Synthesis of biphenylyltetrazole derivatives of 1-aminopyrroles as angiotensin II antagonists

Farmaco

Volumn 54, Issue 1-2, 1999, Pages 64-76

  Attanasi, Orazio A ^a   Colombani, Spartaco M ^b   De Crescentini, Lucia ^a   Giorgi, Raffaello ^b   Monti, Susanna ^b   Perrone, Ada ^a   Perrulli, Francesca R ^a   Renzetti, Anna Rita ^c   Santeusanio, Stefania ^a  

^a UNIVERSITY OF URBINO   (Italy)

^b Laboratori Guidotti SpA   (Italy)

^c Menarini Ricerche SpA   (Italy)

Author keywords

Biphenylyltetrazole; Deprotection; N acylation; N alkylation; Pyrrole

Indexed keywords

ANGIOTENSIN II ANTAGONIST; BIPHENYL DERIVATIVE; LOSARTAN POTASSIUM; PYRROLE; TETRAZOLE DERIVATIVE;

ACYLATION; ALKYLATION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; MOLECULAR MODEL; NONHUMAN; RAT;

ADRENAL CORTEX; ANGIOTENSIN II; ANIMALS; MODELS, MOLECULAR; PYRROLES; RADIOLIGAND ASSAY; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN;

EID: 0032920436     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(98)00100-1     Document Type: Article

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