
    • Mitochondrial-targeted drug and DNA delivery
    • V. Mitochondrial-targeted drug and DNA delivery. Crit Rev Ther Drug Carrier Syst 2003; 20: 1-62.
    • (2003) Crit Rev Ther Drug Carrier Syst , vol.20 , pp. 1-62
  • 40
    • 70349554140 scopus 로고    scopus 로고
    • Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag
    • Ripcke J, Zarse K, Ristow M, Birringer M. Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag. ChemBioChem 2009; 10: 1689-96.
    • (2009) ChemBioChem , vol.10 , pp. 1689-1696
    • Ripcke, J.1    Zarse, K.2    Ristow, M.3    Birringer, M.4
  • 41
    • 75849164405 scopus 로고    scopus 로고
    • Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy) acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: A prodrug strategy for targeting cytoprotective antioxidants to mitochondria
    • Roser KS, Brookes PS, Wojtovich AP, et al. Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy) acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria. Bioorg Med Chem 2010; 18: 1441-8.
    • (2010) Bioorg Med Chem , vol.18 , pp. 1441-1448
    • Roser, K.S.1    Brookes, P.S.2    Wojtovich, A.P.3
  • 44
    • 34248525050 scopus 로고    scopus 로고
    • Targeting lipoic acid to mitochondria: Synthesis and characterization of a triphenylphosphonium-conjugated alphalipoyl derivative
    • Brown SE, Ross MF, Sanjuan-Pla A, Manas AR, Smith RA, Murphy MP. Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated alphalipoyl derivative. Free Radic Biol Med 2007; 42: 1766-80.
    • (2007) Free Radic Biol Med , vol.42 , pp. 1766-1780
    • Brown, S.E.1    Ross, M.F.2    Sanjuan-Pla, A.3    Manas, A.R.4    Smith, R.A.5    Murphy, M.P.6
  • 45
    • 57649233172 scopus 로고    scopus 로고
    • Mitochondria-targeted antioxidants in the treatment of disease
    • Smith RA, Adlam VJ, Blaikie FH, et al. Mitochondria-targeted antioxidants in the treatment of disease. Ann N Y Acad Sci 2008; 1147: 105-11.
    • (2008) Ann N Y Acad Sci , vol.1147 , pp. 105-111
    • Smith, R.A.1    Adlam, V.J.2    Blaikie, F.H.3
  • 46
    • 0346725016 scopus 로고    scopus 로고
    • Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation
    • Filipovska A, Eccles MR, Smith RA, Murphy MP. Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation. FEBS Lett 2004; 556: 180-6.
    • (2004) FEBS Lett , vol.556 , pp. 180-186
    • Filipovska, A.1    Eccles, M.R.2    Smith, R.A.3    Murphy, M.P.4
  • 47
    • 20244381138 scopus 로고    scopus 로고
    • Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology
    • Ross MF, Kelso GF, Blaikie FH, et al. Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology. Biochemistry (Mosc.) 2005; 70: 222-30.
    • (2005) Biochemistry (Mosc.) , vol.70 , pp. 222-230
    • Ross, M.F.1    Kelso, G.F.2    Blaikie, F.H.3
  • 48
    • 19644398798 scopus 로고    scopus 로고
    • Inhibition of complex I of the electron transport chain causes O2-mediated mitochondrial outgrowth
    • Koopman WJ, Verkaart S, Visch HJ, et al. Inhibition of complex I of the electron transport chain causes O2-mediated mitochondrial outgrowth. Am J Physiol Cell Physiol 2005; 288: C1440-50.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Koopman, W.J.1    Verkaart, S.2    Visch, H.J.3
  • 49
    • 33750930318 scopus 로고    scopus 로고
    • Complex I dysfunction and tolerance to nitroglycerin: An approach based on mitochondrialtargeted antioxidants
    • Esplugues JV, Rocha M, Nuñez C, et al. Complex I dysfunction and tolerance to nitroglycerin: an approach based on mitochondrialtargeted antioxidants. Circ Res 2006; 99: 1067-75.
    • (2006) Circ Res , vol.99 , pp. 1067-1075
    • Esplugues, J.V.1    Rocha, M.2    Nuñez, C.3
  • 50
    • 73849089805 scopus 로고    scopus 로고
    • Mitochondrialdriven ubiquinone enhances extracellular calcium-dependent nitric oxide production and reduces glycochenodeoxycholic acid-induced cell death in hepatocytes
    • González-Rubio S, Hidalgo AB, Ferrín G, et al. Mitochondrialdriven ubiquinone enhances extracellular calcium-dependent nitric oxide production and reduces glycochenodeoxycholic acid-induced cell death in hepatocytes. Chem Res Toxicol 2009; 22: 1984-91.
    • (2009) Chem Res Toxicol , vol.22 , pp. 1984-1991
    • González-Rubio, S.1    Hidalgo, A.B.2    Ferrín, G.3
  • 52
    • 21744450416 scopus 로고    scopus 로고
    • Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury
    • Adlam VJ, Harrison JC, Porteous CM, et al. Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury. FASEB J 2005; 19: 1088-95.
    • (2005) FASEB J , vol.19 , pp. 1088-1095
    • Adlam, V.J.1    Harrison, J.C.2    Porteous, C.M.3
  • 53
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 2001; 46: 3-26.
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 54
    • 4544370680 scopus 로고    scopus 로고
    • Cell-permeable peptide antioxidants targeted to inner mitocondrial membrane inhibit mitocondrial swelling, oxidative cell death, and reperfusion injury
    • Zhao K, Zhao GM, Wu D, et al. Cell-permeable peptide antioxidants targeted to inner mitocondrial membrane inhibit mitocondrial swelling, oxidative cell death, and reperfusion injury. J Biol Chem 2004; 279: 34682-90.
    • (2004) J Biol Chem , vol.279 , pp. 34682-90
    • Zhao, K.1    Zhao, G.M.2    Wu, D.3
  • 55
    • 33646369165 scopus 로고    scopus 로고
    • Cell-permeable, mitochondrial-targeted, peptide antioxidants
    • Szeto HH. Cell-permeable, mitochondrial-targeted, peptide antioxidants. AAPS J 2006; 8: 277-83.
    • (2006) AAPS J , vol.8 , pp. 277-283
    • Szeto, H.H.1
  • 57
    • 0037215549 scopus 로고    scopus 로고
    • Transcellular transport of a highly polar 3+ net charge opioid tetrapeptide
    • Zhao K, Luo G, Zhao GM, Schiller PW, Szeto HH. Transcellular transport of a highly polar 3+ net charge opioid tetrapeptide. J Pharmacol Exp Ther 2003; 304: 425-32.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 425-432
    • Zhao, K.1    Luo, G.2    Zhao, G.M.3    Schiller, P.W.4    Szeto, H.H.5
  • 58
    • 0029982569 scopus 로고    scopus 로고
    • Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
    • Derossi D, Calvet S, Trembleau A, Brunissen A, Chassaing G, Prochiantz A. Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J Biol Chem 1996; 271: 18188-93.
    • (1996) J Biol Chem , vol.271 , pp. 18188-93
    • Derossi, D.1    Calvet, S.2    Trembleau, A.3    Brunissen, A.4    Chassaing, G.5    Prochiantz, A.6
  • 59
    • 0042232110 scopus 로고    scopus 로고
    • Studies on the internalization mechanism of cationic cell-penetrating peptides
    • Drin G, Cottin S, Blanc E, Rees AR, Temsamani J. Studies on the internalization mechanism of cationic cell-penetrating peptides. J Biol Chem 2003; 278: 31192-201.
    • (2003) J Biol Chem , vol.278 , pp. 31192-201
    • Drin, G.1    Cottin, S.2    Blanc, E.3    Rees, A.R.4    Temsamani, J.5
  • 60
    • 0037196557 scopus 로고    scopus 로고
    • Mechanism of tert-butylhydroperoxide-induced apoptosis in rat hepatocytes: Involvement of mitochondria and endoplasmic reticulum
    • Haidara K, Morel I, Abalea V, Gascon BM, Denizeau F. Mechanism of tert-butylhydroperoxide-induced apoptosis in rat hepatocytes: involvement of mitochondria and endoplasmic reticulum. Biochim Biophys Acta 2002; 1542: 173-85.
    • (2002) Biochim Biophys Acta , vol.1542 , pp. 173-185
    • Haidara, K.1    Morel, I.2    Abalea, V.3    Gascon, B.M.4    Denizeau, F.5
  • 61
    • 1642493646 scopus 로고    scopus 로고
    • Mitochondria permeability transition-dependent tert-butyl hydroperoxide-induced apoptosis in hepatoma HepG2 cells
    • Piret JP, Arnould T, Fuks B, Chatelain P, Remacle J, Michiels C. Mitochondria permeability transition-dependent tert-butyl hydroperoxide-induced apoptosis in hepatoma HepG2 cells. Biochem Pharmacol 2004; 67: 611-20.
    • (2004) Biochem Pharmacol , vol.67 , pp. 611-620
    • Piret, J.P.1    Arnould, T.2    Fuks, B.3    Chatelain, P.4    Remacle, J.5    Michiels, C.6
  • 62
    • 0035895888 scopus 로고    scopus 로고
    • Selective targeting of a redox-active ubiquinone to mitochondria within cells: Antioxidant and antiapoptotic properties
    • Kelso GF, Porteous CM, Coulter CV, et al. Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. J Biol Chem 2001; 276: 4588-96.
    • (2001) J Biol Chem , vol.276 , pp. 4588-4596
    • Kelso, G.F.1    Porteous, C.M.2    Coulter, C.V.3
  • 63
    • 2342431848 scopus 로고    scopus 로고
    • Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I
    • Batandier C, Leverve X, Fontaine E. Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I. J Biol Chem 2004; 279: 17197-204.
    • (2004) J Biol Chem , vol.279 , pp. 17197-204
    • Batandier, C.1    Leverve, X.2    Fontaine, E.3
  • 64
    • 0034923201 scopus 로고    scopus 로고
    • Pharmacologic treatment of the stunned myocardium: The concepts and the challenges
    • Przyklenk K. Pharmacologic treatment of the stunned myocardium: the concepts and the challenges. Coron Artery Dis 2001; 12: 363-9.
    • (2001) Coron Artery Dis , vol.12 , pp. 363-369
    • Przyklenk, K.1
  • 65
    • 0036073195 scopus 로고    scopus 로고
    • A highly potent peptide analgesic that protects against ischemia-reperfusion-induced myocardial stunning
    • Wu D, Soong Y, Zhao GM, Szeto HH. A highly potent peptide analgesic that protects against ischemia-reperfusion-induced myocardial stunning. Am J Physiol Heart Circ Physiol 2002; 283: 783-91.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. 783-791
    • Wu, D.1    Soong, Y.2    Zhao, G.M.3    Szeto, H.H.4
  • 66
    • 28944431505 scopus 로고    scopus 로고
    • A potent opiate agonist protects against myocardial stunning during myocardial ischemia and reperfusion in rats
    • Song W, Shin J, Lee J, et al. A potent opiate agonist protects against myocardial stunning during myocardial ischemia and reperfusion in rats. Coron Artery Dis 2005; 16: 407-10.
    • (2005) Coron Artery Dis , vol.16 , pp. 407-410
    • Song, W.1    Shin, J.2    Lee, J.3
  • 67
    • 33845979877 scopus 로고    scopus 로고
    • Mitochondrial targeting of islets with the cell permeant anti-oxidant peptide SS-31 reduces islet cell apoptosis and improves post-transplant function
    • Thomas D, Zhao K, Stauffer C, et al. Mitochondrial targeting of islets with the cell permeant anti-oxidant peptide SS-31 reduces islet cell apoptosis and improves post-transplant function. J Am Soc Nephrol 2007; 18: 213-22.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 213-222
    • Thomas, D.1    Zhao, K.2    Stauffer, C.3
  • 68
    • 57349111179 scopus 로고    scopus 로고
    • A novel cell-permeable antioxidant peptide decreases renal tubular apoptosis and damage in unilateral ureteral obstruction
    • Mizuguchi Y, Chen J, Seshan SV, Poppas DP, Szeto HH, Felsen D. A novel cell-permeable antioxidant peptide decreases renal tubular apoptosis and damage in unilateral ureteral obstruction. Am J Physiol Renal Physiol 2008; 295: F1545-53.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Mizuguchi, Y.1    Chen, J.2    Seshan, S.V.3    Poppas, D.P.4    Szeto, H.H.5    Felsen, D.6
  • 69
    • 68949213947 scopus 로고    scopus 로고
    • Mitochondria targeted peptides protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
    • Yang L, Zhao K, Calingasan NY, Luo G, Szeto HH, Beal F. Mitochondria targeted peptides protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Antioxidants & Redox Signaling 2009; 11: 2095-104.
    • (2009) Antioxidants & Redox Signaling , vol.11 , pp. 2095-2104
    • Yang, L.1    Zhao, K.2    Calingasan, N.Y.3    Luo, G.4    Szeto, H.H.5    Beal, F.6
  • 70
    • 0034977198 scopus 로고    scopus 로고
    • In vivo pharmacokinetics of selective mu-opioid peptide agonists
    • Szeto HH, Lovelace JL, Fridland G, et al. In vivo pharmacokinetics of selective mu-opioid peptide agonists. J Pharmacol Exp Ther 2001; 298: 57-61.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 57-61
    • Szeto, H.H.1    Lovelace, J.L.2    Fridland, G.3
  • 71
    • 77950868170 scopus 로고    scopus 로고
    • Cell responses to oxidative stressors
    • Cataldi A. Cell responses to oxidative stressors. Curr Pharm Des 2010; 16(12): 1387-95.
    • (2010) Curr Pharm Des , vol.16 , Issue.12 , pp. 1387-1395
    • Cataldi, A.1
  • 72
    • 70449431374 scopus 로고    scopus 로고
    • Mitochondrial-targeted antioxidants and oxidative stress: A proteomic prospective study
    • Rocha M, Esplugues JV, Hernandez-Mijares A, Victor VM. Mitochondrial-targeted antioxidants and oxidative stress: a proteomic prospective study. Curr Pharm Des 2009; 15(26): 3052-62.
    • (2009) Curr Pharm Des , vol.15 , Issue.26 , pp. 3052-3062
    • Rocha, M.1    Esplugues, J.V.2    Hernandez-Mijares, A.3    Victor, V.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.